Lista de obras -

A major transactivator of varicella-zoster virus, the immediate-early protein IE62, contains a potent N-terminal activation domain.

artículo científico publicado en 1993

A multi-valent vaccinia virus-based tuberculosis vaccine molecularly adjuvanted with interleukin-15 induces robust immune responses in mice

artículo científico publicado en 2009

A practical in vitro growth inhibition assay for the evaluation of TB vaccines

artículo científico publicado en 2009

Antibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytes

artículo científico publicado en 2009

Characterization of a Human Stromal Cell Line Supporting Hematopoietic Progenitor Cell Proliferation: Effect of HIV Expression

artículo científico publicado en 1995

Chimeric antigen receptor modified T cells that target chemokine receptor CCR4 as a therapeutic modality for T-cell malignancies.

artículo científico publicado en 2017

Co-expression of Interleukin-15 Enhances the Protective Immune Responses Induced by Immunization with a Murine Malaria MVA-Based Vaccine Encoding the Circumsporozoite Protein

artículo científico publicado en 2015

Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity

artículo científico publicado en 2003

Deregulation of miRNAs-cMYC circuits is a key event in refractory celiac disease type-2 lymphomagenesis

scientific article published on 18 May 2020

Development of a highly efficacious vaccinia-based dual vaccine against smallpox and anthrax, two important bioterror entities ⬇️

artículo científico publicado el 4 de octubre de 2010

Development of a murine mycobacterial growth inhibition assay for evaluating vaccines against Mycobacterium tuberculosis

artículo científico publicado en 2009

Development of smallpox vaccine candidates with integrated interleukin-15 that demonstrate superior immunogenicity, efficacy, and safety in mice

artículo científico publicado en 2007

Herpes simplex virus trans-regulatory protein ICP27 stabilizes and binds to 3' ends of labile mRNA.

artículo científico publicado en 1995

Highly persistent and effective prime/boost regimens against tuberculosis that use a multivalent modified vaccine virus Ankara-based tuberculosis vaccine with interleukin-15 as a molecular adjuvant

artículo científico publicado en 2010

IL-15 adjuvanted multivalent vaccinia-based universal influenza vaccine requires CD4+ T cells for heterosubtypic protection

artículo científico publicado en 2014

IL-15 as a mediator of CD4+ help for CD8+ T cell longevity and avoidance of TRAIL-mediated apoptosis

artículo científico publicado en 2008

IL-15/IL-15Ralpha-mediated avidity maturation of memory CD8+ T cells.

scholarly article

IL15 by Continuous Intravenous Infusion to Adult Patients with Solid Tumors in a Phase I Trial Induced Dramatic NK-Cell Subset Expansion

artículo científico publicado en 2019

Inclusion of an E7 DNA Amplification Test Improves the Robustness of Human Papillomavirus-Associated Oropharyngeal Squamous Cell Carcinoma Diagnosis

artículo científico publicado en 2020

Janus Kinase Inhibitor Tofacitinib Shows Potent Efficacy in a Mouse Model of Autoimmune Lymphoproliferative Syndrome (ALPS).

artículo científico publicado en 2015

Malaria infections do not compromise vaccine-induced immunity against tuberculosis in mice

artículo científico publicado en 2011

Overcoming CD4 deficiency to induce long-lived memory CD8+ CTL.

artículo científico publicado en 2006

Protection by universal influenza vaccine is mediated by memory CD4 T cells

scientific article published on 07 June 2018

Protective-antigen (PA) based anthrax vaccines confer protection against inhalation anthrax by precluding the establishment of a systemic infection

artículo científico publicado en 2013

Providing a Microenvironment for the Development of Human CD34+ Hematopoietic Cells in SCID Mice

artículo científico publicado en 1997

Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer

artículo científico publicado en 2014

Regulation of varicella-zoster virus gene expression in human T lymphocytes ⬇️

artículo científico publicado el 1 de septiembre de 1992

Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques

artículo científico publicado en 2011

Smallpox vaccine with integrated IL-15 demonstrates enhanced in vivo viral clearance in immunodeficient mice and confers long term protection against a lethal monkeypox challenge in cynomolgus monkeys

artículo científico publicado en 2010

The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use

artículo científico publicado en 2012

The safety of post-exposure vaccination of mice infected with Mycobacterium tuberculosis

artículo científico publicado en 2008

The varicella-zoster virus immediate early protein, IE62, can positively regulate its cognate promoter

artículo científico publicado el 1 de noviembre de 1992

Tofacitinib, a janus kinase inhibitor demonstrates efficacy in an IL-15 transgenic mouse model that recapitulates pathologic manifestations of celiac disease

artículo científico publicado en 2012

Transgenic mice that overexpress human IL-15 in enterocytes recapitulate both B and T cell-mediated pathologic manifestations of celiac disease

artículo científico publicado en 2011

Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates

artículo científico publicado en 2010

Vaccine-induced T cell protection from influenza viruses

scientific article published on 01 October 2019

Vaccinia virus-based multivalent H5N1 avian influenza vaccines adjuvanted with IL-15 confer sterile cross-clade protection in mice

artículo científico publicado en 2009

Varicella-zoster virus open reading frame 4 encodes a transcriptional activator that is functionally distinct from that of herpes simplex virus homology ICP27.

artículo científico publicado en 1994

Lista de obras de

A major transactivator of varicella-zoster virus, the immediate-early protein IE62, contains a potent N-terminal activation domain.

A multi-valent vaccinia virus-based tuberculosis vaccine molecularly adjuvanted with interleukin-15 induces robust immune responses in mice

A practical in vitro growth inhibition assay for the evaluation of TB vaccines

Antibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytes

Characterization of a Human Stromal Cell Line Supporting Hematopoietic Progenitor Cell Proliferation: Effect of HIV Expression

Chimeric antigen receptor modified T cells that target chemokine receptor CCR4 as a therapeutic modality for T-cell malignancies.

Co-expression of Interleukin-15 Enhances the Protective Immune Responses Induced by Immunization with a Murine Malaria MVA-Based Vaccine Encoding the Circumsporozoite Protein

Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity

Deregulation of miRNAs-cMYC circuits is a key event in refractory celiac disease type-2 lymphomagenesis

Development of a highly efficacious vaccinia-based dual vaccine against smallpox and anthrax, two important bioterror entities ⬇️

Development of a murine mycobacterial growth inhibition assay for evaluating vaccines against Mycobacterium tuberculosis

Development of smallpox vaccine candidates with integrated interleukin-15 that demonstrate superior immunogenicity, efficacy, and safety in mice

Herpes simplex virus trans-regulatory protein ICP27 stabilizes and binds to 3' ends of labile mRNA.

Highly persistent and effective prime/boost regimens against tuberculosis that use a multivalent modified vaccine virus Ankara-based tuberculosis vaccine with interleukin-15 as a molecular adjuvant

IL-15 adjuvanted multivalent vaccinia-based universal influenza vaccine requires CD4+ T cells for heterosubtypic protection

IL-15 as a mediator of CD4+ help for CD8+ T cell longevity and avoidance of TRAIL-mediated apoptosis

IL-15/IL-15Ralpha-mediated avidity maturation of memory CD8+ T cells.

IL15 by Continuous Intravenous Infusion to Adult Patients with Solid Tumors in a Phase I Trial Induced Dramatic NK-Cell Subset Expansion

Inclusion of an E7 DNA Amplification Test Improves the Robustness of Human Papillomavirus-Associated Oropharyngeal Squamous Cell Carcinoma Diagnosis

Janus Kinase Inhibitor Tofacitinib Shows Potent Efficacy in a Mouse Model of Autoimmune Lymphoproliferative Syndrome (ALPS).

Malaria infections do not compromise vaccine-induced immunity against tuberculosis in mice

Overcoming CD4 deficiency to induce long-lived memory CD8+ CTL.

Protection by universal influenza vaccine is mediated by memory CD4 T cells

Protective-antigen (PA) based anthrax vaccines confer protection against inhalation anthrax by precluding the establishment of a systemic infection

Providing a Microenvironment for the Development of Human CD34+ Hematopoietic Cells in SCID Mice

Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer

Regulation of varicella-zoster virus gene expression in human T lymphocytes ⬇️

Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques

Smallpox vaccine with integrated IL-15 demonstrates enhanced in vivo viral clearance in immunodeficient mice and confers long term protection against a lethal monkeypox challenge in cynomolgus monkeys

The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use

The safety of post-exposure vaccination of mice infected with Mycobacterium tuberculosis

The varicella-zoster virus immediate early protein, IE62, can positively regulate its cognate promoter

Tofacitinib, a janus kinase inhibitor demonstrates efficacy in an IL-15 transgenic mouse model that recapitulates pathologic manifestations of celiac disease

Transgenic mice that overexpress human IL-15 in enterocytes recapitulate both B and T cell-mediated pathologic manifestations of celiac disease

Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates

Vaccine-induced T cell protection from influenza viruses

Vaccinia virus-based multivalent H5N1 avian influenza vaccines adjuvanted with IL-15 confer sterile cross-clade protection in mice

Varicella-zoster virus open reading frame 4 encodes a transcriptional activator that is functionally distinct from that of herpes simplex virus homology ICP27.