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3-Hydroxyphthalic Anhydride- Modified Rabbit Anti-PAP IgG as a Potential Bifunctional HIV-1 Entry Inhibitor.

artículo científico publicado en 2018

3-Hydroxyphthalic anhydride-modified human serum albumin as a microbicide candidate inhibits HIV infection by blocking viral entry

article

3-hydroxyphthalic anhydride-modified chicken ovalbumin exhibits potent and broad anti-HIV-1 activity: a potential microbicide for preventing sexual transmission of HIV-1

artículo científico publicado en 2010

3-hydroxyphthalic anhydride-modified human serum albumin as a microbicide candidate against HIV type 1 entry by targeting both viral envelope glycoprotein gp120 and cellular receptor CD4.

artículo científico publicado en 2013

A 219-mer CHO-expressing receptor-binding domain of SARS-CoV S protein induces potent immune responses and protective immunity

artículo científico publicado en 2010

A CCR5 antagonist-based HIV entry inhibitor exhibited potent spermicidal activity: Potential application for contraception and prevention of HIV sexual transmission

artículo científico publicado en 2018

A Degraded Fragment of HIV-1 Gp120 in Rat Hepatocytes Forms Fibrils and Enhances HIV-1 Infection

artículo científico publicado en 2017

A Human DPP4-Knockin Mouse's Susceptibility to Infection by Authentic and Pseudotyped MERS-CoV

scholarly article by Changfa Fan published in August 2018

A Novel CXCR4 Targeting Protein SDF-1/54 as an HIV-1 Entry Inhibitor

artículo científico publicado en 2019

A Novel Chimeric Protein-based HIV-1 Fusion Inhibitor Targeting gp41 Glycoprotein with High Potency and Stability ⬇️

artículo científico publicado el 20 de junio de 2011

A Novel Nanobody Targeting Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Receptor-Binding Domain Has Potent Cross-Neutralizing Activity and Protective Efficacy against MERS-CoV

scholarly article by Guangyu Zhao published in September 2018

A Peptide Derived from the HIV-1 gp120 Coreceptor-Binding Region Promotes Formation of PAP248-286 Amyloid Fibrils to Enhance HIV-1 Infection

artículo científico publicado en 2015

A Peptide-Based HIV-1 Fusion Inhibitor with Two Tail-Anchors and Palmitic Acid Exhibits Substantially Improved In Vitro and Ex Vivo Anti-HIV-1 Activity and Prolonged In Vivo Half-Life

article

A Recombinant Vaccine of H5N1 HA1 Fused with Foldon and Human IgG Fc Induced Complete Cross-Clade Protection against Divergent H5N1 Viruses ⬇️

artículo científico publicado el 27 de enero de 2011

A bivalent recombinant protein inactivates HIV-1 by targeting the gp41 prehairpin fusion intermediate induced by CD4 D1D2 domains

artículo científico publicado en 2012

A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in Middle East respiratory syndrome coronavirus spike protein.

artículo científico publicado en 2014

A critical HA1 neutralizing domain of H5N1 influenza in an optimal conformation induces strong cross-protection

artículo científico publicado en 2013

A defucosylated bispecific multivalent molecule exhibits broad HIV-1-neutralizing activity and enhanced antibody-dependent cellular cytotoxicity against reactivated HIV-1 latently infected cells

article

A nanoparticle-encapsulated non-nucleoside reverse-transcriptase inhibitor with enhanced anti-HIV-1 activity and prolonged circulation time in plasma

artículo científico publicado en 2015

A natural theaflavins preparation inhibits HIV-1 infection by targeting the entry step: potential applications for preventing HIV-1 infection

artículo científico publicado en 2011

A new role of neuraminidase (NA) in the influenza virus life cycle: implication for developing NA inhibitors with novel mechanism of action

artículo científico publicado en 2016

A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice, rabbits and NHPs

artículo científico publicado en 2022

A novel bispecific peptide HIV-1 fusion inhibitor targeting the N-terminal heptad repeat and fusion peptide domains in gp41.

artículo científico publicado en 2016

A novel strategy for rapid construction of libraries of full-length antibodies highly expressed on mammalian cell surfaces

artículo científico publicado en 2010

A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike

artículo científico publicado en 2019

A peptide-based viral inactivator inhibits Zika virus infection in pregnant mice and fetuses

artículo científico publicado en 2017

A predicted receptor-binding and critical neutralizing domain in S protein of the novel human coronavirus HCoV-EMC.

artículo científico publicado en 2012

A randomized open-label clinical trial of an anti-HPV biological dressing (JB01-BD) administered intravaginally to treat high-risk HPV infection

artículo científico publicado en 2015

A recombinant mimetics of the HIV-1 gp41 prehairpin fusion intermediate fused with human IgG Fc fragment elicits neutralizing antibody response in the vaccinated mice

artículo científico publicado en 2010

A recombinant protein containing highly conserved hemagglutinin residues 81-122 of influenza H5N1 induces strong humoral and mucosal immune responses

artículo científico publicado en 2013

A recombinant receptor-binding domain of MERS-CoV in trimeric form protects human dipeptidyl peptidase 4 (hDPP4) transgenic mice from MERS-CoV infection

artículo científico publicado en 2016

A safe and convenient pseudovirus-based inhibition assay to detect neutralizing antibodies and screen for viral entry inhibitors against the novel human coronavirus MERS-CoV

artículo científico publicado en 2013

A single amino acid substitution (R441A) in the receptor-binding domain of SARS coronavirus spike protein disrupts the antigenic structure and binding activity

scientific article published on 30 March 2006

A stereo configuration-activity study of 3-iodo-4-(2-methylcyclohexyloxy)-6-phenethylpyridin-2(2H)-ones as potency inhibitors of HIV-1 variants

artículo científico publicado en 2015

A suspicious role of interferon in the pathogenesis of SARS-CoV-2 by enhancing expression of ACE2

scientific article published on 21 May 2020

A truncated receptor-binding domain of MERS-CoV spike protein potently inhibits MERS-CoV infection and induces strong neutralizing antibody responses: implication for developing therapeutics and vaccines

artículo científico publicado en 2013

ADS-J1 inhibits HIV-1 infection and membrane fusion by targeting the highly conserved pocket in the gp41 NHR-trimer

artículo científico publicado en 2014

ADS-J1 inhibits human immunodeficiency virus type 1 entry by interacting with the gp41 pocket region and blocking fusion-active gp41 core formation

artículo científico publicado en 2009

ADS-J1 inhibits semen-derived amyloid fibril formation and blocks fibril-mediated enhancement of HIV-1 infection.

artículo científico publicado en 2015

Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy

scientific article published on 30 July 2020

Adenovirus-based vaccines against avian-origin H5N1 influenza viruses.

artículo científico publicado en 2014

Advancements in Developing Strategies for Sterilizing and Functional HIV Cures.

artículo científico publicado en 2017

Advancements in the development of subunit influenza vaccines

artículo científico publicado en 2015

Advances in MERS-CoV Vaccines and Therapeutics Based on the Receptor-Binding Domain

scientific article published in 2019

Advances in the research and development of therapeutic antibodies against the Zika virus.

artículo científico publicado en 2018

An Amphiphilic Conjugate Approach toward the Design and Synthesis of Betulinic Acid–Polyphenol Conjugates as Inhibitors of the HIV‐1 gp41 Fusion Core Formation ⬇️

artículo científico publicado el 17 de junio de 2011

An H5N1 M2e-based multiple antigenic peptide vaccine confers heterosubtypic protection from lethal infection with pandemic 2009 H1N1 virus

artículo científico publicado en 2010

An M2e-based multiple antigenic peptide vaccine protects mice from lethal challenge with divergent H5N1 influenza viruses.

artículo científico publicado en 2010

An amphipathic peptide targeting the gp41 cytoplasmic tail kills HIV-1 virions and infected cells

scientific article published on 01 June 2020

An effective strategy for recapitulating N-terminal heptad repeat trimers in enveloped virus surface glycoproteins for therapeutic applications.

artículo científico publicado en 2015

An emerging coronavirus causing pneumonia outbreak in Wuhan, China: calling for developing therapeutic and prophylactic strategies

scientific article published on 31 January 2020

An engineered HIV-1 gp41 trimeric coiled coil with increased stability and anti-HIV-1 activity: implication for developing anti-HIV microbicides

artículo científico publicado en 2013

An immunogen containing four tandem 10E8 epitope repeats with exposed key residues induces antibodies that neutralize HIV-1 and activates an ADCC reporter gene

artículo científico publicado en 2016

Anti-HIV agents inspired by antibodies

artículo científico publicado en 2020

Anti-HIV antibody and drug combinations exhibit synergistic activity against drug-resistant HIV-1 strains

artículo científico publicado en 2017

Anti-HIV-1 activity of cellulose acetate phthalate: synergy with soluble CD4 and induction of "dead-end" gp41 six-helix bundles

artículo científico publicado en 2002

Antibodies induced by receptor-binding domain in spike protein of SARS-CoV do not cross-neutralize the novel human coronavirus hCoV-EMC.

artículo científico publicado en 2013

Antigenic and immunogenic characterization of recombinant baculovirus-expressed severe acute respiratory syndrome coronavirus spike protein: implication for vaccine design

artículo científico publicado en 2006

Antigenic properties of a transport-competent influenza HA/HIV Env chimeric protein

scientific article published on 24 May 2006

Antigenicity and immunogenicity of SARS-CoV S protein receptor-binding domain stably expressed in CHO cells

scientific article published on 05 May 2009

Approaches for identification of HIV-1 entry inhibitors targeting gp41 pocket

artículo científico publicado en 2013

Artificial peptides conjugated with cholesterol and pocket-specific small molecules potently inhibit infection by laboratory-adapted and primary HIV-1 isolates and enfuvirtide-resistant HIV-1 strains

artículo científico publicado en 2014

Association of candidate susceptible loci with chronic infection with hepatitis B virus in a Chinese population

article

Automatic quantitation of HIV-1 mediated cell-to-cell fusion with a digital image analysis system (DIAS): application for rapid screening of HIV-1 fusion inhibitors

artículo científico publicado en 2003

Binding of the 2F5 monoclonal antibody to native and fusion-intermediate forms of human immunodeficiency virus type 1 gp41: implications for fusion-inducing conformational changes.

artículo científico publicado en 2004

Biosecurity and biosafety in research on emerging pathogens

artículo científico publicado en 2012

Blockade of the C5a-C5aR axis alleviates lung damage in hDPP4-transgenic mice infected with MERS-CoV.

artículo científico publicado en 2018

Broad-Spectrum Coronavirus Fusion Inhibitors to Combat COVID-19 and Other Emerging Coronavirus Diseases

scientific article published on 28 May 2020

CL-385319 inhibits H5N1 avian influenza A virus infection by blocking viral entry

artículo científico publicado en 2011

Calling for rapid development of a safe and effective MERS vaccine

artículo científico publicado en 2014

Cell Entry of Porcine Epidemic Diarrhea Coronavirus Is Activated by Lysosomal Proteases.

artículo científico publicado en 2016

Characterization and Demonstration of the Value of a Lethal Mouse Model of Middle East Respiratory Syndrome Coronavirus Infection and Disease

artículo científico publicado en 2015

Chemically Modified Human Serum Albumin Potently Blocks Entry of Ebola Pseudoviruses and Viruslike Particles

artículo científico publicado en 2017

Chemically modified bovine beta-lactoglobulin inhibits human papillomavirus infection

artículo científico publicado en 2013

Chemoenzymatic synthesis of HIV-1 gp41 glycopeptides: effects of glycosylation on the anti-HIV activity and alpha-helix bundle-forming ability of peptide C34.

artículo científico publicado en 2005

China needs safe and effective microbicides for preventing sexual transmission of HIV.

artículo científico publicado en 2006

Cleavage of spike protein of SARS coronavirus by protease factor Xa is associated with viral infectivity

artículo científico publicado en 2007

Co-delivery of HIV-1 entry inhibitor and nonnucleoside reverse transcriptase inhibitor shuttled by nanoparticles: cocktail therapeutic strategy for antiviral therapy.

artículo científico publicado en 2015

Combating flu in China

artículo científico publicado en 2017

Combating the emerging viral infectious diseases

artículo científico publicado en 2014

Combination of candidate microbicides cellulose acetate 1,2-benzenedicarboxylate and UC781 has synergistic and complementary effects against human immunodeficiency virus type 1 infection

artículo científico publicado en 2005

Combinations of 3-hydroxyphthalic anhydride-modified ovalbumin with antiretroviral drug-based microbicide candidates display synergistic and complementary effects against HIV-1 infection

artículo científico publicado en 2011

Combinations of the first and next generations of human immunodeficiency virus (HIV) fusion inhibitors exhibit a highly potent synergistic effect against enfuvirtide- sensitive and -resistant HIV type 1 strains

artículo científico publicado en 2009

Combining New Non-Nucleoside Reverse Transcriptase Inhibitors (RTIs) with AZT Results in Strong Synergism against Multi-RTI-Resistant HIV-1 Strains

article

Combining a Fusion Inhibitory Peptide Targeting the MERS-CoV S2 Protein HR1 Domain and a Neutralizing Antibody Specific for the S1 Protein Receptor-Binding Domain (RBD) Showed Potent Synergism against Pseudotyped MERS-CoV with or without Mutations in

artículo científico publicado en 2019

Combining metformin and nelfinavir exhibits synergistic effects against the growth of human cervical cancer cells and xenograft in nude mice

artículo científico publicado en 2017

Complement Inhibition Alleviates Paraquat-Induced Acute Lung Injury ⬇️

artículo científico publicado el 18 de marzo de 2011

Conjugation of a nonspecific antiviral sapogenin with a specific HIV fusion inhibitor: a promising strategy for discovering new antiviral therapeutics

artículo científico publicado en 2014

Conserved residue Lys574 in the cavity of HIV-1 Gp41 coiled-coil domain is critical for six-helix bundle stability and virus entry.

artículo científico publicado en 2007

Conserved salt bridge between the N- and C-terminal heptad repeat regions of the human immunodeficiency virus type 1 gp41 core structure is critical for virus entry and inhibition

artículo científico publicado en 2008

Construction of personalized full-length fully human mammalian display antibody library for children with systemic lupus erythematosus

artículo científico publicado el 1 de agosto de 2012

Controlling HIV sexual transmission: a major challenge for China's new leadership

artículo científico publicado en 2013

CorMut: an R/Bioconductor package for computing correlated mutations based on selection pressure

artículo científico publicado en 2014

Correction: A Peptide Derived from the HIV-1 gp120 Coreceptor-Binding Region Promotes Formation of PAP248-286 Amyloid Fibrils to Enhance HIV-1 Infection

artículo científico publicado en 2016

Correction: HIV-1 Fusion Is Blocked through Binding of GB Virus C E2D Peptides to the HIV-1 gp41 Disulfide Loop.

artículo científico publicado en 2014

Creating an Artificial Tail Anchor as a Novel Strategy To Enhance the Potency of Peptide-Based HIV Fusion Inhibitors.

scientific article published on 19 October 2016

Critical neutralizing fragment of Zika virus EDIII elicits cross-neutralization and protection against divergent Zika viruses

artículo científico publicado en 2018

Cross-neutralization of SARS coronavirus-specific antibodies against bat SARS-like coronaviruses.

artículo científico publicado en 2017

Cross-neutralization of human and palm civet severe acute respiratory syndrome coronaviruses by antibodies targeting the receptor-binding domain of spike protein

artículo científico publicado en 2006

Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens

artículo científico publicado en 2008

Current Progress in the Development of Zika Virus Vaccines

artículo científico publicado en 2021

Current advancements and potential strategies in the development of MERS-CoV vaccines

artículo científico publicado en 2014

De Novo Design of α-Helical Lipopeptides Targeting Viral Fusion Proteins: A Promising Strategy for Relatively Broad-Spectrum Antiviral Drug Discovery

artículo científico publicado en 2018

De novo design of isopeptide bond-tethered triple-stranded coiled coils with exceptional resistance to unfolding and proteolysis: implication for developing antiviral therapeutics

scientific article published on 06 August 2015

Deletion of fusion peptide or destabilization of fusion core of HIV gp41 enhances antigenicity and immunogenicity of 4E10 epitope

artículo científico publicado en 2008

Design and evaluation of sifuvirtide, a novel HIV-1 fusion inhibitor

artículo científico publicado en 2008

Design of a protein surface antagonist based on alpha-helix mimicry: inhibition of gp41 assembly and viral fusion

artículo científico publicado en 2002

Design of highly potent HIV fusion inhibitors based on artificial peptide sequences

artículo científico publicado en 2012

Design, Synthesis, and Biological Activity of Novel 5-((Arylfuran/1H-pyrrol-2-yl)methylene)-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-4-ones as HIV-1 Fusion Inhibitors Targeting gp41 ⬇️

artículo científico publicado el 29 de diciembre de 2010

Design, Synthesis, and Biological Evaluation of 1-[(2-Benzyloxyl/alkoxyl)methyl]-5-halo-6-aryluracils as Potent HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with an Improved Drug Resistance Profile ⬇️

artículo científico publicado el 17 de febrero de 2012

Design, Synthesis, and Evaluation of Diarylpyridines and Diarylanilines as Potent Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors ⬇️

artículo científico publicado el 4 de noviembre de 2010

Design, synthesis and biological evaluation of 3-substituted 2,5-dimethyl-N-(3-(1H-tetrazol-5-yl)phenyl)pyrroles as novel potential HIV-1 gp41 inhibitors.

artículo científico publicado en 2011

Design, synthesis, and biological activity of a novel series of 2,5-disubstituted furans/pyrroles as HIV-1 fusion inhibitors targeting gp41 ⬇️

artículo científico publicado el 5 de septiembre de 2011

Design, synthesis, and biological activity of novel 1,4-disubstituted piperidine/piperazine derivatives as CCR5 antagonist-based HIV-1 entry inhibitors.

artículo científico publicado en 2012

Design, synthesis, and biological evaluation of N-carboxyphenylpyrrole derivatives as potent HIV fusion inhibitors targeting gp41

artículo científico publicado en 2008

Design, synthesis, and biological evaluation of highly potent small molecule-peptide conjugates as new HIV-1 fusion inhibitors.

artículo científico publicado en 2013

Design, synthesis, and structure-activity relationship of a novel series of 2-aryl 5-(4-oxo-3-phenethyl-2-thioxothiazolidinylidenemethyl)furans as HIV-1 entry inhibitors

artículo científico publicado en 2009

Determination of the HIV-1 gp41 fusogenic core conformation modeled by synthetic peptides: applicable for identification of HIV-1 fusion inhibitors

scientific article published on 01 September 2003

Development and preclinical studies of broad-spectrum anti-HIV agent (3'R,4'R)-3-cyanomethyl-4-methyl-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone (3-cyanomethyl-4-methyl-DCK).

scientific article published on December 2008

Development of Peptide and Small‐Molecule HIV‐1 Fusion Inhibitors that Target gp41 ⬇️

artículo científico publicado el 8 de noviembre de 2010

Development of SARS vaccines and therapeutics is still needed

article

Development of Small-Molecule MERS-CoV Inhibitors

article

Development of Small-molecule HIV Entry Inhibitors Specifically Targeting gp120 or gp41

artículo científico publicado en 2015

Development of a cell-based enzyme-linked immunosorbent assay for high-throughput screening of HIV type 1 entry inhibitors targeting the coreceptor CXCR4.

artículo científico publicado en 2003

Development of a heat-stable and orally delivered recombinant M2e-expressing B. subtilis spore-based influenza vaccine

artículo científico publicado en 2014

Development of a safe and convenient neutralization assay for rapid screening of influenza HA-specific neutralizing monoclonal antibodies

artículo científico publicado en 2010

Development of human neutralizing monoclonal antibodies for prevention and therapy of MERS-CoV infections

artículo científico publicado en 2014

Development of subunit vaccines against severe acute respiratory syndrome

artículo científico publicado en 2008

Development of therapeutics for treatment of Ebola virus infection.

artículo científico publicado en 2014

Development of variant‐proof severe acute respiratory syndrome coronavirus 2, pan‐sarbecovirus, and pan‐β‐coronavirus vaccines

artículo científico publicado en 2022

Diarylaniline derivatives as a distinct class of HIV-1 non-nucleoside reverse transcriptase inhibitors

artículo científico publicado en 2010

Differences in the pathogenicity and inflammatory responses induced by avian influenza A/H7N9 virus infection in BALB/c and C57BL/6 mouse models

artículo científico publicado en 2014

Different from the HIV fusion inhibitor C34, the anti-HIV drug Fuzeon (T-20) inhibits HIV-1 entry by targeting multiple sites in gp41 and gp120.

artículo científico publicado en 2005

Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide

artículo científico publicado en 2007

Discovery of a potent peptidic cyclophilin A inhibitor Trp-Gly-Pro ⬇️

artículo científico publicado el 22 de febrero de 2011

Discovery of diarylpyridine derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors

scientific article published on 19 July 2009

Double insult: flu bug enhances SARS-CoV-2 infectivity

artículo científico publicado en 2021

Drug-resistant viruses may repair impaired fitness by mutations outside the drug target site

artículo científico publicado en 2009

E14-F55 combination in M2 protein: a putative molecular determinant responsible for swine-origin influenza A virus transmission in humans.

artículo científico publicado en 2009

Efficacy, Stability, and Biosafety of Sifuvirtide Gel as a Microbicide Candidate against HIV-1 ⬇️

artículo científico publicado el 16 de mayo de 2012

Engineered trimeric ACE2 binds viral spike protein and locks it in "Three-up" conformation to potently inhibit SARS-CoV-2 infection

artículo científico publicado en 2020

Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen

artículo científico publicado en 2018

Erratum to: Genome-wide analysis of an avirulent strain that induces protective immunity against challenge with virulent Streptococcus Suis serotype 2.

artículo científico publicado en 2017

Erratum to: Immunogenicity and antigenic relationships among spike proteins of porcine epidemic diarrhea virus subtypes G1 and G2.

artículo científico publicado en 2016

Escape from humoral immunity is associated with treatment failure in HIV-1-infected patients receiving long-term antiretroviral therapy.

artículo científico publicado en 2017

Evaluation of "credit card" libraries for inhibition of HIV-1 gp41 fusogenic core formation

artículo científico publicado en 2006

Evaluation of recombinant Onchocerca volvulus activation associated protein-1 (ASP-1) as a potent Th1-biased adjuvant with a panel of protein or peptide-based antigens and commercial inactivated vaccines

artículo científico publicado en 2008

Exceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodies.

artículo científico publicado en 2014

F(ab')2 fragment of a gp41 NHR-trimer-induced IgM monoclonal antibody neutralizes HIV-1 infection and blocks viral fusion by targeting the conserved gp41 pocket

artículo científico publicado en 2013

Fab crystallization and preliminary X-ray analysis of NC-1, an anti-HIV-1 antibody that recognizes the six-helix bundle core of gp41.

artículo científico publicado en 2010

FbaA- and M protein-based multi-epitope vaccine elicits strong protective immune responses against group A streptococcus in mouse model

artículo científico publicado en 2014

Four-way ligation for construction of a mammalian cell-based full-length antibody display library ⬇️

artículo científico publicado el 21 de enero de 2011

From therapeutic antibodies to chimeric antigen receptors (CARs): making better CARs based on antigen-binding domain.

artículo científico publicado en 2016

Genome-wide analysis of a avirulent and reveal the strain induces pro-tective immunity against challenge with virulent Streptococcus suis Serotype 2.

artículo científico publicado en 2017

Genomic signature and mutation trend analysis of pandemic (H1N1) 2009 influenza A virus

artículo científico publicado en 2010

Genomic signature and protein sequence analysis of a novel influenza A (H7N9) virus that causes an outbreak in humans in China

artículo científico publicado en 2013

Griffithsin with A Broad-Spectrum Antiviral Activity by Binding Glycans in Viral Glycoprotein Exhibits Strong Synergistic Effect in Combination with A Pan-Coronavirus Fusion Inhibitor Targeting SARS-CoV-2 Spike S2 Subunit

artículo científico publicado en 2020

HIV entry inhibitors targeting gp41: from polypeptides to small-molecule compounds

artículo científico publicado en 2007

HIV gp41 C-terminal heptad repeat contains multifunctional domains. Relation to mechanisms of action of anti-HIV peptides

artículo científico publicado en 2007

HIV type 1 B'/C recombinant (CRF07_BC) in virologic noncontrollers elicits neutralizing antibodies against heterologous but not autologous viruses

artículo científico publicado en 2010

HIV-1 fusion is blocked through binding of GB Virus C E2-derived peptides to the HIV-1 gp41 disulfide loop [corrected]

artículo científico publicado en 2013

HIV-1 glycoprotein 41 ectodomain induces activation of the CD74 protein-mediated extracellular signal-regulated kinase/mitogen-activated protein kinase pathway to enhance viral infection

artículo científico publicado en 2011

HIV-1 gp41 Core with Exposed Membrane-Proximal External Region Inducing Broad HIV-1 Neutralizing Antibodies ⬇️

artículo científico publicado el 31 de marzo de 2011

HIV-1 gp41 ectodomain enhances Cryptococcus neoformans binding to HBMEC.

artículo científico publicado en 2007

HIV-1 gp41 ectodomain enhances Cryptococcus neoformans binding to human brain microvascular endothelial cells via gp41 core-induced membrane activities ⬇️

artículo científico publicado el 15 de septiembre de 2011

HIV-1 gp41 fusion intermediate: a target for HIV therapeutics

artículo científico publicado en 2010

HIV-1 gp41-targeting fusion inhibitory peptides enhance the gp120-targeting protein-mediated inactivation of HIV-1 virions

artículo científico publicado en 2017

HIV-1 impairs human retinal pigment epithelial barrier function: possible association with the pathogenesis of HIV-associated retinopathy.

artículo científico publicado en 2014

HIV-1 variants with a single-point mutation in the gp41 pocket region exhibiting different susceptibility to HIV fusion inhibitors with pocket- or membrane-binding domain

artículo científico publicado en 2012

HIV-associated dementia in the era of highly active antiretroviral therapy (HAART) ⬇️

artículo científico publicado el 22 de enero de 2011

Heteromeric Assembled Polypeptidic Artificial Hydrolases with a Six‐Helical Bundle Scaffold ⬇️

artículo científico publicado el 29 de septiembre de 2011

High genetic and antigenic similarity between a swine H3N2 influenza A virus and a prior human influenza vaccine virus: a possible immune pressure-driven cross-species transmission.

artículo científico publicado en 2009

High throughput screening and characterization of HIV-1 entry inhibitors targeting gp41: theories and techniques

artículo científico publicado en 2004

Highly pathogenic avian influenza A(H5N1) mutants transmissible by air are susceptible to human and animal neutralizing antibodies

artículo científico publicado en 2013

Hydrophobic mutations in buried polar residues enhance HIV-1 gp41 N-terminal heptad repeat-C-terminal heptad repeat interactions and C-peptides' anti-HIV activity

artículo científico publicado en 2014

Identification and characterization of novel neutralizing epitopes in the receptor-binding domain of SARS-CoV spike protein: revealing the critical antigenic determinants in inactivated SARS-CoV vaccine

artículo científico publicado en 2006

Identification and structural characterization of a broadly neutralizing antibody targeting a novel conserved epitope on the influenza virus H5N1 hemagglutinin

artículo científico publicado en 2012

Identification of HBsAg-specific antibodies from a mammalian cell displayed full-length human antibody library of healthy immunized donor ⬇️

artículo científico publicado el 19 de diciembre de 2011

Identification of N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4.

artículo científico publicado en 2005

Identification of a D-amino acid decapeptide HIV-1 entry inhibitor

artículo científico publicado en 2006

Identification of a critical motif for the human immunodeficiency virus type 1 (HIV-1) gp41 core structure: implications for designing novel anti-HIV fusion inhibitors

artículo científico publicado en 2008

Identification of a critical neutralization determinant of severe acute respiratory syndrome (SARS)-associated coronavirus: importance for designing SARS vaccines

scientific article published on 01 March 2005

Identification of a gp41 core-binding molecule with homologous sequence of human TNNI3K-like protein as a novel human immunodeficiency virus type 1 entry inhibitor

artículo científico publicado en 2010

Identification of a human protein-derived HIV-1 fusion inhibitor targeting the gp41 fusion core structure.

artículo científico publicado en 2013

Identification of a receptor-binding domain in the S protein of the novel human coronavirus Middle East respiratory syndrome coronavirus as an essential target for vaccine development

artículo científico publicado en 2013

Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirus.

artículo científico publicado en 2015

Identification of critical antibody-binding sites in the HIV-1 gp41 six-helix bundle core as potential targets for HIV-1 fusion inhibitors

artículo científico publicado en 2008

Identification of immunodominant epitopes on the membrane protein of the severe acute respiratory syndrome-associated coronavirus

artículo científico publicado en 2005

Identification of immunodominant sites on the spike protein of severe acute respiratory syndrome (SARS) coronavirus: implication for developing SARS diagnostics and vaccines

artículo científico publicado en 2004

Identification of inhibitors of the HIV-1 gp41 six-helix bundle formation from extracts of Chinese medicinal herbs Prunella vulgaris and Rhizoma cibotte

artículo científico publicado en 2002

Identification of the HIV-1 gp41 core-binding motif in the scaffolding domain of caveolin-1.

artículo científico publicado en 2006

Identification of the HIV-1 gp41 core-binding motif--HXXNPF.

artículo científico publicado en 2006

Identification of the critical sites of NNRTI-resistance in reverse transcriptase of HIV-1 CRF_BC strains

artículo científico publicado en 2014

IgG Fc-binding motif-conjugated HIV-1 fusion inhibitor exhibits improved potency and in vivo half-life: Potential application in combination with broad neutralizing antibodies

scientific article published on 05 December 2019

Immunogenicity and antigenic relationships among spike proteins of porcine epidemic diarrhea virus subtypes G1 and G2.

artículo científico publicado en 2015

Improved Pharmacological and Structural Properties of HIV Fusion Inhibitor AP3 over Enfuvirtide: Highlighting Advantages of Artificial Peptide Strategy

artículo científico publicado en 2015

Improving the CH1-CK heterodimerization and pharmacokinetics of 4Dm2m, a novel potent CD4-antibody fusion protein against HIV-1.

artículo científico publicado en 2016

In silico design of a DNA-based HIV-1 multi-epitope vaccine for Chinese populations

artículo científico publicado en 2015

In vitro selection and characterization of HIV-1 variants with increased resistance to sifuvirtide, a novel HIV-1 fusion inhibitor ⬇️

artículo científico publicado el 23 de noviembre de 2010

In-Depth Analysis of Human Neonatal and Adult IgM Antibody Repertoires

artículo científico publicado en 2018

Inactivated SARS-CoV vaccine elicits high titers of spike protein-specific antibodies that block receptor binding and virus entry

artículo científico publicado en 2004

Induction of protection against divergent H5N1 influenza viruses using a recombinant fusion protein linking influenza M2e to Onchocerca volvulus activation associated protein-1 (ASP-1) adjuvant ⬇️

artículo científico publicado el 21 de agosto de 2010

Inefficiency of Sera from Mice Treated with Pseudotyped SARS-CoV to Neutralize 2019-nCoV Infection

scientific article published on 31 March 2020

Inhibition of complement activation alleviates acute lung injury induced by highly pathogenic avian influenza H5N1 virus infection

artículo científico publicado en 2013

Interaction of HIV-1 gp41 core with NPF motif in Epsin: implication in endocytosis of HIV

artículo científico publicado en 2008

Interactions between different generation HIV‐1 fusion inhibitors and the putative mechanism underlying the synergistic anti‐HIV‐1 effect resulting from their combination ⬇️

artículo científico publicado el 15 de noviembre de 2011

Intranasal administration of maleic anhydride-modified human serum albumin for pre-exposure prophylaxis of respiratory syncytial virus infection

artículo científico publicado en 2015

Intranasal application of polyethyleneimine suppresses influenza virus infection in mice

artículo científico publicado en 2016

Intranasal vaccination of recombinant H5N1 HA1 proteins fused with foldon and Fc induces strong mucosal immune responses with neutralizing activity: Implication for developing novel mucosal influenza vaccines

artículo científico publicado en 2015

Intranasal vaccination of recombinant adeno-associated virus encoding receptor-binding domain of severe acute respiratory syndrome coronavirus (SARS-CoV) spike protein induces strong mucosal immune responses and provides long-term protection against

artículo científico publicado en 2008

Intranasal vaccination with recombinant receptor-binding domain of MERS-CoV spike protein induces much stronger local mucosal immune responses than subcutaneous immunization: Implication for designing novel mucosal MERS vaccines.

artículo científico publicado en 2014

Introduction of neutralizing immunogenicity index to the rational design of MERS coronavirus subunit vaccines

artículo científico publicado en 2016

Isolation of Anti-HIV Components fromCanarium albumFruits by High-Speed Counter-Current Chromatography

article

Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody.

artículo científico publicado en 2015

L-Selectin and P-Selectin Are Novel Biomarkers of Cervicovaginal Inflammation for Preclinical Mucosal Safety Assessment of Anti-HIV-1 Microbicide ⬇️

artículo científico publicado el 5 de marzo de 2012

Learning from the past: development of safe and effective COVID-19 vaccines

artículo científico publicado en 2020

Long-Acting HIV-1 Fusion Inhibitory Peptides and their Mechanisms of Action

scientific article published on 02 September 2019

MERS-CoV spike protein: a key target for antivirals

artículo científico publicado en 2016

Maleic anhydride-modified chicken ovalbumin as an effective and inexpensive anti-HIV microbicide candidate for prevention of HIV sexual transmission

artículo científico publicado en 2010

Mapping of antigenic sites on the nucleocapsid protein of the severe acute respiratory syndrome coronavirus

artículo científico publicado en 2004

Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China

artículo científico publicado en 2020

Microbicides: stopping HIV at the gate

artículo científico publicado en 2006

Middle East respiratory syndrome coronavirus (MERS-CoV) entry inhibitors targeting spike protein.

artículo científico publicado en 2014

Middle East respiratory syndrome: current status and future prospects for vaccine development

artículo científico publicado en 2015

Modulation of HBV replication by microRNA-15b through targeting hepatocyte nuclear factor 1α

artículo científico publicado en 2014

Molecular modeling studies of N-substituted pyrrole derivatives--potential HIV-1 gp41 inhibitors

artículo científico publicado en 2008

Multi-Organ Damage in Human Dipeptidyl Peptidase 4 Transgenic Mice Infected with Middle East Respiratory Syndrome-Coronavirus

artículo científico publicado en 2015

Mutation covariation of HIV-1 CRF07_BC reverse transcriptase during antiretroviral therapy

artículo científico publicado en 2013

Mutations of Gln64 in the HIV-1 gp41 N-Terminal Heptad Repeat Render Viruses Resistant to Peptide HIV Fusion Inhibitors Targeting the gp41 Pocket ⬇️

artículo científico publicado el 19 de octubre de 2011

N-substituted pyrrole derivatives as novel human immunodeficiency virus type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus fusion

artículo científico publicado en 2004

Nelfinavir, an HIV protease inhibitor, induces apoptosis and cell cycle arrest in human cervical cancer cells via the ROS-dependent mitochondrial pathway

artículo científico publicado en 2015

Neutralization sensitivity of HIV-1 subtype B' clinical isolates from former plasma donors in China

artículo científico publicado en 2013

No evidence for a superior platform to develop therapeutic antibodies rapidly in response to MERS-CoV and other emerging viruses.

artículo científico publicado en 2015

Normal human sera contain heat-sensitive factor(s) to enhance H7N9 influenza virus infection

artículo científico publicado en 2015

Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitor Agents: Optimization of Diarylanilines with High Potency against Wild-Type and Rilpivirine-Resistant E138K Mutant Virus

artículo científico publicado en 2016

Novel anti-HIV peptides containing multiple copies of artificially designed heptad repeat motifs

artículo científico publicado en 2008

Novel pyridinone derivatives as non-nucleoside reverse transcriptase inhibitors (NNRTIs) with high potency against NNRTI-resistant HIV-1 strains

artículo científico publicado en 2013

Novel recombinant engineered gp41 N-terminal heptad repeat trimers and their potential as anti-HIV-1 therapeutics or microbicides

artículo científico publicado en 2010

Optimization of antigen dose for a receptor-binding domain-based subunit vaccine against MERS coronavirus

artículo científico publicado en 2015

Optimization of the antiviral potency and lipophilicity of halogenated 2,6-diarylpyridinamines as a novel class of HIV-1 NNRTIS.

artículo científico publicado en 2014

Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways

artículo científico publicado en 2004

PA-356R is a unique signature of the avian influenza A (H7N9) viruses with bird-to-human transmissibility: potential implication for animal surveillances

artículo científico publicado en 2013

Passive Transfer of A Germline-like Neutralizing Human Monoclonal Antibody Protects Transgenic Mice Against Lethal Middle East Respiratory Syndrome Coronavirus Infection

scientific article published on 19 August 2016

Peptide and non-peptide HIV fusion inhibitors

artículo científico publicado en 2002

Peptide fusion inhibitors targeting the HIV-1 gp41: a patent review (2009 - 2014).

artículo científico publicado en 2014

Peptide-Based Membrane Fusion Inhibitors Targeting HCoV-229E Spike Protein HR1 and HR2 Domains.

artículo científico publicado en 2018

Peptides derived from HIV-1 gp120 co-receptor binding domain form amyloid fibrils and enhance HIV-1 infection

artículo científico publicado en 2014

Peptidic HIV-1 fusion inhibitor VIR576 as a potential dual- functional microbicide inhibits antigen-specific CD4(+) T-cell activation

artículo científico publicado en 2014

Phenotypic and genotypic characterization of human immunodeficiency virus type 1 CRF07_BC strains circulating in the Xinjiang Province of China.

artículo científico publicado en 2009

Phosphorothioate oligonucleotides inhibit human immunodeficiency virus type 1 fusion by blocking gp41 core formation

artículo científico publicado en 2006

Phylogenetic and biological analysis of a laboratory-generated gammaretrovirus xenotropic murine leukemia virus-related virus (XMRV) ⬇️

artículo científico publicado el 27 de junio de 2012

Physicochemical property-driven optimization of diarylaniline compounds as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.

artículo científico publicado en 2014

Polyanionic candidate microbicides accelerate the formation of semen-derived amyloid fibrils to enhance HIV-1 infection

artículo científico publicado en 2013

Polymorphisms of type I interferon receptor 1 promoter and their effects on chronic hepatitis B virus infection

artículo científico publicado en 2006

Potent HIV fusion inhibitors against Enfuvirtide-resistant HIV-1 strains

artículo científico publicado en 2008

Potent and broad neutralizing activity of a single chain antibody fragment against cell-free and cell-associated HIV-1.

artículo científico publicado en 2010

Potent and persistent antibody responses against the receptor-binding domain of SARS-CoV spike protein in recovered patients ⬇️

artículo científico publicado el 4 de noviembre de 2010

Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody

artículo científico publicado en 2020

Potential strategies and biosafety protocols used for dual‐use research on highly pathogenic influenza viruses ⬇️

artículo científico publicado el 14 de septiembre de 2012

Priming with rAAV encoding RBD of SARS-CoV S protein and boosting with RBD-specific peptides for T cell epitopes elevated humoral and cellular immune responses against SARS-CoV infection.

artículo científico publicado en 2008

Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV Infection

artículo científico publicado en 2015

Protocol for Recombinant RBD-based SARS Vaccines: Protein Preparation, Animal Vaccination and Neutralization Detection ⬇️

artículo científico publicado el 2 de mayo de 2011

Pulmonary surfactant-biomimetic nanoparticles potentiate heterosubtypic influenza immunity

artículo científico publicado en 2020

Putative conformations of the receptor-binding domain in S protein of hCoV-EMC in complex with its receptor dipeptidyl peptidase-4.

artículo científico publicado en 2013

Quercetin as an Antiviral Agent Inhibits Influenza A Virus (IAV) Entry

artículo científico publicado en 2015

RBD-Fc-based COVID-19 vaccine candidate induces highly potent SARS-CoV-2 neutralizing antibody response

artículo científico publicado en 2020

Rapid and automated fluorescence-linked immunosorbent assay for high-throughput screening of HIV-1 fusion inhibitors targeting gp41.

artículo científico publicado en 2003

Rational improvement of gp41-targeting HIV-1 fusion inhibitors: an innovatively designed Ile-Asp-Leu tail with alternative conformations.

artículo científico publicado en 2016

Rationally designed anti-HIV peptides containing multifunctional domains as molecule probes for studying the mechanisms of action of the first and second generation HIV fusion inhibitors

artículo científico publicado en 2008

Recent Advances in the Development of Virus-Like Particle-Based Flavivirus Vaccines

scientific article published on 27 August 2020

Recent advances in the detection of respiratory virus infection in humans

article published 15 January 2020

Receptor binding and transmission studies of H5N1 influenza virus in mammals.

artículo científico publicado en 2013

Receptor binding domain based HIV vaccines.

artículo científico publicado en 2015

Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus

artículo científico publicado en 2014

Receptor usage and cell entry of porcine epidemic diarrhea coronavirus

artículo científico publicado en 2015

Receptor-binding domain as a target for developing SARS vaccines.

artículo científico publicado en 2013

Receptor-binding domain of MERS-CoV with optimal immunogen dosage and immunization interval protects human transgenic mice from MERS-CoV infection

artículo científico publicado en 2017

Receptor-binding domain of SARS-CoV spike protein induces highly potent neutralizing antibodies: implication for developing subunit vaccine

artículo científico publicado en 2004

Receptor-binding domain of SARS-CoV spike protein induces long-term protective immunity in an animal model

scientific article published on 30 October 2006

Receptor-binding domain of severe acute respiratory syndrome coronavirus spike protein contains multiple conformation-dependent epitopes that induce highly potent neutralizing antibodies

artículo científico publicado en 2005

Receptor-binding domain-based subunit vaccines against MERS-CoV

artículo científico publicado en 2015

Receptor-binding domain-specific human neutralizing monoclonal antibodies against SARS-CoV and SARS-CoV-2

artículo científico publicado en 2020

Receptor-binding domains of spike proteins of emerging or re-emerging viruses as targets for development of antiviral vaccines.

artículo científico publicado en 2012

Recombinant Ov-ASP-1, a Th1-biased protein adjuvant derived from the helminth Onchocerca volvulus, can directly bind and activate antigen-presenting cells

artículo científico publicado en 2009

Recombinant Receptor-Binding Domains of Multiple Middle East Respiratory Syndrome Coronaviruses (MERS-CoVs) Induce Cross-Neutralizing Antibodies against Divergent Human and Camel MERS-CoVs and Antibody Escape Mutants

scientific article published on 19 October 2016

Recombinant adeno-associated virus expressing the receptor-binding domain of severe acute respiratory syndrome coronavirus S protein elicits neutralizing antibodies: Implication for developing SARS vaccines

artículo científico publicado en 2006

Recombinant receptor-binding domain of SARS-CoV spike protein expressed in mammalian, insect and E. coli cells elicits potent neutralizing antibody and protective immunity

artículo científico publicado en 2009

Research and development of universal influenza vaccines

artículo científico publicado en 2010

Respiratory syncytial virus entry inhibitors targeting the F protein

artículo científico publicado en 2013

Roadmap to developing a recombinant coronavirus S protein receptor-binding domain vaccine for severe acute respiratory syndrome

artículo científico publicado en 2012

Rock1 is a novel host dependency factor of human enterovirus A71: Implication as a drug target

artículo científico publicado en 2022

Role of the fusion peptide and membrane-proximal domain in HIV-1 envelope glycoprotein-mediated membrane fusion

artículo científico publicado en 2003

Roles of the hemagglutinin of influenza A virus in viral entry and development of antiviral therapeutics and vaccines

scientific article published on April 2010

SARS vaccine development

artículo científico publicado en 2005

SEVI and Semen Impair the Anti-HIV-1 Activity of Drugs and Microbicides

article

Safety evaluation of chemically modified beta-lactoglobulin administered intravaginally

artículo científico publicado en 2015

Salmonella typhi Ty21a bacterial ghost vector augments HIV-1 gp140 DNA vaccine-induced peripheral and mucosal antibody responses via TLR4 pathway ⬇️

artículo científico publicado el 20 de julio de 2012

Salvianolic acid C potently inhibits SARS-CoV-2 infection by blocking the formation of six-helix bundle core of spike protein

artículo científico publicado en 2020

Searching for an ideal vaccine candidate among different MERS coronavirus receptor-binding fragments--the importance of immunofocusing in subunit vaccine design

artículo científico publicado en 2014

Selection of a novel gp41-specific HIV-1 neutralizing human antibody by competitive antigen panning

artículo científico publicado en 2006

Semen enhances HIV infectivity and impairs the antiviral efficacy of microbicides

artículo científico publicado en 2014

Serological investigation of subclinical influenza A(H7H9) infection among healthcare and non-healthcare workers in Zhejiang Province, China

artículo científico publicado en 2013

Short cyclic peptides derived from the C-terminal sequence of α1-antitrypsin exhibit significant anti-HIV-1 activity ⬇️

artículo científico publicado el 22 de febrero de 2012

Simultaneous expression of displayed and secreted antibodies for antibody screen

artículo científico publicado en 2013

Single-Domain Antibodies As Therapeutics against Human Viral Diseases

artículo científico publicado en 2017

Site-specific Isopeptide Bridge Tethering of Chimeric gp41 N-terminal Heptad Repeat Helical Trimers for the Treatment of HIV-1 Infection.

artículo científico publicado en 2016

Small molecule fusion inhibitors: design, synthesis and biological evaluation of (Z)-3-(5-(3-benzyl-4-oxo-2-thioxothiazolidinylidene)methyl)-N-(3-carboxy-4-hydroxy)phenyl-2,5-dimethylpyrroles and related derivatives targeting HIV-1 gp41.

artículo científico publicado en 2013

Small-molecule HIV-1 entry inhibitors targeting gp120 and gp41: a patent review (2010-2015).

artículo científico publicado en 2017

Sodium Copper Chlorophyllin Is Highly Effective against Enterovirus (EV) A71 Infection by Blocking Its Entry into the Host Cell

artículo científico publicado en 2020

Structure-based design, synthesis and biological evaluation of new N-carboxyphenylpyrrole derivatives as HIV fusion inhibitors targeting gp41.

artículo científico publicado en 2009

Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor

artículo científico publicado en 2014

Structure-based identification of small molecule compounds targeting cell cyclophilin A with anti-HIV-1 activity

artículo científico publicado en 2007

Studying the nucleated mammalian cell membrane by single molecule approaches

artículo científico publicado en 2014

Surface exposure of the HIV-1 env cytoplasmic tail LLP2 domain during the membrane fusion process: interaction with gp41 fusion core

artículo científico publicado en 2008

Susceptibility of HIV-1 Subtypes B′, CRF07_BC and CRF01_AE that Are Predominantly Circulating in China to HIV-1 Entry Inhibitors ⬇️

artículo científico publicado el 11 de marzo de 2011

Synergistic effect resulting from combinations of a bifunctional HIV-1 antagonist with antiretroviral drugs.

artículo científico publicado en 2014

Synergistic efficacy of combination of enfuvirtide and sifuvirtide, the first- and next-generation HIV-fusion inhibitors

scientific article published on March 2009

Synthesis and anti-HIV-1 activity of 4-[4-(4,6-bisphenylamino-triazin-2-ylamino)-5-methoxy-2-methylphenylazo]-5-hydroxynaphthalene-2,7-disulfonic acid and its derivatives

artículo científico publicado en 2004

The First Disease X is Caused by a Highly Transmissible Acute Respiratory Syndrome Coronavirus

artículo científico publicado en 2020

The HEPT Analogue WPR-6 Is Active against a Broad Spectrum of Nonnucleoside Reverse Transcriptase Drug-Resistant HIV-1 Strains of Different Serotypes

artículo científico publicado en 2015

The adjuvanticity of an O. volvulus-derived rOv-ASP-1 protein in mice using sequential vaccinations and in non-human primates

artículo científico publicado en 2012

The conserved residue Arg46 in the N-terminal heptad repeat domain of HIV-1 gp41 is critical for viral fusion and entry

artículo científico publicado en 2012

The development of HIV vaccines targeting gp41 membrane-proximal external region (MPER): challenges and prospects

artículo científico publicado en 2018

The function of coreceptor as a basis for the kinetic dissection of HIV type 1 envelope protein-mediated cell fusion

artículo científico publicado en 2007

The in vitro and in vivo protective activity of monoclonal antibodies directed against Hantaan virus: potential application for immunotherapy and passive immunization

artículo científico publicado en 2002

The latest advancements in Zika virus vaccine development

artículo científico

The mechanism by which molecules containing the HIV gp41 core-binding motif HXXNPF inhibit HIV-1 envelope glycoprotein-mediated syncytium formation

artículo científico publicado en 2007

The outbreak of avian influenza A (H7N9) in China: current status and future prospects

artículo científico publicado en 2013

The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin

artículo científico publicado en 2020

The spike protein of SARS-CoV--a target for vaccine and therapeutic development

artículo científico publicado en 2009

Theaflavin derivatives in black tea and catechin derivatives in green tea inhibit HIV-1 entry by targeting gp41

artículo científico publicado en 2005

Transfusion-Transmitted Zika Virus Infection in Pregnant Mice Leads to Broad Tissue Tropism With Severe Placental Damage and Fetal Demise

artículo científico publicado en 2019

Treatment of Paraquat-Induced Lung Injury With an Anti-C5a Antibody: Potential Clinical Application

artículo científico publicado en 2018

Tricyclononene carboxamide derivatives as novel anti-HIV-1 agents

artículo científico publicado en 2010

Two Mutations Were Critical for Bat-to-Human Transmission of Middle East Respiratory Syndrome Coronavirus

artículo científico publicado en 2015

Up-regulation of human cervical cancer proto-oncogene contributes to hepatitis B virus-induced malignant transformation of hepatocyte by down-regulating E-cadherin

artículo científico publicado en 2015

Urgent development of effective therapeutic and prophylactic agents to control the emerging threat of Middle East respiratory syndrome (MERS).

artículo científico publicado en 2015

Vaccine design for severe acute respiratory syndrome coronavirus

artículo científico publicado en 2005

Vaccines for the prevention against the threat of MERS-CoV.

artículo científico publicado en 2016

Vaginal gel formulation based on theaflavin derivatives as a microbicide to prevent HIV sexual transmission

artículo científico publicado en 2012

Virtual screening of small molecular HIV-1 entry inhibitor NC-2 targeting gp120 and its action mechanism

artículo científico publicado en 2013

Visual and Motor Deficits in Grown-up Mice with Congenital Zika Virus Infection

artículo científico publicado en 2017

What can academia learn from XMRV studies? ⬇️

artículo científico publicado el 14 de febrero de 2012

XTT formazan widely used to detect cell viability inhibits HIV type 1 infection in vitro by targeting gp41.

artículo científico publicado en 2002

Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate

artículo científico publicado en 2013

[Expression, structure and antigenicity analysis of N51 derived from the N-terminal heptad repeat domain in gp41 of HIV-1 CRF07_BC strain]

artículo científico publicado en 2012

rOv-ASP-1, a recombinant secreted protein of the helminth Onchocercavolvulus, is a potent adjuvant for inducing antibodies to ovalbumin, HIV-1 polypeptide and SARS-CoV peptide antigens

artículo científico publicado en 2005

θ-Defensins Prevent HIV-1 Env-mediated Fusion by Binding gp41 and Blocking 6-Helix Bundle Formation

artículo científico publicado en 2006

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