Lista de obras -

A Missense Point Mutation in Nerve Growth Factor (NGFR100W) Results in Selective Peripheral Sensory Neuropathy

artículo científico publicado en 2020

A phase 3 trial of IV immunoglobulin for Alzheimer disease

artículo científico

Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy

artículo científico publicado en 2017

Assessing Neuronal and Astrocyte Derived Exosomes From Individuals With Mild Traumatic Brain Injury for Markers of Neurodegeneration and Cytotoxic Activity

scientific article published on 02 October 2019

Blood-based biomarkers in Alzheimer disease: Current state of the science and a novel collaborative paradigm for advancing from discovery to clinic

artículo científico publicado en 2016

Brain cell type-specific enhancer-promoter interactome maps and disease-risk association

scientific article published on 14 November 2019

Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology

artículo científico publicado en 2017

CSF biomarker variability in the Alzheimer's Association quality control program

artículo científico publicado en 2013

Caspase Activation in the Alzheimer's Disease Brain: Tortuous and Torturous.

artículo científico publicado en 2002

Caspase-9 activation and caspase cleavage of tau in the Alzheimer's disease brain

artículo científico publicado en 2002

Caspase-cleaved tau accumulation in neurodegenerative diseases associated with tau and alpha-synuclein pathology.

artículo científico publicado en 2005

Cathepsin B in neurodegeneration of Alzheimer's disease, traumatic brain injury, and related brain disorders

scientific article published on 16 April 2020

Characterization of ATP alternations in an Alzheimer's disease transgenic mouse model

artículo científico publicado en 2015

Clinical-Neuropathological Correlations of Alzheimer's Disease and Related Dementias in Latino Volunteers

artículo científico publicado en 2018

Combined Active Humoral and Cellular Immunization Approaches for the Treatment of Synucleinopathies

artículo científico publicado en 2017

Comparing biological markers of Alzheimer's disease across blood fraction and platforms: Comparing apples to oranges

artículo científico publicado en 2016

Complement protein levels in plasma astrocyte-derived exosomes are abnormal in conversion from mild cognitive impairment to Alzheimer's disease dementia

article

Correction to: Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology

artículo científico publicado en 2020

Corticotropin-Releasing Factor Receptor-1 Antagonism Reduces Oxidative Damage in an Alzheimer’s Disease Transgenic Mouse Model

artículo científico publicado en 2015

Corticotropin-releasing factor receptor-1 antagonism mitigates beta amyloid pathology and cognitive and synaptic deficits in a mouse model of Alzheimer's disease

artículo científico publicado en 2015

Corticotropin-releasing factor receptor-1 modulates biomarkers of DNA oxidation in Alzheimer's disease mice.

artículo científico publicado en 2017

Corticotropin-releasing factor receptors differentially regulate stress-induced tau phosphorylation.

artículo científico publicado en 2007

Differential Effects of Meal Challenges on Cognition, Metabolism, and Biomarkers for Apolipoprotein E ɛ4 Carriers and Adults with Mild Cognitive Impairment

artículo científico publicado en 2015

Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy

artículo científico publicado en 2017

Differential preservation of AMPA receptor subunits in the hippocampi of Alzheimer's disease patients according to Braak stage

artículo científico publicado en 2004

Dysregulation of Exosome Cargo by Mutant Tau Expressed in Human-Induced Pluripotent Stem Cell (iPSC) Neurons Revealed by Proteomics Analyses

scientific article published on 15 April 2020

Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy

artículo científico publicado en 2020

Early neuronal accumulation of DNA double strand breaks in Alzheimer's disease

scholarly article by Niraj M Shanbhag et al published 17 May 2019 in Acta neuropathologica communications

Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson's disease/dementia with Lewy bodies

artículo científico publicado en 2018

Effects of single and combined immunotherapy approach targeting amyloid β protein and α-synuclein in a dementia with Lewy bodies-like model

scientific article published on 01 August 2019

Extracellular Vesicles Isolated from Familial Alzheimer's Disease Neuronal Cultures Induce Aberrant Tau Phosphorylation in the Wild-Type Mouse Brain

artículo científico publicado en 2019

Functional Impact of Corticotropin-Releasing Factor Exposure on Tau Phosphorylation and Axon Transport

artículo científico publicado en 2016

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD

scientific article published on 09 February 2019

Genome-wide association study and functional validation implicates JADE1 in tauopathy

artículo científico publicado en 2021

Growth Hormone-Releasing Hormone Administration in Mild Cognitive Impairment and Its Impact on Neuronal Exosome Biomarkers of Dementia

artículo científico publicado en 2018

Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research

artículo científico publicado en 2015

Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation

article

Impact of CRFR1 Ablation on Amyloid-β Production and Accumulation in a Mouse Model of Alzheimer's Disease

artículo científico publicado en 2015

Implications for treatment: GABAA receptors in aging, Down syndrome and Alzheimer’s disease ⬇️

artículo científico publicado el 28 de marzo de 2011

Increased Vulnerability of the Hippocampus in Transgenic Mice Overexpressing APP and Triple Repeat Tau.

artículo científico publicado en 2018

Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor

artículo científico publicado en 2015

Integrating Gene and Protein Expression Reveals Perturbed Functional Networks in Alzheimer's Disease

artículo científico publicado en 2019

LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies

artículo científico publicado en 2020

Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzheimer's disease.

artículo científico publicado en 2018

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report.

artículo científico publicado en 2019

Lipopolysaccharide-induced tau phosphorylation and kinase activity--modulation, but not mediation, by corticotropin-releasing factor receptors

artículo científico publicado en 2011

Long-Term Electrophysiological and Behavioral Analysis on the Improvement of Visual Working Memory Load, Training Gains, and Transfer Benefits

artículo científico publicado en 2014

Longitudinal plasma amyloid beta as a biomarker of Alzheimer's disease

artículo científico publicado en 2012

Mutant Presenilin 1 Dysregulates Exosomal Proteome Cargo Produced by Human-Induced Pluripotent Stem Cell Neurons

artículo científico publicado en 2021

Mutant three-repeat tau expression initiates retinal ganglion cell death through Caspase-2

artículo científico publicado en 2021

Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models

artículo científico publicado en 2020

Neuronal Exosome-Derived Human Tau is Toxic to Recipient Mouse Neurons in vivo

artículo científico publicado en 2019

NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism

artículo científico publicado en 2017

Noncanonical transnitrosylation network contributes to synapse loss in Alzheimer's disease

artículo científico publicado en 2020

Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation

artículo científico publicado en 2017

Perspectives on ethnic and racial disparities in Alzheimer's disease and related dementias: Update and areas of immediate need

artículo científico publicado en 2018

Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606.

artículo científico publicado en 2017

Plasma Neurofilament Light and Alzheimer's Disease Biomarkers in Down Syndrome: Results from the Down Syndrome Biomarker Initiative (DSBI)

artículo científico publicado en 2019

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

artículo científico publicado en 2018

Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profile

artículo científico publicado en 2016

Reducing Endogenous α-Synuclein Mitigates the Degeneration of Selective Neuronal Populations in an Alzheimer's Disease Transgenic Mouse Model

artículo científico publicado en 2016

Reflections on the Utility of the Retina as a Biomarker for Alzheimer's Disease: A Literature Review

scientific article published on 12 December 2019

Role of Alterations in Protein Kinase p38γ in the Pathogenesis of the Synaptic Pathology in Dementia With Lewy Bodies and α-Synuclein Transgenic Models

artículo científico publicado en 2020

Safety and Efficacy of Edonerpic Maleate for Patients With Mild to Moderate Alzheimer Disease: A Phase 2 Randomized Clinical Trial

scientific article published on 08 July 2019

Safety, Efficacy, and Feasibility of Intranasal Insulin for the Treatment of Mild Cognitive Impairment and Alzheimer Disease Dementia: A Randomized Clinical Trial

scientific article published on 22 June 2020

Selective targeting of 3 repeat Tau with brain penetrating single chain antibodies for the treatment of neurodegenerative disorders

scientific article published on 14 June 2018

Subregional analysis of GABA(A) receptor subunit mRNAs in the hippocampus of older persons with and without cognitive impairment

scientific article published on 01 September 2004

Synuclein impairs trafficking and signaling of BDNF in a mouse model of Parkinson's disease

artículo científico publicado en 2017

Systemic peptide mediated delivery of an siRNA targeting α-syn in the CNS ameliorates the neurodegenerative process in a transgenic model of Lewy body disease

scientific article published on 05 March 2019

T-complex protein 1-ring complex enhances retrograde axonal transport by modulating tau phosphorylation

scientific article published on 12 September 2018

Targeted Mutation (R100W) of the Gene Encoding NGF Leads to Deficits in the Peripheral Sensory Nervous System

article

The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers

artículo científico publicado en 2011

The GSM BPN-15606 as a Potential Candidate for Preventative Therapy in Alzheimer's Disease

artículo científico publicado en 2020

The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer's disease

scientific article published on 02 September 2020

Transcriptome analyses reveal tau isoform-driven changes in transposable element and gene expression

artículo científico publicado en 2021

Transcriptomic analysis of brain tissues identifies a role for CCAAT enhancer binding protein β in HIV-associated neurocognitive disorder

scientific article published on 11 April 2020

Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease

scientific article published on 18 June 2020

miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer's Patients

scientific article published on 26 November 2019

Lista de obras de

A Missense Point Mutation in Nerve Growth Factor (NGFR100W) Results in Selective Peripheral Sensory Neuropathy

A phase 3 trial of IV immunoglobulin for Alzheimer disease

Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy

Assessing Neuronal and Astrocyte Derived Exosomes From Individuals With Mild Traumatic Brain Injury for Markers of Neurodegeneration and Cytotoxic Activity

Blood-based biomarkers in Alzheimer disease: Current state of the science and a novel collaborative paradigm for advancing from discovery to clinic

Brain cell type-specific enhancer-promoter interactome maps and disease-risk association

Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology

CSF biomarker variability in the Alzheimer's Association quality control program

Caspase Activation in the Alzheimer's Disease Brain: Tortuous and Torturous.

Caspase-9 activation and caspase cleavage of tau in the Alzheimer's disease brain

Caspase-cleaved tau accumulation in neurodegenerative diseases associated with tau and alpha-synuclein pathology.

Cathepsin B in neurodegeneration of Alzheimer's disease, traumatic brain injury, and related brain disorders

Characterization of ATP alternations in an Alzheimer's disease transgenic mouse model

Clinical-Neuropathological Correlations of Alzheimer's Disease and Related Dementias in Latino Volunteers

Combined Active Humoral and Cellular Immunization Approaches for the Treatment of Synucleinopathies

Comparing biological markers of Alzheimer's disease across blood fraction and platforms: Comparing apples to oranges

Complement protein levels in plasma astrocyte-derived exosomes are abnormal in conversion from mild cognitive impairment to Alzheimer's disease dementia

Correction to: Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology

Corticotropin-Releasing Factor Receptor-1 Antagonism Reduces Oxidative Damage in an Alzheimer’s Disease Transgenic Mouse Model

Corticotropin-releasing factor receptor-1 antagonism mitigates beta amyloid pathology and cognitive and synaptic deficits in a mouse model of Alzheimer's disease

Corticotropin-releasing factor receptor-1 modulates biomarkers of DNA oxidation in Alzheimer's disease mice.

Corticotropin-releasing factor receptors differentially regulate stress-induced tau phosphorylation.

Differential Effects of Meal Challenges on Cognition, Metabolism, and Biomarkers for Apolipoprotein E ɛ4 Carriers and Adults with Mild Cognitive Impairment

Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy

Differential preservation of AMPA receptor subunits in the hippocampi of Alzheimer's disease patients according to Braak stage

Dysregulation of Exosome Cargo by Mutant Tau Expressed in Human-Induced Pluripotent Stem Cell (iPSC) Neurons Revealed by Proteomics Analyses

Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy

Early neuronal accumulation of DNA double strand breaks in Alzheimer's disease

Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson's disease/dementia with Lewy bodies

Effects of single and combined immunotherapy approach targeting amyloid β protein and α-synuclein in a dementia with Lewy bodies-like model

Extracellular Vesicles Isolated from Familial Alzheimer's Disease Neuronal Cultures Induce Aberrant Tau Phosphorylation in the Wild-Type Mouse Brain

Functional Impact of Corticotropin-Releasing Factor Exposure on Tau Phosphorylation and Axon Transport

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD

Genome-wide association study and functional validation implicates JADE1 in tauopathy

Growth Hormone-Releasing Hormone Administration in Mild Cognitive Impairment and Its Impact on Neuronal Exosome Biomarkers of Dementia

Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research

Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation

Impact of CRFR1 Ablation on Amyloid-β Production and Accumulation in a Mouse Model of Alzheimer's Disease

Implications for treatment: GABAA receptors in aging, Down syndrome and Alzheimer’s disease ⬇️

Increased Vulnerability of the Hippocampus in Transgenic Mice Overexpressing APP and Triple Repeat Tau.

Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor

Integrating Gene and Protein Expression Reveals Perturbed Functional Networks in Alzheimer's Disease

LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies

Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzheimer's disease.

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report.

Lipopolysaccharide-induced tau phosphorylation and kinase activity--modulation, but not mediation, by corticotropin-releasing factor receptors

Long-Term Electrophysiological and Behavioral Analysis on the Improvement of Visual Working Memory Load, Training Gains, and Transfer Benefits

Longitudinal plasma amyloid beta as a biomarker of Alzheimer's disease

Mutant Presenilin 1 Dysregulates Exosomal Proteome Cargo Produced by Human-Induced Pluripotent Stem Cell Neurons

Mutant three-repeat tau expression initiates retinal ganglion cell death through Caspase-2

Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models

Neuronal Exosome-Derived Human Tau is Toxic to Recipient Mouse Neurons in vivo

NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism

Noncanonical transnitrosylation network contributes to synapse loss in Alzheimer's disease

Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation

Perspectives on ethnic and racial disparities in Alzheimer's disease and related dementias: Update and areas of immediate need

Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606.

Plasma Neurofilament Light and Alzheimer's Disease Biomarkers in Down Syndrome: Results from the Down Syndrome Biomarker Initiative (DSBI)

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profile

Reducing Endogenous α-Synuclein Mitigates the Degeneration of Selective Neuronal Populations in an Alzheimer's Disease Transgenic Mouse Model

Reflections on the Utility of the Retina as a Biomarker for Alzheimer's Disease: A Literature Review

Role of Alterations in Protein Kinase p38γ in the Pathogenesis of the Synaptic Pathology in Dementia With Lewy Bodies and α-Synuclein Transgenic Models

Safety and Efficacy of Edonerpic Maleate for Patients With Mild to Moderate Alzheimer Disease: A Phase 2 Randomized Clinical Trial

Safety, Efficacy, and Feasibility of Intranasal Insulin for the Treatment of Mild Cognitive Impairment and Alzheimer Disease Dementia: A Randomized Clinical Trial

Selective targeting of 3 repeat Tau with brain penetrating single chain antibodies for the treatment of neurodegenerative disorders

Subregional analysis of GABA(A) receptor subunit mRNAs in the hippocampus of older persons with and without cognitive impairment

Synuclein impairs trafficking and signaling of BDNF in a mouse model of Parkinson's disease

Systemic peptide mediated delivery of an siRNA targeting α-syn in the CNS ameliorates the neurodegenerative process in a transgenic model of Lewy body disease

T-complex protein 1-ring complex enhances retrograde axonal transport by modulating tau phosphorylation

Targeted Mutation (R100W) of the Gene Encoding NGF Leads to Deficits in the Peripheral Sensory Nervous System

The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers

The GSM BPN-15606 as a Potential Candidate for Preventative Therapy in Alzheimer's Disease

The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer's disease

Transcriptome analyses reveal tau isoform-driven changes in transposable element and gene expression

Transcriptomic analysis of brain tissues identifies a role for CCAAT enhancer binding protein β in HIV-associated neurocognitive disorder

Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease

miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer's Patients