Lista de obras -

A comprehensive survey of DNA-binding transcription factor gene expression in human fetal and adult organs.

artículo científico publicado en 2006

A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling

artículo científico publicado en 2008

Accumulation of the predominant pancreatic mRNAs during embryonic development ⬇️

artículo científico publicado el 25 de marzo de 1979

An Endocrine-Exocrine Switch in the Activity of the Pancreatic Homeodomain Protein PDX1 through Formation of a Trimeric Complex with PBX1b and MRG1 (MEIS2) ⬇️

artículo científico publicado el 1 de septiembre de 1998

An endocrine-specific element is an integral component of an exocrine-specific pancreatic enhancer ⬇️

artículo científico publicado el 1 de mayo de 1993

An inflammatory transcriptional switch

artículo científico publicado en 2018

Concerted cell and in vivo screen for pancreatic ductal adenocarcinoma (PDA) chemotherapeutics

scientific article published on 26 November 2020

Conditional control of the differentiation competence of pancreatic endocrine and ductal cells by Fgf10.

artículo científico publicado en 2009

Conditional expression demonstrates the role of the homeodomain transcription factor Pdx1 in maintenance and regeneration of beta-cells in the adult pancreas

artículo científico publicado en 2005

Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus

artículo científico publicado en 2006

Diagnostic and Prognostic Markers for Pancreatitis and Pancreatic Ductal Adenocarcinoma

artículo científico publicado en 2024

Dominant and context-specific control of endodermal organ allocation by Ptf1a ⬇️

artículo científico publicado en 2014

Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex

scientific journal article

Experimental control of pancreatic development and maintenance

artículo científico publicado en 2002

Induced Mist1 expression promotes remodeling of mouse pancreatic acinar cells

artículo científico publicado en 2012

Isolated Pancreatic Aplasia Due to a Hypomorphic PTF1A Mutation.

artículo científico publicado en 2016

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease ⬇️

artículo científico publicado el 27 de noviembre de 1979

LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function.

artículo científico publicado en 2011

MIST1 Links Secretion and Stress as Both Target and Regulator of the UPR.

artículo científico publicado en 2016

MIST1 and PTF1 Collaborate in Feed-forward Regulatory Loops that Maintain the Pancreatic Acinar Phenotype in Adult Mice.

artículo científico publicado en 2016

Multiple transcriptional mechanisms control Ptf1a levels during neural development including autoregulation by the PTF1-J complex

artículo científico publicado en 2009

Neurog2 is a direct downstream target of the Ptf1a-Rbpj transcription complex in dorsal spinal cord

artículo científico publicado en 2009

Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas

artículo científico publicado en 2004

Notch-independent functions of CSL.

artículo científico publicado en 2011

Notch-mediated patterning and cell fate allocation of pancreatic progenitor cells

artículo científico publicado en 2012

PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression

artículo científico publicado en 2009

PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L.

artículo científico publicado en 2006

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

artículo científico publicado en 2012

Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and mice

artículo científico publicado en 2012

Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism

artículo científico publicado en 2019

Prevention and reversion of pancreatic tumorigenesis through a differentiation-based mechanism

artículo científico publicado en 2017

Program specificity for Ptf1a in pancreas versus neural tube development correlates with distinct collaborating cofactors and chromatin accessibility

artículo científico publicado en 2013

Ptf1a determines GABAergic over glutamatergic neuronal cell fate in the spinal cord dorsal horn

artículo científico publicado en 2005

Ptf1a determines horizontal and amacrine cell fates during mouse retinal development

scientific journal article

Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism ⬇️

artículo científico publicado el 17 de noviembre de 2011

Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells

artículo científico publicado en 2010

Signaling and transcriptional control of pancreatic organogenesis

artículo científico publicado en 2002

Structure of a family of rat amylase genes ⬇️

artículo científico publicado el 11 de septiembre de 1980

Structure of the two related elastase genes expressed in the rat pancreas ⬇️

artículo científico publicado el 25 de noviembre de 1984

Structure of two related rat pancreatic trypsin genes ⬇️

artículo científico publicado el 25 de noviembre de 1984

Synthesis of single-stranded hybridization probes from reusable DNA templates bound to solid support ⬇️

artículo científico publicado el 1 de julio de 1984

The Parahox gene Pdx1 is required to maintain positional identity in the adult foregut

artículo científico publicado en 2013

The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma

artículo científico publicado en 2015

The homeodomain protein PDX1 is required at mid-pancreatic development for the formation of the exocrine pancreas

scientific journal article

The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis

scientific journal article

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

artículo científico publicado en 2002

Transcriptional Control of Acinar Development and Homeostasis

artículo científico publicado el 1 de enero de 2010

Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A.

artículo científico publicado en 2016

Transcriptional autoregulation controls pancreatic Ptf1a expression during development and adulthood

artículo científico publicado en 2008

Transgenic expression of pancreatic secretory trypsin inhibitor-I ameliorates secretagogue-induced pancreatitis in mice

scientific journal article

Lista de obras de

A comprehensive survey of DNA-binding transcription factor gene expression in human fetal and adult organs.

A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling

Accumulation of the predominant pancreatic mRNAs during embryonic development ⬇️

An Endocrine-Exocrine Switch in the Activity of the Pancreatic Homeodomain Protein PDX1 through Formation of a Trimeric Complex with PBX1b and MRG1 (MEIS2) ⬇️

An endocrine-specific element is an integral component of an exocrine-specific pancreatic enhancer ⬇️

An inflammatory transcriptional switch

Concerted cell and in vivo screen for pancreatic ductal adenocarcinoma (PDA) chemotherapeutics

Conditional control of the differentiation competence of pancreatic endocrine and ductal cells by Fgf10.

Conditional expression demonstrates the role of the homeodomain transcription factor Pdx1 in maintenance and regeneration of beta-cells in the adult pancreas

Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus

Diagnostic and Prognostic Markers for Pancreatitis and Pancreatic Ductal Adenocarcinoma

Dominant and context-specific control of endodermal organ allocation by Ptf1a ⬇️

Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex

Experimental control of pancreatic development and maintenance

Induced Mist1 expression promotes remodeling of mouse pancreatic acinar cells

Isolated Pancreatic Aplasia Due to a Hypomorphic PTF1A Mutation.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease ⬇️

LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function.

MIST1 Links Secretion and Stress as Both Target and Regulator of the UPR.

MIST1 and PTF1 Collaborate in Feed-forward Regulatory Loops that Maintain the Pancreatic Acinar Phenotype in Adult Mice.

Multiple transcriptional mechanisms control Ptf1a levels during neural development including autoregulation by the PTF1-J complex

Neurog2 is a direct downstream target of the Ptf1a-Rbpj transcription complex in dorsal spinal cord

Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas

Notch-independent functions of CSL.

Notch-mediated patterning and cell fate allocation of pancreatic progenitor cells

PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression

PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L.

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and mice

Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism

Prevention and reversion of pancreatic tumorigenesis through a differentiation-based mechanism

Program specificity for Ptf1a in pancreas versus neural tube development correlates with distinct collaborating cofactors and chromatin accessibility

Ptf1a determines GABAergic over glutamatergic neuronal cell fate in the spinal cord dorsal horn

Ptf1a determines horizontal and amacrine cell fates during mouse retinal development

Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism ⬇️

Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells

Signaling and transcriptional control of pancreatic organogenesis

Structure of a family of rat amylase genes ⬇️

Structure of the two related elastase genes expressed in the rat pancreas ⬇️

Structure of two related rat pancreatic trypsin genes ⬇️

Synthesis of single-stranded hybridization probes from reusable DNA templates bound to solid support ⬇️

The Parahox gene Pdx1 is required to maintain positional identity in the adult foregut

The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma

The homeodomain protein PDX1 is required at mid-pancreatic development for the formation of the exocrine pancreas

The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

Transcriptional Control of Acinar Development and Homeostasis

Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A.

Transcriptional autoregulation controls pancreatic Ptf1a expression during development and adulthood

Transgenic expression of pancreatic secretory trypsin inhibitor-I ameliorates secretagogue-induced pancreatitis in mice