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2178 Drug development core facilitates institutional collaboration and translational science innovation

artículo científico publicado en 2018

<b>Physiologically-Based Pharmacokinetics of Lysosomotropic Chloroquine in Rat and Man</b>

artículo científico publicado en 2020

A microarray analysis of the temporal response of liver to methylprednisolone: a comparative analysis of two dosing regimens

artículo científico publicado en 2007

A new symbolic representation for the identification of informative genes in replicated microarray experiments

artículo científico publicado en 2010

ATLAS mPBPK: a MATLAb-based tool for modeling and Simulation of minimal Physiologically Based PharmacoKinetic models

scientific article published on 02 June 2019

Across-Species Scaling of Monoclonal Antibody Pharmacokinetics Using a Minimal PBPK Model

artículo científico publicado en 2015

Adipose Tissue Deficiency and Chronic Inflammation in Diabetic Goto-Kakizaki Rats ⬇️

artículo científico publicado el 25 de febrero de 2011

Altered methylprednisolone pharmacodynamics in healthy subjects with histamine N-methyltransferase C314T genetic polymorphism

artículo científico publicado en 2006

Altered pharmacokinetics of combined oral contraceptives in obesity - multistudy assessment

artículo científico publicado en 2019

Application of scaling factors in simultaneous modeling of microarray data from diverse chips

artículo científico publicado en 2007

Applications of minimal physiologically-based pharmacokinetic models

artículo científico publicado en 2012

Area/moment and compartmental modeling of pharmacokinetics during pregnancy: applications to maternal/fetal exposures to corticosteroids in sheep and rats

artículo científico publicado en 2004

Assessing the dynamics of nuclear glucocorticoid-receptor complex: adding flexibility to gene expression modeling

artículo científico publicado en 2007

Assessment of Pharmacologic Area Under the Curve When Baselines are Variable ⬇️

artículo científico publicado el 14 de enero de 2011

Assessment of Three-Drug Combination Pharmacodynamic Interactions in Pancreatic Cancer Cells

artículo científico publicado en 2018

Assessment of basic indirect pharmacodynamic response models with physiological limits

artículo científico publicado en 2006

Assessment of dosing impact on intra-individual variability in estimation of parameters for basic indirect response models.

artículo científico publicado en 2006

Assessment of drug interactions relevant to pharmacodynamic indirect response models

artículo científico publicado en 2004

Assessment of non-linear combination effect terms for drug-drug interactions

artículo científico publicado en 2016

Attenuation of colistin bactericidal activity by high inoculum of Pseudomonas aeruginosa characterized by a new mechanism-based population pharmacodynamic model

artículo científico publicado en 2010

Betamethasone pharmacokinetics after two prodrug formulations in sheep: implications for antenatal corticosteroid use

artículo científico publicado en 2005

Biodistribution of etanercept to tissues and sites of inflammation in arthritic rats

artículo científico publicado en 2015

Ceftriaxone disposition in open-heart surgery patients

artículo científico publicado en 1989

Characterization and Interspecies Scaling of rhTNF-α Pharmacokinetics with Minimal Physiologically Based Pharmacokinetic Models

artículo científico publicado en 2017

Circadian rhythms in gene expression: Relationship to physiology, disease, drug disposition and drug action

artículo científico publicado en 2010

Circadian signatures in rat liver: from gene expression to pathways ⬇️

artículo científico publicado el 1 de noviembre de 2010

Circadian variations in gene expression in rat abdominal adipose tissue and relationship to physiology ⬇️

artículo científico publicado el 3 de agosto de 2010

Circadian variations in rat liver gene expression: relationships to drug actions

artículo científico publicado en 2008

Clarification of contraceptive drug pharmacokinetics in obesity

artículo científico publicado en 2016

Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regulatory structures ⬇️

artículo científico publicado el 14 de octubre de 2010

Comparative pharmacokinetics of coumarin anticoagulants L: Physiologic modeling of S-warfarin in rats and pharmacologic target-mediated warfarin disposition in man.

artículo científico publicado en 2003

Comparison of dexamethasone pharmacokinetics in female rats after intravenous and intramuscular administration

artículo científico publicado en 2005

Context specific transcription factor prediction

artículo científico publicado en 2007

Corticosteroid-regulated genes in rat kidney: mining time series array data

artículo científico publicado en 2005

D-optimal designs for parameter estimation for indirect pharmacodynamic response models

artículo científico publicado en 2009

Daily variation of gene expression in diverse rat tissues.

artículo científico publicado en 2018

Development and qualification of a pharmacodynamic model for the pronounced inoculum effect of ceftazidime against Pseudomonas aeruginosa

artículo científico publicado en 2008

Development and translational application of a minimal physiologically-based pharmacokinetic (mPBPK) model for a monoclonal antibody (mAb) against interleukin 23 (IL-23) in IL-23-induced psoriasis-like (PsL) mice

artículo científico publicado en 2018

Diabetes disease progression in Goto-Kakizaki rats: effects of salsalate treatment

artículo científico publicado en 2014

Differential muscle gene expression as a function of disease progression in Goto-Kakizaki diabetic rats ⬇️

artículo científico publicado el 26 de febrero de 2011

Disposition of methylprednisolone and its sodium succinate prodrug in vivo and in perfused liver of rats: nonlinear and sequential first-pass elimination

artículo científico publicado en 1991

Diversity of mechanism-based pharmacodynamic models

artículo científico publicado en 2003

Dose Equivalency Evaluation of Major Corticosteroids: Pharmacokinetics and Cell Trafficking and Cortisol Dynamics ⬇️

artículo científico publicado el 1 de noviembre de 2003

Dose- and time-related effect of troleandomycin on methylprednisolone elimination

artículo científico publicado en 1982

Dose-dependent pharmacokinetics of mezlocillin in rats

artículo científico publicado en 1989

Down-regulation of heat shock protein 70 improves arsenic trioxide and 17-DMAG effects on constitutive signal transducer and activator of transcription 3 activity

artículo científico publicado en 2009

Dynamic modeling of methylprednisolone effects on body weight and glucose regulation in rats ⬇️

artículo científico publicado el 11 de marzo de 2011

Effect of Disease-Related Changes in Plasma Albumin on the Pharmacokinetics of Naproxen in Male and Female Arthritic Rats

artículo científico publicado en 2017

Effect of chronic oral contraceptive steroids on theophylline disposition

artículo científico publicado en 1982

Effects of High Fat Feeding on Adipose Tissue Gene Expression in Diabetic Goto-Kakizaki Rats

artículo científico publicado en 2015

Effects of High-Fat Feeding on Skeletal Muscle Gene Expression in Diabetic Goto-Kakizaki Rats

artículo científico publicado en 2017

Effects of high fat feeding on liver gene expression in diabetic goto-kakizaki rats

artículo científico publicado en 2012

Effects of ketoconazole on methylprednisolone pharmacokinetics and cortisol secretion

scientific article published on 01 June 1986

Effects of ritonavir-boosted protease inhibitors on combined oral contraceptive pharmacokinetics and pharmacodynamics in HIV-positive women

artículo científico publicado en 2019

Endogenous histamine and cortisol levels in subjects with different histamine N-methyltransferase C314T genotypes : a pilot study

artículo científico publicado en 2006

Erratum to: Translational Biomarkers: from Preclinical to Clinical a Report of 2009 AAPS/ACCP Biomarker Workshop

scholarly article published in The AAPS Journal

Evaluation of Timing and Route of Epinephrine in a Neonatal Model of Asphyxial Arrest.

artículo científico publicado en 2017

Evidence for a glucocorticoid receptor beta splice variant in the rat and its physiological regulation in liver

artículo científico publicado en 2012

Exposure-Response Analysis of Vamorolone (VBP15) in Boys With Duchenne Muscular Dystrophy

artículo científico publicado en 2020

Fifth-generation model for corticosteroid pharmacodynamics: application to steady-state receptor down-regulation and enzyme induction patterns during seven-day continuous infusion of methylprednisolone in rats

artículo científico publicado en 2002

First-dose pharmacokinetics of lithium carbonate in children and adolescents

artículo científico publicado en 2010

Functional proteomic analysis of corticosteroid pharmacodynamics in rat liver: Relationship to hepatic stress, signaling, energy regulation, and drug metabolism

artículo científico publicado en 2017

Gender-based effects on methylprednisolone pharmacokinetics and pharmacodynamics

artículo científico publicado en 1993

Gene arrays and temporal patterns of drug response: corticosteroid effects on rat liver

artículo científico publicado en 2003

Gene expression analysis of hepatic roles in cause and development of diabetes in Goto-Kakizaki rats

artículo científico publicado en 2008

Glucocorticoid effects on adiponectin expression

artículo científico publicado en 2012

Glucocorticoid efficacy in asthma: is improved tissue remodeling upstream of anti-inflammation

artículo científico publicado en 2010

Highly multiplexed and reproducible ion-current-based strategy for large-scale quantitative proteomics and the application to protein expression dynamics induced by methylprednisolone in 60 rats

artículo científico publicado en 2014

Immunosuppressive interactions among calcium channel antagonists and selected corticosteroids and macrolides using human whole blood lymphocytes

artículo científico publicado en 2004

Importance of replication in analyzing time-series gene expression data: corticosteroid dynamics and circadian patterns in rat liver

artículo científico publicado en 2010

In vivo multi-tissue corticosteroid microarray time series available online at Public Expression Profile Resource (PEPR).

artículo científico publicado en 2003

Incorporating target-mediated drug disposition in a minimal physiologically-based pharmacokinetic model for monoclonal antibodies

artículo científico publicado en 2014

Indirect pharmacodynamic models for responses with circadian removal

scientific article published on 29 January 2019

Induction of imatinib metabolism by hypericum perforatum

artículo científico publicado en 2004

Integrated QSPR--pharmacodynamic model of genomic effects of several corticosteroids

artículo científico publicado en 2003

Interactions of Tofacitinib and Dexamethasone on Lymphocyte Proliferation

scientific article published on 26 May 2020

Interactions of everolimus and sorafenib in pancreatic cancer cells

artículo científico publicado en 2012

Interactions of everolimus and sorafenib in whole blood lymphocyte proliferation

artículo científico publicado en 2012

Interactions of prednisolone and other immunosuppressants used in dual treatment of systemic lupus erythematosus in lymphocyte proliferation assays

artículo científico publicado en 2004

Interrelationships between Infliximab and Recombinant Tumor Necrosis Factor-α in Plasma Using Minimal Physiologically Based Pharmacokinetic Models

artículo científico publicado en 2017

Interspecies comparisons of pharmacokinetics and pharmacodynamics of recombinant human erythropoietin

artículo científico publicado en 2007

Journal editor's final report

scientific article published on 01 December 2019

Ketoconazole effects on methylprednisolone disposition and their joint suppression of endogenous cortisol

scientific article published on 01 October 1987

Kinetics of betamethasone and fetal cardiovascular adverse effects in pregnant sheep after different doses

artículo científico publicado en 2006

Light-dark oscillations in the lung transcriptome: implications for lung homeostasis, repair, metabolism, disease, and drug action ⬇️

artículo científico publicado el 24 de marzo de 2011

Mathematical assessment of properties of precursor-dependent indirect pharmacodynamic response models

artículo científico publicado en 2006

Mathematical modeling of corticosteroid pharmacogenomics in rat muscle following acute and chronic methylprednisolone dosing

artículo científico publicado en 2008

Mechanism-based disease progression modeling of type 2 diabetes in Goto-Kakizaki rats ⬇️

artículo científico publicado el 3 de diciembre de 2010

Mechanism-based mathematical modeling of combined gemcitabine and birinapant in pancreatic cancer cells

artículo científico publicado en 2015

Mechanism-based modeling of nutritional and leptin influences on growth in normal and type 2 diabetic rats

artículo científico publicado en 2008

Mechanism-based population modelling for assessment of L-cell function based on total GLP-1 response following an oral glucose tolerance test

artículo científico publicado en 2011

Mechanism-based population pharmacokinetic and pharmacodynamic modeling of intravenous and intranasal dexmedetomidine in healthy subjects.

artículo científico publicado en 2015

Mechanism‐based population modelling of the effects of vildagliptin on GLP‐1, glucose and insulin in patients with type 2 diabetes ⬇️

artículo científico publicado el 1 de marzo de 2012

Mechanism‐based population pharmacokinetic modelling in diabetes: vildagliptin as a tight binding inhibitor and substrate of dipeptidyl peptidase IV ⬇️

artículo científico publicado el 1 de marzo de 2012

Mechanistic Modeling of the Effects of Glucocorticoids and Circadian Rhythms on Adipokine Expression ⬇️

artículo científico publicado el 11 de marzo de 2011

Mechanistic Multi-Tissue Modeling of Glucocorticoid-Induced Leucine Zipper Regulation: Integrating Circadian Gene Expression with Receptor-Mediated Corticosteroid Pharmacodynamics

artículo científico publicado en 2017

Mechanistic population modeling of diabetes disease progression in Goto‐Kakizaki rat muscle ⬇️

artículo científico publicado el 5 de diciembre de 2010

Mechanistic population pharmacokinetics of total and unbound paclitaxel for a new nanodroplet formulation versus Taxol in cancer patients

artículo científico publicado en 2008

Meta-modeling of methylprednisolone effects on glucose regulation in rats

artículo científico publicado en 2013

Methods of utilizing baseline values for indirect response models

artículo científico publicado en 2009

Microarray analysis of the temporal response of skeletal muscle to methylprednisolone: comparative analysis of two dosing regimens

artículo científico publicado en 2007

Minimal physiologically-based pharmacokinetic (mPBPK) model for a monoclonal antibody against interleukin-6 in mice with collagen-induced arthritis.

artículo científico publicado en 2016

Model-based development of a PPARgamma agonist, rivoglitazone, to aid dose selection and optimize clinical trial designs

artículo científico publicado en 2008

Modeling Combined Anti-Inflammatory Effects of Dexamethasone and Tofacitinib in Arthritic Rats

scientific article published on 24 July 2019

Modeling Combined Immunosuppressive and Anti-inflammatory Effects of Dexamethasone and Naproxen in Rats Predicts the Steroid-Sparing Potential of Naproxen

artículo científico publicado en 2017

Modeling Corticosteroid Pharmacogenomics and Proteomics in Rat Liver

scientific article published on 07 August 2018

Modeling Corticosteroid Pharmacokinetics and Pharmacodynamics, Part I: Determination and Prediction of Dexamethasone and Methylprednisolone Tissue Binding in the Rat

scientific article published on 13 June 2019

Modeling Corticosteroid Pharmacokinetics and Pharmacodynamics, Part II: Sex Differences in Methylprednisolone Pharmacokinetics and Corticosterone Suppression

scientific article published on 13 June 2019

Modeling Corticosteroid Pharmacokinetics and Pharmacodynamics, Part III: Estrous Cycle and Estrogen Receptor-Dependent Antagonism of Glucocorticoid-Induced Leucine Zipper (GILZ) Enhancement by Corticosteroids ⬇️

artículo científico publicado en 2019

Modeling Diabetes Disease Progression and Salsalate Intervention in Goto-Kakizaki Rats ⬇️

artículo científico publicado el 8 de septiembre de 2011

Modeling Disease Progression and Rosiglitazone Intervention in Type 2 Diabetic Goto-Kakizaki Rats ⬇️

artículo científico publicado el 29 de febrero de 2012

Modeling Pathway Dynamics of the Skeletal Muscle Response to Intravenous Methylprednisolone (MPL) Administration in Rats: Dosing and Tissue Effects

artículo científico publicado en 2020

Modeling Sex Differences in Anti-inflammatory Effects of Dexamethasone in Arthritic Rats

scientific article published on 06 September 2018

Modeling Sex Differences in Pharmacokinetics, Pharmacodynamics, and Disease Progression Effects of Naproxen in Rats with Collagen-Induced Arthritis

artículo científico publicado en 2017

Modeling circadian rhythms of glucocorticoid receptor and glutamine synthetase expression in rat skeletal muscle

scientific journal article

Modeling circadian variability of core-clock and clock-controlled genes in four tissues of the rat.

artículo científico publicado en 2018

Modeling corticosteroid effects in a rat model of rheumatoid arthritis I: mechanistic disease progression model for the time course of collagen-induced arthritis in Lewis rats

artículo científico publicado en 2008

Modeling corticosteroid effects in a rat model of rheumatoid arthritis II: mechanistic pharmacodynamic model for dexamethasone effects in Lewis rats with collagen-induced arthritis

artículo científico publicado en 2008

Modeling effects of dexamethasone on disease progression of bone mineral density in collagen-induced arthritic rats

artículo científico publicado en 2015

Modeling glucocorticoid-mediated fetal lung maturation: I. Temporal patterns of corticosteroids in rat pregnancy

artículo científico publicado en 2005

Modeling glucocorticoid-mediated fetal lung maturation: II. Temporal patterns of gene expression in fetal rat lung

scientific journal article

Modeling of corticosteroid effects on hepatic low-density lipoprotein receptors and plasma lipid dynamics in rats

artículo científico publicado en 2007

Modeling of corticosteroid pharmacogenomics in rat liver using gene microarrays

artículo científico publicado en 2003

Modeling pharmacokinetics/pharmacodynamics of abatacept and disease progression in collagen-induced arthritic rats: a population approach

artículo científico publicado en 2013

Modeling receptor/gene-mediated effects of corticosteroids on hepatic tyrosine aminotransferase dynamics in rats: dual regulation by endogenous and exogenous corticosteroids

artículo científico publicado en 2007

Modeling the metabolic effects of terbutaline in beta2-adrenergic receptor diplotypes.

artículo científico publicado en 2004

Moving from basic toward systems pharmacodynamic models

scientific article published on 16 May 2013

Multi-Scale Network Model Supported by Proteomics for Analysis of Combined Gemcitabine and Birinapant Effects in Pancreatic Cancer Cells

article

Multiple-dose pharmacokinetics of imipramine and its major active and conjugated metabolites in depressed patients

artículo científico publicado el 1 de febrero de 1988

Multiple-pool cell lifespan model of hematologic effects of anticancer agents

artículo científico publicado en 2002

Multiple-pool cell lifespan models for neutropenia to assess the population pharmacodynamics of unbound paclitaxel from two formulations in cancer patients

artículo científico publicado en 2008

Oral contraceptive effects on methylprednisolone pharmacokinetics and pharmacodynamics

scientific article published on 01 March 1996

Pathway-Based Analysis of the Liver Response to Intravenous Methylprednisolone Administration in Rats: Acute Versus Chronic Dosing

Perspectives on the history and scientific contributions of Gerhard Levy

artículo científico publicado en 2015

Perspectives on variability in pharmacokinetics of an oral contraceptive product

artículo científico publicado en 2016

Pharmacodynamic Modeling of Cell Cycle Effects for Gemcitabine and Trabectedin Combinations in Pancreatic Cancer Cells

artículo científico publicado en 2016

Pharmacodynamic interaction of recombinant human interleukin-10 and prednisolone using in vitro whole blood lymphocyte proliferation

artículo científico publicado en 2002

Pharmacodynamic interactions between recombinant mouse interleukin-10 and prednisolone using a mouse endotoxemia model

artículo científico publicado en 2005

Pharmacodynamic model for chemotherapy-induced anemia in rats

artículo científico publicado en 2007

Pharmacodynamic model for joint exogenous and endogenous corticosteroid suppression of lymphocyte trafficking

scientific article published on 01 December 1994

Pharmacodynamic modeling of acute and chronic effects of methylprednisolone on hepatic urea cycle genes in rats.

artículo científico publicado en 2008

Pharmacodynamic modeling of cell cycle and apoptotic effects of gemcitabine on pancreatic adenocarcinoma cells

artículo científico publicado en 2013

Pharmacodynamic modeling of combined chemotherapeutic effects predicts synergistic activity of gemcitabine and trabectedin in pancreatic cancer cells

artículo científico publicado en 2015

Pharmacodynamic modeling of cortisol suppression from fluocortolone

artículo científico publicado en 1993

Pharmacodynamic modeling of thrombopoietin, platelet, and megakaryocyte dynamics in patients with acute myeloid leukemia undergoing dose intensive chemotherapy

artículo científico publicado en 2002

Pharmacodynamic models for agents that alter production of natural cells with various distributions of lifespans

artículo científico publicado en 2006

Pharmacodynamic/pharmacogenomic modeling of insulin resistance genes in rat muscle after methylprednisolone treatment: exploring regulatory signaling cascades

artículo científico publicado en 2008

Pharmacodynamics and pharmacogenomics of diverse receptor-mediated effects of methylprednisolone in rats using microarray analysis

artículo científico publicado en 2002

Pharmacodynamics and pharmacogenomics of methylprednisolone during 7-day infusions in rats

artículo científico publicado en 2002

Pharmacodynamics of glucose regulation by methylprednisolone. I. Adrenalectomized rats

artículo científico publicado en 2009

Pharmacodynamics of glucose regulation by methylprednisolone. II. normal rats

artículo científico publicado en 2009

Pharmacogenomic Variability of Oral Baclofen Clearance and Clinical Response in Children With Cerebral Palsy.

artículo científico publicado en 2017

Pharmacogenomic responses of rat liver to methylprednisolone: an approach to mining a rich microarray time series

artículo científico publicado en 2005

Pharmacokinetic Interactions between Sirolimus and Microemulsion Cyclosporine When Orally Administered Jointly and 4 Hours Apart in Healthy Volunteers ⬇️

artículo científico publicado el 1 de octubre de 2003

Pharmacokinetic and Pharmacodynamic Modeling of Exendin-4 in Type 2 Diabetic Goto-Kakizaki Rats ⬇️

artículo científico publicado el 14 de diciembre de 2010

Pharmacokinetic and pharmacodynamic interactions between diltiazem and methylprednisolone in healthy volunteers

artículo científico publicado en 2002

Pharmacokinetic and pharmacodynamic modeling of a copper-selective chelator (TETA) in healthy adults

artículo científico publicado en 2009

Pharmacokinetic and pharmacodynamic modeling of humanized anti-factor IX antibody (SB 249417) in humans

artículo científico publicado en 2002

Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after intravenous and subcutaneous administration in rats

artículo científico publicado en 2006

Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after intravenous and subcutaneous dose administration in cynomolgus monkeys

artículo científico publicado en 2003

Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after multiple subcutaneous doses in healthy subjects

artículo científico publicado en 2005

Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after single and multiple doses in healthy volunteers

artículo científico publicado en 2004

Pharmacokinetic-pharmacodynamic disease progression model for effect of etanercept in Lewis rats with collagen-induced arthritis

artículo científico publicado en 2011

Pharmacokinetic/Pharmacodynamic Modeling of GLP-1 in Healthy Rats ⬇️

artículo científico publicado el 17 de diciembre de 2011

Pharmacokinetic/Pharmacodynamic Modeling of Methylprednisolone Effects on iNOS mRNA Expression and Nitric Oxide During LPS-Induced Inflammation in Rats ⬇️

artículo científico publicado el 16 de marzo de 2012

Pharmacokinetic/pharmacodynamic model for prednisolone inhibition of whole blood lymphocyte proliferation

artículo científico publicado en 2002

Pharmacokinetic/pharmacodynamic modeling of corticosterone suppression and lymphocytopenia by methylprednisolone in rats

scientific article published on July 2008

Pharmacokinetic/pharmacodynamic modeling of glucose clamp effects of inhaled and subcutaneous insulin in healthy volunteers and diabetic patients.

artículo científico publicado en 2010

Pharmacokinetic/pharmacodynamic modelling in diabetes mellitus.

artículo científico publicado en 2008

Pharmacokinetics and Pharmacodynamics of Intramuscular and Oral Betamethasone and Dexamethasone in Reproductive Age Women in India

scientific article published on 13 December 2019

Pharmacokinetics and antibody responses to the CD3 antibody otelixizumab used in the treatment of type 1 diabetes.

artículo científico publicado en 2010

Pharmacokinetics and bioequivalence of a liquid formulation of hydroxyurea in children with sickle cell anemia

artículo científico publicado en 2015

Pharmacokinetics and cell trafficking dynamics of 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride (FTY720) in cynomolgus monkeys after single oral and intravenous doses

artículo científico publicado en 2002

Pharmacokinetics and pharmacodynamic modeling of direct suppression effects of methylprednisolone on serum cortisol and blood histamine in human subjects

artículo científico publicado en 1989

Pharmacokinetics and pharmacodynamics of PEGylated IFN-beta 1a following subcutaneous administration in monkeys

artículo científico publicado en 2005

Pharmacokinetics and pharmacodynamics of a chimeric/humanized anti-CD3 monoclonal antibody, otelixizumab (TRX4), in subjects with psoriasis and with type 1 diabetes mellitus

artículo científico publicado en 2009

Pharmacokinetics and pharmacodynamics of liposomal chemophototherapy with short drug-light intervals

scientific article published on 23 January 2019

Pharmacokinetics and pharmacodynamics of methylprednisolone when administered at 8 am versus 4 pm.

artículo científico publicado en 1992

Pharmacokinetics of Hormonal Contraception in Individuals with Obesity: a Review

scientific article published on 04 May 2020

Pharmacokinetics of Inter-Alpha Inhibitor Proteins and Effects on Hemostasis after Hypoxic-Ischemic Brain Injury in Neonatal Rats

artículo científico publicado en 2020

Pharmacokinetics of dexamethasone in a rat model of rheumatoid arthritis

artículo científico publicado en 2008

Pharmacokinetics of methylprednisolone after intravenous and intramuscular administration in rats.

artículo científico publicado en 2007

Pharmacokinetics of methylprednisolone hemisuccinate and methylprednisolone in chronic liver disease

scientific article published on 01 September 1993

Pharmacokinetics of salsalate and salicylic acid in normal and diabetic rats

artículo científico publicado en 2012

Pharmacokinetics of single and multiple doses of ethinyl estradiol and levonorgestrel in relation to smoking

scientific article published on 01 January 1988

Pharmacokinetics of the 1.5 mg levonorgestrel emergency contraceptive in women with normal, obese and extremely obese body mass index

scientific article published on 28 January 2019

Pharmacokinetics, pharmacodynamics and toxicities of methotrexate in healthy and collagen-induced arthritic rats

artículo científico publicado en 2013

Phase IIa trial in Duchenne muscular dystrophy shows vamorolone is a first-in-class dissociative steroidal anti-inflammatory drug

scientific article published on 13 September 2018

Physiologically based pharmacokinetic modeling of FTY720 (2-amino-2[2-(-4-octylphenyl)ethyl]propane-1,3-diol hydrochloride) in rats after oral and intravenous doses.

artículo científico publicado en 2006

Physiologically based pharmacokinetic models for everolimus and sorafenib in mice

artículo científico publicado en 2013

Physiologically-Based Pharmacokinetic Modeling Involving Nonlinear Plasma and Tissue Binding: Application to Prednisolone and Prednisone in Rats

scientific article published on 03 September 2020

Physiologically-Based Pharmacokinetics of Dexamethasone in Rats

artículo científico publicado en 2020

Physiologically-based pharmacokinetic and pharmacodynamic models for gemcitabine and birinapant in pancreatic cancer xenografts

artículo científico publicado en 2018

Population Pharmacokinetics of Vamorolone (VBP15) in Healthy Men and Boys With Duchenne Muscular Dystrophy

scientific article published on 11 February 2019

Population cell life span models for effects of drugs following indirect mechanisms of action

artículo científico publicado en 2005

Population pharmacodynamic modeling of intramuscular and oral dexamethasone and betamethasone effects on six biomarkers with circadian complexities in Indian women

artículo científico publicado en 2021

Population pharmacokinetic modeling of intramuscular and oral dexamethasone and betamethasone in Indian women

artículo científico publicado en 2021

Population pharmacokinetic/pharmacodynamic modeling of systemic corticosteroid inhibition of whole blood lymphocytes: modeling interoccasion pharmacodynamic variability

artículo científico publicado en 2007

Population pharmacokinetics and pharmacodynamics of peptidic erythropoiesis receptor agonist (ERA) in healthy volunteers

artículo científico publicado en 2007

Population pharmacokinetics of oral baclofen in pediatric patients with cerebral palsy

artículo científico publicado en 2014

Population pharmacokinetics of prednisolone in children with acute lymphoblastic leukemia

artículo científico publicado en 2003

Population pharmacokinetic–pharmacodynamic–disease progression model for effects of anakinra in Lewis rats with collagen-induced arthritis ⬇️

artículo científico publicado el 16 de octubre de 2011

Prednisolone disposition in steroid-dependent asthmatics

artículo científico publicado en 1980

Prednisone metabolism in recipients of kidney or liver transplants and in lung recipients receiving ketoconazole

artículo científico publicado en 2003

Preface to the special issue to honor Gerhard Levy and 50 years of PK/PD

scientific article published on 01 October 2015

Proteomic Analysis of Combined Gemcitabine and Birinapant in Pancreatic Cancer Cells.

artículo científico publicado en 2018

Quantification of dexamethasone and corticosterone in rat biofluids and fetal tissue using highly sensitive analytical methods: assay validation and application to a pharmacokinetic study

artículo científico publicado en 2007

Quantitative dynamic models of arthritis progression in the rat

artículo científico publicado en 2008

Quantitative structure-pharmacokinetic/pharmacodynamic relationships of corticosteroids in man.

artículo científico publicado en 2002

Quantitative tissue-specific dynamics of in vivo GILZ mRNA expression and regulation by endogenous and exogenous glucocorticoids

artículo científico publicado en 2015

Receptor-mediated pharmacodynamics of prednisolone in the rat

scientific article published on 01 October 1986

Receptor-mediated pharmacokinetic/pharmacodynamic model of interferon-beta 1a in humans

artículo científico publicado en 2002

Receptor-mediated pharmacokinetics and pharmacodynamics of interferon-beta1a in monkeys

artículo científico publicado en 2003

Receptor/gene-mediated pharmacodynamic effects of methylprednisolone on phosphoenolpyruvate carboxykinase regulation in rat liver

artículo científico publicado en 2004

Receptor/gene/protein-mediated signaling connects methylprednisolone exposure to metabolic and immune-related pharmacodynamic actions in liver

artículo científico publicado en 2018

Reduced methylprednisolone clearance causing prolonged pharmacodynamics in a healthy subject was not associated with CYP3A5*3 allele or a change in diet composition

artículo científico publicado en 2006

Relationship of serum thiocyanate concentrations to smoking characteristics

artículo científico publicado en 1984

Relationships between circadian rhythms and modulation of gene expression by glucocorticoids in skeletal muscle

artículo científico publicado en 2008

Relative immunosuppressive potency of therapeutic corticosteroids measured by whole blood lymphocyte proliferation

artículo científico publicado en 2003

Report of the 2011-2012 AACP Special Advisory Committee on Research and Graduate Education

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