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4,5,6,7-Tetrahydro-isoxazolo-[4,5-c]-pyridines as a new class of cytotoxic Hsp90 inhibitors

artículo científico publicado en 2014

A convenient synthesis of unsymmetrically substituted terphenyls of biologically active stilbenes via a double Suzuki cross-coupling protocol

A novel hybrid drug between two potent anti-tubulin agents as a potential prolonged anticancer approach

artículo científico publicado en 2016

Antitumor effects of curcumin and structurally beta-diketone modified analogs on multidrug resistant cancer cells.

artículo científico publicado en 2007

Arylamidonaphtalene sulfonate compounds as a novel class of heparanase inhibitors

artículo científico publicado en 2017

Curcumin as a possible lead compound against hormone-independent, multidrug-resistant breast cancer.

artículo científico publicado en 2009

Design, synthesis and biological evaluation of novel stilbene-based antitumor agents.

artículo científico publicado en 2008

Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a gammadelta-T lymphocytes-mediated activation mechanism.

artículo científico publicado en 2008

Development of hemiasterlin derivatives as potential anticancer agents that inhibit tubulin polymerization and synergize with a stilbene tubulin inhibitor.

artículo científico publicado en 2011

Effects of Pimozide Derivatives on pSTAT5 in K562 Cells.

artículo científico publicado en 2017

Facile synthesis of 2-nitroalkanols by tetramethylguanidine (TMG)-catalyzed addition of primary nitroalkanes to aldehydes and alicyclic ketones

article

Galangin increases the cytotoxic activity of imatinib mesylate in imatinib-sensitive and imatinib-resistant Bcr-Abl expressing leukemia cells

artículo científico publicado en 2008

Hemiasterlin derivative (R)(S)(S)-BF65 and Akt inhibitor MK-2206 synergistically inhibit SKOV3 ovarian cancer cell growth

artículo científico publicado en 2016

Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines.

artículo científico publicado en 2005

Hydropathic analysis and biological evaluation of stilbene derivatives as colchicine site microtubule inhibitors with anti-leukemic activity

artículo científico publicado en 2009

Inhibition of activated STAT5 in Bcr/Abl expressing leukemia cells with new pimozide derivatives

artículo científico publicado en 2014

Lack of nucleophilic addition in the isoxazole and pyrazole diketone modified analogs of curcumin; implications for their antitumor and chemosensitizing activities

artículo científico publicado en 2009

Novel 3,4-Isoxazolediamides as Potent Inhibitors of Chaperone Heat Shock Protein 90

artículo científico publicado el 23 de noviembre de 2011

Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity.

artículo científico publicado en 2008

Novel combretastatin analogues endowed with antitumor activity

artículo científico publicado en 2006

Novel terphenyls and 3,5-diaryl isoxazole derivatives endowed with growth supporting and antiapoptotic properties.

artículo científico publicado en 2008

Pro-apoptotic activity of novel synthetic isoxazole derivatives exhibiting inhibitory activity against tumor cell growth in vitro

scientific article published on 24 August 2020

Stilbene-based anticancer agents: resveratrol analogues active toward HL60 leukemic cells with a non-specific phase mechanism

artículo científico publicado en 2006

Studies on the apoptotic activity of natural and synthetic retinoids: discovery of a new class of synthetic terphenyls that potently support cell growth and inhibit apoptosis in neuronal and HL-60 cells.

artículo científico publicado en 2005

Synthesis and biological activity of a novel class nicotinic acetylcholine receptors (nAChRs) ligands structurally related to anatoxin-a

artículo científico publicado en 2011

Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents

artículo científico publicado en 2003

Synthesis and pharmacology of 6-substituted benztropines: discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporter

artículo científico publicado en 2005

The antitumor activities of curcumin and of its isoxazole analogue are not affected by multiple gene expression changes in an MDR model of the MCF-7 breast cancer cell line: analysis of the possible molecular basis.

artículo científico publicado en 2007

Versatile synthesis of new cytotoxic agents structurally related to hemiasterlins

artículo científico publicado en 2010