Lista de obras -

A double-blind placebo-controlled trial of N-acetylcysteine in the treatment of cocaine dependence

artículo científico publicado en 2013

A single intra-PFC infusion of BDNF prevents cocaine-induced alterations in extracellular glutamate within the nucleus accumbens

artículo científico publicado en 2009

AKAP signaling in reinstated cocaine seeking revealed by iTRAQ proteomic analysis

artículo científico publicado en 2011

Accumbens nNOS Interneurons Regulate Cocaine Relapse

artículo científico publicado en 2017

Activation of orbital and medial prefrontal cortex by methylphenidate in cocaine-addicted subjects but not in controls: relevance to addiction.

artículo científico publicado en 2005

An open-label pilot trial of N-acetylcysteine and varenicline in adult cigarette smokers.

artículo científico publicado en 2014

Animal models and brain circuits in drug addiction

artículo científico publicado en 2006

Bipolar disorder and substance misuse: pathological and therapeutic implications of their comorbidity and cross-sensitisation ⬇️

artículo científico publicado el 1 de marzo de 2013

Brain circuitry and the reinstatement of cocaine-seeking behavior

artículo científico publicado en 2003

Ceftriaxone Normalizes Nucleus Accumbens Synaptic Transmission, Glutamate Transport, and Export following Cocaine Self-Administration and Extinction Training ⬇️

artículo científico publicado el 5 de septiembre de 2012

Ceftriaxone restores glutamate homeostasis and prevents relapse to cocaine seeking

artículo científico publicado en 2010

Chemogenetic Activation of an Extinction Neural Circuit Reduces Cue-Induced Reinstatement of Cocaine Seeking

artículo científico publicado en 2016

Chronic N-acetylcysteine during abstinence or extinction after cocaine self-administration produces enduring reductions in drug seeking

artículo científico publicado en 2011

Cocaine activates Homer1 immediate early gene transcription in the mesocorticolimbic circuit: differential regulation by dopamine and glutamate signaling

scientific journal article

Cocaine and amphetamine-like psychostimulants: neurocircuitry and glutamate neuroplasticity

artículo científico publicado en 2007

Cocaine and sucrose rewards recruit different seeking ensembles in the nucleus accumbens core

scientific article published on 28 September 2020

Cocaine-Induced Adaptations in Cellular Redox Balance Contributes to Enduring Behavioral Plasticity ⬇️

artículo científico publicado el 27 de julio de 2011

Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking

artículo científico publicado en 2005

Drug Refraining and Seeking Potentiate Synapses on Distinct Populations of Accumbens Medium Spiny Neurons

artículo científico publicado en 2018

Drug Wanting: Behavioral Sensitization and Relapse to Drug-Seeking Behavior ⬇️

artículo científico publicado el 13 de abril de 2011

Extended access to cocaine self-administration enhances drug-primed reinstatement but not behavioral sensitization

artículo científico publicado en 2007

Extended methamphetamine self-administration in rats results in a selective reduction of dopamine transporter levels in the prefrontal cortex and dorsal striatum not accompanied by marked monoaminergic depletion

artículo científico publicado en 2009

Extinction circuits for fear and addiction overlap in prefrontal cortex

artículo científico publicado en 2009

Extinction training after cocaine self-administration induces glutamatergic plasticity to inhibit cocaine seeking

artículo científico publicado en 2010

Glutamate and reinstatement

artículo científico publicado en 2009

Glutamate release in the nucleus accumbens core is necessary for heroin seeking.

artículo científico publicado en 2008

Glutamate systems in cocaine addiction

artículo científico publicado en 2004

Glutamate transmission in addiction

artículo científico publicado en 2008

Glutamate transporter GLT-1 mediates N-acetylcysteine inhibition of cocaine reinstatement

artículo científico publicado en 2014

Group II Metabotropic Glutamate Receptors Modulate Extracellular Glutamate in the Nucleus Accumbens ⬇️

artículo científico publicado el 1 de enero de 2002

Group II metabotropic glutamate receptors (mGlu2/3) in drug addiction

artículo científico publicado en 2010

Harnessing neuroplasticity for clinical applications ⬇️

artículo científico publicado en 2011

Heroin relapse requires long-term potentiation-like plasticity mediated by NMDA2b-containing receptors.

artículo científico publicado en 2011

Homer proteins regulate sensitivity to cocaine

scientific journal article

Infralimbic prefrontal cortex is responsible for inhibiting cocaine seeking in extinguished rats

artículo científico publicado en 2008

Long-term neuroadaptations produced by withdrawal from repeated cocaine treatment: role of dopaminergic receptors in modulating cortical excitability

artículo científico publicado en 2006

Loss of Plasticity in the D2-Accumbens Pallidal Pathway Promotes Cocaine Seeking.

artículo científico publicado en 2017

Matrix-assisted laser desorption/ionization tissue profiling of secretoneurin in the nucleus accumbens shell from cocaine-sensitized rats

artículo científico publicado en 2010

Modafinil attenuates reinstatement of cocaine seeking: role for cystine-glutamate exchange and metabotropic glutamate receptors ⬇️

artículo científico publicado el 27 de septiembre de 2012

N-Acetylcysteine treatment during acute stress prevents stress-induced augmentation of addictive drug use and relapse

scientific article published on 07 July 2019

NAC1 regulates the recruitment of the proteasome complex into dendritic spines

artículo científico publicado en 2007

Neural circuit competition in cocaine-seeking: roles of the infralimbic cortex and nucleus accumbens shell

artículo científico publicado en 2012

New vistas on cannabis use disorder

artículo científico publicado en 2017

Non-Opioid Treatments for Opioid Use Disorder: Rationales and Data to Date

artículo científico publicado en 2020

Nrf2 gene deletion fails to alter psychostimulant-induced behavior or neurotoxicity.

artículo científico publicado en 2006

Optogenetic inhibition of cocaine seeking in rats

artículo científico publicado en 2012

Optogenetic inhibition of cortical afferents in the nucleus accumbens simultaneously prevents cue-induced transient synaptic potentiation and cocaine-seeking behavior

artículo científico publicado en 2015

Potential role of N-acetylcysteine in the management of substance use disorders

artículo científico publicado en 2014

Rapid, transient synaptic plasticity in addiction ⬇️

artículo científico publicado el 29 de abril de 2013

Reduced LTP and LTD in prefrontal cortex synapses in the nucleus accumbens after heroin self-administration

artículo científico publicado en 2012

Relapse-associated Transient Synaptic Potentiation Requires Integrin-mediated Activation of Focal Adhesion Kinase and Cofilin in D1-expressing Neurons

scientific article published on 13 October 2020

Requirement for the POZ/BTB protein NAC1 in acute but not chronic psychomotor stimulant response

artículo científico publicado en 2008

Restoration of Kv7 Channel-Mediated Inhibition Reduces Cued-Reinstatement of Cocaine Seeking.

artículo científico publicado en 2018

Reversing cocaine-induced synaptic potentiation provides enduring protection from relapse.

artículo científico publicado en 2010

Role of mGluR5 neurotransmission in reinstated cocaine-seeking

artículo científico publicado en 2012

Role of the prefrontal cortex and nucleus accumbens in reinstating methamphetamine seeking

artículo científico publicado en 2010

Safety and tolerability of N-acetylcysteine in cocaine-dependent individuals.

artículo científico publicado en 2006

Stress‐induced sensitization to cocaine: actin cytoskeleton remodeling within mesocorticolimbic nuclei ⬇️

artículo científico publicado el 12 de agosto de 2012

Supplementing high-density SNP microarrays for additional coverage of disease-related genes: addiction as a paradigm

artículo científico publicado en 2009

Synaptic plasticity mediating cocaine relapse requires matrix metalloproteinases.

artículo científico publicado en 2014

The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities. ⬇️

artículo científico publicado en 2012

The effect of N-acetylcysteine in the nucleus accumbens on neurotransmission and relapse to cocaine

artículo científico publicado en 2012

The infralimbic cortex regulates the consolidation of extinction after cocaine self-administration

artículo científico publicado en 2010

The loss of NMDAR-dependent LTD following cannabinoid self-administration is restored by positive allosteric modulation of CB1 receptors

scientific article published on 16 November 2019

The origin and neuronal function of in vivo nonsynaptic glutamate.

artículo científico publicado en 2002

The role of cystine-glutamate exchange in nicotine dependence in rats and humans

scientific journal article

The temporal sequence of changes in gene expression by drugs of abuse

artículo científico publicado en 2003

Transient synaptic potentiation in nucleus accumbens shell during refraining from cocaine seeking

scientific article published on 06 May 2019

Using glutamate homeostasis as a target for treating addictive disorders

artículo científico publicado en 2010

Ventral Pallidum Is the Primary Target for Accumbens D1 Projections Driving Cocaine Seeking

artículo científico publicado en 2019

α2δ-1 signaling in nucleus accumbens is necessary for cocaine-induced relapse.

artículo científico publicado en 2014

Lista de obras de

A double-blind placebo-controlled trial of N-acetylcysteine in the treatment of cocaine dependence

A single intra-PFC infusion of BDNF prevents cocaine-induced alterations in extracellular glutamate within the nucleus accumbens

AKAP signaling in reinstated cocaine seeking revealed by iTRAQ proteomic analysis

Accumbens nNOS Interneurons Regulate Cocaine Relapse

Activation of orbital and medial prefrontal cortex by methylphenidate in cocaine-addicted subjects but not in controls: relevance to addiction.

An open-label pilot trial of N-acetylcysteine and varenicline in adult cigarette smokers.

Animal models and brain circuits in drug addiction

Bipolar disorder and substance misuse: pathological and therapeutic implications of their comorbidity and cross-sensitisation ⬇️

Brain circuitry and the reinstatement of cocaine-seeking behavior

Ceftriaxone Normalizes Nucleus Accumbens Synaptic Transmission, Glutamate Transport, and Export following Cocaine Self-Administration and Extinction Training ⬇️

Ceftriaxone restores glutamate homeostasis and prevents relapse to cocaine seeking

Chemogenetic Activation of an Extinction Neural Circuit Reduces Cue-Induced Reinstatement of Cocaine Seeking

Chronic N-acetylcysteine during abstinence or extinction after cocaine self-administration produces enduring reductions in drug seeking

Cocaine activates Homer1 immediate early gene transcription in the mesocorticolimbic circuit: differential regulation by dopamine and glutamate signaling

Cocaine and amphetamine-like psychostimulants: neurocircuitry and glutamate neuroplasticity

Cocaine and sucrose rewards recruit different seeking ensembles in the nucleus accumbens core

Cocaine-Induced Adaptations in Cellular Redox Balance Contributes to Enduring Behavioral Plasticity ⬇️

Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking

Drug Refraining and Seeking Potentiate Synapses on Distinct Populations of Accumbens Medium Spiny Neurons

Drug Wanting: Behavioral Sensitization and Relapse to Drug-Seeking Behavior ⬇️

Extended access to cocaine self-administration enhances drug-primed reinstatement but not behavioral sensitization

Extended methamphetamine self-administration in rats results in a selective reduction of dopamine transporter levels in the prefrontal cortex and dorsal striatum not accompanied by marked monoaminergic depletion

Extinction circuits for fear and addiction overlap in prefrontal cortex

Extinction training after cocaine self-administration induces glutamatergic plasticity to inhibit cocaine seeking

Glutamate and reinstatement

Glutamate release in the nucleus accumbens core is necessary for heroin seeking.

Glutamate systems in cocaine addiction

Glutamate transmission in addiction

Glutamate transporter GLT-1 mediates N-acetylcysteine inhibition of cocaine reinstatement

Group II Metabotropic Glutamate Receptors Modulate Extracellular Glutamate in the Nucleus Accumbens ⬇️

Group II metabotropic glutamate receptors (mGlu2/3) in drug addiction

Harnessing neuroplasticity for clinical applications ⬇️

Heroin relapse requires long-term potentiation-like plasticity mediated by NMDA2b-containing receptors.

Homer proteins regulate sensitivity to cocaine

Infralimbic prefrontal cortex is responsible for inhibiting cocaine seeking in extinguished rats

Long-term neuroadaptations produced by withdrawal from repeated cocaine treatment: role of dopaminergic receptors in modulating cortical excitability

Loss of Plasticity in the D2-Accumbens Pallidal Pathway Promotes Cocaine Seeking.

Matrix-assisted laser desorption/ionization tissue profiling of secretoneurin in the nucleus accumbens shell from cocaine-sensitized rats

Modafinil attenuates reinstatement of cocaine seeking: role for cystine-glutamate exchange and metabotropic glutamate receptors ⬇️

N-Acetylcysteine treatment during acute stress prevents stress-induced augmentation of addictive drug use and relapse

NAC1 regulates the recruitment of the proteasome complex into dendritic spines

Neural circuit competition in cocaine-seeking: roles of the infralimbic cortex and nucleus accumbens shell

New vistas on cannabis use disorder

Non-Opioid Treatments for Opioid Use Disorder: Rationales and Data to Date

Nrf2 gene deletion fails to alter psychostimulant-induced behavior or neurotoxicity.

Optogenetic inhibition of cocaine seeking in rats

Optogenetic inhibition of cortical afferents in the nucleus accumbens simultaneously prevents cue-induced transient synaptic potentiation and cocaine-seeking behavior

Potential role of N-acetylcysteine in the management of substance use disorders

Rapid, transient synaptic plasticity in addiction ⬇️

Reduced LTP and LTD in prefrontal cortex synapses in the nucleus accumbens after heroin self-administration

Relapse-associated Transient Synaptic Potentiation Requires Integrin-mediated Activation of Focal Adhesion Kinase and Cofilin in D1-expressing Neurons

Requirement for the POZ/BTB protein NAC1 in acute but not chronic psychomotor stimulant response

Restoration of Kv7 Channel-Mediated Inhibition Reduces Cued-Reinstatement of Cocaine Seeking.

Reversing cocaine-induced synaptic potentiation provides enduring protection from relapse.

Role of mGluR5 neurotransmission in reinstated cocaine-seeking

Role of the prefrontal cortex and nucleus accumbens in reinstating methamphetamine seeking

Safety and tolerability of N-acetylcysteine in cocaine-dependent individuals.

Stress‐induced sensitization to cocaine: actin cytoskeleton remodeling within mesocorticolimbic nuclei ⬇️

Supplementing high-density SNP microarrays for additional coverage of disease-related genes: addiction as a paradigm

Synaptic plasticity mediating cocaine relapse requires matrix metalloproteinases.

The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities. ⬇️

The effect of N-acetylcysteine in the nucleus accumbens on neurotransmission and relapse to cocaine

The infralimbic cortex regulates the consolidation of extinction after cocaine self-administration

The loss of NMDAR-dependent LTD following cannabinoid self-administration is restored by positive allosteric modulation of CB1 receptors

The origin and neuronal function of in vivo nonsynaptic glutamate.

The role of cystine-glutamate exchange in nicotine dependence in rats and humans

The temporal sequence of changes in gene expression by drugs of abuse

Transient synaptic potentiation in nucleus accumbens shell during refraining from cocaine seeking

Using glutamate homeostasis as a target for treating addictive disorders

Ventral Pallidum Is the Primary Target for Accumbens D1 Projections Driving Cocaine Seeking

α2δ-1 signaling in nucleus accumbens is necessary for cocaine-induced relapse.