Filtros de búsqueda

Lista de obras de Patricia B Munroe

52 Genetic Loci Influencing Myocardial Mass

artículo científico publicado en 2016

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

artículo científico publicado en 2018

A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering

artículo científico publicado en 2016

A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium

artículo científico publicado en 2016

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

artículo científico publicado en 2016

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

Advances in blood pressure genomics

artículo científico

Adverse cardiovascular magnetic resonance phenotypes are associated with greater likelihood of incident coronavirus disease 2019: findings from the UK Biobank

artículo científico publicado en 2021

Analysis with the exome array identifies multiple new independent variants in lipid loci

artículo científico publicado en 2016

Artificial intelligence and machine learning to fight COVID-19

scientific article published on 27 March 2020

Association Between Ambient Air Pollution and Cardiac Morpho-Functional Phenotypes: Insights From the UK Biobank Population Imaging Study

artículo científico publicado en 2018

Association of WNK1 gene polymorphisms and haplotypes with ambulatory blood pressure in the general population

artículo científico publicado en 2005

Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals

artículo científico publicado en 2011

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

artículo científico publicado en 2007

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Biological, clinical and population relevance of 95 loci for blood lipids

artículo científico publicado en 2010

Blood pressure loci identified with a gene-centric array

artículo científico publicado en 2011

Bone marrow mononuclear cells reduce myocardial reperfusion injury by activating the PI3K/Akt survival pathway

artículo científico publicado en 2010

Causal Associations of Adiposity and Body Fat Distribution with Coronary Heart Disease, Stroke Subtypes and Type 2 Diabetes: A Mendelian Randomization Analysis

artículo científico publicado en 2017

Chromosome 2p Shows Significant Linkage to Antihypertensive Response in the British Genetics of Hypertension Study

article

Common Genetic Variants Modulate the Electrocardiographic Tpeak-to-Tend Interval

scientific article published on 29 April 2020

Common Polymorphisms at the CYP17A1 Locus Associate With Steroid Phenotype: Support for Blood Pressure Genome-Wide Association Study Signals at This Locus

artículo científico publicado en 2016

Common Polymorphisms in the CYP11B1 and CYP11B2 Genes: Evidence for a Digenic Influence on Hypertension

article

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies

artículo científico publicado en 2009

Common variants associated with plasma triglycerides and risk for coronary artery disease

artículo científico publicado en 2013

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

artículo científico publicado en 2010

Common variants in the ATP2B1 gene are associated with susceptibility to hypertension: the Japanese Millennium Genome Project

artículo científico publicado en 2010

Common variants near MC4R are associated with fat mass, weight and risk of obesity

artículo científico publicado en 2008

Common variation in the NOS1AP gene is associated with drug-induced QT prolongation and ventricular arrhythmia

artículo científico publicado en 2012

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

artículo científico publicado en 2011

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies

artículo científico publicado en 2008

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

artículo científico publicado en 2009

Correction: Long-term intra-individual reproducibility of heart rate dynamics during exercise and recovery in the UK Biobank cohort

artículo científico publicado en 2018

Correction: The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits.

artículo científico publicado en 2013

Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

artículo científico publicado en 2017

Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study

artículo científico publicado en 2016

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Differentially expressed genes for atrial fibrillation identified by RNA sequencing from paired human left and right atrial appendages

artículo científico publicado en 2019

Directional dominance on stature and cognition in diverse human populations

artículo científico publicado en 2015

Discovery and refinement of loci associated with lipid levels

artículo científico publicado en 2013

Discovery of novel heart rate-associated loci using the Exome Chip

artículo científico publicado en 2017

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

artículo científico publicado en 2020

ECG T‐Wave Morphologic Variations Predict Ventricular Arrhythmic Risk in Low‐ and Moderate‐Risk Populations

artículo científico publicado en 2022

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

article by Matthew B. Lanktree et al published June 2012 in American Journal of Human Genetics

Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals

artículo científico publicado en 2019

Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations

artículo científico publicado en 2014

Electrolytes and electrophysiology: what's next?

artículo científico publicado en 2019

Emerging applications of genome-editing technology to examine functionality of GWAS-associated variants for complex traits.

artículo científico publicado en 2018

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Exome-wide association study of plasma lipids in >300,000 individuals

artículo científico publicado en 2017

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

Exploring hypertension genome-wide association studies findings and impact on pathophysiology, pathways, and pharmacogenetics

artículo científico

Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy

artículo científico publicado en 2011

Gene Variants at Loci Related to Blood Pressure Account for Variation in Response to Antihypertensive Drugs Between Black and White Individuals

artículo científico publicado en 2019

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip

artículo científico publicado en 2009

Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations

artículo científico publicado en 2013

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

artículo científico publicado en 2014

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

scientific article published on 05 May 2020

Genetic Basis and Prognostic Value of Exercise QT Dynamics

scientific article published on 11 June 2020

Genetic Determinants of Electrocardiographic P-wave Duration and Relation to Atrial Fibrillation

artículo científico publicado en 2020

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential hypertension

artículo científico publicado en 2007

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

artículo científico publicado en 2014

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

artículo científico publicado en 2016

Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes

artículo científico publicado en 2014

Genetic evidence of assortative mating in humans

article

Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles

artículo científico publicado en 2016

Genetic loci influencing kidney function and chronic kidney disease

artículo científico publicado en 2010

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variants in PPARGC1B and CNTN4 are associated with thromboxane A2 formation and with cardiovascular event free survival in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT).

artículo científico publicado en 2017

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

artículo científico publicado en 2011

Genetics of essential hypertension

artículo científico publicado en 2004

Genome-Wide Analysis of Left Ventricular Image-Derived Phenotypes Identifies Fourteen Loci Associated With Cardiac Morphogenesis and Heart Failure Development

artículo científico publicado en 2019

Genome-Wide Association Studies Will Unlock the Genetic Basis of Hypertension ⬇️

artículo científico publicado el 1 de diciembre de 2010

Genome-Wide Meta-Analysis of Blood Pressure Response to β1-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies)

artículo científico publicado en 2019

Genome-wide analysis of blood pressure variability and ischemic stroke

artículo científico publicado en 2013

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

artículo científico publicado en 2013

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

artículo científico publicado en 2017

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

artículo científico publicado en 2019

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

artículo científico publicado en 2009

Genome-wide association studies and contribution to cardiovascular physiology

artículo científico publicado en 2015

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia

artículo científico publicado en 2008

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

artículo científico publicado en 2011

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

artículo científico publicado en 2011

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

artículo científico publicado en 2010

Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension

artículo científico publicado en 2010

Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-pro-endothelin-1.

artículo científico publicado en 2013

Genome-wide mapping of human loci for essential hypertension

artículo científico publicado en 2003

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations

artículo científico publicado en 2009

Genomewide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase

artículo científico publicado en 2011

Global sequence properties for superfamily prediction: a machine learning approach

artículo científico publicado en 2009

Glutathione S-transferase variants and hypertension

artículo científico publicado en 2008

Greater risk of severe COVID-19 in Black, Asian and Minority Ethnic populations is not explained by cardiometabolic, socioeconomic or behavioural factors, or by 25(OH)-vitamin D status: study of 1326 cases from the UK Biobank

scientific article published on 19 June 2020

Gut microbiome-based supervised machine learning for clinical diagnosis of inflammatory bowel diseases

artículo científico publicado en 2021

Haplotypes of the ??2-adrenergic receptor gene are associated with essential hypertension in a Singaporean Chinese population

article

Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study

article

Haplotypes of the beta-2 adrenergic receptor associate with high diastolic blood pressure in the Caerphilly prospective study

scientific article published on 01 March 2006

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

Hypertension

Identification of genomic loci associated with resting heart rate and shared genetic predictors with all-cause mortality

artículo científico publicado en 2016

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Increased Support for Linkage of a Novel Locus on Chromosome 5q13 for Essential Hypertension in the British Genetics of Hypertension Study

article

Information capture using SNPs from HapMap and whole-genome chips differs in a sample of inflammatory and cardiovascular gene-centric regions from genome-wide estimates

artículo científico publicado en 2007

Integrated computational and experimental analysis of the neuroendocrine transcriptome in genetic hypertension identifies novel control points for the cardiometabolic syndrome

artículo científico publicado en 2012

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study

artículo científico publicado en 2016

KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern

artículo científico publicado en 2019

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

artículo científico publicado en 2012

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

artículo científico publicado en 2012

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

artículo científico publicado en 2012

Linkage analysis using co-phenotypes in the BRIGHT study reveals novel potential susceptibility loci for hypertension

artículo científico publicado en 2006

Linkage of the Angiotensinogen Gene to Essential Hypertension

article

Loci influencing blood pressure identified using a cardiovascular gene-centric array

artículo científico publicado en 2013

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

artículo científico publicado en 2013

Long-term intra-individual reproducibility of heart rate dynamics during exercise and recovery in the UK Biobank cohort

artículo científico publicado en 2017

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

artículo científico publicado en 2010

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

artículo científico publicado en 2009

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

artículo científico publicado en 2010

Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations

artículo científico publicado en 2013

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

artículo científico publicado en 2016

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

artículo científico publicado en 2019

Modulation of genetic associations with serum urate levels by body-mass-index in humans

artículo científico publicado en 2015

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

scientific article published on 21 May 2020

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

artículo científico publicado en 2019

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

artículo científico publicado en 2019

Multiancestry Study of Gene-Lifestyle Interactions for Cardiovascular Traits in 610 475 Individuals From 124 Cohorts: Design and Rationale

artículo científico publicado en 2017

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

artículo científico publicado en 2017

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

artículo científico publicado en 2017

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

artículo científico publicado en 2018

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Novel polymorphic AluYb8 insertion in the WNK1 gene is associated with blood pressure variation in Europeans

artículo científico publicado en 2011

Over 1000 genetic loci influencing blood pressure with multiple systems and tissues implicated

artículo científico publicado en 2019

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

artículo científico publicado en 2018

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

artículo científico publicado en 2014

Polymorphic variation in the 11beta-hydroxylase gene associates with reduced 11-hydroxylase efficiency

artículo científico publicado en 2006

Polymorphisms in the WNK1 gene are associated with blood pressure variation and urinary potassium excretion

artículo científico publicado en 2009

Poor Bone Quality is Associated With Greater Arterial Stiffness: Insights From the UK Biobank

scientific article published on 22 September 2020

Predicting deleterious nsSNPs: an analysis of sequence and structural attributes

artículo científico publicado en 2006

Prognostic Significance of Left Ventricular Noncompaction: Systematic Review and Meta-Analysis of Observational Studies

scientific article published on 21 January 2020

Protein interaction networks associated with cardiovascular disease and cancer: exploring the effect of bias on shared network properties

artículo científico publicado en 2014

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

artículo científico publicado en 2018

Quantifying the extent to which index event biases influence large genetic association studies

artículo científico publicado en 2016

Quantifying the extent to which index event biases influence large genetic association studies

article

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Reaching the End-Game for GWAS: Machine Learning Approaches for the Prioritization of Complex Disease Loci

artículo científico publicado en 2020

Recent advances in the identification of genes for human hypertension

artículo científico publicado en 2005

SLC2A9 is a high-capacity urate transporter in humans

artículo científico publicado en 2008

Selection of candidate genes in hypertension.

artículo científico publicado en 2005

Sex and smell – an enigma resolved ⬇️

artículo científico publicado el 1 de junio de 1992

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

artículo científico publicado en 2013

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

artículo científico publicado en 2009

State of the Art Review on Genetics and Precision Medicine in Arrhythmogenic Cardiomyopathy

artículo científico publicado en 2020

Targeting 160 candidate genes for blood pressure regulation with a genome-wide genotyping array

artículo científico publicado en 2009

Testing the role of predicted gene knockouts in human anthropometric trait variation

artículo científico publicado en 2016

The biological impact of blood pressure-associated genetic variants in the natriuretic peptide receptor C gene on human vascular smooth muscle.

artículo científico publicado en 2017

The genetic architecture of blood pressure variation

article

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits

artículo científico publicado en 2012

The narrow-sense and common single nucleotide polymorphism heritability of early repolarization

Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system.

artículo científico publicado en 2018

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

scientific article published on 21 December 2018

Two Further Blood Pressure Loci Identified in Ion Channel Genes With a Genecentric Approach

article

Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension

article

Variation in left ventricular cardiac magnetic resonance normal reference ranges: systematic review and meta-analysis

artículo científico publicado en 2020

Vitamin D and high blood pressure: causal association or epiphenomenon?

artículo científico

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda