Lista de obras -

93rd Annual Meeting of the American Association for Cancer Research, San Francisco, CA, USA, 6-10 April 2002

artículo científico publicado en 2002

A Soft Microenvironment Protects from Failure of Midbody Abscission and Multinucleation Downstream of the EMT-Promoting Transcription Factor Snail

artículo científico publicado en 2018

Activation of PI3K/Akt/mTOR signaling in the tumor stroma drives endocrine therapy-dependent breast tumor regression

artículo científico publicado en 2015

Alterations in the Immune Cell Composition in Premalignant Breast Tissue that Precede Breast Cancer Development

artículo científico publicado en 2017

Association between mammographic breast density and histologic features of benign breast disease

artículo científico publicado en 2017

Association between mammographic density and age-related lobular involution of the breast.

artículo científico publicado en 2010

Benign Breast Disease and the Risk of Subsequent Breast Cancer in African American Women ⬇️

artículo científico publicado el 19 de octubre de 2012

Bioinformatics and DNA-extraction strategies to reliably detect genetic variants from FFPE breast tissue samples

scientific article published on 02 September 2019

Breast Cancer Risk and Progressive Histology in Serial Benign Biopsies

artículo científico publicado en 2017

Breast Cancer Risk and Use of Non-steroidal Anti-inflammatory Agents After a Benign Breast Biopsy

artículo científico publicado en 2020

Breast cancer risk by the extent and type of atypical hyperplasia

artículo científico publicado en 2016

CD56+ immune cell infiltration and MICA are decreased in breast lobules with fibrocystic changes.

artículo científico publicado en 2017

Cancer. Respect thy neighbor!

artículo científico publicado en 2004

Change in cell shape is required for matrix metalloproteinase-induced epithelial-mesenchymal transition of mammary epithelial cells

artículo científico publicado en 2008

Clinical characteristics of breast cancers in African-American women with benign breast disease: a comparison to the surveillance, epidemiology, and end results program

artículo científico publicado en 2014

Clinicopathologic features of breast cancers that develop in women with previous benign breast disease.

artículo científico publicado en 2015

Combinatorial protein engineering of proteolytically resistant mesotrypsin inhibitors as candidates for cancer therapy

artículo científico publicado en 2016

Complex fibroadenoma and breast cancer risk: a Mayo Clinic Benign Breast Disease Cohort Study

artículo científico publicado en 2015

Cytotoxic T cell depletion with increasing epithelial abnormality in women with benign breast disease

scientific article published on 13 January 2020

Delivering the message: epimorphin and mammary epithelial morphogenesis

artículo científico publicado en 2003

EGFR as a prognostic biomarker and therapeutic target in ovarian cancer: evaluation of patient cohort and literature review

artículo científico publicado en 2017

ERβ expression and breast cancer risk prediction for women with atypias

artículo científico publicado en 2015

Effective Targeting of Estrogen Receptor-Negative Breast Cancers with the Protein Kinase D Inhibitor CRT0066101.

artículo científico publicado en 2015

Enhanced antitumor immunity via endocrine therapy prevents mammary tumor relapse and increases immune checkpoint blockade sensitivity

scientific article published on 02 December 2020

Epimorphin Is a Novel Regulator of the Progesterone Receptor Isoform-A ⬇️

artículo científico publicado el 18 de julio de 2013

Epimorphin acts to induce hair follicle anagen in C57BL/6 mice

artículo científico publicado en 2003

Epithelial-mesenchymal transition: general principles and pathological relevance with special emphasis on the role of matrix metalloproteinases

artículo científico publicado en 2012

Estrogen receptor expression in atypical hyperplasia: lack of association with breast cancer

artículo científico publicado en 2011

Evaluation of 2 breast cancer risk models in a benign breast disease cohort

artículo científico publicado en 2018

Extent of atypical hyperplasia stratifies breast cancer risk in 2 independent cohorts of women

scientific article published on 28 June 2016

Extracellular localization of epimorphin/syntaxin-2.

artículo científico publicado en 2007

Fibrosis and cancer: do myofibroblasts come also from epithelial cells via EMT?

artículo científico publicado en 2007

Flat epithelial atypia and risk of breast cancer: A Mayo cohort study

artículo científico publicado en 2015

Gene signature model for breast cancer risk prediction for women with sclerosing adenosis.

artículo científico publicado en 2015

Histologic findings in normal breast tissues: comparison to reduction mammaplasty and benign breast disease tissues

artículo científico publicado en 2011

Homology with vesicle fusion mediator syntaxin-1a predicts determinants of epimorphin/syntaxin-2 function in mammary epithelial morphogenesis

artículo científico publicado en 2009

Hyaline fibrous involution of breast lobules: a histologic finding associated with germline BRCA mutation

artículo científico publicado en 2019

Identifying the Stroma as a Critical Player in Radiation-Induced Mammary Tumor Development ⬇️

artículo científico publicado el 17 de mayo de 2011

Immune Responses and Risk of Triple Negative Breast Cancer: Implications for Higher Rates among African American women

artículo científico publicado en 2020

Immune cell quantitation in normal breast tissue lobules with and without lobulitis.

artículo científico publicado en 2014

Immune promotion of epithelial-mesenchymal transition and generation of breast cancer stem cells.

artículo científico publicado en 2010

Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells

artículo científico publicado en 2009

Involvement of hnRNP A1 in the matrix metalloprotease-3-dependent regulation of Rac1 pre-mRNA splicing.

scientific article published on July 2012

Ki-67 expression in sclerosing adenosis and adjacent normal breast terminal ductal lobular units: a nested case-control study from the Mayo Benign Breast Disease Cohort

artículo científico publicado en 2015

Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia

artículo científico publicado en 2008

Lobular involution: localized phenomenon or field effect?

artículo científico publicado en 2008

MYC Is a Crucial Mediator of TGFβ-Induced Invasion in Basal Breast Cancer

artículo científico publicado en 2016

MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits

artículo científico publicado en 2012

Macrophagic "crown-like structures" are associated with an increased risk of breast cancer in benign breast disease

artículo científico publicado en 2017

Malignant mammary cells acquire independence from extracellular context for regulation of estrogen receptor alpha

artículo científico publicado en 2004

Mammary involution and breast cancer risk: transgenic models and clinical studies

scientific article published on 30 April 2009

Mammographic breast density and risk of breast cancer in women with atypical hyperplasia: an observational cohort study from the Mayo Clinic Benign Breast Disease (BBD) cohort

artículo científico publicado en 2017

Matrix Metalloproteinase-10 (MMP-10) Interaction with Tissue Inhibitors of Metalloproteinases TIMP-1 and TIMP-2: BINDING STUDIES AND CRYSTAL STRUCTURE

artículo científico publicado en 2012

Matrix metalloproteinase-induced genomic instability

artículo científico publicado en 2005

Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2.

artículo científico publicado en 2006

Mechanisms of disease: epithelial-mesenchymal transition--does cellular plasticity fuel neoplastic progression?

artículo científico publicado en 2008

Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109

artículo científico publicado en 2009

Microenvironmental Influences that Drive Progression from Benign Breast Disease to Invasive Breast Cancer ⬇️

artículo científico publicado el 16 de diciembre de 2010

Model for Predicting Breast Cancer Risk in Women With Atypical Hyperplasia

artículo científico publicado en 2018

Model for individualized prediction of breast cancer risk after a benign breast biopsy

artículo científico publicado en 2015

NF-kappaB links oestrogen receptor signalling and EMT

artículo científico publicado en 2007

NanoString-based breast cancer risk prediction for women with sclerosing adenosis

artículo científico

Natural history of age-related lobular involution and impact on breast cancer risk

artículo científico publicado en 2016

Non-classical export of epimorphin and its adhesion to alphav-integrin in regulation of epithelial morphogenesis

artículo científico publicado en 2007

Novel breast tissue feature strongly associated with risk of breast cancer

artículo científico publicado en 2009

PRSS3/Mesotrypsin Is a Therapeutic Target for Metastatic Prostate Cancer ⬇️

artículo científico publicado el 1 de diciembre de 2012

Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells

artículo científico publicado en 2004

Postlactational involution biomarkers plasminogen and phospho-STAT3 are linked with active age-related lobular involution.

artículo científico publicado en 2017

Proliferation and polarity in breast cancer: untying the Gordian knot

artículo científico publicado en 2005

Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia

artículo científico publicado en 2015

Pseudoangiomatous stromal hyperplasia and breast cancer risk

artículo científico publicado en 2010

ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-kB-dependent activation of Snail

artículo científico publicado en 2014

Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion

artículo científico publicado en 2015

Regulation of mechanical stress by mammary epithelial tissue structure controls breast cancer cell invasion ⬇️

artículo científico publicado el 1 de abril de 2013

Sclerosing adenosis and risk of breast cancer.

artículo científico publicado en 2014

Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancers

artículo científico publicado en 2015

Single proteins might have dual but related functions in intracellular and extracellular microenvironments

scientific article published on 04 February 2009

Snail1, Snail2, and E47 promote mammary epithelial branching morphogenesis ⬇️

artículo científico publicado el 24 de mayo de 2011

TGFβ/TNFα-Mediated Epithelial–Mesenchymal Transition Generates Breast Cancer Stem Cells with a Claudin-Low Phenotype ⬇️

artículo científico publicado el 9 de mayo de 2011

The 19-amino acid insertion in the tumor-associated splice isoform Rac1b confers specific binding to p120 catenin

artículo científico publicado en 2010

The Microbiome of Aseptically Collected Human Breast Tissue in Benign and Malignant Disease

artículo científico publicado en 2016

The P 2 ′ residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity

artículo científico publicado en 2011

The organizing principle: microenvironmental influences in the normal and malignant breast

artículo científico publicado en 2002

Therapeutic Potential of Matrix Metalloproteinase Inhibition in Breast Cancer

artículo científico publicado en 2017

Tissue Stiffness and Hypoxia Modulate the Integrin-Linked Kinase ILK to Control Breast Cancer Stem-like Cells

artículo científico publicado en 2016

Tissue composition of mammographically dense and non-dense breast tissue ⬇️

artículo científico publicado el 30 de agosto de 2011

Tumor cell-derived MMP3 orchestrates Rac1b and tissue alterations that promote pancreatic adenocarcinoma

artículo científico publicado en 2014

Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer

artículo científico publicado en 2014

Understanding the premalignant potential of atypical hyperplasia through its natural history: a longitudinal cohort study

artículo científico publicado en 2014

p16(INK4a) expression and breast cancer risk in women with atypical hyperplasia

artículo científico publicado en 2011

Lista de obras de

93rd Annual Meeting of the American Association for Cancer Research, San Francisco, CA, USA, 6-10 April 2002

A Soft Microenvironment Protects from Failure of Midbody Abscission and Multinucleation Downstream of the EMT-Promoting Transcription Factor Snail

Activation of PI3K/Akt/mTOR signaling in the tumor stroma drives endocrine therapy-dependent breast tumor regression

Alterations in the Immune Cell Composition in Premalignant Breast Tissue that Precede Breast Cancer Development

Association between mammographic breast density and histologic features of benign breast disease

Association between mammographic density and age-related lobular involution of the breast.

Benign Breast Disease and the Risk of Subsequent Breast Cancer in African American Women ⬇️

Bioinformatics and DNA-extraction strategies to reliably detect genetic variants from FFPE breast tissue samples

Breast Cancer Risk and Progressive Histology in Serial Benign Biopsies

Breast Cancer Risk and Use of Non-steroidal Anti-inflammatory Agents After a Benign Breast Biopsy

Breast cancer risk by the extent and type of atypical hyperplasia

CD56+ immune cell infiltration and MICA are decreased in breast lobules with fibrocystic changes.

Cancer. Respect thy neighbor!

Change in cell shape is required for matrix metalloproteinase-induced epithelial-mesenchymal transition of mammary epithelial cells

Clinical characteristics of breast cancers in African-American women with benign breast disease: a comparison to the surveillance, epidemiology, and end results program

Clinicopathologic features of breast cancers that develop in women with previous benign breast disease.

Combinatorial protein engineering of proteolytically resistant mesotrypsin inhibitors as candidates for cancer therapy

Complex fibroadenoma and breast cancer risk: a Mayo Clinic Benign Breast Disease Cohort Study

Cytotoxic T cell depletion with increasing epithelial abnormality in women with benign breast disease

Delivering the message: epimorphin and mammary epithelial morphogenesis

EGFR as a prognostic biomarker and therapeutic target in ovarian cancer: evaluation of patient cohort and literature review

ERβ expression and breast cancer risk prediction for women with atypias

Effective Targeting of Estrogen Receptor-Negative Breast Cancers with the Protein Kinase D Inhibitor CRT0066101.

Enhanced antitumor immunity via endocrine therapy prevents mammary tumor relapse and increases immune checkpoint blockade sensitivity

Epimorphin Is a Novel Regulator of the Progesterone Receptor Isoform-A ⬇️

Epimorphin acts to induce hair follicle anagen in C57BL/6 mice

Epithelial-mesenchymal transition: general principles and pathological relevance with special emphasis on the role of matrix metalloproteinases

Estrogen receptor expression in atypical hyperplasia: lack of association with breast cancer

Evaluation of 2 breast cancer risk models in a benign breast disease cohort

Extent of atypical hyperplasia stratifies breast cancer risk in 2 independent cohorts of women

Extracellular localization of epimorphin/syntaxin-2.

Fibrosis and cancer: do myofibroblasts come also from epithelial cells via EMT?

Flat epithelial atypia and risk of breast cancer: A Mayo cohort study

Gene signature model for breast cancer risk prediction for women with sclerosing adenosis.

Histologic findings in normal breast tissues: comparison to reduction mammaplasty and benign breast disease tissues

Homology with vesicle fusion mediator syntaxin-1a predicts determinants of epimorphin/syntaxin-2 function in mammary epithelial morphogenesis

Hyaline fibrous involution of breast lobules: a histologic finding associated with germline BRCA mutation

Identifying the Stroma as a Critical Player in Radiation-Induced Mammary Tumor Development ⬇️

Immune Responses and Risk of Triple Negative Breast Cancer: Implications for Higher Rates among African American women

Immune cell quantitation in normal breast tissue lobules with and without lobulitis.

Immune promotion of epithelial-mesenchymal transition and generation of breast cancer stem cells.

Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells

Involvement of hnRNP A1 in the matrix metalloprotease-3-dependent regulation of Rac1 pre-mRNA splicing.

Ki-67 expression in sclerosing adenosis and adjacent normal breast terminal ductal lobular units: a nested case-control study from the Mayo Benign Breast Disease Cohort

Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia

Lobular involution: localized phenomenon or field effect?

MYC Is a Crucial Mediator of TGFβ-Induced Invasion in Basal Breast Cancer

MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits

Macrophagic "crown-like structures" are associated with an increased risk of breast cancer in benign breast disease

Malignant mammary cells acquire independence from extracellular context for regulation of estrogen receptor alpha

Mammary involution and breast cancer risk: transgenic models and clinical studies

Mammographic breast density and risk of breast cancer in women with atypical hyperplasia: an observational cohort study from the Mayo Clinic Benign Breast Disease (BBD) cohort

Matrix Metalloproteinase-10 (MMP-10) Interaction with Tissue Inhibitors of Metalloproteinases TIMP-1 and TIMP-2: BINDING STUDIES AND CRYSTAL STRUCTURE

Matrix metalloproteinase-induced genomic instability

Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2.

Mechanisms of disease: epithelial-mesenchymal transition--does cellular plasticity fuel neoplastic progression?

Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109

Microenvironmental Influences that Drive Progression from Benign Breast Disease to Invasive Breast Cancer ⬇️

Model for Predicting Breast Cancer Risk in Women With Atypical Hyperplasia

Model for individualized prediction of breast cancer risk after a benign breast biopsy

NF-kappaB links oestrogen receptor signalling and EMT

NanoString-based breast cancer risk prediction for women with sclerosing adenosis

Natural history of age-related lobular involution and impact on breast cancer risk

Non-classical export of epimorphin and its adhesion to alphav-integrin in regulation of epithelial morphogenesis

Novel breast tissue feature strongly associated with risk of breast cancer

PRSS3/Mesotrypsin Is a Therapeutic Target for Metastatic Prostate Cancer ⬇️

Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells

Postlactational involution biomarkers plasminogen and phospho-STAT3 are linked with active age-related lobular involution.

Proliferation and polarity in breast cancer: untying the Gordian knot

Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia

Pseudoangiomatous stromal hyperplasia and breast cancer risk

ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-kB-dependent activation of Snail

Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion

Regulation of mechanical stress by mammary epithelial tissue structure controls breast cancer cell invasion ⬇️

Sclerosing adenosis and risk of breast cancer.

Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancers

Single proteins might have dual but related functions in intracellular and extracellular microenvironments

Snail1, Snail2, and E47 promote mammary epithelial branching morphogenesis ⬇️

TGFβ/TNFα-Mediated Epithelial–Mesenchymal Transition Generates Breast Cancer Stem Cells with a Claudin-Low Phenotype ⬇️