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2'-Fluoro RNA shows increased Watson-Crick H-bonding strength and stacking relative to RNA: evidence from NMR and thermodynamic data

artículo científico publicado en 2012

2-Methoxypyridine as Thymidine Mimic in Watson-Crick Base Pairs of DNA and PNA: Synthesis, Thermal Stability and NMR Structural Studies.

artículo científico

A Single Amide Linkage in the Passenger Strand Suppresses Its Activity and Enhances Guide Strand Targeting of siRNAs.

artículo científico publicado en 2018

Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs

artículo científico publicado en 2017

Amide-Modified RNA: Using Protein Backbone to Modulate Function of Short Interfering RNAs

artículo científico publicado en 2020

Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs

artículo científico publicado en 2014

Amides as excellent mimics of phosphate linkages in RNA

artículo científico publicado en 2011

Artificially created nucleic acids and peptides/proteins in chemical biology

artículo científico publicado en 2013

Asymmetric synthesis of trans-3,4-dialkyl-gamma-butyrolactones via an acyl-Claisen and iodolactonization route

scientific article published on 01 July 2005

Calorimetry of Nucleic Acids

artículo científico publicado en 2015

Concurrent Hydrogenation of Three Functional Groups Enables Synthesis of C3'-Homologated Nucleoside Amino Acids

artículo científico publicado en 2017

Correction: Triplex-forming peptide nucleic acid modified with 2-aminopyridine as a new tool for detection of A-to-I editing

artículo científico publicado en 2016

Cover Feature: Synthetic, Structural, and RNA Binding Studies on 2‐Aminopyridine‐Modified Triplex‐Forming Peptide Nucleic Acids (Chem. Eur. J. 17/2019)

artículo científico publicado en 2019

Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme

artículo científico publicado en 2007

Determination of Nucleic Acid Hydration Using Osmotic Stress

artículo científico publicado el 1 de diciembre de 2010

Discrimination against major groove adducts by Y-family polymerases of the DinB subfamily

artículo científico publicado en 2013

Effects of non-catalytic, distal amino acid residues on activity of E. coli DinB (DNA polymerase IV).

artículo científico publicado en 2012

Expanding functionality of RNA: synthesis and properties of RNA containing imidazole modified tandem G-U wobble base pairs

artículo científico publicado en 2005

FTIR Spectroscopic Studies of Oligonucleotides That Model a Triple-Helical Domain in Self-Splicing Group I Introns

artículo científico publicado el 9 de diciembre de 1997

Fluorescent 2-Aminopyridine Nucleobases for Triplex-Forming Peptide Nucleic Acids

artículo científico publicado en 2016

Hydration of short DNA, RNA and 2'-OMe oligonucleotides determined by osmotic stressing

artículo científico publicado en 2004

Identification of tau stem loop RNA stabilizers

artículo científico publicado en 2007

Improvement of sequence selectivity in triple helical recognition of RNA by phenylalanine-derived PNA.

artículo científico

Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Nonionic Modifications Better than DNA

artículo científico publicado en 2009

Monomers for preparation of amide linked RNA: Synthesis of C3'-homologated nucleoside amino acids from d-xylose

artículo científico publicado en 2010

Monomers for preparation of amide-linked RNA: asymmetric synthesis of all four nucleoside 5'-azido 3'-carboxylic acids

artículo científico publicado en 2005

Nucleobase-Modified PNA Suppresses Translation by Forming a Triple Helix with a Hairpin Structure in mRNA In Vitro and in Cells

artículo científico publicado en 2015

Nucleobase-Modified Triplex-Forming Peptide Nucleic Acids for Sequence-Specific Recognition of Double-Stranded RNA

artículo científico publicado en 2020

Oligoribonucleotide analogues containing a mixed backbone of phosphodiester and formacetal internucleoside linkages, together with vicinal 2'-O-methyl groups

scientific article published on 01 March 2007

PNA containing isocytidine nucleobase: synthesis and recognition of double helical RNA.

artículo científico publicado en 2011

Peptide nucleic acid probe for protein affinity purification based on biotin-streptavidin interaction and peptide nucleic acid strand hybridization

artículo científico

RNA-Synthesis Using the H-Phosphonate Approach and an Improved Protecting Group Strategy

scholarly article

Recent advances in chemical modification of Peptide nucleic acids

artículo científico publicado en 2012

Recognition of double-stranded RNA by guanidine-modified peptide nucleic acids

artículo científico publicado en 2011

Sequence selective recognition of double-stranded RNA at physiologically relevant conditions using PNA-peptide conjugates

artículo científico publicado en 2013

Sequence selective recognition of double-stranded RNA using triple helix-forming peptide nucleic acids

artículo científico publicado en 2014

Sequence-selective recognition of double-stranded RNA and enhanced cellular uptake of cationic nucleobase and backbone-modified peptide nucleic acids

artículo científico publicado en 2016

Sequence-specific recognition of structured RNA by triplex-forming peptide nucleic acids

scientific article published on 27 April 2019

Short peptide nucleic acids bind strongly to homopurine tract of double helical RNA at pH 5.5.

artículo científico

Structural Insights into Conformation Differences between DNA/TNA and RNA/TNA Chimeric Duplexes

artículo científico publicado en 2016

Synthesis and Biological Activity of Short Interfering RNAs Having Several Consecutive Amide Internucleoside Linkages

scientific article published on 17 December 2019

Synthesis and RNA-Binding Properties of Extended Nucleobases for Triplex-Forming Peptide Nucleic Acids

artículo científico publicado en 2019

Synthesis and properties of RNA analogues having amides as interuridine linkages at selected positions.

artículo científico publicado en 2003

Synthesis and properties of peptide nucleic acid labeled at the N-terminus with HiLyte Fluor 488 fluorescent dye.

artículo científico publicado en 2016

Synthesis and properties of triazole-linked RNA.

artículo científico publicado en 2011

Synthesis of Oligoribonucleotides by the H-Phosphonate Approach Using Base Labile 2′-O-Protecting Groups. V. Recent Progress in Development of the Method

article

Synthesis, biophysical studies and RNA interference activity of RNA having three consecutive amide linkages

artículo científico

Synthetic, Structural, and RNA Binding Studies on 2-Aminopyridine-Modified Triplex-Forming Peptide Nucleic Acids

scientific article published on 04 March 2019

Total Synthesis of 3‘,5‘-C-Branched Nucleosides

artículo científico publicado el 16 de octubre de 2003

Toward amide-linked RNA mimics: total synthesis of 3'-C branched uridine azido acid via an ene-iodolactonization approach

artículo científico publicado en 2003

Toward amide-modified RNA: synthesis of 3'-aminomethyl-5'-carboxy-3',5'-dideoxy nucleosides

scientific article published on 01 August 2006

Triple helical recognition of pyrimidine inversions in polypurine tracts of RNA by nucleobase-modified PNA.

artículo científico publicado en 2011

Triple-helical recognition of RNA using 2-aminopyridine-modified PNA at physiologically relevant conditions

artículo científico publicado en 2012

Triplex-Forming Peptide Nucleic Acids with Extended Backbones

artículo científico publicado en 2020

Triplex-forming PNA modified with unnatural nucleobases: the role of protonation entropy in RNA binding

artículo científico publicado en 2016

Triplex-forming peptide nucleic acid modified with 2-aminopyridine as a new tool for detection of A-to-I editing

artículo científico publicado en 2016

Triplex-forming peptide nucleic acids as emerging ligands to modulate structure and function of complex RNAs

artículo científico publicado en 2024

Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA

artículo científico publicado en 2011

Unique gene-silencing and structural properties of 2'-fluoro-modified siRNAs

artículo científico publicado en 2011

Using triple-helix-forming Peptide nucleic acids for sequence-selective recognition of double-stranded RNA.

artículo científico publicado en 2014