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A DNA damage repair gene-associated signature predicts responses of patients with advanced soft-tissue sarcoma to treatment with trabectedin

artículo científico publicado en 2021

CUL4A, ERCC5, and ERCC1 as Predictive Factors for Trabectedin Efficacy in Advanced Soft Tissue Sarcomas (STS): A Spanish Group for Sarcoma Research (GEIS) Study

scientific article published on 30 April 2020

Facts and hopes in immunotherapy of soft tissue sarcomas

scientific article published on 29 June 2020

Gene expression analyses determine two different subpopulations in KIT-negative GIST-like (KNGL) patients.

artículo científico publicado en 2018

Nilotinib as Coadjuvant Treatment with Doxorubicin in Patients with Sarcomas: A Phase I Trial of the Spanish Group for Research on Sarcoma

scientific article published on 23 July 2018

Oncogenic Sox2 regulates and cooperates with VRK1 in cell cycle progression and differentiation

artículo científico publicado en 2016

Pazopanib for treatment of advanced malignant and dedifferentiated solitary fibrous tumour: a multicentre, single-arm, phase 2 trial

scientific article published on 18 December 2018

Pazopanib in the treatment of advanced solitary fibrous tumour - Authors' reply

artículo científico publicado en 2019

Prognostic Impact of let-7e MicroRNA and Its Target Genes in Localized High-Risk Intestinal GIST: A Spanish Group for Research on Sarcoma (GEIS) Study

artículo científico publicado en 2020

Trabectedin Plus Radiotherapy for Advanced Soft-Tissue Sarcoma: Experience in Forty Patients Treated at a Sarcoma Reference Center

artículo científico publicado en 2020

VRK1 and AURKB form a complex that cross inhibit their kinase activity and the phosphorylation of histone H3 in the progression of mitosis.

artículo científico publicado en 2018

VRK1 chromatin kinase phosphorylates H2AX and is required for foci formation induced by DNA damage

artículo científico publicado en 2015

Which goals should we pursue in each line of treatment for advanced soft tissue sarcoma?

artículo científico publicado en 2019