Filtros de búsqueda

Lista de obras de

13C NMR isotopomer analysis of anaplerotic pathways in INS-1 cells

artículo científico publicado en 2004

A Membrane-Bound Diacylglycerol Species Induces PKCϵ-Mediated Hepatic Insulin Resistance

artículo científico publicado en 2020

A Non-invasive Method to Assess Hepatic Acetyl-CoA In Vivo

artículo científico publicado en 2017

A role for mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) in the regulation of hepatic gluconeogenesis

artículo científico publicado en 2014

A β-peptide agonist of the GLP-1 receptor, a class B GPCR.

artículo científico publicado en 2013

Acetate mediates a microbiome-brain-β-cell axis to promote metabolic syndrome

scientific journal article

Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents.

artículo científico publicado en 2018

Acute inhibition of lipolysis does not affect postprandial suppression of endogenous glucose production

artículo científico publicado en 2005

Adipocyte-specific overexpression of FOXC2 prevents diet-induced increases in intramuscular fatty acyl CoA and insulin resistance

artículo científico publicado en 2005

Adipose glucocorticoid action influences whole-body metabolism via modulation of hepatic insulin action

scientific article published on 28 March 2019

Alterations in postprandial hepatic glycogen metabolism in type 2 diabetes

artículo científico publicado en 2004

Altered Brain Response to Drinking Glucose and Fructose in Obese Adolescents.

scientific article published on 05 April 2016

Altered brain mitochondrial metabolism in healthy aging as assessed by in vivo magnetic resonance spectroscopy

artículo científico publicado en 2010

Anti-inflammatory effects of oestrogen mediate the sexual dimorphic response to lipid-induced insulin resistance

scientific article published on 04 July 2019

Argininosuccinate synthetase regulates hepatic AMPK linking protein catabolism and ureagenesis to hepatic lipid metabolism

artículo científico publicado en 2016

Astroglial contribution to brain energy metabolism in humans revealed by 13C nuclear magnetic resonance spectroscopy: elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolism

artículo científico publicado en 2002

Author Correction: Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo

artículo científico publicado en 2019

Blunted suppression of acyl-ghrelin in response to fructose ingestion in obese adolescents: the role of insulin resistance

artículo científico publicado en 2015

Brain-specific carnitine palmitoyl-transferase-1c: role in CNS fatty acid metabolism, food intake, and body weight

scientific article published on 28 January 2008

CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance

artículo científico publicado en 2013

Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver

artículo científico publicado en 2005

Clinical and scientific value in the pursuit of quantification of beta cells in the pancreas by PET imaging

scientific article published on 22 August 2018

Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity

artículo científico publicado en 2007

Controlled-release mitochondrial protonophore (CRMP) reverses dyslipidemia and hepatic steatosis in dysmetabolic nonhuman primates

scientific article published on 01 October 2019

Coordinated defects in hepatic long chain fatty acid metabolism and triglyceride accumulation contribute to insulin resistance in non-human primates

artículo científico publicado en 2011

Cytosolic and mitochondrial malic enzyme isoforms differentially control insulin secretion

artículo científico publicado en 2006

Decreased VMAT2 in the pancreas of humans with type 2 diabetes mellitus measured in vivo by PET imaging

artículo científico publicado en 2018

Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo

artículo científico publicado en 2004

Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13C magnetic resonance spectroscopy

artículo científico publicado en 2013

Dissociation of Muscle Insulin Resistance from Alterations in Mitochondrial Substrate Preference

artículo científico publicado en 2020

Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease

artículo científico publicado en 2020

Effect of a sustained reduction in plasma free fatty acid concentration on intramuscular long-chain fatty Acyl-CoAs and insulin action in type 2 diabetic patients

artículo científico publicado en 2005

Effect of aging on muscle mitochondrial substrate utilization in humans

artículo científico publicado en 2015

Effects of a novel glycogen synthase kinase-3 inhibitor on insulin-stimulated glucose metabolism in Zucker diabetic fatty (fa/fa) rats

artículo científico publicado en 2002

Effects of fructose vs glucose on regional cerebral blood flow in brain regions involved with appetite and reward pathways

artículo científico publicado en 2013

Effects of pioglitazone on intramyocellular fat metabolism in patients with type 2 diabetes mellitus

artículo científico publicado en 2010

Effects of rexinoids on glucose transport and insulin-mediated signaling in skeletal muscles of diabetic (db/db) mice

artículo científico publicado en 2004

Fish oil regulates adiponectin secretion by a peroxisome proliferator-activated receptor-gamma-dependent mechanism in mice

scientific article published on 01 April 2006

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.

artículo científico publicado en 2014

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

artículo científico publicado en 2010

Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance.

artículo científico publicado en 2014

Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis

artículo científico publicado en 2020

Glycerol-3-phosphate acyltransferase 1 deficiency in ob/ob mice diminishes hepatic steatosis but does not protect against insulin resistance or obesity

artículo científico publicado en 2010

Hepatic Insulin Resistance Is Not Pathway Selective in Humans With Nonalcoholic Fatty Liver Disease

artículo científico publicado en 2020

Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes

artículo científico publicado en 2015

Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance

artículo científico publicado en 2004

Hepatic overexpression of glycerol-sn-3-phosphate acyltransferase 1 in rats causes insulin resistance

artículo científico publicado en 2007

Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart

artículo científico publicado en 2005

Hypophosphatemia promotes lower rates of muscle ATP synthesis

artículo científico publicado en 2016

In vivo imaging of endogenous pancreatic β-cell mass in healthy and type 1 diabetic subjects using 18F-fluoropropyl-dihydrotetrabenazine and PET.

artículo científico publicado en 2012

In vivo studies on the mechanism of methylene cyclopropyl acetic acid and methylene cyclopropyl glycine-induced hypoglycemia

artículo científico publicado en 2018

Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle

scientific journal article

Increased hypothalamic-pituitary-adrenal axis activity and hepatic insulin resistance in low-birth-weight rats

artículo científico publicado en 2007

Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids.

artículo científico publicado en 2015

Integrated, Step-Wise, Mass-Isotopomeric Flux Analysis of the TCA Cycle

artículo científico publicado en 2015

Investigating the roles of mitochondrial and cytosolic malic enzyme in insulin secretion

artículo científico publicado en 2009

Islet-selectivity of G-protein coupled receptor ligands evaluated for PET imaging of pancreatic β-cell mass

artículo científico publicado el 28 de julio de 2011

Leptin Mediates a Glucose-Fatty Acid Cycle to Maintain Glucose Homeostasis in Starvation

artículo científico publicado en 2017

Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis

artículo científico publicado en 2014

Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy

artículo científico publicado en 2002

Lipid metabolism and adipokine levels in fatty acid-binding protein null and transgenic mice

artículo científico publicado en 2005

Liver fatty acid binding protein is required for high rates of hepatic fatty acid oxidation but not for the action of PPARalpha in fasting mice

artículo científico publicado en 2003

Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition

artículo científico publicado en 2009

Liver‐Specific Pyruvate Dehydrogenase Complex Deficiency Upregulates Lipogenesis in Adipose Tissue and Improves Peripheral Insulin Sensitivity

artículo científico publicado el 12 de septiembre de 2010

Long term evaluation of disease progression through the quantitative magnetic resonance imaging of symptomatic knee osteoarthritis patients: correlation with clinical symptoms and radiographic changes

artículo científico publicado en 2005

Lysophosphatidic acid activates peroxisome proliferator activated receptor-γ in CHO cells that over-express glycerol 3-phosphate acyltransferase-1

artículo científico publicado en 2011

Matrix alkalinization: a novel mitochondrial signal for sustained pancreatic beta-cell activation

artículo científico publicado en 2009

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

artículo científico publicado en 2002

Mechanism for leptin's acute insulin-independent effect to reverse diabetic ketoacidosis

artículo científico publicado en 2017

Mechanisms by which a Very-Low-Calorie Diet Reverses Hyperglycemia in a Rat Model of Type 2 Diabetes

artículo científico publicado en 2017

Membrane bound diacylglycerols explain the dissociation of hepatic insulin resistance from steatosis in MTTP-/- mice

scientific article published on 09 September 2020

Metabolic control analysis of hepatic glycogen synthesis in vivo

artículo científico publicado en 2020

Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo.

artículo científico publicado en 2018

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase

artículo científico publicado en 2014

Mitochondrial GTP regulates glucose-stimulated insulin secretion

scientific journal article

Mitochondrial dysfunction contributes to impaired insulin secretion in INS-1 cells with dominant-negative mutations of HNF-1alpha and in HNF-1alpha-deficient islets.

artículo científico publicado en 2009

Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance

artículo científico publicado en 2007

Mitochondrial dysfunction in the elderly: possible role in insulin resistance

artículo científico publicado en 2003

Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs

scientific journal article

Mitochondrial phosphate transport during nutrient stimulation of INS-1E insulinoma cells.

artículo científico publicado en 2013

Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs Fatty Acid oxidation and induces cardiac hypertrophy

artículo científico publicado en 2011

N-acylphosphatidylethanolamine, a gut- derived circulating factor induced by fat ingestion, inhibits food intake.

artículo científico publicado en 2008

Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA).

artículo científico publicado en 2017

Nonacute effects of H-FABP deficiency on skeletal muscle glucose uptake in vitro

artículo científico publicado en 2004

PEPCK1 Antisense Oligonucleotide Prevents Adiposity and Impairs Hepatic Glycogen Synthesis in High-Fat Male Fed Rats

scientific article published on 01 January 2019

PET Imaging of Pancreatic Dopamine D2 and D3 Receptor Density with 11C-(+)-PHNO in Type 1 Diabetes

scientific article published on 10 October 2019

PKC-theta knockout mice are protected from fat-induced insulin resistance

artículo científico publicado en 2004

Pancreatic beta cell mass PET imaging and quantification with [11C]DTBZ and [18F]FP-(+)-DTBZ in rodent models of diabetes

scientific article published on 08 September 2010

Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism

scholarly article

Phosphoenolpyruvate cycling via mitochondrial phosphoenolpyruvate carboxykinase links anaplerosis and mitochondrial GTP with insulin secretion

artículo científico publicado en 2009

Phosphoinositide profiling in complex lipid mixtures using electrospray ionization mass spectrometry

artículo científico publicado en 2003

Plasma membrane electron transport in pancreatic β-cells is mediated in part by NQO1

artículo científico publicado el 19 de abril de 2011

Prevention of hepatic steatosis and hepatic insulin resistance by knockdown of cAMP response element-binding protein

artículo científico

Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice

scientific journal article

Propionate Increases Hepatic Pyruvate Cycling and Anaplerosis and Alters Mitochondrial Metabolism

artículo científico publicado en 2016

Publisher Correction: Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA).

artículo científico publicado en 2018

Rates of insulin secretion in INS-1 cells are enhanced by coupling to anaplerosis and Kreb’s cycle flux independent of ATP synthesis

artículo científico publicado el 7 de octubre de 2011

Re-patterning of skeletal muscle energy metabolism by fat storage-inducing transmembrane protein 2.

artículo científico publicado en 2011

Reduced intestinal lipid absorption and body weight-independent improvements in insulin sensitivity in high-fat diet-fed Park2 knockout mice.

artículo científico publicado en 2016

Regulation of gluconeogenesis by Krüppel-like factor 15

artículo científico publicado en 2007

Regulation of hepatic energy metabolism and gluconeogenesis by BAD

artículo científico publicado en 2014

Regulation of hepatic mitochondrial oxidation by glucose-alanine cycling during starvation in humans

scientific article published on 01 November 2019

Regulation of hypothalamic malonyl-CoA by central glucose and leptin.

artículo científico publicado en 2007

Reply to Constantin-Teodosiu et al.: mice with genetic PDH activation are not protected from high-fat diet-induced muscle insulin resistance

artículo científico publicado en 2015

Resistance to high-fat diet-induced obesity but exacerbated insulin resistance in mice overexpressing preadipocyte factor-1 (Pref-1): a new model of partial lipodystrophy

artículo científico publicado en 2008

Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2.

artículo científico publicado en 2006

Reversal of hypertriglyceridemia, fatty liver disease, and insulin resistance by a liver-targeted mitochondrial uncoupler

artículo científico publicado en 2013

Reversal of muscle insulin resistance by weight reduction in young, lean, insulin-resistant offspring of parents with type 2 diabetes

artículo científico publicado en 2012

Risk factors associated with the loss of cartilage volume on weight-bearing areas in knee osteoarthritis patients assessed by quantitative magnetic resonance imaging: a longitudinal study

artículo científico publicado en 2007

Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion

artículo científico publicado en 2009

Role of Gut Microbiota and Short Chain Fatty Acids in Modulating Energy Harvest and Fat Partitioning in Youth.

artículo científico publicado en 2016

Role of caspase-1 in regulation of triglyceride metabolism.

artículo científico publicado en 2013

Role of patatin-like phospholipase domain-containing 3 on lipid-induced hepatic steatosis and insulin resistance in rats

artículo científico publicado en 2013

Skeletal muscle lipid metabolism with obesity

artículo científico publicado en 2002

Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance

scientific journal article

Synthesis and evaluation of [18F]exendin (9-39) as a potential biomarker to measure pancreatic β-cell mass

artículo científico publicado en 2011

Targeting pyruvate carboxylase reduces gluconeogenesis and adiposity and improves insulin resistance

artículo científico publicado en 2013

The "obese insulin-sensitive" adolescent: importance of adiponectin and lipid partitioning

artículo científico publicado en 2005

The Contribution of Blood Lactate to Brain Energy Metabolism in Humans Measured by Dynamic 13C Nuclear Magnetic Resonance Spectroscopy

artículo científico publicado en 2010

The effects of increased acetate turnover on glucose-induced insulin secretion in lean and obese humans

scientific article published on 01 February 2019

The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes

artículo científico publicado en 2002

The role of intramyocellular lipids during hypoglycemia in patients with intensively treated type 1 diabetes

artículo científico publicado en 2005

The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome

artículo científico publicado en 2007

The role of the carbohydrate response element-binding protein in male fructose-fed rats

artículo científico publicado en 2012

UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals

artículo científico publicado en 2008

cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 2 (CRTC2) promotes glucagon clearance and hepatic amino acid catabolism to regulate glucose homeostasis.

artículo científico publicado en 2013

n-3 Fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor-alpha-dependent manner.

artículo científico publicado en 2007