Lista de obras -

A Nucleosome Bridging Mechanism for Activation of a Maintenance DNA Methyltransferase

artículo científico publicado en 2018

A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly

artículo científico publicado en 2013

A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation

artículo científico publicado en 2015

A nucleotide-driven switch regulates flanking DNA length sensing by a dimeric chromatin remodeler

artículo científico publicado en 2015

A proposal for kinetic proof reading by ISWI family chromatin remodeling motors ⬇️

artículo científico publicado el 15 de septiembre de 2010

ATP-dependent chromatin remodeling enzymes: two heads are not better, just different

artículo científico publicado en 2008

ATP-dependent remodeling and acetylation as regulators of chromatin fluidity

artículo científico publicado en 1999

Analysis of Changes in Nucleosome Conformation Using Fluorescence Resonance Energy Transfer ⬇️

artículo científico publicado el 1 de enero de 2012

Analysis of Nucleosome Sliding by ATP-Dependent Chromatin Remodeling Enzymes

artículo científico publicado en 2016

Biochemical Basis for Distinct Roles of the Heterochromatin Proteins Swi6 and Chp2.

artículo científico publicado en 2017

Biophysical Properties of HP1-Mediated Heterochromatin

scientific article published on 03 June 2020

Characterization of a local folding event of the Tetrahymena group I ribozyme: effects of oligonucleotide substrate length, pH, and temperature on the two substrate binding steps

artículo científico publicado en 1999

Chromatin remodelers act globally, sequence positions nucleosomes locally

artículo científico publicado en 2009

Chromatin topology, condensates and gene regulation: shifting paradigms or just a phase?

scientific article published on 25 September 2019

Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly.

artículo científico publicado en 2011

Cooperation between complexes that regulate chromatin structure and transcription

artículo científico publicado en 2002

Cryo-EM structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome

artículo científico publicado en 2019

Direct Demonstration of the Catalytic Role of Binding Interactions in an Enzymatic Reaction ⬇️

artículo científico publicado el 14 de julio de 1998

Dissection of the role of the conserved G.U pair in group I RNA self-splicing

artículo científico publicado en 1994

Distinct strategies to make nucleosomal DNA accessible

artículo científico publicado en 2003

Distortion of histone octamer core promotes nucleosome mobilization by a chromatin remodeler

artículo científico publicado en 2017

Division of labor between the chromodomains of HP1 and Suv39 methylase enables coordination of heterochromatin spread.

artículo científico publicado en 2013

Dynamics of nucleosome remodelling by individual ACF complexes

artículo científico publicado en 2009

Enzymatic Reactions inside Biological Condensates

scientific article published on 14 August 2020

Epigenomics: a roadmap, but to where?

artículo científico publicado en 2008

Ers1 links HP1 to RNAi ⬇️

artículo científico publicado el 25 de junio de 2012

Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase

artículo científico publicado en 2020

Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase

artículo científico publicado en 2020

FRET-based methods to study ATP-dependent changes in chromatin structure

artículo científico publicado en 2007

Functional differences between the human ATP-dependent nucleosome remodeling proteins BRG1 and SNF2H

artículo científico publicado en 2001

Generation and Interconversion of Multiple Distinct Nucleosomal States as a Mechanism for Catalyzing Chromatin Fluidity ⬇️

artículo científico publicado el 1 de diciembre de 2001

HP1 reshapes nucleosome core to promote phase separation of heterochromatin

scientific article published on 16 October 2019

Heterogeneous nuclear ribonucleoprotein C1/C2, MeCP1, and SWI/SNF form a chromatin remodeling complex at the beta-globin locus control region

artículo científico publicado en 2005

Human ACF1 alters the remodeling strategy of SNF2h

scientific article published on 29 July 2006

Ion counting demonstrates a high electrostatic field generated by the nucleosome.

artículo científico publicado en 2019

Ion counting demonstrates a high electrostatic potential of the nucleosome

Isolation of a local tertiary folding transition in the context of a globally folded RNA.

artículo científico publicado en 1996

Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin.

artículo científico publicado en 2017

Liquid-like interactions in heterochromatin: Implications for mechanism and regulation

artículo científico publicado en 2020

MacroH2A allows ATP-dependent chromatin remodeling by SWI/SNF and ACF complexes but specifically reduces recruitment of SWI/SNF.

artículo científico publicado en 2008

Massively multiplex single-molecule oligonucleosome footprinting

artículo científico publicado en 2020

Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes

artículo científico

Mechanisms of ATP-Dependent Chromatin Remodeling Motors

artículo científico publicado en 2016

Mechanisms of functional promiscuity by HP1 proteins

artículo científico publicado en 2014

Mechanistic aspects of enzymatic catalysis: lessons from comparison of RNA and protein enzymes

artículo científico publicado en 1997

Noncovalent modification of chromatin: different remodeled products with different ATPase domains

artículo científico publicado en 2004

Nucleosome breathing and remodeling constrain CRISPR-Cas9 function

artículo científico publicado en 2016

Nucleosome remodeling by the human SWI/SNF complex requires transient global disruption of histone-DNA interactions

artículo científico publicado en 2002

Phase-separation in chromatin organization

scientific article published on 01 January 2020

Protonated 2'-aminoguanosine as a probe of the electrostatic environment of the active site of the Tetrahymena group I ribozyme

artículo científico publicado en 1999

Quantitating tertiary binding energies of 2' OH groups on the P1 duplex of the Tetrahymena ribozyme: intrinsic binding energy in an RNA enzyme

artículo científico

Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits

artículo científico publicado en 1999

Reconstitution of nucleosome demethylation and catalytic properties of a Jumonji histone demethylase.

artículo científico publicado en 2013

Regulation of Rvb1/Rvb2 by a Domain within the INO80 Chromatin Remodeling Complex Implicates the Yeast Rvbs as Protein Assembly Chaperones

artículo científico publicado en 2017

Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility

artículo científico publicado en 2023

Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes

artículo científico publicado en 2001

Site-specific acetylation mark on an essential chromatin-remodeling complex promotes resistance to replication stress

artículo científico publicado en 2011

Stability of a human SWI-SNF remodeled nucleosomal array

artículo científico publicado en 2001

Stable remodeling of tailless nucleosomes by the human SWI-SNF complex

artículo científico publicado en 1999

Structural Basis of Silencing: Sir3 BAH Domain in Complex with a Nucleosome at 3.0 Å Resolution ⬇️

artículo científico publicado el 18 de noviembre de 2011

The ATP-Dependent Remodeler RSC Transfers Histone Dimers and Octamers through the Rapid Formation of an Unstable Encounter Intermediate ⬇️

artículo científico publicado el 25 de octubre de 2010

The Role of Phase Separation in Heterochromatin Formation, Function, and Regulation

artículo científico publicado en 2018

The Yeast INO80 Complex Operates as a Tunable DNA Length-Sensitive Switch to Regulate Nucleosome Sliding.

artículo científico publicado en 2018

The chromatin remodeller ACF acts as a dimeric motor to space nucleosomes

artículo científico publicado en 2009

The chromatin-remodeling enzyme ACF is an ATP-dependent DNA length sensor that regulates nucleosome spacing

artículo científico publicado en 2006

The histone H4 tail regulates the conformation of the ATP-binding pocket in the SNF2h chromatin remodeling enzyme

artículo científico publicado en 2014

The nucleosomal acidic patch relieves auto-inhibition by the ISWI remodeler SNF2h.

artículo científico publicado en 2018

The site-specific installation of methyl-lysine analogs into recombinant histones

artículo científico publicado en 2007

Topical collection on Chromatin Biology and Epigenetics

scientific article published on 01 January 2020

Use of binding energy by an RNA enzyme for catalysis by positioning and substrate destabilization

artículo científico publicado en 1995

Use of duplex rigidity for stability and specificity in RNA tertiary structure

artículo científico

Visualization and Quantitation of Phase-Separated Droplet Formation by Human HP1α

artículo científico publicado en 2018

Zscan4 binds nucleosomal microsatellite DNA and protects mouse two-cell embryos from DNA damage

scientific article published on 20 March 2020

Lista de obras de

A Nucleosome Bridging Mechanism for Activation of a Maintenance DNA Methyltransferase

A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly

A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation

A nucleotide-driven switch regulates flanking DNA length sensing by a dimeric chromatin remodeler

A proposal for kinetic proof reading by ISWI family chromatin remodeling motors ⬇️

ATP-dependent chromatin remodeling enzymes: two heads are not better, just different

ATP-dependent remodeling and acetylation as regulators of chromatin fluidity

Analysis of Changes in Nucleosome Conformation Using Fluorescence Resonance Energy Transfer ⬇️

Analysis of Nucleosome Sliding by ATP-Dependent Chromatin Remodeling Enzymes

Biochemical Basis for Distinct Roles of the Heterochromatin Proteins Swi6 and Chp2.

Biophysical Properties of HP1-Mediated Heterochromatin

Characterization of a local folding event of the Tetrahymena group I ribozyme: effects of oligonucleotide substrate length, pH, and temperature on the two substrate binding steps

Chromatin remodelers act globally, sequence positions nucleosomes locally

Chromatin topology, condensates and gene regulation: shifting paradigms or just a phase?

Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly.

Cooperation between complexes that regulate chromatin structure and transcription

Cryo-EM structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome

Direct Demonstration of the Catalytic Role of Binding Interactions in an Enzymatic Reaction ⬇️

Dissection of the role of the conserved G.U pair in group I RNA self-splicing

Distinct strategies to make nucleosomal DNA accessible

Distortion of histone octamer core promotes nucleosome mobilization by a chromatin remodeler

Division of labor between the chromodomains of HP1 and Suv39 methylase enables coordination of heterochromatin spread.

Dynamics of nucleosome remodelling by individual ACF complexes

Enzymatic Reactions inside Biological Condensates

Epigenomics: a roadmap, but to where?

Ers1 links HP1 to RNAi ⬇️

Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase

Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase

FRET-based methods to study ATP-dependent changes in chromatin structure

Functional differences between the human ATP-dependent nucleosome remodeling proteins BRG1 and SNF2H

Generation and Interconversion of Multiple Distinct Nucleosomal States as a Mechanism for Catalyzing Chromatin Fluidity ⬇️

HP1 reshapes nucleosome core to promote phase separation of heterochromatin

Heterogeneous nuclear ribonucleoprotein C1/C2, MeCP1, and SWI/SNF form a chromatin remodeling complex at the beta-globin locus control region

Human ACF1 alters the remodeling strategy of SNF2h

Ion counting demonstrates a high electrostatic field generated by the nucleosome.

Ion counting demonstrates a high electrostatic potential of the nucleosome

Isolation of a local tertiary folding transition in the context of a globally folded RNA.

Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin.

Liquid-like interactions in heterochromatin: Implications for mechanism and regulation

MacroH2A allows ATP-dependent chromatin remodeling by SWI/SNF and ACF complexes but specifically reduces recruitment of SWI/SNF.

Massively multiplex single-molecule oligonucleosome footprinting

Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes

Mechanisms of ATP-Dependent Chromatin Remodeling Motors

Mechanisms of functional promiscuity by HP1 proteins

Mechanistic aspects of enzymatic catalysis: lessons from comparison of RNA and protein enzymes

Noncovalent modification of chromatin: different remodeled products with different ATPase domains

Nucleosome breathing and remodeling constrain CRISPR-Cas9 function

Nucleosome remodeling by the human SWI/SNF complex requires transient global disruption of histone-DNA interactions

Phase-separation in chromatin organization

Protonated 2'-aminoguanosine as a probe of the electrostatic environment of the active site of the Tetrahymena group I ribozyme

Quantitating tertiary binding energies of 2' OH groups on the P1 duplex of the Tetrahymena ribozyme: intrinsic binding energy in an RNA enzyme

Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits

Reconstitution of nucleosome demethylation and catalytic properties of a Jumonji histone demethylase.

Regulation of Rvb1/Rvb2 by a Domain within the INO80 Chromatin Remodeling Complex Implicates the Yeast Rvbs as Protein Assembly Chaperones

Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility

Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes

Site-specific acetylation mark on an essential chromatin-remodeling complex promotes resistance to replication stress

Stability of a human SWI-SNF remodeled nucleosomal array

Stable remodeling of tailless nucleosomes by the human SWI-SNF complex

Structural Basis of Silencing: Sir3 BAH Domain in Complex with a Nucleosome at 3.0 Å Resolution ⬇️

The ATP-Dependent Remodeler RSC Transfers Histone Dimers and Octamers through the Rapid Formation of an Unstable Encounter Intermediate ⬇️

The Role of Phase Separation in Heterochromatin Formation, Function, and Regulation

The Yeast INO80 Complex Operates as a Tunable DNA Length-Sensitive Switch to Regulate Nucleosome Sliding.

The chromatin remodeller ACF acts as a dimeric motor to space nucleosomes

The chromatin-remodeling enzyme ACF is an ATP-dependent DNA length sensor that regulates nucleosome spacing

The histone H4 tail regulates the conformation of the ATP-binding pocket in the SNF2h chromatin remodeling enzyme

The nucleosomal acidic patch relieves auto-inhibition by the ISWI remodeler SNF2h.

The site-specific installation of methyl-lysine analogs into recombinant histones

Topical collection on Chromatin Biology and Epigenetics

Use of binding energy by an RNA enzyme for catalysis by positioning and substrate destabilization

Use of duplex rigidity for stability and specificity in RNA tertiary structure

Visualization and Quantitation of Phase-Separated Droplet Formation by Human HP1α

Zscan4 binds nucleosomal microsatellite DNA and protects mouse two-cell embryos from DNA damage