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1,25-(OH)2-vitamin D3 suppresses the bone-related Runx2/Cbfa1 gene promoter

artículo científico publicado en 2002

1alpha,25-dihydroxy vitamin D(3) induces nuclear matrix association of the 1alpha,25-dihydroxy vitamin D(3) receptor in osteoblasts independently of its ability to bind DNA

artículo científico publicado en 2010

1alpha,25-dihydroxy vitamin D3-enhanced expression of the osteocalcin gene involves increased promoter occupancy of basal transcription regulators and gradual recruitment of the 1alpha,25-dihydroxy vitamin D3 receptor-SRC-1 coactivator complex

scientific journal article

A Proteasome Inhibitor, Bortezomib, Inhibits Breast Cancer Growth and Reduces Osteolysis by Downregulating Metastatic Genes ⬇️

artículo científico publicado el 15 de septiembre de 2010

A RUNX2-HDAC1 co-repressor complex regulates rRNA gene expression by modulating UBF acetylation

artículo científico publicado en 2012

A Runx2 threshold for the cleidocranial dysplasia phenotype

artículo científico publicado en 2008

A central dinucleotide within vitamin D response elements modulates DNA binding and transactivation by the vitamin D receptor in cellular response to natural and synthetic ligands

artículo científico publicado en 2002

A functional N-terminal domain in C/EBPβ-LAP* is required for interacting with SWI/SNF and to repress Ric-8B gene transcription in osteoblasts

artículo científico publicado en 2014

A germline point mutation in Runx1 uncouples its role in definitive hematopoiesis from differentiation

artículo científico publicado en 2013

A microRNA signature for a BMP2-induced osteoblast lineage commitment program

artículo científico publicado en 2008

A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice

scientific article published on 13 September 2016

A network connecting Runx2, SATB2, and the miR-23a~27a~24-2 cluster regulates the osteoblast differentiation program

artículo científico publicado en 2010

A perspective on malignancy in the marrow

artículo científico publicado en 2017

A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2

scientific journal article

Acidic fibroblast growth factor modulates gene expression in the rat thyroid in vivo

artículo científico publicado el 1 de diciembre de 1992

Activation of the bone-related Runx2/Cbfa1 promoter in mesenchymal condensations and developing chondrocytes of the axial skeleton

artículo científico publicado en 2002

Ajulemic acid, a nonpsychoactive cannabinoid acid, suppresses osteoclastogenesis in mononuclear precursor cells and induces apoptosis in mature osteoclast-like cells

artículo científico publicado en 2008

Alterations in intranuclear localization of Runx2 affect biological activity

artículo científico publicado en 2006

Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network

artículo científico publicado en 2009

Altered chromatin modifications in AML1/RUNX1 breakpoint regions involved in (8;21) translocation.

artículo científico publicado en 2009

An AML1-ETO/miR-29b-1 regulatory circuit modulates phenotypic properties of acute myeloid leukemia cells

artículo científico publicado en 2017

An architectural genetic and epigenetic perspective

scientific article published on 24 December 2010

An architectural perspective of cell-cycle control at the G1/S phase cell-cycle transition.

artículo científico publicado en 2006

An architectural perspective of vitamin D responsiveness.

artículo científico publicado en 2007

Analysis of in vivo gene expression using epitope-tagged proteins

artículo científico publicado en 2004

Antagonizing miR-218-5p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells

artículo científico publicado en 2016

Arachidonic acid, eicosanoids, and fracture repair

artículo científico publicado el 1 de septiembre de 2010

Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information

artículo científico publicado en 2010

Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironments

artículo científico publicado en 2010

Author Correction: Temporal dynamic reorganization of 3D chromatin architecture in hormone-induced breast cancer and endocrine resistance

artículo científico publicado en 2020

BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network.

artículo científico publicado en 2006

Biological effects of the plant-derived polyphenol resveratrol in human articular cartilage and chondrosarcoma cells

artículo científico publicado en 2012

Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation

scientific article published on 02 April 2009

Bivalent Epigenetic Control of Oncofetal Gene Expression in Cancer

artículo científico publicado en 2017

Bone marrow-derived heparan sulfate potentiates the osteogenic activity of bone morphogenetic protein-2 (BMP-2)

artículo científico publicado en 2012

Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells

scientific journal article

Bookmarking target genes in mitosis: a shared epigenetic trait of phenotypic transcription factors and oncogenes?

artículo científico publicado en 2014

Bookmarking the genome: maintenance of epigenetic information.

artículo científico publicado en 2011

Brg1, the ATPase subunit of the SWI/SNF chromatin remodeling complex, is required for myeloid differentiation to granulocytes

artículo científico publicado en 2006

C-ing the Genome: A Compendium of Chromosome Conformation Capture Methods to Study Higher-Order Chromatin Organization

artículo científico publicado en 2016

C/EBPβ binds the P1 promoter of the Runx2 gene and up-regulates Runx2 transcription in osteoblastic cells

artículo científico publicado en 2011

CBFβ and the leukemogenic fusion protein CBFβ-SMMHC associate with mitotic chromosomes to epigenetically regulate ribosomal genes

artículo científico publicado en 2014

CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression.

artículo científico publicado en 2001

CDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-P

artículo científico publicado en 2009

Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility ⬇️

artículo científico publicado en 2010

Canonical WNT Signaling Promotes Osteogenesis by Directly StimulatingRunx2Gene Expression

artículo científico publicado en 2005

Cbfbeta interacts with Runx2 and has a critical role in bone development

scientific journal article

Cell cycle dependent phosphorylation and subnuclear organization of the histone gene regulator p220(NPAT) in human embryonic stem cells.

artículo científico publicado en 2007

Cell cycle gene expression networks discovered using systems biology: Significance in carcinogenesis

artículo científico publicado en 2015

Cell cycle related modulations in Runx2 protein levels are independent of lymphocyte enhancer-binding factor 1 (Lef1) in proliferating osteoblasts

artículo científico publicado en 2007

Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts ⬇️

artículo científico publicado el 1 de septiembre de 2003

Chromatin dynamics regulate mesenchymal stem cell lineage specification and differentiation to osteogenesis

artículo científico publicado en 2017

Chromatin immunoprecipitation

scientific article published on 01 January 2004

Chromatin immunoprecipitation assays: application of ChIP-on-chip for defining dynamic transcriptional mechanisms in bone cells.

artículo científico publicado en 2008

Chromatin interaction analysis reveals changes in small chromosome and telomere clustering between epithelial and breast cancer cells

artículo científico publicado en 2015

Chromatin remodeling and transcriptional activity of the bone-specific osteocalcin gene require CCAAT/enhancer-binding protein beta-dependent recruitment of SWI/SNF activity

artículo científico publicado en 2006

Chromatin remodeling by SWI/SNF results in nucleosome mobilization to preferential positions in the rat osteocalcin gene promoter

artículo científico publicado en 2007

Chromosomes at Work: Organization of Chromosome Territories in the Interphase Nucleus.

artículo científico publicado en 2015

Co-stimulation of the bone-related Runx2 P1 promoter in mesenchymal cells by SP1 and ETS transcription factors at polymorphic purine-rich DNA sequences (Y-repeats)

artículo científico publicado en 2008

Combinatorial organization of the transcriptional regulatory machinery in biological control and cancer

artículo científico publicado en 2005

Conditional inactivation of the mouse Wwox tumor suppressor gene recapitulates the null phenotype ⬇️

artículo científico publicado el 1 de julio de 2013

Control of mesenchymal lineage progression by microRNAs targeting skeletal gene regulators Trps1 and Runx2.

artículo científico publicado en 2012

Cooperation between p27 and p107 during endochondral ossification suggests a genetic pathway controlled by p27 and p130.

artículo científico publicado en 2007

Coordinate control and selective expression of the full complement of replication-dependent histone H4 genes in normal and cancer cells

artículo científico publicado en 2005

Core Binding Factor β of Osteoblasts Maintains Cortical Bone Mass Via Stabilization of Runx2 in Mice

artículo científico publicado en 2015

Core Binding Factor β of Osteoblasts Maintains Cortical Bone Mass via Stabilization of Runx2 in Mice

artículo científico publicado en 2015

Core binding factor β (CBFβ) is retained in the midbody during cytokinesis

artículo científico publicado en 2014

Core binding factor β of osteoblasts maintains cortical bone mass via stabilization of Runx2 in mice

artículo científico publicado en 2015

Correction: Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation.

artículo científico publicado en 2019

Corrigendum to "Pharmacological targeting of the mammalian clock reveals a novel analgesic for osteoarthritis-induced pain" [GENE 655 (2018) 1-12]

artículo científico publicado en 2018

Could lncRNAs be the missing links in control of mesenchymal stem cell differentiation?

artículo científico publicado en 2015

Cover Image, Volume 232, Number 12, December 2017.

artículo científico publicado en 2017

Crystallization and preliminary X-ray analysis of a domain in the Runx2 transcription factor that interacts with the 1α,25 dihydroxy vitamin D3 receptor

artículo científico publicado en 2007

Cyclin D2 and the CDK substrate p220(NPAT) are required for self-renewal of human embryonic stem cells

artículo científico publicado en 2010

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.

artículo científico publicado en 2009

Development of a predictive miRNA signature for breast cancer risk among high-risk women

artículo científico publicado en 2017

Development of an Experimental Animal Model for Lower Back Pain by Percutaneous Injury-Induced Lumbar Facet Joint Osteoarthritis

artículo científico publicado en 2015

Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse

artículo científico publicado en 2010

Differential gene expression analysis using paraffin-embedded tissues after laser microdissection

artículo científico publicado en 2003

Disruption of Broad Epigenetic Domains in PDAC Cells by HAT Inhibitors

scientific article published on 02 June 2019

Dissection of Individual Prostate Lobes in Mouse Models of Prostate Cancer to Obtain High Quality RNA.

artículo científico publicado en 2016

Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene.

artículo científico publicado en 2004

Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression

artículo científico publicado en 2009

Effects of miR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1 ⬇️

artículo científico publicado el 1 de agosto de 2011

Elastomeric high-mineral content hydrogel-hydroxyapatite composites for orthopedic applications.

artículo científico publicado en 2009

Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma.

artículo científico publicado en 2008

Enhanced fracture repair by leukotriene antagonism is characterized by increased chondrocyte proliferation and early bone formation: a novel role of the cysteinyl LT-1 receptor

artículo científico publicado en 2009

Enhancer of Zeste Homolog 2 Inhibition Stimulates Bone Formation and Mitigates Bone Loss Caused by Ovariectomy in Skeletally Mature Mice

artículo científico publicado en 2016

Environmental disruption of circadian rhythm predisposes mice to osteoarthritis-like changes in knee joint

artículo científico publicado en 2015

Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2

artículo científico publicado en 2015

Epigenetic Control of the Bone-master Runx2 Gene during Osteoblast-lineage Commitment by the Histone Demethylase JARID1B/KDM5B.

artículo científico publicado en 2015

Epigenetic Modulation in Periodontitis: Interaction of Adiponectin and JMJD3-IRF4 Axis in Macrophages

artículo científico publicado en 2015

Epigenetic control of cell cycle-dependent histone gene expression is a principal component of the abbreviated pluripotent cell cycle.

artículo científico publicado en 2012

Epigenetic landscape during osteoblastogenesis defines a differentiation-dependent Runx2 promoter region.

artículo científico publicado en 2014

Epigenetic mechanisms in leukemia

artículo científico

Epigenetic pathways regulating bone homeostasis: potential targeting for intervention of skeletal disorders

artículo científico publicado en 2014

Epigenetic regulation of early osteogenesis and mineralized tissue formation by a HOXA10-PBX1-associated complex

artículo científico publicado en 2011

Epithelial-to-mesenchymal transition and cancer stem cells contribute to breast cancer heterogeneity

artículo científico publicado en 2018

Establishment of histone gene regulation and cell cycle checkpoint control in human embryonic stem cells

artículo científico publicado en 2007

Estrogen Receptor-α Is Developmentally Regulated during Osteoblast Differentiation and Contributes to Selective Responsiveness of Gene Expression

Estrogen receptor α mediates proliferation of osteoblastic cells stimulated by estrogen and mechanical strain, but their acute down-regulation of the Wnt antagonist Sost is mediated by estrogen receptor β.

artículo científico publicado en 2013

Ethanol Extract of Cissus quadrangularis Enhances Osteoblast Differentiation and Mineralization of Murine Pre-Osteoblastic MC3T3-E1 Cells

artículo científico publicado en 2016

Ethyl acetate and n-butanol fraction of Cissus quadrangularis promotes the mineralization potential of murine pre-osteoblast cell line MC3T3-E1 (sub-clone 4)

scientific article published on 15 November 2018

Expression of Ribosomal RNA and Protein Genes in Human Embryonic Stem Cells Is Associated With the Activating H3K4me3 Histone Mark

artículo científico publicado en 2016

Expression of Runx2 transcription factor in non-skeletal tissues, sperm and brain

artículo científico publicado en 2008

Expression of secreted frizzled related protein 1, a Wnt antagonist, in brain, kidney, and skeleton is dispensable for normal embryonic development

artículo científico publicado en 2008

Expression of the IL-11 Gene in Metastatic Cells Is Supported by Runx2-Smad and Runx2-cJun Complexes Induced by TGFβ1

artículo científico publicado en 2015

Expression of the ectodomain-releasing protease ADAM17 is directly regulated by the osteosarcoma and bone-related transcription factor RUNX2

artículo científico publicado en 2018

Expression of the osteoblast differentiation factor RUNX2 (Cbfa1/AML3/Pebp2alpha A) is inhibited by tumor necrosis factor-alpha

artículo científico publicado en 2001

Ezh2-dependent H3K27me3 modification dynamically regulates vitamin D3-dependent epigenetic control of CYP24A1 gene expression in osteoblastic cells

scientific article published on 07 January 2020

Fidelity of Runx2 activity in breast cancer cells is required for the generation of metastases-associated osteolytic disease.

artículo científico publicado en 2004

Fidelity of histone gene regulation is obligatory for genome replication and stability

artículo científico publicado en 2014

Forced expression of the interferon regulatory factor 2 oncoprotein causes polyploidy and cell death in FDC-P1 myeloid hematopoietic progenitor cells

artículo científico publicado en 2002

Four novel RUNX2 mutations including a splice donor site result in the cleidocranial dysplasia phenotype.

artículo científico publicado en 2006

Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression

artículo científico publicado en 2010

Functional architecture of the nucleus: organizing the regulatory machinery for gene expression, replication and repair.

artículo científico publicado en 2003

Functional characterization of a human histone gene cluster duplication

artículo científico publicado en 2004

Functional coupling of transcription factor HiNF-P and histone H4 gene expression during pre- and post-natal mouse development.

artículo científico publicado en 2011

Gene profiling of cell cycle progression through S-phase reveals sequential expression of genes required for DNA replication and nucleosome assembly

artículo científico publicado en 2002

Genetic ablation of the CDP/Cux protein C terminus results in hair cycle defects and reduced male fertility

scientific journal article

Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer

scientific article published on August 2008

Genome-Wide Studies Reveal that H3K4me3 Modification in Bivalent Genes Is Dynamically Regulated during the Pluripotent Cell Cycle and Stabilized upon Differentiation.

artículo científico

Genome-wide DNase hypersensitivity, and occupancy of RUNX2 and CTCF reveal a highly dynamic gene regulome during MC3T3 pre-osteoblast differentiation

artículo científico publicado en 2017

Genome-wide co-occupancy of AML1-ETO and N-CoR defines the t(8;21) AML signature in leukemic cells

artículo científico publicado en 2015

Genome-wide screening in human growth plates during puberty in one patient suggests a role for RUNX2 in epiphyseal maturation.

artículo científico publicado en 2011

Genomic occupancy of HLH, AP1 and Runx2 motifs within a nuclease sensitive site of the Runx2 gene

artículo científico publicado en 2013

Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis.

artículo científico publicado en 2014

Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility

artículo científico publicado en 2011

Glycosaminoglycans modulate RANKL-induced osteoclastogenesis

artículo científico publicado en 2010

HOXA10 controls osteoblastogenesis by directly activating bone regulatory and phenotypic genes.

artículo científico publicado en 2007

Heparan sulfate enhances the self-renewal and therapeutic potential of mesenchymal stem cells from human adult bone marrow

artículo científico publicado en 2012

Heparan sulfate proteoglycans and human breast cancer epithelial cell tumorigenicity

artículo científico publicado en 2014

Heparan sulfate regulates the anabolic activity of MC3T3-E1 preosteoblast cells by induction of Runx2.

artículo científico publicado en 2007

HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition.

artículo científico publicado en 2005

HiNF-P is a bifunctional regulator of cell cycle controlled histone H4 gene transcription

artículo científico publicado en 2007

High throughput analysis of differential gene expression

artículo científico publicado en 1998

High-resolution molecular validation of self-renewal and spontaneous differentiation in clinical-grade adipose-tissue derived human mesenchymal stem cells.

artículo científico publicado en 2014

Higher order genomic organization and epigenetic control maintain cellular identity and prevent breast cancer

scientific article published on 15 March 2019

Higher order genomic organization and regulatory compartmentalization for cell cycle control at the G1/S-phase transition

scientific article published on 10 May 2018

Histone H3 lysine 4 acetylation and methylation dynamics define breast cancer subtypes

artículo científico publicado en 2016

Histone H4 Methyltransferase Suv420h2 Maintains Fidelity of Osteoblast Differentiation

artículo científico publicado en 2016

Histone acetylation in vivo at the osteocalcin locus is functionally linked to vitamin D-dependent, bone tissue-specific transcription

artículo científico publicado en 2002

Histone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cells

artículo científico publicado en 2015

Human embryonic stem cell registries: value, challenges and opportunities

artículo científico publicado en 2008

Human embryonic stem cells are pre-mitotically committed to self-renewal and acquire a lengthened G1 phase upon lineage programming

artículo científico publicado en 2010

Hyaluronic acid-based hydrogels functionalized with heparin that support controlled release of bioactive BMP-2

artículo científico publicado en 2012

Identification of HiNF-P, a Key Activator of Cell Cycle-Controlled Histone H4 Genes at the Onset of S Phase ⬇️

artículo científico publicado el 1 de noviembre de 2003

Identification of RUNX3 as a component of the MST/Hpo signaling pathway

artículo científico publicado en 2012

Identification of novel protein/DNA interactions within the promoter of the bone-related transcription factor Runx2/Cbfa1.

artículo científico publicado en 2002

Identification of tRNA-derived small RNA (tsRNA) responsive to the tumor suppressor, RUNX1, in breast cancer

artículo científico publicado en 2020

Identifying Nuclear Matrix-Attached DNA Across the Genome

artículo científico

Immunofluorescence analysis using epitope-tagged proteins: in vitro system

scientific article published on 01 January 2004

Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbfbeta in osteosarcoma cells

artículo científico publicado en 2009

Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.

artículo científico publicado en 2005

In situ immunofluorescence analysis: analyzing RNA synthesis by 5-bromouridine-5'-triphosphate labeling

artículo científico publicado en 2004

In situ immunofluorescence analysis: immunofluorescence microscopy

scientific article published on 01 January 2004

In situ nuclear organization of regulatory machinery

artículo científico publicado en 2008

Inhibition of the RUNX1-CBFβ transcription factor complex compromises mammary epithelial cell identity: a phenotype potentially stabilized by mitotic gene bookmarking

scientific article published on 30 June 2020

Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites

artículo científico publicado en 2002

Integrin αvβ6 promotes an osteolytic program in cancer cells by upregulating MMP2.

artículo científico

Interaction of the 1alpha,25-dihydroxyvitamin D3 receptor at the distal promoter region of the bone-specific osteocalcin gene requires nucleosomal remodelling

scientific journal article

International stem cell registries.

artículo científico publicado en 2010

Intranuclear Trafficking: Organization and Assembly of Regulatory Machinery for Combinatorial Biological Control

artículo científico publicado en 2004

Intranuclear and higher-order chromatin organization of the major histone gene cluster in breast cancer.

artículo científico publicado en 2017

Intranuclear organization of RUNX transcriptional regulatory machinery in biological control of skeletogenesis and cancer

artículo científico publicado en 2003

Intranuclear trafficking of transcription factors: Requirements for vitamin D-mediated biological control of gene expression.

artículo científico publicado en 2003

Intricate gene regulatory networks of helix-loop-helix (HLH) proteins support regulation of bone-tissue related genes during osteoblast differentiation

artículo científico publicado en 2008

Lineage-Specific Early Differentiation of Human Embryonic Stem Cells Requires a G2 Cell Cycle Pause.

artículo científico publicado en 2016

Linkages of nuclear architecture to biological and pathological control of gene expression

artículo científico publicado en 1998

Live cell imaging of the cancer-related transcription factor RUNX2 during mitotic progression

artículo científico publicado en 2011

Loss of RUNX1 is associated with aggressive lung adenocarcinomas.

artículo científico publicado en 2017

Lymphocyte enhancer-binding factor 1 (Lef1) inhibits terminal differentiation of osteoblasts

artículo científico publicado en 2006

Maintenance of open chromatin and selective genomic occupancy at the cell cycle-regulated histone H4 promoter during differentiation of HL-60 promyelocytic leukemia cells

artículo científico publicado en 2003

Maternal expression and early induction of histone gene transcription factor Hinfp sustains development in pre-implantation embryos

artículo científico publicado en 2016

Mechanical strain-mediated reduction in RANKL expression is associated with RUNX2 and BRD2

scientific article published on 16 January 2020

Metastatic bone disease: role of transcription factors and future targets

artículo científico publicado en 2010

MicroRNA control of bone formation and homeostasis

artículo científico publicado en 2012

MicroRNA functions in osteogenesis and dysfunctions in osteoporosis

artículo científico publicado en 2013

MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma

artículo científico publicado en 2013

MicroRNA-378-mediated suppression of Runx1 alleviates the aggressive phenotype of triple-negative MDA-MB-231 human breast cancer cells.

artículo científico publicado en 2016

MicroRNA-466 inhibits tumor growth and bone metastasis in prostate cancer by direct regulation of osteogenic transcription factor RUNX2.

artículo científico publicado en 2017

MicroRNAs 221 and 222 bypass quiescence and compromise cell survival

artículo científico publicado en 2008

MicroRNAs in the control of metastatic bone disease

artículo científico publicado en 2014

Microtubule-dependent nuclear-cytoplasmic shuttling of Runx2.

artículo científico publicado en 2006

Mitotic Gene Bookmarking: An Epigenetic Mechanism for Coordination of Lineage Commitment, Cell Identity and Cell Growth

artículo científico publicado en 2017

Mitotic Gene Bookmarking: An Epigenetic Program to Maintain Normal and Cancer Phenotypes

artículo científico publicado en 2018

Mitotic Inheritance of mRNA Facilitates Translational Activation of the Osteogenic-Lineage Commitment Factor Runx2 in Progeny of Osteoblastic Cells.

artículo científico publicado en 2015

Mitotic bookmarking of genes: a novel dimension to epigenetic control.

artículo científico publicado en 2010

Mitotic control of RUNX2 phosphorylation by both CDK1/cyclin B kinase and PP1/PP2A phosphatase in osteoblastic cells

artículo científico publicado en 2007

Mitotic gene bookmarking by RUNX1 contributes to stabilization of the normal mammary epithelial phenotype

article

Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.

artículo científico publicado en 2007

Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells

scientific journal article

Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2.

artículo científico publicado en 2007

Mitotically-associated lncRNA (MANCR) Affects Genomic Stability and Cell Division in Aggressive Breast Cancer.

artículo científico publicado en 2018

Mll-COMPASS complexes mediate H3K4me3 enrichment and transcription of the osteoblast master gene Runx2/p57 in osteoblasts

scientific article published on 07 September 2018

Molecular switches involving homeodomain proteins, HOXA10 and RUNX2 regulate osteoblastogenesis

artículo científico publicado en 2008

Molecular targets for radiation oncology in prostate cancer.

artículo científico publicado en 2011

Mst1 is an interacting protein that mediates PHLPPs' induced apoptosis

artículo científico publicado en 2010

Multiple levels of epigenetic control for bone biology and pathology

artículo científico publicado en 2015

Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins

artículo científico publicado en 2002

Nanoparticle-based targeted cancer strategies for non-invasive prostate cancer intervention.

artículo científico publicado en 2018

Networks and hubs for the transcriptional control of osteoblastogenesis.

artículo científico publicado en 2006

Nkx3.2-mediated repression of Runx2 promotes chondrogenic differentiation

scientific journal article

Nomenclature for Runt-related (RUNX) proteins

artículo científico publicado en 2004

Non-coding RNAs: Epigenetic regulators of bone development and homeostasis

artículo científico

Nuclear coactivator-62 kDa/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D receptor-mediated transcription and RNA splicing

artículo científico publicado en 2003

Nuclear microenvironments and cancer

artículo científico publicado en 2008

Nuclear microenvironments in biological control and cancer.

artículo científico publicado en 2007

Nuclear microenvironments support assembly and organization of the transcriptional regulatory machinery for cell proliferation and differentiation

artículo científico publicado en 2004

Nuclear microenvironments support physiological control of gene expression

artículo científico publicado en 2003

Nuclear organization mediates cancer-compromised genetic and epigenetic control

artículo científico publicado en 2018

Nucleosome organization and targeting of SWI/SNF chromatin-remodeling complexes: contributions of the DNA sequence

artículo científico publicado en 2007

Oncofetal Epigenetic Bivalency in Breast Cancer Cells: H3K4 and H3K27 Tri-Methylation as a Biomarker for Phenotypic Plasticity

artículo científico publicado en 2016

Oncogenic cooperation between PI3K/Akt signaling and transcription factor Runx2 promotes the invasive properties of metastatic breast cancer cells

artículo científico publicado en 2013

Oncogenic epigenetic control.

artículo científico publicado en 2016

Organization of transcriptional regulatory machinery in nuclear microenvironments: implications for biological control and cancer

artículo científico publicado en 2007

Organization of transcriptional regulatory machinery in osteoclast nuclei: compartmentalization of Runx1.

artículo científico publicado en 2005

Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer

artículo científico publicado en 2009

Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling

artículo científico publicado en 2006

Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells

artículo científico publicado en 2003

Osteocalcin gene promoter: Unlocking the secrets for regulation of osteoblast growth and differentiation

artículo científico publicado en 1998

Osteogenic potential of hexane and dichloromethane fraction of Cissus quadrangularis on murine preosteoblast cell line MC3T3-E1 (subclone 4)

artículo científico publicado en 2019

Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development

scientific journal article

Participation of integrin β3 in osteoblast differentiation induced by titanium with nano or microtopography

artículo científico publicado en 2019

Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors

artículo científico publicado en 2010

Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice

artículo científico publicado en 2008

Pharmacological targeting of the mammalian clock reveals a novel analgesic for osteoarthritis-induced pain.

artículo científico publicado en 2018

Phenotype discovery by gene expression profiling: mapping of biological processes linked to BMP-2-mediated osteoblast differentiation

artículo científico publicado en 2003

Phenotypic transcription factors epigenetically mediate cell growth control.

artículo científico publicado en 2008

Phosphorylation at serine 208 of the 1alpha,25-dihydroxy Vitamin D3 receptor modulates the interaction with transcriptional coactivators

artículo científico publicado en 2007

Pin1-mediated Runx2 modification is critical for skeletal development

artículo científico publicado en 2013

Planar cell polarity aligns osteoblast division in response to substrate strain

artículo científico publicado en 2015

Pluripotency: toward a gold standard for human ES and iPS cells

artículo científico publicado en 2009

Point mutation in AML1 disrupts subnuclear targeting, prevents myeloid differentiation, and effects a transformation-like phenotype.

artículo científico publicado en 2005

Polyalanine repeat polymorphism in RUNX2 is associated with site-specific fracture in post-menopausal females

artículo científico publicado en 2013

Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer.

scientific article published on 24 July 2009

Post-proliferative cyclin E-associated kinase activity in differentiated osteoblasts: Inhibition by proliferating osteoblasts and osteosarcoma cells

scholarly article by Elisheva Smith published in August 1997

Preclinical characterization of mitochondria-targeted small molecule hsp90 inhibitors, gamitrinibs, in advanced prostate cancer

artículo científico publicado en 2010

Precocious Phenotypic Transcription-Factor Expression During Early Development.

artículo científico publicado en 2016

Primary mouse embryonic fibroblasts: A model of mesenchymal cartilage formation

article

Profiling of human epigenetic regulators using a semi-automated real-time qPCR platform validated by next generation sequencing

artículo científico publicado en 2017

Prostate cancer regulatory networks

artículo científico publicado en 2009

Prostate carcinoma and radiation therapy: therapeutic treatment resistance and strategies for targeted therapeutic intervention

artículo científico publicado en 2008

Protein-deoxyribonucleic acid interactions linked to gene expression: DNase I digestion.

artículo científico publicado en 2004

Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay

scientific article published on 01 January 2004

Protein-deoxyribonucleic acid interactions linked to gene expression: ligation-mediated polymerase chain reaction

artículo científico publicado en 2004

Proteomic Analysis of Exosomes and Exosome-Free Conditioned Media From Human Osteosarcoma Cell Lines Reveals Secretion of Proteins Related to Tumor Progression.

artículo científico

Quantitative signature for architectural organization of regulatory factors using intranuclear informatics.

artículo científico publicado en 2004

RUNX1 and RUNX2 transcription factors function in opposing roles to regulate breast cancer stem cells

artículo científico publicado en 2020

RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells.

artículo científico publicado en 2016

RUNX1-dependent mechanisms in biological control and dysregulation in cancer

artículo científico publicado en 2018

Real-time detection of breast cancer at the cellular level

artículo científico publicado en 2018

Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation

artículo científico publicado en 2007

Recruitment and subnuclear distribution of the regulatory machinery during 1alpha,25-dihydroxy vitamin D3-mediated transcriptional upregulation in osteoblasts

artículo científico publicado en 2010

Redefining the activity of a bone-specific transcription factor: Novel insights for understanding bone formation ⬇️

artículo científico publicado el 1 de octubre de 2013

Reduced CpG methylation is associated with transcriptional activation of the bone-specific rat osteocalcin gene in osteoblasts

artículo científico publicado en 2002

Regulation of osteogenesis by long noncoding RNAs: An epigenetic mechanism contributing to bone formation

artículo científico publicado en 2018

Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity

scientific journal article

Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

artículo científico publicado en 2004

Reprogramming the pluripotent cell cycle: restoration of an abbreviated G1 phase in human induced pluripotent stem (iPS) cells

artículo científico publicado en 2011

Resolution of inflammation induces osteoblast function and regulates the Wnt signaling pathway

artículo científico publicado en 2012

Ribonucleoprotein immunoprecipitation (RNP-IP): a direct in vivo analysis of microRNA-targets

artículo científico publicado en 2010

Role of the WWOX tumor suppressor gene in bone homeostasis and the pathogenesis of osteosarcoma ⬇️

artículo científico publicado el 3 de abril de 2011

Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination

artículo científico publicado en 2009

Runx1 Activities in Superficial Zone Chondrocytes, Osteoarthritic Chondrocyte Clones and Response to Mechanical Loading

artículo científico publicado en 2015

Runx1 is associated with breast cancer progression in MMTV-PyMT transgenic mice and its depletion in vitro inhibits migration and invasion

artículo científico publicado en 2015

Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition

artículo científico publicado en 2017

Runx1/AML1 hematopoietic transcription factor contributes to skeletal development in vivo.

artículo científico publicado en 2003

Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter

artículo científico publicado en 2002

Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression

artículo científico publicado en 2004

Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential.

artículo científico publicado en 2007

Runx2 induces acute myeloid leukemia in cooperation with Cbfbeta-SMMHC in mice

artículo científico publicado en 2009

Runx2 mediates epigenetic silencing of the bone morphogenetic protein-3B (BMP-3B/GDF10) in lung cancer cells ⬇️

artículo científico publicado el 18 de junio de 2012

Runx2 protein expression utilizes the Runx2 P1 promoter to establish osteoprogenitor cell number for normal bone formation

artículo científico publicado en 2011

Runx2 protein represses Axin2 expression in osteoblasts and is required for craniosynostosis in Axin2-deficient mice

artículo científico publicado en 2013

Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors

artículo científico publicado en 2008

Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells

scientific article published on October 2008

Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).

artículo científico publicado en 2009

Runx2-Smad signaling impacts the progression of tumor-induced bone disease

artículo científico publicado en 2014

Runx2/Cbfa1 functions: diverse regulation of gene transcription by chromatin remodeling and co-regulatory protein interactions

artículo científico publicado en 2003

SAT-573 Characterization of the Gene Expression Program of a Mutant Thyroid Hormone Receptor in Anaplastic Thyroid Cancer

SMARCA4 regulates gene expression and higher-order chromatin structure in proliferating mammary epithelial cells

scientific article published on 19 July 2016

SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation

scientific journal article

SWI/SNF-independent nuclease hypersensitivity and an increased level of histone acetylation at the P1 promoter accompany active transcription of the bone master gene Runx2.

scientific article published on August 2009

Secreted frizzled related protein 1 is a target to improve fracture healing

artículo científico publicado en 2009

Secreted frizzled related protein 1 regulates Wnt signaling for BMP2 induced chondrocyte differentiation

artículo científico publicado en 2006

Selective expression of long non-coding RNAs in a breast cancer cell progression model

artículo científico publicado en 2017

Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase

artículo científico publicado en 2006

Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription.

artículo científico publicado en 2005

Species-specific biological effects of FGF-2 in articular cartilage: implication for distinct roles within the FGF receptor family

artículo científico publicado en 2012

Specific residues of RUNX2 are obligatory for formation of BMP2-induced RUNX2-SMAD complex to promote osteoblast differentiation.

artículo científico publicado en 2008

Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cells

artículo científico publicado en 2008

Standardizing analysis of circulating microRNA: clinical and biological relevance

artículo científico publicado en 2014

Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.

artículo científico publicado en 2008

Suberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts.

artículo científico publicado en 2011

Subnuclear domain proteins in cancer cells support the functions of RUNX2 in the DNA damage response

artículo científico publicado en 2015

Subnuclear localization and intranuclear trafficking of transcription factors

artículo científico publicado en 2010

Subnuclear targeting of Runx1 is required for synergistic activation of the myeloid specific M-CSF receptor promoter by PU.1.

artículo científico publicado en 2005

Subnuclear targeting of the Runx3 tumor suppressor and its epigenetic association with mitotic chromosomes.

artículo científico publicado en 2009

Sulfated glycosaminoglycans mediate the effects of FGF2 on the osteogenic potential of rat calvarial osteoprogenitor cells

scientific journal article

Survival responses of human embryonic stem cells to DNA damage

artículo científico publicado en 2009

Switches in histone modifications epigenetically control vitamin D3-dependent transcriptional upregulation of the CYP24A1 gene in osteoblastic cells

artículo científico publicado en 2019

Synergism between Wnt3a and heparin enhances osteogenesis via a phosphoinositide 3-kinase/Akt/RUNX2 pathway

artículo científico publicado en 2010

TIEG1/KLF10 modulates Runx2 expression and activity in osteoblasts

artículo científico publicado en 2011

TRAP-1, the mitochondrial Hsp90.

artículo científico

Targeted ablation of the WW domain-containing oxidoreductase tumor suppressor leads to impaired steroidogenesis

artículo científico publicado en 2008

Targeted deletion of Wwox reveals a tumor suppressor function

artículo científico publicado en 2007

Targeting deregulated epigenetic control in cancer ⬇️

artículo científico publicado el 1 de noviembre de 2013

Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease

artículo científico publicado en 2015

Targeting of the YY1 transcription factor to the nucleolus and the nuclear matrix in situ: The C-terminus is a principal determinant for nuclear trafficking

artículo científico publicado en 1998

Temporal and spatial parameters of skeletal gene expression: targeting RUNX factors and their coregulatory proteins to subnuclear domains

artículo científico publicado en 2003

Temporal dynamic reorganization of 3D chromatin architecture in hormone-induced breast cancer and endocrine resistance

artículo científico publicado en 2019

The 1alpha,25-dihydroxy Vitamin D3 receptor preferentially recruits the coactivator SRC-1 during up-regulation of the osteocalcin gene

artículo científico publicado en 2007

The BRG1 ATPase of human SWI/SNF chromatin remodeling enzymes as a driver of cancer

artículo científico publicado en 2017

The BRG1 chromatin remodeling enzyme links cancer cell metabolism and proliferation

artículo científico publicado en 2016

The HiNF-P/p220NPAT cell cycle signaling pathway controls nonhistone target genes

artículo científico publicado en 2007

The Notch-responsive transcription factor Hes-1 attenuates osteocalcin promoter activity in osteoblastic cells

scientific journal article

The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion

artículo científico publicado en 2005

The Runx2 transcription factor plays a key role in the 1alpha,25-dihydroxy Vitamin D3-dependent upregulation of the rat osteocalcin (OC) gene expression in osteoblastic cells

artículo científico publicado en 2004

The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation

artículo científico publicado en 2015

The Thyroid Hormone Receptor-RUNX2 Axis: A Novel Tumor Suppressive Pathway in Breast Cancer

artículo científico publicado en 2019

The Ultrastructural Signature of Human Embryonic Stem Cells

artículo científico publicado en 2016

The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism

scientific journal article

The Wnt antagonist secreted frizzled-related protein-1 controls osteoblast and osteocyte apoptosis

artículo científico publicado en 2005

The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice

scientific journal article

The abbreviated pluripotent cell cycle.

artículo científico publicado en 2013

The architectural organization of human stem cell cycle regulatory machinery

scientific journal article

The bone-related Zn finger transcription factor Osterix promotes proliferation of mesenchymal cells

artículo científico publicado en 2005

The bone-specific Runx2-P1 promoter displays conserved three-dimensional chromatin structure with the syntenic Supt3h promoter.

artículo científico publicado en 2014

The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts

artículo científico publicado en 2005

The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells.

artículo científico publicado en 2010

The cancer-related transcription factor RUNX2 modulates expression and secretion of the matricellular protein osteopontin in osteosarcoma cells to promote adhesion to endothelial pulmonary cells and lung metastasis

scientific article published on 13 January 2019

The cancer-related transcription factor Runx2 modulates cell proliferation in human osteosarcoma cell lines

artículo científico publicado en 2013

The classic receptor for 1alpha,25-dihydroxy vitamin D3 is required for non-genomic actions of 1alpha,25-dihydroxy vitamin D3 in osteosarcoma cells

artículo científico publicado en 2006

The cleidocranial dysplasia-related R131G mutation in the Runt-related transcription factor RUNX2 disrupts binding to DNA but not CBF-beta

artículo científico publicado en 2010

The connection between BRG1, CTCF and topoisomerases at TAD boundaries

artículo científico publicado en 2017

The core-binding factor beta subunit is required for bone formation and hematopoietic maturation

scientific journal article

The dynamic architectural and epigenetic nuclear landscape: developing the genomic almanac of biology and disease.

artículo científico publicado en 2014

The dynamic organization of gene-regulatory machinery in nuclear microenvironments

artículo científico publicado en 2005

The epigenetic reader Brd4 is required for osteoblast differentiation

artículo científico publicado en 2019

The gene for aromatase, a rate-limiting enzyme for local estrogen biosynthesis, is a downstream target gene of Runx2 in skeletal tissues

artículo científico publicado en 2010

The heparan sulfate proteoglycan (HSPG) glypican-3 mediates commitment of MC3T3-E1 cells toward osteogenesis.

artículo científico publicado en 2009

The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss

artículo científico publicado en 2010

The histone gene activator HINFP is a nonredundant cyclin E/CDK2 effector during early embryonic cell cycles

scientific journal article

The histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motif

artículo científico publicado en 2008

The histone gene transcription factor HiNF-P stabilizes its cell cycle regulatory co-activator p220NPAT.

artículo científico publicado en 2006

The human SWI/SNF complex associates with RUNX1 to control transcription of hematopoietic target genes

artículo científico publicado en 2010

The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing

artículo científico publicado en 2007

The leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes.

artículo científico publicado en 2008

The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblasts

artículo científico publicado en 2009

The osteogenic transcription factor runx2 controls genes involved in sterol/steroid metabolism, including CYP11A1 in osteoblasts

artículo científico publicado en 2009

The role of Runx2 in facilitating autophagy in metastatic breast cancer cells

artículo científico publicado en 2017

The role of cell adhesion in hematopoiesis and leukemogenesis

scientific article published on 13 April 2019

The subnuclear organization of histone gene regulatory proteins and 3' end processing factors of normal somatic and embryonic stem cells is compromised in selected human cancer cell types

artículo científico publicado en 2009

The tumor suppressor interferon regulatory factor 1 interferes with SP1 activation to repress the human CDK2 promoter

artículo científico publicado en 2003

The tyrosine phosphatase, OST-PTP, is expressed in mesenchymal progenitor cells early during skeletogenesis in the mouse

artículo científico publicado en 2004

The vitamin D response element in the distal osteocalcin promoter contributes to chromatin organization of the proximal regulatory domain

artículo científico publicado en 2004

Thyroid Hormone Receptor β Suppression of RUNX2 Is Mediated by Brahma-Related Gene 1-Dependent Chromatin Remodeling

artículo científico publicado en 2018

Thyroid Hormone Receptor-β (TRβ) Mediates Runt-Related Transcription Factor 2 (Runx2) Expression in Thyroid Cancer Cells: A Novel Signaling Pathway in Thyroid Cancer

artículo científico publicado en 2016

Towards a more precise and individualized assessment of breast cancer risk

artículo científico publicado en 2019

Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer

artículo científico publicado en 2009

Transcription factors RUNX1/AML1 and RUNX2/Cbfa1 dynamically associate with stationary subnuclear domains.

artículo científico publicado en 2002

Transcription-factor-mediated epigenetic control of cell fate and lineage commitment

scientific article published on February 2009

Transcriptional Auto-Regulation of RUNX1 P1 Promoter

artículo científico publicado en 2016

Transcriptional activation of the histone nuclear factor P (HiNF-P) gene by HiNF-P and its cyclin E/CDK2 responsive co-factor p220NPAT defines a novel autoregulatory loop at the G1/S phase transition

artículo científico publicado en 2007

Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes

artículo científico publicado en 2010

Transcriptional induction of the osteocalcin gene during osteoblast differentiation involves acetylation of histones h3 and h4.

artículo científico publicado en 2003

Transient RUNX1 Expression during Early Mesendodermal Differentiation of hESCs Promotes Epithelial to Mesenchymal Transition through TGFB2 Signaling

artículo científico publicado en 2016

Tumor suppressor pRB functions as a co-repressor of the CCAAT displacement protein (CDP/cut) to regulate cell cycle controlled histone H4 transcription

artículo científico publicado en 2003

Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription

artículo científico publicado en 2004

Unique Regulatory Mechanisms for the Human Embryonic Stem Cell Cycle.

artículo científico publicado en 2016

Vitamin D control of gene expression: temporal and spatial parameters for organization of the regulatory machinery

artículo científico publicado en 2008

WWOX and p53 Dysregulation Synergize to Drive the Development of Osteosarcoma

artículo científico publicado en 2016

Wnt/β-Catenin Signaling Activates Expression of the Bone-Related Transcription Factor RUNX2 in Select Human Osteosarcoma Cell Types

artículo científico publicado en 2017

X-inactivation reveals epigenetic anomalies in most hESC but identifies sublines that initiate as expected

artículo científico publicado en 2008

hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3.

artículo científico publicado en 2014

miR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cells

artículo científico publicado en 2012

miRNA signatures associate with pathogenesis and progression of osteosarcoma

artículo científico publicado en 2012

microRNA-mediated survivin control of pluripotency

artículo científico publicado en 2015

p53 checkpoint ablation exacerbates the phenotype of Hinfp dependent histone H4 deficiency

artículo científico publicado en 2015

p68 (Ddx5) interacts with Runx2 and regulates osteoblast differentiation

artículo científico publicado en 2008

tsRNA signatures in cancer

artículo científico publicado en 2017

α(V)β(6) integrin expression is induced in the POET and Pten(pc-/-) mouse models of prostatic inflammation and prostatic adenocarcinoma.

artículo científico publicado en 2012

Runx2/DICER/miRNA Pathway in Regulating Osteogenesis

artículo científico publicado en 2016

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