Lista de obras -

A two-state model for the diffusion of the A2A adenosine receptor in hippocampal neurons: agonist-induced switch to slow mobility is modified by synapse-associated protein 102 (SAP102)

artículo científico publicado en 2014

ABC transporters of Fasciola hepatica as putative drug targets

artículo científico publicado en 2011

ABC transporters of the liver fluke

ARNO/cytohesin-2 regulates desensitization of the Aadenosine receptor in rat pheochromocytoma cells

Aadenosine receptor interacting partners (interactome)

artículo científico publicado en 2009

Activation and inhibition of G proteins by lipoamines

artículo científico publicado en 2002

Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters

artículo científico publicado en 2013

Amphetamine action at the cocaine- and antidepressant-sensitive serotonin transporter is modulated by αCaMKII.

artículo científico publicado en 2015

Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate

artículo científico publicado en 2013

Amphetamines take two to tango: an oligomer-based counter-transport model of neurotransmitter transport explores the amphetamine action

An unsuspected role for organic cation transporter 3 in the actions of amphetamine

artículo científico publicado en 2018

Biased inhibition by a suramin analogue of A1-adenosine receptor/G protein coupling in fused receptor/G protein tandems: the A1-adenosine receptor is predominantly coupled to Goalpha in human brain.

artículo científico publicado en 2001

Ca(2+)/calmodulin-dependent protein kinase IIα (αCaMKII) controls the activity of the dopamine transporter: implications for Angelman syndrome.

artículo científico publicado en 2012

Calmodulin kinase II regulates amphetamine-induced reverse transport in dopamine and serotonin transporters

artículo científico publicado en 2012

Calmodulin kinase II regulates amphetamine-induced reverse transport in the dopamine transporter: implications for the importance of the dopamine transporter in Angelman syndrome.

artículo científico publicado en 2010

Cocaine adulteration

artículo científico publicado en 2017

Combined Simulation and Mutation Studies to Elucidate Selectivity of Unsubstituted Amphetamine-like Cathinones at the Dopamine Transporter

artículo científico publicado en 2016

Consequences of loss of PINCH2 expression in mice

artículo científico publicado en 2005

Decrypting structural and functional changes in LeuTAa at atomic level employing LRET

Development of Gs-Selective Inhibitory Compounds ⬇️

artículo científico publicado el 1 de enero de 2002

Direct PIP2 binding mediates stable oligomer formation of the serotonin transporter

artículo científico publicado en 2017

Dopamine transporter forms stable dimers in the live cell plasma membrane in a phosphatidylinositol 4,5-bisphosphate-independent manner

artículo científico publicado en 2019

Fluorescence resonance energy transfer (FRET) sensors

ILK, PINCH and parvin: the tIPP of integrin signalling

artículo científico publicado en 2006

Identification and characterization of the Fasciola hepatica sodium- and chloride-dependent taurine transporter.

artículo científico publicado en 2018

Identification of an additional interaction domain in transmembrane domains 11 and 12 that supports oligomer formation in the human serotonin transporter.

artículo científico publicado en 2003

Importance of the carboxyl terminus for folding and trafficking of the serotonin transporter

artículo científico publicado en 2009

In vivo amphetamine action is contingent on αCaMKII

artículo científico publicado en 2014

Interaction between fast and ultra-slow inactivation in the voltage-gated sodium channel. Does the inactivation gate stabilize the channel structure?

artículo científico publicado en 2002

Jak1 deficiency leads to enhanced Abelson-induced B-cell tumor formation

artículo científico publicado en 2003

MAP kinase stimulation by cAMP does not require RAP1 but SRC family kinases

artículo científico publicado en 2002

Mechanism of hERG channel block by the psychoactive indole alkaloid ibogaine.

artículo científico publicado en 2013

Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation

scientific journal article

Mutational analysis of the high-affinity zinc binding site validates a refined human dopamine transporter homology model

artículo científico publicado en 2013

Mutations in the amino-terminus impair amphetamine-induced efflux by inducing inward-facing conformations of the serotonin transporter

scholarly article by Sonja Sucic et al published 2009 in BMC Pharmacology

Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter.

artículo científico publicado en 2010

Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites

artículo científico publicado en 2015

PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage

scientific journal article

Recruitment of a cytoplasmic chaperone relay by the A2A adenosine receptor.

artículo científico publicado en 2013

Restricted collision coupling of the A2A receptor revisited: evidence for physical separation of two signaling cascades

artículo científico publicado en 2008

Selectivity filter residues contribute unequally to pore stabilization in voltage-gated sodium channels

scientific article published on 01 October 2005

Single molecule analysis reveals coexistence of stable serotonin transporter monomers and oligomers in the live cell plasma membrane.

scientific article published on 06 January 2014

Structure and regulatory interactions of the cytoplasmic terminal domains of serotonin transporter.

artículo científico publicado en 2014

Switching the clientele: a lysine residing in the C terminus of the serotonin transporter specifies its preference for the coat protein complex II component SEC24C

artículo científico publicado en 2013

The N terminus of monoamine transporters is a lever required for the action of amphetamines

artículo científico publicado en 2010

The folding interactome of GPCRs

The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells.

artículo científico publicado en 2003

The interactome of the A2A adenosine receptor in vitro and in vivo.

artículo científico publicado en 2010

The presence of phosphatidylinositol-4,5-bisphosphate directly impacts on amphetamine-induced serotonin transporter-mediated efflux

The role of the carboxyl terminus in folding of the serotonin transporter.

artículo científico publicado en 2010

The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C.

artículo científico publicado en 2011

Truncations in the amino terminus reveal a region key to supporting amphetamine-induced efflux by the human serotonin transporter

scholarly article by Sonja Sucic et al published 2011 in BMC Pharmacology

Two discontinuous segments in the carboxyl terminus are required for membrane targeting of the rat gamma-aminobutyric acid transporter-1 (GAT1)

scientific journal article

Lista de obras de

A two-state model for the diffusion of the A2A adenosine receptor in hippocampal neurons: agonist-induced switch to slow mobility is modified by synapse-associated protein 102 (SAP102)

ABC transporters of Fasciola hepatica as putative drug targets

ABC transporters of the liver fluke

ARNO/cytohesin-2 regulates desensitization of the Aadenosine receptor in rat pheochromocytoma cells

Aadenosine receptor interacting partners (interactome)

Activation and inhibition of G proteins by lipoamines

Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters

Amphetamine action at the cocaine- and antidepressant-sensitive serotonin transporter is modulated by αCaMKII.

Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate

Amphetamines take two to tango: an oligomer-based counter-transport model of neurotransmitter transport explores the amphetamine action

An unsuspected role for organic cation transporter 3 in the actions of amphetamine

Biased inhibition by a suramin analogue of A1-adenosine receptor/G protein coupling in fused receptor/G protein tandems: the A1-adenosine receptor is predominantly coupled to Goalpha in human brain.

Ca(2+)/calmodulin-dependent protein kinase IIα (αCaMKII) controls the activity of the dopamine transporter: implications for Angelman syndrome.

Calmodulin kinase II regulates amphetamine-induced reverse transport in dopamine and serotonin transporters

Calmodulin kinase II regulates amphetamine-induced reverse transport in the dopamine transporter: implications for the importance of the dopamine transporter in Angelman syndrome.

Cocaine adulteration

Combined Simulation and Mutation Studies to Elucidate Selectivity of Unsubstituted Amphetamine-like Cathinones at the Dopamine Transporter

Consequences of loss of PINCH2 expression in mice

Decrypting structural and functional changes in LeuTAa at atomic level employing LRET

Development of Gs-Selective Inhibitory Compounds ⬇️

Direct PIP2 binding mediates stable oligomer formation of the serotonin transporter

Dopamine transporter forms stable dimers in the live cell plasma membrane in a phosphatidylinositol 4,5-bisphosphate-independent manner

Fluorescence resonance energy transfer (FRET) sensors

ILK, PINCH and parvin: the tIPP of integrin signalling

Identification and characterization of the Fasciola hepatica sodium- and chloride-dependent taurine transporter.

Identification of an additional interaction domain in transmembrane domains 11 and 12 that supports oligomer formation in the human serotonin transporter.

Importance of the carboxyl terminus for folding and trafficking of the serotonin transporter

In vivo amphetamine action is contingent on αCaMKII

Interaction between fast and ultra-slow inactivation in the voltage-gated sodium channel. Does the inactivation gate stabilize the channel structure?

Jak1 deficiency leads to enhanced Abelson-induced B-cell tumor formation

MAP kinase stimulation by cAMP does not require RAP1 but SRC family kinases

Mechanism of hERG channel block by the psychoactive indole alkaloid ibogaine.

Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation

Mutational analysis of the high-affinity zinc binding site validates a refined human dopamine transporter homology model

Mutations in the amino-terminus impair amphetamine-induced efflux by inducing inward-facing conformations of the serotonin transporter

Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter.

Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites

PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage

Recruitment of a cytoplasmic chaperone relay by the A2A adenosine receptor.

Restricted collision coupling of the A2A receptor revisited: evidence for physical separation of two signaling cascades

Selectivity filter residues contribute unequally to pore stabilization in voltage-gated sodium channels

Single molecule analysis reveals coexistence of stable serotonin transporter monomers and oligomers in the live cell plasma membrane.

Structure and regulatory interactions of the cytoplasmic terminal domains of serotonin transporter.

Switching the clientele: a lysine residing in the C terminus of the serotonin transporter specifies its preference for the coat protein complex II component SEC24C

The N terminus of monoamine transporters is a lever required for the action of amphetamines

The folding interactome of GPCRs

The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells.

The interactome of the A2A adenosine receptor in vitro and in vivo.

The presence of phosphatidylinositol-4,5-bisphosphate directly impacts on amphetamine-induced serotonin transporter-mediated efflux

The role of the carboxyl terminus in folding of the serotonin transporter.

The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C.

Truncations in the amino terminus reveal a region key to supporting amphetamine-induced efflux by the human serotonin transporter

Two discontinuous segments in the carboxyl terminus are required for membrane targeting of the rat gamma-aminobutyric acid transporter-1 (GAT1)