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Antimicrobial peptide-inspired NH125 analogues: bacterial and fungal biofilm-eradicating agents and rapid killers of MRSA persisters.

artículo científico publicado en 2017

Combination Treatment of Erythromycin and Furamidine Provides Additive and Synergistic Rescue of Mis-Splicing in Myotonic Dystrophy Type 1 Models

artículo científico publicado en 2019

Halogenated quinolines bearing polar functionality at the 2-position: Identification of new antibacterial agents with enhanced activity against Staphylococcus epidermidis

artículo científico publicado en 2018

Halogenated quinolines discovered through reductive amination with potent eradication activities against MRSA, MRSE and VRE biofilms

artículo científico publicado en 2015

Harnessing the Chemistry of the Indole Heterocycle to Drive Discoveries in Biology and Medicine

artículo científico publicado en 2019

Instructive Advances in Chemical Microbiology Inspired by Nature's Diverse Inventory of Molecules

artículo científico publicado en 2020

Microwave-enhanced Friedländer synthesis for the rapid assembly of halogenated quinolines with antibacterial and biofilm eradication activities against drug resistant and tolerant bacteria

scientific article published on 27 July 2016

Molecular characterization of myotonic dystrophy fibroblast cell lines for use in small molecule screening

artículo científico publicado en 2022

Phenazine Antibiotic-Inspired Discovery of Bacterial Biofilm-Eradicating Agents

scientific article published on 02 October 2019

Preventing Morphine-Seeking Behavior through the Re-Engineering of Vincamine's Biological Activity

scientific article published on 23 March 2020

Rapid kill assessment of an N-arylated NH125 analogue against drug-resistant microorganisms

scientific article published on 29 January 2019

Re-Engineering of Yohimbine's Biological Activity through Ring Distortion: Identification and Structure-Activity Relationships of a New Class of Antiplasmodial Agents

scientific article published on 16 January 2020

Recent Progress in Natural-Product-Inspired Programs Aimed To Address Antibiotic Resistance and Tolerance

artículo científico publicado en 2019

Targeting bacterial biofilms with persister-killing agents

artículo científico publicado en 2020

The Path to New Halogenated Quinolines With Enhanced Activities Against

article

Transcript Profiling of MRSA Biofilms Treated with a Halogenated Phenazine Eradicating Agent: A Platform for Defining Cellular Targets and Pathways Critical to Biofilm Survival

artículo científico publicado en 2018