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AP-2alpha knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis

scientific journal article

AP-2α is required after lens vesicle formation to maintain lens integrity

artículo científico publicado en 2014

AP-2β Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development.

artículo científico publicado en 2016

AP-2β is required for formation of the murine trabecular meshwork and Schlemm's canal

scientific article published on 27 April 2020

Aberrant Collagen Composition of the Trabecular Meshwork Results in Reduced Aqueous Humor Drainage and Elevated IOP in MMP-9 Null Mice

artículo científico publicado en 2016

Activation of the hedgehog signaling pathway in the developing lens stimulates ectopic FoxE3 expression and disruption in fiber cell differentiation

artículo científico publicado en 2012

Activity and expression of Xenopus laevis matrix metalloproteinases: identification of a novel role for the hormone prolactin in regulating collagenolysis in both amphibians and mammals

artículo científico publicado en 2004

Adenoviral gene transfer of bioactive TGFbeta1 to the rodent eye as a novel model for anterior subcapsular cataract

artículo científico publicado en 2007

Altered expression of transforming growth factor beta 1 and matrix metalloproteinase-9 results in elevated intraocular pressure in mice

artículo científico publicado el 21 de marzo de 2013

Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype

scientific journal article

Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival

artículo científico publicado en 2008

Conditional Deletion of AP-2α and AP-2β in the Developing Murine Retina Leads to Altered Amacrine Cell Mosaics and Disrupted Visual Function.

artículo científico publicado en 2018

Conditional deletion of AP-2β in mouse cranial neural crest results in anterior segment dysgenesis and early-onset glaucoma

artículo científico publicado en 2016

Conditional deletion of activating protein 2alpha (AP-2alpha) in the developing retina demonstrates non-cell-autonomous roles for AP-2alpha in optic cup development

scientific journal article

Corneal development: Role of the periocular mesenchyme and Bi-directional signaling

artículo científico publicado en 2020

Corneal epithelial cell adhesion and growth on EGF-modified aminated PDMS

artículo científico publicado en 2010

Development and use of the lens epithelial explant system to study lens differentiation and cataractogenesis

scientific article published on 17 December 2009

Differential regulation of components of the ubiquitin-proteasome pathway during lens cell differentiation

artículo científico publicado en 2004

Dual function of TGFβ in lens epithelial cell fate: implications for secondary cataract.

artículo científico publicado en 2017

Ectopic expression of AP-2alpha transcription factor in the lens disrupts fiber cell differentiation

artículo científico publicado en 2002

Genetic analysis indicates that transcription factors AP-2alpha and Pax6 cooperate in the normal patterning and morphogenesis of the lens

artículo científico publicado en 2007

Lens-specific expression of TGF-beta induces anterior subcapsular cataract formation in the absence of Smad3

artículo científico publicado en 2006

Matrix Metalloproteinases as Mediators of Primary and Secondary Cataracts

artículo científico publicado en 2007

Matrix metalloproteinase 9 is associated with peritoneal membrane solute transport and induces angiogenesis through β-catenin signaling

artículo científico publicado en 2016

Matrix metalloproteinase inhibitors suppress transforming growth factor-beta-induced subcapsular cataract formation

artículo científico publicado en 2006

Matrix metalloproteinase-9-null mice are resistant to TGF-β-induced anterior subcapsular cataract formation

artículo científico publicado en 2014

Nuclear translocation of myocardin-related transcription factor-A during transforming growth factor beta-induced epithelial to mesenchymal transition of lens epithelial cells

artículo científico publicado el 6 de mayo de 2013

Ocular gene transfer of active TGF-beta induces changes in anterior segment morphology and elevated IOP in rats

artículo científico publicado en 2009

Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina

artículo científico publicado en 2012

Positive influence of AP-2alpha transcription factor on cadherin gene expression and differentiation of the ocular surface

artículo científico publicado en 2003

Relationship between neural crest cell specification and rare ocular diseases.

artículo científico publicado en 2018

RhoA/ROCK signaling regulates TGFβ-induced epithelial-mesenchymal transition of lens epithelial cells through MRTF-A

artículo científico publicado en 2016

Targeted deletion of AP-2alpha leads to disruption in corneal epithelial cell integrity and defects in the corneal stroma

scientific journal article

Temporal changes in MMP mRNA expression in the lens epithelium during anterior subcapsular cataract formation

artículo científico publicado en 2008

The keratocyte: corneal stromal cell with variable repair phenotypes

artículo científico publicado en 2006

The role of Hsp70 and Hsp90 in TGF-beta-induced epithelial-to-mesenchymal transition in rat lens epithelial explants

scientific article published on 29 November 2007

Transcription Factors Pax6 and AP-2alpha Interact To Coordinate Corneal Epithelial Repair by Controlling Expression of Matrix Metalloproteinase Gelatinase B

artículo científico publicado en 2004

Transient overexpression of TGF-{beta}1 induces epithelial mesenchymal transition in the rodent peritoneum

artículo científico publicado en 2004

β-Catenin/CBP-Dependent Signaling Regulates TGF-β-Induced Epithelial to Mesenchymal Transition of Lens Epithelial Cells

artículo científico publicado en 2016

β-Catenin/Smad3 Interaction Regulates Transforming Growth Factor-β-Induced Epithelial to Mesenchymal Transition in the Lens

artículo científico publicado en 2019