Lista de obras -

A dual role for Integrin α6β4 in modulating Hereditary Neuropathy with liability to Pressure Palsies

artículo científico publicado en 2018

A laminin-2, dystroglycan, utrophin axis is required for compartmentalization and elongation of myelin segments

artículo científico publicado en 2009

A nonsense mutation in Myelin Protein Zero causes congenital hypomyelination neuropathy through altered P0 membrane targeting and gain of abnormal function

artículo científico publicado en 2019

A photoprotein in mouse embryonic stem cells measures Ca2+ mobilization in cells and in animals

artículo científico publicado en 2010

Ablation of Perk in Schwann Cells Improves Myelination in the S63del Charcot-Marie-Tooth 1B Mouse.

artículo científico publicado en 2016

Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice

artículo científico publicado en 2008

Acetyl-CoA production from pyruvate is not necessary for preservation of myelin.

artículo científico publicado en 2017

Actin polymerization is essential for myelin sheath fragmentation during Wallerian degeneration.

artículo científico publicado en 2011

Active gene repression by the Egr2.NAB complex during peripheral nerve myelination

scientific journal article

Alpha6 beta4 and alpha6 beta1 integrins in astrocytomas and other CNS tumors

artículo científico publicado en 1996

Alpha6beta4 integrin and dystroglycan cooperate to stabilize the myelin sheath

artículo científico publicado en 2008

Altered Trafficking and Processing of GALC Mutants Correlates with Globoid Cell Leukodystrophy Severity

artículo científico publicado en 2016

Basal lamina: Schwann cells wrap to the rhythm of space-time.

artículo científico publicado en 2006

Beta1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination

artículo científico publicado en 2007

Both laminin and Schwann cell dystroglycan are necessary for proper clustering of sodium channels at nodes of Ranvier.

artículo científico publicado en 2005

Brainstem development requires galactosylceramidase and is critical for pathogenesis in a model of Krabbe disease

artículo científico publicado en 2020

Characterization of a Schwann cell enhancer in the myelin basic protein gene

scientific article published on 01 November 2004

Conditional disruption of beta 1 integrin in Schwann cells impedes interactions with axons

artículo científico publicado en 2002

Corrigendum: Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy

artículo científico publicado en 2019

Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice.

artículo científico publicado en 2012

DDIT4/REDD1/RTP801 is a novel negative regulator of Schwann cell myelination

artículo científico publicado en 2013

Deletion of Calcineurin in Schwann Cells Does Not Affect Developmental Myelination, But Reduces Autophagy and Delays Myelin Clearance after Peripheral Nerve Injury

artículo científico publicado en 2020

Different Intracellular Pathomechanisms Produce Diverse Myelin Protein Zero Neuropathies in Transgenic Mice

artículo científico publicado en 2006

Direct regulation of myelin protein zero expression by the Egr2 transactivator

artículo científico publicado en 2005

Disruption of Mtmr2 produces CMT4B1-like neuropathy with myelin outfolding and impaired spermatogenesis

artículo científico publicado en 2004

Dysmyelinated lower motor neurons retract and regenerate dysfunctional synaptic terminals.

artículo científico publicado en 2004

Enhanced axonal neuregulin-1 type-III signaling ameliorates neurophysiology and hypomyelination in a Charcot-Marie-Tooth type 1B mouse model

scientific article published on 01 March 2019

Expression of laminin receptors in schwann cell differentiation: evidence for distinct roles.

artículo científico publicado en 2003

Foot pad skin biopsy in mouse models of hereditary neuropathy

artículo científico publicado en 2010

Generation of a LacZ reporter transgenic mouse line for the stereological analysis of oligodendrocyte loss in galactosylceramidase deficiency

artículo científico publicado en 2016

Genetic interaction between MTMR2 and FIG4 phospholipid phosphatases involved in Charcot-Marie-Tooth neuropathies

artículo científico publicado en 2011

Identification and characterization of ZFP-57, a novel zinc finger transcription factor in the mammalian peripheral nervous system

scientific journal article

Impairment of protein degradation and proteasome function in hereditary neuropathies.

artículo científico publicado en 2017

In vivo detection of Egr2 binding to target genes during peripheral nerve myelination

artículo científico publicado en 2006

Jab1 regulates Schwann cell proliferation and axonal sorting through p27

Jab1 regulates Schwann cell proliferation and axonal sorting through p27.

artículo científico publicado en 2013

Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination

artículo científico publicado en 2017

Laminins and their receptors in Schwann cells and hereditary neuropathies

artículo científico publicado en 2005

Loss of Fig4 in both Schwann cells and motor neurons contributes to CMT4J neuropathy

artículo científico publicado en 2014

Loss of Mtmr2 phosphatase in Schwann cells but not in motor neurons causes Charcot-Marie-Tooth type 4B1 neuropathy with myelin outfoldings.

artículo científico publicado en 2005

Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells

artículo científico publicado en 2013

MMP2-9 cleavage of dystroglycan alters the size and molecular composition of Schwann cell domains ⬇️

artículo científico publicado el 24 de agosto de 2011

Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction

artículo científico publicado en 2020

Metabolic profiling reveals biochemical pathways and potential biomarkers associated with the pathogenesis of Krabbe disease

artículo científico publicado en 2016

MicroRNA-deficient Schwann cells display congenital hypomyelination

artículo científico publicado en 2010

Microprocessor complex subunit DiGeorge syndrome critical region gene 8 (Dgcr8) is required for schwann cell myelination and myelin maintenance

artículo científico publicado en 2015

Molecular characterization and expression analysis of Mtmr2, mouse homologue of MTMR2, the Myotubularin-related 2 gene, mutated in CMT4B.

artículo científico publicado en 2002

Molecular mechanisms of inherited demyelinating neuropathies

artículo científico publicado en 2008

MpzR98C arrests Schwann cell development in a mouse model of early-onset Charcot–Marie–Tooth disease type 1B ⬇️

artículo científico publicado el 10 de junio de 2012

Myelin under stress

artículo científico publicado en 2009

Myotubularin-related 2 protein phosphatase and neurofilament light chain protein, both mutated in CMT neuropathies, interact in peripheral nerve

artículo científico publicado en 2003

N-WASp is required for Schwann cell cytoskeletal dynamics, normal myelin gene expression and peripheral nerve myelination.

artículo científico publicado en 2011

Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy

scientific article published on 01 April 2019

Non-redundant function of dystroglycan and β1 integrins in radial sorting of axons

artículo científico

Oligodendroglial progenitor cell therapy limits central neurological deficits in mice with metachromatic leukodystrophy.

artículo científico publicado en 2006

P0 (protein zero) mutation S34C underlies instability of internodal myelin in S63C mice.

artículo científico publicado en 2010

P0S63del impedes the arrival of wild-type P0 glycoprotein to myelin in CMT1B mice

artículo científico publicado el 1 de junio de 2011

Peripheral Nerve Dysmyelination Due to P0 Glycoprotein Overexpression Is Dose-Dependent

artículo científico publicado en 1999

Perk Ablation Ameliorates Myelination in S63del-Charcot-Marie-Tooth 1B Neuropathy

artículo científico publicado en 2016

Perlecan is recruited by dystroglycan to nodes of Ranvier and binds the clustering molecule gliomedin.

artículo científico publicado en 2015

Phosphorylation of eIF2α promotes Schwann cell differentiation and myelination in CMT1B mice with activated UPR

scientific article published on 24 September 2020

Proteolipid protein cannot replace P0 protein as the major structural protein of peripheral nervous system myelin.

artículo científico publicado en 2014

Regulation of cholesterol/lipid biosynthetic genes by Egr2/Krox20 during peripheral nerve myelination

artículo científico publicado en 2005

Resetting translational homeostasis restores myelination in Charcot-Marie-Tooth disease type 1B mice

artículo científico publicado en 2013

Role of integrins in peripheral nerves and hereditary neuropathies

artículo científico publicado en 2006

SCAP is required for timely and proper myelin membrane synthesis

artículo científico publicado en 2009

Schwann cell LRP1 regulates remak bundle ultrastructure and axonal interactions to prevent neuropathic pain

scientific article published on March 2013

Schwann cell-specific ablation of laminin gamma1 causes apoptosis and prevents proliferation

artículo científico publicado en 2005

Schwann cells ER-associated degradation contributes to myelin maintenance in adult nerves and limits demyelination in CMT1B mice

artículo científico publicado en 2019

Selective knockdown of mutant SOD1 in Schwann cells ameliorates disease in G85R mutant SOD1 transgenic mice ⬇️

artículo científico publicado el 2 de junio de 2012

Signals to promote myelin formation and repair

artículo científico publicado en 2010

Structure and stability of internodal myelin in mouse models of hereditary neuropathy.

artículo científico publicado en 2005

Sustained Expression of Negative Regulators of Myelination Protects Schwann Cells from Dysmyelination in a Charcot-Marie-Tooth 1B Mouse Model.

artículo científico publicado en 2018

TACE (ADAM17) inhibits Schwann cell myelination

artículo científico publicado en 2011

TGFbeta type II receptor signaling controls Schwann cell death and proliferation in developing nerves.

artículo científico publicado en 2006

The Gdap1 knockout mouse mechanistically links redox control to Charcot-Marie-Tooth disease.

artículo científico publicado en 2014

Unique role of dystroglycan in peripheral nerve myelination, nodal structure, and sodium channel stabilization

scientific journal article

YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells

artículo científico publicado en 2016

α6β1 and α7β1 integrins are required in Schwann cells to sort axons.

artículo científico publicado en 2013

αV integrins in Schwann cells promote attachment to axons, but are dispensable in vivo

artículo científico publicado en 2020

Lista de obras de

A dual role for Integrin α6β4 in modulating Hereditary Neuropathy with liability to Pressure Palsies

A laminin-2, dystroglycan, utrophin axis is required for compartmentalization and elongation of myelin segments

A nonsense mutation in Myelin Protein Zero causes congenital hypomyelination neuropathy through altered P0 membrane targeting and gain of abnormal function

A photoprotein in mouse embryonic stem cells measures Ca2+ mobilization in cells and in animals

Ablation of Perk in Schwann Cells Improves Myelination in the S63del Charcot-Marie-Tooth 1B Mouse.

Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice

Acetyl-CoA production from pyruvate is not necessary for preservation of myelin.

Actin polymerization is essential for myelin sheath fragmentation during Wallerian degeneration.

Active gene repression by the Egr2.NAB complex during peripheral nerve myelination

Alpha6 beta4 and alpha6 beta1 integrins in astrocytomas and other CNS tumors

Alpha6beta4 integrin and dystroglycan cooperate to stabilize the myelin sheath

Altered Trafficking and Processing of GALC Mutants Correlates with Globoid Cell Leukodystrophy Severity

Basal lamina: Schwann cells wrap to the rhythm of space-time.

Beta1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination

Both laminin and Schwann cell dystroglycan are necessary for proper clustering of sodium channels at nodes of Ranvier.

Brainstem development requires galactosylceramidase and is critical for pathogenesis in a model of Krabbe disease

Characterization of a Schwann cell enhancer in the myelin basic protein gene

Conditional disruption of beta 1 integrin in Schwann cells impedes interactions with axons

Corrigendum: Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy

Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice.

DDIT4/REDD1/RTP801 is a novel negative regulator of Schwann cell myelination

Deletion of Calcineurin in Schwann Cells Does Not Affect Developmental Myelination, But Reduces Autophagy and Delays Myelin Clearance after Peripheral Nerve Injury

Different Intracellular Pathomechanisms Produce Diverse Myelin Protein Zero Neuropathies in Transgenic Mice

Direct regulation of myelin protein zero expression by the Egr2 transactivator

Disruption of Mtmr2 produces CMT4B1-like neuropathy with myelin outfolding and impaired spermatogenesis

Dysmyelinated lower motor neurons retract and regenerate dysfunctional synaptic terminals.

Enhanced axonal neuregulin-1 type-III signaling ameliorates neurophysiology and hypomyelination in a Charcot-Marie-Tooth type 1B mouse model

Expression of laminin receptors in schwann cell differentiation: evidence for distinct roles.

Foot pad skin biopsy in mouse models of hereditary neuropathy

Generation of a LacZ reporter transgenic mouse line for the stereological analysis of oligodendrocyte loss in galactosylceramidase deficiency

Genetic interaction between MTMR2 and FIG4 phospholipid phosphatases involved in Charcot-Marie-Tooth neuropathies

Identification and characterization of ZFP-57, a novel zinc finger transcription factor in the mammalian peripheral nervous system

Impairment of protein degradation and proteasome function in hereditary neuropathies.

In vivo detection of Egr2 binding to target genes during peripheral nerve myelination

Jab1 regulates Schwann cell proliferation and axonal sorting through p27

Jab1 regulates Schwann cell proliferation and axonal sorting through p27.

Laminin 211 inhibits protein kinase A in Schwann cells to modulate neuregulin 1 type III-driven myelination

Laminins and their receptors in Schwann cells and hereditary neuropathies

Loss of Fig4 in both Schwann cells and motor neurons contributes to CMT4J neuropathy

Loss of Mtmr2 phosphatase in Schwann cells but not in motor neurons causes Charcot-Marie-Tooth type 4B1 neuropathy with myelin outfoldings.

Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells

MMP2-9 cleavage of dystroglycan alters the size and molecular composition of Schwann cell domains ⬇️

Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction

Metabolic profiling reveals biochemical pathways and potential biomarkers associated with the pathogenesis of Krabbe disease

MicroRNA-deficient Schwann cells display congenital hypomyelination

Microprocessor complex subunit DiGeorge syndrome critical region gene 8 (Dgcr8) is required for schwann cell myelination and myelin maintenance

Molecular characterization and expression analysis of Mtmr2, mouse homologue of MTMR2, the Myotubularin-related 2 gene, mutated in CMT4B.

Molecular mechanisms of inherited demyelinating neuropathies

MpzR98C arrests Schwann cell development in a mouse model of early-onset Charcot–Marie–Tooth disease type 1B ⬇️

Myelin under stress

Myotubularin-related 2 protein phosphatase and neurofilament light chain protein, both mutated in CMT neuropathies, interact in peripheral nerve

N-WASp is required for Schwann cell cytoskeletal dynamics, normal myelin gene expression and peripheral nerve myelination.

Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy

Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy

Non-redundant function of dystroglycan and β1 integrins in radial sorting of axons

Oligodendroglial progenitor cell therapy limits central neurological deficits in mice with metachromatic leukodystrophy.

P0 (protein zero) mutation S34C underlies instability of internodal myelin in S63C mice.

P0S63del impedes the arrival of wild-type P0 glycoprotein to myelin in CMT1B mice

Peripheral Nerve Dysmyelination Due to P0 Glycoprotein Overexpression Is Dose-Dependent

Perk Ablation Ameliorates Myelination in S63del-Charcot-Marie-Tooth 1B Neuropathy

Perlecan is recruited by dystroglycan to nodes of Ranvier and binds the clustering molecule gliomedin.

Phosphorylation of eIF2α promotes Schwann cell differentiation and myelination in CMT1B mice with activated UPR

Proteolipid protein cannot replace P0 protein as the major structural protein of peripheral nervous system myelin.

Regulation of cholesterol/lipid biosynthetic genes by Egr2/Krox20 during peripheral nerve myelination

Resetting translational homeostasis restores myelination in Charcot-Marie-Tooth disease type 1B mice

Role of integrins in peripheral nerves and hereditary neuropathies

SCAP is required for timely and proper myelin membrane synthesis

Schwann cell LRP1 regulates remak bundle ultrastructure and axonal interactions to prevent neuropathic pain

Schwann cell-specific ablation of laminin gamma1 causes apoptosis and prevents proliferation

Schwann cells ER-associated degradation contributes to myelin maintenance in adult nerves and limits demyelination in CMT1B mice

Selective knockdown of mutant SOD1 in Schwann cells ameliorates disease in G85R mutant SOD1 transgenic mice ⬇️

Signals to promote myelin formation and repair

Structure and stability of internodal myelin in mouse models of hereditary neuropathy.

Sustained Expression of Negative Regulators of Myelination Protects Schwann Cells from Dysmyelination in a Charcot-Marie-Tooth 1B Mouse Model.

TACE (ADAM17) inhibits Schwann cell myelination

TGFbeta type II receptor signaling controls Schwann cell death and proliferation in developing nerves.

The Gdap1 knockout mouse mechanistically links redox control to Charcot-Marie-Tooth disease.

Unique role of dystroglycan in peripheral nerve myelination, nodal structure, and sodium channel stabilization

YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells