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A Novel Method for Genetic Transformation of Yeast Cells Using Oligoelectrolyte Polymeric Nanoscale Carriers

artículo científico publicado el 1 de enero de 2013

A laboratory test of evolutionary aging theories

artículo científico publicado en 2017

A mitochondrially targeted compound delays aging in yeast through a mechanism linking mitochondrial membrane lipid metabolism to mitochondrial redox biology

artículo científico publicado en 2014

A network of interorganellar communications underlies cellular aging

artículo científico publicado el 2 de julio de 2013

A new definition for the consensus sequence of the peroxisome targeting signal type 2.

artículo científico publicado en 2004

A novel approach to the discovery of anti-tumor pharmaceuticals: searching for activators of liponecrosis

artículo científico publicado en 2016

A quantitative assessment of the yeast lipidome using electrospray ionization mass spectrometry

artículo científico publicado en 2009

A signal from inside the peroxisome initiates its division by promoting the remodeling of the peroxisomal membrane

artículo científico publicado en 2007

Acyl-CoA oxidase is imported as a heteropentameric, cofactor-containing complex into peroxisomes of Yarrowia lipolytica

artículo científico publicado en 2002

Aging and Age-related Disorders: From Molecular Mechanisms to Therapies

scientific article published on 03 July 2019

Bile acids induce apoptosis selectively in androgen-dependent and -independent prostate cancer cells

artículo científico publicado en 2013

Caloric Restriction Extends Yeast Chronological Lifespan by Altering a Pattern of Age-Related Changes in Trehalose Concentration

artículo científico publicado el 6 de julio de 2012

Caloric restriction extends yeast chronological lifespan via a mechanism linking cellular aging to cell cycle regulation, maintenance of a quiescent state, entry into a non-quiescent state and survival in the non-quiescent state

artículo científico publicado en 2017

Cell-Nonautonomous Mechanisms Underlying Cellular and Organismal Aging

artículo científico publicado en 2015

Cell-autonomous mechanisms of chronological aging in the yeast Saccharomyces cerevisiae

artículo científico publicado en 2014

Cells with impaired mitochondrial H2O2 sensing generate less •OH radicals and live longer

artículo científico publicado en 2014

Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes

artículo científico publicado en 2010

Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processes

artículo científico publicado en 2016

Dynamic ergosterol- and ceramide-rich domains in the peroxisomal membrane serve as an organizing platform for peroxisome fusion

artículo científico publicado en 2005

Effect of calorie restriction on the metabolic history of chronologically aging yeast

artículo científico publicado en 2009

Empirical Validation of a Hypothesis of the Hormetic Selective Forces Driving the Evolution of Longevity Regulation Mechanisms

artículo científico publicado en 2016

Empirical verification of evolutionary theories of aging

scientific article published on 25 October 2016

Essential Roles of Peroxisomally Produced and Metabolized Biomolecules in Regulating Yeast Longevity

artículo científico publicado el 1 de enero de 2013

Guidelines and recommendations on yeast cell death nomenclature.

artículo científico publicado en 2018

Integration of peroxisomes into an endomembrane system that governs cellular aging

artículo científico publicado el 17 de julio de 2012

Interspecies Chemical Signals Released into the Environment may Create Xenohormetic, Hormetic and Cytostatic Selective Forces that Drive the Ecosystemic Evolution of Longevity Regulation Mechanisms

artículo científico publicado el 27 de julio de 2011

Isolation and characterization of peroxisomal protein import (Pim−) mutants ofHansenula polymorpha

artículo científico publicado en 1992

Lithocholic acid extends longevity of chronologically aging yeast only if added at certain critical periods of their lifespan

artículo científico publicado en 2012

Lithocholic acid induces endoplasmic reticulum stress, autophagy and mitochondrial dysfunction in human prostate cancer cells.

artículo científico publicado en 2016

Lithocholic bile acid accumulated in yeast mitochondria orchestrates a development of an anti-aging cellular pattern by causing age-related changes in cellular proteome

artículo científico publicado en 2015

Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells

artículo científico publicado el 1 de octubre de 2011

Longevity extension by phytochemicals

artículo científico publicado en 2015

Macromitophagy is a longevity assurance process that in chronologically aging yeast limited in calorie supply sustains functional mitochondria and maintains cellular lipid homeostasis

artículo científico publicado en 2013

Macromitophagy, neutral lipids synthesis, and peroxisomal fatty acid oxidation protect yeast from "liponecrosis", a previously unknown form of programmed cell death

artículo científico publicado en 2013

Mechanism of liponecrosis, a distinct mode of programmed cell death

artículo científico publicado en 2014

Mechanisms Underlying the Essential Role of Mitochondrial Membrane Lipids in Yeast Chronological Aging

artículo científico publicado en 2017

Mechanisms by which different functional states of mitochondria define yeast longevity

artículo científico

Mechanisms that Link Chronological Aging to Cellular Quiescence in Budding Yeast

artículo científico publicado en 2020

Mechanisms underlying the anti-aging and anti-tumor effects of lithocholic bile acid

artículo científico publicado en 2014

Mitochondria operate as signaling platforms in yeast aging

artículo científico publicado en 2016

Mitochondrial membrane lipidome defines yeast longevity

artículo científico publicado el 1 de julio de 2013

Molecular and Cellular Mechanisms of Aging and Age-related Disorders

artículo científico publicado en 2018

Origin and spatiotemporal dynamics of the peroxisomal endomembrane system

artículo científico publicado en 2014

Overproduction of translation elongation factor 1-alpha (eEF1A) suppresses the peroxisome biogenesis defect in a Hansenula polymorpha pex3 mutant via translational read-through

artículo científico publicado en 2007

Peroxisome division in the yeast Yarrowia lipolytica is regulated by a signal from inside the peroxisome

artículo científico publicado en 2003

Purification of mitochondria from yeast cells

artículo científico publicado en 2009

Quasi-programmed aging of budding yeast: a trade-off between programmed processes of cell proliferation, differentiation, stress response, survival and death defines yeast lifespan

artículo científico

RNA interference of peroxisome-related genes in C. elegans: a new model for human peroxisomal disorders

artículo científico publicado en 2002

Remodeling of lipid bodies by docosahexaenoic acid in activated microglial cells

artículo científico publicado en 2016

Some Metabolites Act as Second Messengers in Yeast Chronological Aging.

artículo científico publicado en 2018

Specific changes in mitochondrial lipidome alter mitochondrial proteome and increase the geroprotective efficiency of lithocholic acid in chronologically aging yeast

artículo científico publicado en 2017

The Intricate Interplay between Mechanisms Underlying Aging and Cancer

artículo científico

The peroxisome: orchestrating important developmental decisions from inside the cell

artículo científico publicado en 2004

The spatiotemporal dynamics of longevity-defining cellular processes and its modulation by genetic, dietary, and pharmacological anti-aging interventions.

artículo científico publicado en 2012

Very-long-chain fatty acid metabolic capacity of 17-beta-hydroxysteroid dehydrogenase type 12 (HSD17B12) promotes replication of hepatitis C virus and related flaviviruses

artículo científico publicado en 2020

Xenohormetic, hormetic and cytostatic selective forces driving longevity at the ecosystemic level

artículo científico publicado el 1 de agosto de 2010

Yeast Cells Exposed to Exogenous Palmitoleic Acid Either Adapt to Stress and Survive or Commit to Regulated Liponecrosis and Die.

artículo científico publicado en 2018