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Cellular immunogenicity of novel gene immunogens in mice monitored by in vivo imaging

artículo científico publicado en 2012

Consensus HIV-1 FSU-A integrase gene variants electroporated into mice induce polyfunctional antigen-specific CD4+ and CD8+ T cells

artículo científico publicado en 2013

Consensus HIV-1 subtype A integrase and its raltegravir-resistant variants: design and characterization of the enzymatic properties.

artículo científico publicado en 2014

DNA immunization site determines the level of gene expression and the magnitude, but not the type of the induced immune response.

artículo científico publicado en 2018

Enhancement of the expression of HCV core gene does not enhance core-specific immune response in DNA immunization: advantages of the heterologous DNA prime, protein boost immunization regimen

artículo científico publicado en 2009

Evaluation of immunogen delivery by DNA immunization using non-invasive bioluminescence imaging

scientific article published on 03 July 2013

Expression of the Reverse Transcriptase Domain of Telomerase Reverse Transcriptase Induces Lytic Cellular Response in DNA-Immunized Mice and Limits Tumorigenic and Metastatic Potential of Murine Adenocarcinoma 4T1 Cells

artículo científico publicado en 2020

Fusion to Flaviviral Leader Peptide Targets HIV-1 Reverse Transcriptase for Secretion and Reduces Its Enzymatic Activity and Ability to Induce Oxidative Stress but Has No Major Effects on Its Immunogenic Performance in DNA-Immunized Mice.

artículo científico publicado en 2017

HIV-1 Reverse Transcriptase Promotes Tumor Growth and Metastasis Formation via ROS-Dependent Upregulation of Twist

artículo científico publicado en 2019

HIV-1 reverse transcriptase artificially targeted for proteasomal degradation induces a mixed Th1/Th2-type immune response

artículo científico publicado en 2008

HIV-1 reverse transcriptase targeted for proteasomal degradation as a prototype vaccine against drug-resistant HIV-1.

artículo científico publicado en 2005

Intracellular degradation and localization of NS1 of tick-borne encephalitis virus affect its protective properties

artículo científico publicado en 2017

Mutations conferring drug resistance affect eukaryotic expression of HIV type 1 reverse transcriptase.

artículo científico publicado en 2004

Nonstructural Protein 1 of Tick-Borne Encephalitis Virus Induces Oxidative Stress and Activates Antioxidant Defense by the Nrf2/ARE Pathway

artículo científico publicado en 2016

Oxidative Stress during HIV Infection: Mechanisms and Consequences

artículo científico publicado en 2016

Oxidative stress induced by HIV-1 reverse transcriptase modulates the enzyme's performance in gene immunization.

artículo científico publicado en 2013

Potent cross-reactive immune response against the wild-type and drug-resistant forms of HIV reverse transcriptase after the chimeric gene immunization

artículo científico publicado en 2010

Prokaryotic Expression, Purification and Immunogenicity in Rabbits of the Small Antigen of Hepatitis Delta Virus.

scientific article published on 20 October 2016

Signal sequences modulate the immunogenic performance of human hepatitis C virus E2 gene.

artículo científico publicado en 2006

The Immunogenicity in Mice of HCV Core Delivered as DNA Is Modulated by Its Capacity to Induce Oxidative Stress and Oxidative Stress Response

artículo científico publicado en 2019