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A novel mechanism of non-Aβ component of Alzheimer's disease amyloid (NAC) neurotoxicity. Interplay between p53 protein and cyclin-dependent kinase 5 (Cdk5).

artículo científico publicado en 2010

Alpha-synuclein and its neurotoxic fragment inhibit dopamine uptake into rat striatal synaptosomes. Relationship to nitric oxide

artículo científico publicado en 2006

Alpha-synuclein decreases arachidonic acid incorporation into rat striatal synaptoneurosomes

artículo científico publicado en 2007

Alpha-synuclein induced cell death in mouse hippocampal (HT22) cells is mediated by nitric oxide-dependent activation of caspase-3.

artículo científico publicado en 2010

Alpha-synuclein inhibits poly (ADP-ribose) polymerase-1 (PARP-1) activity via NO-dependent pathway.

artículo científico publicado en 2009

Alpha-synuclein potentiates Ca2+ influx through voltage-dependent Ca2+ channels

artículo científico publicado en 2006

Altered Arginine Metabolism in Cells Transfected with Human Wild-Type Beta Amyloid Precursor Protein (βAPP).

artículo científico publicado en 2016

Altered Expression of Urea Cycle Enzymes in Amyloid-β Protein Precursor Overexpressing PC12 Cells and in Sporadic Alzheimer's Disease Brain

artículo científico publicado en 2018

Alzheimer's disease related peptides affected cholinergic receptor mediated poly(ADP-ribose) polymerase activity in the hippocampus.

artículo científico publicado en 2005

Assessment of antioxidative activity of alkaloids from Huperzia selago and Diphasiastrum complanatum using in vitro systems

artículo científico publicado en 2014

Cdk5 at crossroads of protein oligomerization in neurodegenerative diseases: facts and hypotheses

artículo científico

Copper Dyshomeostasis in Neurodegenerative Diseases-Therapeutic Implications

scientific article published on 04 December 2020

Dysfunctional proteins in neuropsychiatric disorders: from neurodegeneration to Autism Spectrum Disorders

artículo científico publicado en 2020

Effect of N-methyl-D-aspartate (NMDA) receptor antagonists on alpha-synuclein-evoked neuronal nitric oxide synthase activation in the rat brain.

artículo científico publicado en 2009

Effect of aging and oxidative/genotoxic stress on poly(ADP-ribose) polymerase-1 activity in rat brain

scientific journal article

Expression and activity of PARP family members in the hippocampus during systemic inflammation: their role in the regulation of prooxidative genes

artículo científico publicado en 2013

Extracellular Alpha-Synuclein Oligomers Induce Parkin S-Nitrosylation: Relevance to Sporadic Parkinson's Disease Etiopathology.

artículo científico publicado en 2018

Extracellular alpha-synuclein induces calpain-dependent overactivation of cyclin-dependent kinase 5 in vitro.

artículo científico publicado en 2013

Extracellular α-synuclein leads to microtubule destabilization via GSK-3β-dependent Tau phosphorylation in PC12 cells

artículo científico publicado en 2014

Fatal Acute Respiratory Distress Syndrome Due to Influenza A (H1N1) Infection in Patients After Kidney Transplantation: A Report of Five Cases.

artículo científico publicado en 2018

GSK-3beta and oxidative stress in aged brain. Role of poly(ADP- -ribose) polymerase-1.

artículo científico publicado en 2007

Inhibition of cyclin-dependent kinase 5 affects early neuroinflammatory signalling in murine model of amyloid beta toxicity.

artículo científico publicado en 2018

Inhibition of mitochondrial complex II affects dopamine metabolism and decreases its uptake into striatal synaptosomes

artículo científico publicado en 2006

Maternal Immune Activation Induces Neuroinflammation and Cortical Synaptic Deficits in the Adolescent Rat Offspring

scientific article published on 08 June 2020

New definition of ventilator associated pneumonia might not necessarily have been a step in the right direction. Key takeaways from published studies after two years in clinical use

artículo científico publicado en 2015

P2X7 Receptor is Involved in Mitochondrial Dysfunction Induced by Extracellular Alpha Synuclein in Neuroblastoma SH-SY5Y Cells

scientific article published on 31 May 2020

P2X7 receptor-pannexin 1 interaction mediates extracellular alpha-synuclein-induced ATP release in neuroblastoma SH-SY5Y cells

artículo científico publicado en 2017

Perinatal exposure to lead (Pb) induces ultrastructural and molecular alterations in synapses of rat offspring

artículo científico publicado en 2016

Perinatal exposure to lead (Pb) promotes Tau phosphorylation in the rat brain in a GSK-3β and CDK5 dependent manner: Relevance to neurological disorders

artículo científico publicado en 2016

Phosphatidylinositol transfer protein expression altered by aging and Parkinson disease.

artículo científico publicado en 2006

Poly(ADP-ribose) polymerase-1 in amyloid beta toxicity and Alzheimer's disease.

artículo científico

Prenatal Exposure to Valproic Acid Affects Microglia and Synaptic Ultrastructure in a Brain-Region-Specific Manner in Young-Adult Male Rats: Relevance to Autism Spectrum Disorders

scientific article published on 18 May 2020

Protective Effects of Selol Against Sodium Nitroprusside-Induced Cell Death and Oxidative Stress in PC12 Cells

artículo científico publicado en 2016

Selenium in the Therapy of Neurological Diseases. Where is it Going?

artículo científico publicado en 2015

Selol, an organic selenium donor, prevents lipopolysaccharide-induced oxidative stress and inflammatory reaction in the rat brain.

artículo científico publicado en 2017

The interplay between parkin and alpha-synuclein; possible implications for the pathogenesis of Parkinson's disease

artículo científico publicado en 2019

The mechanisms regulating cyclin-dependent kinase 5 in hippocampus during systemic inflammatory response: The effect on inflammatory gene expression.

artículo científico publicado en 2016

Toxicity of extracellular secreted alpha-synuclein: Its role in nitrosative stress and neurodegeneration

artículo científico publicado en 2013

Treatments and compositions targeting α-synuclein: a patent review (2010-2016).

artículo científico publicado en 2016

[The role of extracellular α-synuclein in molecular mechanisms of cell death]

artículo científico publicado en 2013

alpha-Synuclein enhances secretion and toxicity of amyloid beta peptides in PC12 cells.

artículo científico publicado en 2008