Lista de obras -

A cell-penetrating helical peptide as a potential HIV-1 inhibitor

artículo científico publicado en 2008

A predicted receptor-binding and critical neutralizing domain in S protein of the novel human coronavirus HCoV-EMC.

artículo científico publicado en 2012

ADS-J1 inhibits human immunodeficiency virus type 1 entry by interacting with the gp41 pocket region and blocking fusion-active gp41 core formation

artículo científico publicado en 2009

Active amino acids of the Kell blood group protein and model of the ectodomain based on the structure of neutral endopeptidase 24.11.

artículo científico publicado en 2003

Allosteric inhibition of the nonMyristoylated c-Abl tyrosine kinase by phosphopeptides derived from Abi1/Hssh3bp1

artículo científico publicado en 2008

Anti-HIV-1 activity of cellulose acetate phthalate: synergy with soluble CD4 and induction of "dead-end" gp41 six-helix bundles

artículo científico publicado en 2002

Antiviral Activity of Dual-acting Hydrocarbon-stapled Peptides against HIV-1 Predominantly Circulating in China

artículo científico publicado en 2017

Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain ⬇️

artículo científico publicado en 2011

Approaches for identification of HIV-1 entry inhibitors targeting gp41 pocket

artículo científico publicado en 2013

Binding mode characterization of NBD series CD4-mimetic HIV-1 entry inhibitors by X-ray structure and resistance study

artículo científico publicado en 2014

Comparative Pharmacokinetics of a Dual Inhibitor of HIV-1, NBD-14189, in Rats and Dogs with a Proof-of-Concept Evaluation of Antiviral Potency in SCID-hu Mouse Model

artículo científico publicado en 2022

Conserved salt bridge between the N- and C-terminal heptad repeat regions of the human immunodeficiency virus type 1 gp41 core structure is critical for virus entry and inhibition

artículo científico publicado en 2008

Correction to Synthesis, Antiviral Potency, in Vitro ADMET, and X-ray Structure of Potent CD4 Mimics as Entry Inhibitors That Target the Phe43 Cavity of HIV-1 gp120.

artículo científico publicado en 2017

Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site

artículo científico publicado en 2014

Design of antiviral stapled peptides containing a biphenyl cross-linker

scientific article published on 22 February 2014

Design, Synthesis, and Antiviral Activity of Entry Inhibitors That Target the CD4-Binding Site of HIV-1 ⬇️

artículo científico publicado el 10 de mayo de 2012

Design, Synthesis, and Biological Activity of Novel 5-((Arylfuran/1H-pyrrol-2-yl)methylene)-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-4-ones as HIV-1 Fusion Inhibitors Targeting gp41 ⬇️

artículo científico publicado el 29 de diciembre de 2010

Design, synthesis and evaluation of small molecule CD4-mimics as entry inhibitors possessing broad spectrum anti-HIV-1 activity.

artículo científico publicado en 2016

Design, synthesis, and structure-activity relationship of a novel series of 2-aryl 5-(4-oxo-3-phenethyl-2-thioxothiazolidinylidenemethyl)furans as HIV-1 entry inhibitors

artículo científico publicado en 2009

Development of Small-molecule HIV Entry Inhibitors Specifically Targeting gp120 or gp41

artículo científico publicado en 2015

Dual-acting stapled peptides target both HIV-1 entry and assembly

artículo científico publicado en 2013

Identification of Combinations of Protein Kinase C Activators and Histone Deacetylase Inhibitors That Potently Reactivate Latent HIV

artículo científico publicado en 2020

Identification of a receptor-binding domain in the S protein of the novel human coronavirus Middle East respiratory syndrome coronavirus as an essential target for vaccine development

artículo científico publicado en 2013

Molecular basis of two novel and related high‐prevalence antigens in the Kell blood group system, KUCI and KANT, and their serologic and spatial association with K11 and KETI ⬇️

artículo científico publicado el 8 de abril de 2013

N-substituted pyrrole derivatives as novel human immunodeficiency virus type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus fusion

artículo científico publicado en 2004

Novel anti-HIV peptides containing multiple copies of artificially designed heptad repeat motifs

artículo científico publicado en 2008

Novel structures of self-associating stapled peptides

artículo científico publicado en 2011

Peptide and non-peptide HIV fusion inhibitors

artículo científico publicado en 2002

Preclinical Optimization of gp120 Entry Antagonists as anti-HIV-1 Agents with Improved Cytotoxicity and ADME Properties through Rational Design, Synthesis, and Antiviral Evaluation

artículo científico publicado en 2020

Progress in identifying peptides and small-molecule inhibitors targeted to gp41 of HIV-1.

artículo científico publicado en 2006

Prospects and strategies for the discovery and development of small-molecule inhibitors of six-helix bundle formation in class 1 viral fusion proteins

artículo científico publicado en 2006

Punica granatum (Pomegranate) juice provides an HIV-1 entry inhibitor and candidate topical microbicide

artículo científico publicado en 2004

Punica granatum (pomegranate) juice provides an HIV-1 entry inhibitor and candidate topical microbicide.

artículo científico publicado en 2005

Putative conformations of the receptor-binding domain in S protein of hCoV-EMC in complex with its receptor dipeptidyl peptidase-4.

artículo científico publicado en 2013

Rational Design of HIV-1 Entry Inhibitors ⬇️

artículo científico publicado el 1 de enero de 2013

Solution Structure of a Hydrocarbon Stapled Peptide Inhibitor in Complex with Monomeric C-terminal Domain of HIV-1 Capsid

artículo científico publicado en 2008

Structure-Based Design of a Small Molecule CD4-Antagonist with Broad Spectrum Anti-HIV-1 Activity

artículo científico publicado en 2015

Structure-based identification and neutralization mechanism of tyrosine sulfate mimetics that inhibit HIV-1 entry

artículo científico publicado en 2011

Synthesis of 2-Oxo-1, 2-Dihydroquinoline Chemotype with Multiple Attachment Points as Novel Screening Compounds for Drug Discovery

artículo científico publicado en 2016

Synthesis, Antiviral Activity, and Structure-Activity Relationship of 1,3-Benzodioxolyl Pyrrole-Based Entry Inhibitors Targeting the Phe43 Cavity in HIV-1 gp120

article

Synthesis, Antiviral Potency, in Vitro ADMET, and X-ray Structure of Potent CD4 Mimics as Entry Inhibitors That Target the Phe43 Cavity of HIV-1 gp120.

artículo científico publicado en 2017

Synthesis, antiviral activity and resistance of a novel small molecule HIV-1 entry inhibitor

artículo científico publicado en 2015

The conserved residue Arg46 in the N-terminal heptad repeat domain of HIV-1 gp41 is critical for viral fusion and entry

artículo científico publicado en 2012

Theaflavin derivatives in black tea and catechin derivatives in green tea inhibit HIV-1 entry by targeting gp41

artículo científico publicado en 2005

Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops

artículo científico publicado en 2012

Viral inhibition studies on sulfated lignin, a chemically modified biopolymer and a potential mimic of heparan sulfate.

artículo científico publicado en 2007

Virtual screening based identification of novel small-molecule inhibitors targeted to the HIV-1 capsid

artículo científico publicado en 2010

XTT formazan widely used to detect cell viability inhibits HIV type 1 infection in vitro by targeting gp41.

artículo científico publicado en 2002

Lista de obras de

A cell-penetrating helical peptide as a potential HIV-1 inhibitor

A predicted receptor-binding and critical neutralizing domain in S protein of the novel human coronavirus HCoV-EMC.

ADS-J1 inhibits human immunodeficiency virus type 1 entry by interacting with the gp41 pocket region and blocking fusion-active gp41 core formation

Active amino acids of the Kell blood group protein and model of the ectodomain based on the structure of neutral endopeptidase 24.11.

Allosteric inhibition of the nonMyristoylated c-Abl tyrosine kinase by phosphopeptides derived from Abi1/Hssh3bp1

Anti-HIV-1 activity of cellulose acetate phthalate: synergy with soluble CD4 and induction of "dead-end" gp41 six-helix bundles

Antiviral Activity of Dual-acting Hydrocarbon-stapled Peptides against HIV-1 Predominantly Circulating in China

Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain ⬇️

Approaches for identification of HIV-1 entry inhibitors targeting gp41 pocket

Binding mode characterization of NBD series CD4-mimetic HIV-1 entry inhibitors by X-ray structure and resistance study

Comparative Pharmacokinetics of a Dual Inhibitor of HIV-1, NBD-14189, in Rats and Dogs with a Proof-of-Concept Evaluation of Antiviral Potency in SCID-hu Mouse Model

Conserved salt bridge between the N- and C-terminal heptad repeat regions of the human immunodeficiency virus type 1 gp41 core structure is critical for virus entry and inhibition

Correction to Synthesis, Antiviral Potency, in Vitro ADMET, and X-ray Structure of Potent CD4 Mimics as Entry Inhibitors That Target the Phe43 Cavity of HIV-1 gp120.

Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site

Design of antiviral stapled peptides containing a biphenyl cross-linker

Design, Synthesis, and Antiviral Activity of Entry Inhibitors That Target the CD4-Binding Site of HIV-1 ⬇️

Design, Synthesis, and Biological Activity of Novel 5-((Arylfuran/1H-pyrrol-2-yl)methylene)-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-4-ones as HIV-1 Fusion Inhibitors Targeting gp41 ⬇️

Design, synthesis and evaluation of small molecule CD4-mimics as entry inhibitors possessing broad spectrum anti-HIV-1 activity.

Design, synthesis, and structure-activity relationship of a novel series of 2-aryl 5-(4-oxo-3-phenethyl-2-thioxothiazolidinylidenemethyl)furans as HIV-1 entry inhibitors

Development of Small-molecule HIV Entry Inhibitors Specifically Targeting gp120 or gp41

Dual-acting stapled peptides target both HIV-1 entry and assembly

Identification of Combinations of Protein Kinase C Activators and Histone Deacetylase Inhibitors That Potently Reactivate Latent HIV

Identification of a receptor-binding domain in the S protein of the novel human coronavirus Middle East respiratory syndrome coronavirus as an essential target for vaccine development

Molecular basis of two novel and related high‐prevalence antigens in the Kell blood group system, KUCI and KANT, and their serologic and spatial association with K11 and KETI ⬇️

N-substituted pyrrole derivatives as novel human immunodeficiency virus type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus fusion

Novel anti-HIV peptides containing multiple copies of artificially designed heptad repeat motifs

Novel structures of self-associating stapled peptides

Peptide and non-peptide HIV fusion inhibitors

Preclinical Optimization of gp120 Entry Antagonists as anti-HIV-1 Agents with Improved Cytotoxicity and ADME Properties through Rational Design, Synthesis, and Antiviral Evaluation

Progress in identifying peptides and small-molecule inhibitors targeted to gp41 of HIV-1.

Prospects and strategies for the discovery and development of small-molecule inhibitors of six-helix bundle formation in class 1 viral fusion proteins

Punica granatum (Pomegranate) juice provides an HIV-1 entry inhibitor and candidate topical microbicide

Punica granatum (pomegranate) juice provides an HIV-1 entry inhibitor and candidate topical microbicide.

Putative conformations of the receptor-binding domain in S protein of hCoV-EMC in complex with its receptor dipeptidyl peptidase-4.

Rational Design of HIV-1 Entry Inhibitors ⬇️

Solution Structure of a Hydrocarbon Stapled Peptide Inhibitor in Complex with Monomeric C-terminal Domain of HIV-1 Capsid

Structure-Based Design of a Small Molecule CD4-Antagonist with Broad Spectrum Anti-HIV-1 Activity

Structure-based identification and neutralization mechanism of tyrosine sulfate mimetics that inhibit HIV-1 entry

Synthesis of 2-Oxo-1, 2-Dihydroquinoline Chemotype with Multiple Attachment Points as Novel Screening Compounds for Drug Discovery

Synthesis, Antiviral Activity, and Structure-Activity Relationship of 1,3-Benzodioxolyl Pyrrole-Based Entry Inhibitors Targeting the Phe43 Cavity in HIV-1 gp120

Synthesis, Antiviral Potency, in Vitro ADMET, and X-ray Structure of Potent CD4 Mimics as Entry Inhibitors That Target the Phe43 Cavity of HIV-1 gp120.

Synthesis, antiviral activity and resistance of a novel small molecule HIV-1 entry inhibitor

The conserved residue Arg46 in the N-terminal heptad repeat domain of HIV-1 gp41 is critical for viral fusion and entry

Theaflavin derivatives in black tea and catechin derivatives in green tea inhibit HIV-1 entry by targeting gp41

Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops

Viral inhibition studies on sulfated lignin, a chemically modified biopolymer and a potential mimic of heparan sulfate.

Virtual screening based identification of novel small-molecule inhibitors targeted to the HIV-1 capsid

XTT formazan widely used to detect cell viability inhibits HIV type 1 infection in vitro by targeting gp41.