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Acetic Acid Mediated for One-Pot Synthesis of Novel Pyrazolyl -Triazine Derivatives for the Targeted Therapy of Triple-Negative Breast Tumor Cells (MDA-MB-231) EGFR/PI3K/AKT/mTOR Signaling Cascades

Antimicrobial and antiproliferative activities of novel synthesized 6-(quinolin-2-ylthio) pyridine derivatives with molecular docking study as multi-targeted JAK2/STAT3 inhibitors

scientific article published on 12 September 2020

Auspicious role of the steroidal heterocyclic derivatives as a platform for anti-cancer drugs.

artículo científico publicado en 2017

Chemical Profiling, Antioxidant, Cytotoxic Activities and Molecular Docking Simulation of <i>Carrichtera annua</i> DC. (Cruciferae)

artículo científico publicado en 2020

Cytotoxic, Apoptosis-Inducing Activities, and Molecular Docking of a New Sterol from Bamboo Shoot Skin <i>Phyllostachys heterocycla</i> var. pubescens

scientific article published on 30 November 2020

Micromonospora species from rarely-exploited Egyptian habitats: chemical profile, antimicrobial, and antitumor activities through antioxidant property

artículo científico publicado en 2021

Molecular Insights into Human Transmembrane Protease Serine-2 (TMPS2) Inhibitors against SARS-CoV2: Homology Modelling, Molecular Dynamics, and Docking Studies

artículo científico publicado en 2020

Molecular docking, anti-proliferative activity and induction of apoptosis in human liver cancer cells treated with androstane derivatives: Implication of PI3K/AKT/mTOR pathway

scientific article published on 23 January 2020

Phragmanthera austroarabica A.G.Mill. and J.A.Nyberg Triggers Apoptosis in MDA-MB-231 Cells In Vitro and In Vivo Assays: Simultaneous Determination of Selected Constituents

artículo científico publicado en 2022

Screening of different drug design tools to predict the mode of action of steroidal derivatives as anti-cancer agents

scientific article published on 03 September 2019

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)--triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades

Synthesis, 3D-QSAR, and Molecular Modeling Studies of Triazole Bearing Compounds as a Promising Scaffold for Cyclooxygenase-2 Inhibition

scientific article published on 06 November 2020

Synthesis, molecular modeling and anti-cancer evaluation of a series of quinazoline derivatives

scientific article published on 07 October 2019