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Adenovirus-Mediated Expression of the p14 Fusion-Associated Small Transmembrane Protein Promotes Cancer Cell Fusion and Apoptosis In Vitro but Does Not Provide Therapeutic Efficacy in a Xenograft Mouse Model of Cancer

artículo científico publicado en 2016

Building immune tolerance through DNA vaccination

artículo científico publicado en 2018

Chromatin structure of adenovirus DNA throughout infection

artículo científico publicado el 23 de noviembre de 2011

Development of a novel screening platform for the identification of small molecule inhibitors of human adenovirus

artículo científico publicado en 2019

Diacylglycerol kinase zeta regulates actin cytoskeleton reorganization through dissociation of Rac1 from RhoGDI

artículo científico publicado en 2009

Expression of apolipoprotein C-III in McA-RH7777 cells enhances VLDL assembly and secretion under lipid-rich conditions

artículo científico publicado en 2010

Fusion of large polypeptides to human adenovirus type 5 capsid protein IX can compromise virion stability and DNA packaging capacity

artículo científico publicado en 2020

Gene transfer of mutant mouse cholinesterase provides high lifetime expression and reduced cocaine responses with no evident toxicity

artículo científico publicado en 2013

Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Suppresses Human Adenovirus Gene Expression and Replication

article

Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Suppresses Human Adenovirus Gene Expression and Replication

artículo científico publicado en 2019

Human adenoviral DNA association with nucleosomes containing histone variant H3.3 during the early phase of infection is not dependent on viral transcription or replication

artículo científico publicado en 2018

Human adenovirus type 5 vectors deleted of early region 1 (E1) undergo limited expression of early replicative E2 proteins and DNA replication in non-permissive cells.

artículo científico

Identification of human adenovirus replication inhibitors from a library of small molecules targeting cellular epigenetic regulators

artículo científico publicado en 2020

Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease

artículo científico publicado en 2009

Opening the window: The case for carrier and perinatal screening for spinal muscular atrophy

artículo científico publicado en 2016

Plasma butyrylcholinesterase regulates ghrelin to control aggression

artículo científico publicado en 2015

Processing-dependent trafficking of Sonic hedgehog to the regulated secretory pathway in neurons

scientific journal article

Recent Advances in Novel Antiviral Therapies against Human Adenovirus

artículo científico publicado en 2020

Regulation of Macropinocytosis by Diacylglycerol Kinase ζ

artículo científico publicado en 2015

Report on the 3rd Ottawa International Conference on Neuromuscular Biology, Disease and Therapy - September 24-26, 2015, Ottawa, Canada.

artículo científico publicado en 2016

The Ldb1 and Ldb2 transcriptional cofactors interact with the Ste20-like kinase SLK and regulate cell migration

scientific journal article

The adenovirus genome contributes to the structural stability of the virion

artículo científico publicado en 2014

The role of chromatin in adenoviral vector function

artículo científico publicado en 2013

Use of cell fusion proteins to enhance adenoviral vector efficacy as an anti-cancer therapeutic

artículo científico publicado en 2020

mTORC1 activates SREBP-2 by suppressing cholesterol trafficking to lysosomes in mammalian cells

artículo científico publicado en 2017