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A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14-3-3

A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14-3-3.

artículo científico publicado en 2017

A Natural-Product Switch for a Dynamic Protein Interface

A Structural Study of the Cytoplasmic Chaperone Effect of 14-3-3 Proteins on Ataxin-1

artículo científico publicado en 2021

A multi-gram-scale stereoselective synthesis of Z -endoxifen

scholarly article by Lech-Gustav Milroy published in May 2018

A natural-product switch for a dynamic protein interface

artículo científico publicado en 2014

A sample preparation method for recovering suppressed analyte ions in MALDI TOF MS.

artículo científico publicado en 2015

A study on the effect of synthetic α-to-β3-amino acid mutations on the binding of phosphopeptides to 14-3-3 proteins

scientific article published on 01 December 2019

Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid-binding Globulins

artículo científico publicado en 2011

Batch and Flow Synthesis of Disulfides by Visible-Light-Induced TiO2 Photocatalysis

artículo científico publicado en 2016

Biophysical Characterization of Nucleophosmin Interactions with Human Immunodeficiency Virus Rev and Herpes Simplex Virus US11.

artículo científico publicado en 2015

Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR.

artículo científico publicado en 2016

Characterization of Coding/Noncoding Variants for SHROOM3 in Patients with CKD.

artículo científico publicado en 2018

Chemical variation of natural product-like scaffolds: design and synthesis of spiroketal derivatives

article by Giovanna Zinzalla et al published 2006 in Organic and Biomolecular Chemistry

Chemical variation of natural-product-like scaffolds: design, synthesis, and biological activity of fused bicyclic acetal derivatives

artículo científico publicado en 2007

Communication: Probing the absolute configuration of chiral molecules at aqueous interfaces

artículo científico publicado en 2015

Cooperativity basis for small-molecule stabilization of protein-protein interactions

scientific article published on 25 January 2019

Designed Spiroketal Protein Modulation

artículo científico publicado en 2017

Designed Spiroketal Protein Modulation

Divergent solid-phase synthesis of natural product-inspired bipartite cyclodepsipeptides: total synthesis of seragamide A.

artículo científico publicado en 2015

Dual-Input Regulation and Positional Control in Hybrid Oligonucleotide/Discotic Supramolecular Wires

artículo científico publicado en 2018

Dual-Input Regulation and Positional Control in Hybrid Oligonucleotide/Discotic Supramolecular Wires

Estrogen Receptor Folding Modulates cSrc Kinase SH2 Interaction via a Helical Binding Mode

artículo científico publicado en 2015

Fragmentation of organic ions bearing fixed multiple charges observed in MALDI MS.

artículo científico publicado en 2017

Generation of gas-phase ions from charged clusters: an important ionization step causing suppression of matrix and analyte ions in matrix-assisted laser desorption/ionization mass spectrometry

artículo científico publicado en 2016

Hydrophobicity determines the fate of self-assembled fluorescent nanoparticles in cells

artículo científico publicado en 2017

Immobilization of Ferrocene-Modified SNAP-Fusion Proteins

artículo científico publicado en 2013

Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes

artículo científico publicado en 2018

Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization

artículo científico

Ligand-Based Design of Allosteric Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Inverse Agonists

scientific article published on 24 December 2019

Metal-Free Photocatalytic Aerobic Oxidation of Thiols to Disulfides in Batch and Continuous-Flow

scholarly article by Ali Talla et al published 15 January 2015 in Advanced Synthesis & Catalysis

Modulators of protein-protein interactions

artículo científico publicado en 2014

Mutually Exclusive Cellular Uptake of Combinatorial Supramolecular Copolymers

artículo científico publicado en 2018

Natural-product-like spiroketals and fused bicyclic acetals as potential therapeutic agents for B-cell chronic lymphocytic leukaemia

artículo científico publicado en 2008

Optimizing charge state distribution is a prerequisite for accurate protein biomarker quantification with LC-MS/MS, as illustrated by hepcidin measurement

artículo científico publicado en 2018

Pharmaceutical implications of helix length control in helix-mediated protein-protein interactions.

artículo científico

Proline Primed Helix Length as a Modulator of the Nuclear Receptor–Coactivator Interaction ⬇️

artículo científico publicado el 7 de marzo de 2013

Relationship between Side-Chain Polarity and the Self-Assembly Characteristics of Perylene Diimide Derivatives in Aqueous Solution

artículo científico publicado en 2017

Selective chemical imaging of static actin in live cells

artículo científico publicado en 2012

Semisynthetic Bioluminescent Sensor Proteins for Direct Detection of Antibodies and Small Molecules in Solution.

artículo científico publicado en 2017

Stabilization and inhibition of protein-protein interactions: the 14-3-3 case study

artículo científico publicado en 2012

Stabilization of protein-protein interactions in drug discovery

artículo científico publicado en 2017

Stabilizer-Guided Inhibition of Protein-Protein Interactions

artículo científico publicado en 2015

Stabilizer-Guided Inhibition of Protein-Protein Interactions

Strong supramolecular control over protein self-assembly using a polyamine decorated β-cyclodextrin as synthetic recognition element

Structural interface between LRRK2 and 14-3-3 protein.

artículo científico publicado en 2017

Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein-protein interactions

scientific article published on 07 August 2020

Structure–activity relationship studies of miniproteins targeting the androgen receptor–coactivator interaction

Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin

scientific journal article

Supramolecular Chemistry Targeting Proteins.

artículo científico publicado en 2017

Supramolecular Control over Split-Luciferase Complementation

artículo científico publicado en 2016

Supramolecular Control over Split-Luciferase Complementation

Supramolecular control of cell adhesion via ferrocene–cucurbit[7]uril host–guest binding on gold surfaces

scientific article published on 01 May 2013

Synthesis and Self-Assembly of Bay-Substituted Perylene Diimide Gemini-Type Surfactants as Off-On Fluorescent Probes for Lipid Bilayers.

artículo científico publicado en 2018

Synthesis and structure-activity correlation of natural-product inspired cyclodepsipeptides stabilizing F-actin

artículo científico publicado en 2010

Targeting alpha-helix based protein interactions; nuclear receptors as a case study † † Funded by ERC grant 204554 – SupraChemBio

Tetrazine- trans-Cyclooctene Chemistry Applied to Fabricate Self-Assembled Fluorescent and Radioactive Nanoparticles for in Vivo Dual Mode Imaging

artículo científico publicado en 2019

The renaissance of Ras.

artículo científico publicado en 2014

Lista de obras de

A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14-3-3

A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14-3-3.

A Natural-Product Switch for a Dynamic Protein Interface

A Structural Study of the Cytoplasmic Chaperone Effect of 14-3-3 Proteins on Ataxin-1

A multi-gram-scale stereoselective synthesis of Z -endoxifen

A natural-product switch for a dynamic protein interface

A sample preparation method for recovering suppressed analyte ions in MALDI TOF MS.

A study on the effect of synthetic α-to-β3-amino acid mutations on the binding of phosphopeptides to 14-3-3 proteins

Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid-binding Globulins

Batch and Flow Synthesis of Disulfides by Visible-Light-Induced TiO2 Photocatalysis

Biophysical Characterization of Nucleophosmin Interactions with Human Immunodeficiency Virus Rev and Herpes Simplex Virus US11.

Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR.

Characterization of Coding/Noncoding Variants for SHROOM3 in Patients with CKD.

Chemical variation of natural product-like scaffolds: design and synthesis of spiroketal derivatives

Chemical variation of natural-product-like scaffolds: design, synthesis, and biological activity of fused bicyclic acetal derivatives

Communication: Probing the absolute configuration of chiral molecules at aqueous interfaces

Cooperativity basis for small-molecule stabilization of protein-protein interactions

Designed Spiroketal Protein Modulation

Designed Spiroketal Protein Modulation

Divergent solid-phase synthesis of natural product-inspired bipartite cyclodepsipeptides: total synthesis of seragamide A.

Dual-Input Regulation and Positional Control in Hybrid Oligonucleotide/Discotic Supramolecular Wires

Dual-Input Regulation and Positional Control in Hybrid Oligonucleotide/Discotic Supramolecular Wires

Estrogen Receptor Folding Modulates cSrc Kinase SH2 Interaction via a Helical Binding Mode

Fragmentation of organic ions bearing fixed multiple charges observed in MALDI MS.

Generation of gas-phase ions from charged clusters: an important ionization step causing suppression of matrix and analyte ions in matrix-assisted laser desorption/ionization mass spectrometry

Hydrophobicity determines the fate of self-assembled fluorescent nanoparticles in cells

Immobilization of Ferrocene-Modified SNAP-Fusion Proteins

Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes

Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization

Ligand-Based Design of Allosteric Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Inverse Agonists

Metal-Free Photocatalytic Aerobic Oxidation of Thiols to Disulfides in Batch and Continuous-Flow

Modulators of protein-protein interactions

Mutually Exclusive Cellular Uptake of Combinatorial Supramolecular Copolymers

Natural-product-like spiroketals and fused bicyclic acetals as potential therapeutic agents for B-cell chronic lymphocytic leukaemia

Optimizing charge state distribution is a prerequisite for accurate protein biomarker quantification with LC-MS/MS, as illustrated by hepcidin measurement

Pharmaceutical implications of helix length control in helix-mediated protein-protein interactions.

Proline Primed Helix Length as a Modulator of the Nuclear Receptor–Coactivator Interaction ⬇️

Relationship between Side-Chain Polarity and the Self-Assembly Characteristics of Perylene Diimide Derivatives in Aqueous Solution

Selective chemical imaging of static actin in live cells

Semisynthetic Bioluminescent Sensor Proteins for Direct Detection of Antibodies and Small Molecules in Solution.

Stabilization and inhibition of protein-protein interactions: the 14-3-3 case study

Stabilization of protein-protein interactions in drug discovery

Stabilizer-Guided Inhibition of Protein-Protein Interactions

Stabilizer-Guided Inhibition of Protein-Protein Interactions

Strong supramolecular control over protein self-assembly using a polyamine decorated β-cyclodextrin as synthetic recognition element

Structural interface between LRRK2 and 14-3-3 protein.

Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein-protein interactions

Structure–activity relationship studies of miniproteins targeting the androgen receptor–coactivator interaction

Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin

Supramolecular Chemistry Targeting Proteins.

Supramolecular Control over Split-Luciferase Complementation

Supramolecular Control over Split-Luciferase Complementation

Supramolecular control of cell adhesion via ferrocene–cucurbit[7]uril host–guest binding on gold surfaces

Synthesis and Self-Assembly of Bay-Substituted Perylene Diimide Gemini-Type Surfactants as Off-On Fluorescent Probes for Lipid Bilayers.

Synthesis and structure-activity correlation of natural-product inspired cyclodepsipeptides stabilizing F-actin

Targeting alpha-helix based protein interactions; nuclear receptors as a case study † † Funded by ERC grant 204554 – SupraChemBio

Tetrazine- trans-Cyclooctene Chemistry Applied to Fabricate Self-Assembled Fluorescent and Radioactive Nanoparticles for in Vivo Dual Mode Imaging

The renaissance of Ras.