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A Novel Functional Polymer with Tunable LCST

A Polymer Therapeutic Having Universal Heparin Reversal Activity: Molecular Design and Functional Mechanism.

artículo científico publicado en 2017

A nanoparticle-preparation kit using ethylene glycol-based block copolymers with a common temperature-responsive block

A pH and thermosensitive choline phosphate-based delivery platform targeted to the acidic tumor microenvironment

artículo científico publicado en 2013

A planar model of the vessel wall from cellularized-collagen scaffolds: focus on cell-matrix interactions in mono-, bi- and tri-culture models

artículo científico publicado en 2016

A thermoreversible poly(choline phosphate) based universal biomembrane adhesive.

artículo científico publicado en 2013

ATRP synthesis of poly(2-(methacryloyloxy)ethyl choline phosphate): a multivalent universal biomembrane adhesive.

artículo científico publicado en 2013

Abnormal blood clot formation induced by temperature responsive polymers by altered fibrin polymerization and platelet binding

artículo científico publicado en 2013

Advantages of replacing hydroxyethyl starch in University of Wisconsin solution with hyperbranched polyglycerol for cold kidney perfusion.

artículo científico publicado en 2016

Affinity-based design of a synthetic universal reversal agent for heparin anticoagulants.

artículo científico publicado en 2014

Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA.

artículo científico publicado en 2016

An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient

artículo científico publicado en 2019

An enzymatic pathway in the human gut microbiome that converts A to universal O type blood

scientific article published on 10 June 2019

An investigation of vibration-induced protein desorption mechanism using a micromachined membrane and PZT plate

artículo científico publicado en 2008

Anti-adhesive antimicrobial peptide coating prevents catheter associated infection in a mouse urinary infection model

artículo científico publicado en 2016

Antibacterial Surfaces Based on Polymer Brushes: Investigation on the Influence of Brush Properties on Antimicrobial Peptide Immobilization and Antimicrobial Activity

article

Antibacterial properties of hLf1-11 peptide onto titanium surfaces: a comparison study between silanization and surface initiated polymerization

artículo científico publicado en 2015

Antigens protected functional red blood cells by the membrane grafting of compact hyperbranched polyglycerols

artículo científico publicado en 2013

Antimicrobial Peptide-Polymer Conjugates with High Activity: Influence of Polymer Molecular Weight and Peptide Sequence on Antimicrobial Activity, Proteolysis, and Biocompatibility

artículo científico publicado en 2017

Antimicrobial Peptides: Diversity, Mechanism of Action and Strategies to Improve the Activity and Biocompatibility In Vivo

artículo científico publicado en 2018

Approaches to prevent bleeding associated with anticoagulants: current status and recent developments

artículo científico publicado en 2017

Attractive bridging interactions in dense polymer brushes in good solvent measured by atomic force microscopy.

artículo científico publicado en 2004

Aurein-Derived Antimicrobial Peptides Formulated with Pegylated Phospholipid Micelles to Target Methicillin-Resistant Staphylococcus aureus Skin Infections

scientific article published on 02 January 2019

Barrier Capacity of Hydrophilic Polymer Brushes To Prevent Hydrophobic Interactions: Effect of Graft Density and Hydrophilicity

Bending and stretching actuation of soft materials through surface-initiated polymerization

artículo científico publicado en 2011

Biodegradable polyglycerols with randomly distributed ketal groups as multi-functional drug delivery systems.

artículo científico publicado en 2013

Biomembrane Interactions Reveal the Mechanism of Action of Surface-Immobilized Host Defense IDR-1010 Peptide

article

Blood Components Interactions to Ionic and Nonionic Glyconanogels.

artículo científico publicado en 2015

Blood circulation of soft nanomaterials is governed by dynamic remodeling of protein opsonins at nano-biointerface

artículo científico publicado en 2020

Blood compatibility of novel water soluble hyperbranched polyglycerol-based multivalent cationic polymers and their interaction with DNA

scientific article published on 18 July 2006

Branched multifunctional polyether polyketals: variation of ketal group structure enables unprecedented control over polymer degradation in solution and within cells

artículo científico publicado en 2012

Carbohydrate structure dependent hemocompatibility of biomimetic functional polymer brushes on surfaces

artículo científico publicado en 2012

Chain Length and Grafting Density Dependent Enhancement in the Hydrolysis of Ester-Linked Polymer Brushes.

artículo científico publicado en 2015

Choline phosphate functionalized cellulose membrane: A potential hemostatic dressing based on a unique bioadhesion mechanism

artículo científico publicado en 2016

Chronic periodontitis is associated with platelet factor 4 (PF4) secretion: A pilot study

artículo científico publicado en 2017

Clinically approved iron chelators influence zebrafish mortality, hatching morphology and cardiac function

artículo científico publicado en 2014

Cold preservation with hyperbranched polyglycerol-based solution improves kidney functional recovery with less injury at reperfusion in rats

artículo científico publicado en 2017

Comparative Degradomics of Porcine and Human Wound Exudates Unravels Biomarker Candidates for Assessment of Wound Healing Progression in Trauma Patients

artículo científico publicado en 2017

Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors

Complexes of poly(ethylene glycol)-based cationic random copolymer and calf thymus DNA: a complete biophysical characterization

artículo científico publicado en 2004

Conjugation of aurein 2.2 to HPG yields an antimicrobial with better properties.

artículo científico publicado en 2015

Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts ⬇️

artículo científico publicado el 1 de noviembre de 2011

Deep Profiling of the Cleavage Specificity and Human Substrates of Snake Venom Metalloprotease HF3 by Proteomic Identification of Cleavage Site Specificity (PICS) Using Proteome Derived Peptide Libraries and Terminal Amine Isotopic Labeling of Subst

artículo científico publicado en 2019

Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome.

artículo científico publicado en 2012

Design Considerations for Developing Hyperbranched Polyglycerol Nanoparticles as Systemic Drug Carriers.

artículo científico publicado en 2016

Design of Polyphosphate Inhibitors: A Molecular Dynamics Investigation on Polyethylene Glycol-Linked Cationic Binding Groups.

artículo científico publicado en 2018

Design of Safe Nanotherapeutics for the Excretion of Excess Systemic Toxic Iron

article

Design of long circulating nontoxic dendritic polymers for the removal of iron in vivo

artículo científico publicado en 2013

Development of Antifouling and Bactericidal Coatings for Platelet Storage Bags Using Dopamine Chemistry

artículo científico publicado en 2017

Development of soluble ester-linked aldehyde polymers for proteomics.

artículo científico publicado en 2011

Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis.

artículo científico publicado en 2013

Durable Surfaces from Film-Forming Silver Assemblies for Long-Term Zero Bacterial Adhesion without Toxicity

artículo científico publicado en 2022

Effect of Extreme Wettability on Platelet Adhesion on Metallic Implants: From Superhydrophilicity to Superhydrophobicity

artículo científico publicado en 2016

Electric field and vibration-assisted nanomolecule desorption and anti-biofouling for biosensor applications

artículo científico publicado en 2007

Engineering biomaterials surfaces to modulate the host response

artículo científico

Enhanced cell surface polymer grafting in concentrated and nonreactive aqueous polymer solutions.

artículo científico publicado en 2010

Enhancement of biological reactions on cell surfaces via macromolecular crowding

artículo científico publicado en 2014

Evaluation of an atomic force microscopy pull-off method for measuring molecular weight and polydispersity of polymer brushes: effect of grafting density.

artículo científico publicado en 2004

Evaluation of hyperbranched polyglycerol for cold perfusion and storage of donor kidneys in a pig model of kidney autotransplantation

artículo científico publicado en 2020

Formalin-Fixed, Paraffin-Embedded Tissues (FFPE) as a Robust Source for the Profiling of Native and Protease-Generated Protein Amino Termini.

artículo científico

Global Profiling of Proteolysis from the Mitochondrial Amino Terminome during Early Intrinsic Apoptosis Prior to Caspase-3 Activation

scientific article published on 29 October 2018

Hemocompatibility of Degrading Polymeric Biomaterials: Degradable Polar Hydrophobic Ionic Polyurethane versus Poly(lactic-co-glycolic) Acid

artículo científico publicado en 2017

Hemocompatibility studies on a degradable polar hydrophobic ionic polyurethane (D-PHI).

artículo científico publicado en 2016

High molecular weight polyglycerol-based multivalent mannose conjugates.

artículo científico publicado en 2010

Hybrid polyglycerols with long blood circulation: synthesis, biocompatibility, and biodistribution

artículo científico publicado en 2014

Hydrophobically derivatized hyperbranched polyglycerol as a human serum albumin substitute

artículo científico publicado en 2008

Hyperbranched glycopolymers for blood biocompatibility

artículo científico publicado en 2012

Hyperbranched polyglycerol as a colloid in cold organ preservation solutions

artículo científico publicado en 2015

Hyperbranched polyglycerol is an efficacious and biocompatible novel osmotic agent in a rodent model of peritoneal dialysis

artículo científico publicado en 2013

Hyperbranched polyglycerol is superior to glucose for long-term preservation of peritoneal membrane in a rat model of chronic peritoneal dialysis.

artículo científico publicado en 2016

Hyperbranched polyglycerols: recent advances in synthesis, biocompatibility and biomedical applications

scientific article published on 07 November 2017

Identification of proteolytic products and natural protein N-termini by Terminal Amine Isotopic Labeling of Substrates (TAILS)

scientific article published on 01 January 2011

Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates

artículo científico publicado en 2011

In Vivo Biological Evaluation of High Molecular Weight Multifunctional Acid-Degradable Polymeric Drug Carriers with Structurally Different Ketals

artículo científico publicado en 2016

In vitro chelating, cytotoxicity, and blood compatibility of degradable poly(ethylene glycol)-based macromolecular iron chelators

artículo científico publicado en 2008

In vivo assessment of protease dynamics in cutaneous wound healing by degradomics analysis of porcine wound exudates

artículo científico publicado en 2014

Influence of architecture of high molecular weight linear and branched polyglycerols on their biocompatibility and biodistribution

artículo científico publicado en 2012

Influence of dynamic flow conditions on adsorbed plasma protein corona and surface-induced thrombus generation on antifouling brushes

artículo científico publicado en 2018

Influence of polymer architecture on antigens camouflage, CD47 protection and complement mediated lysis of surface grafted red blood cells.

artículo científico publicado en 2012

Inhibitory effect of hydrophilic polymer brushes on surface-induced platelet activation and adhesion

artículo científico publicado en 2010

Interaction of blood components with cathelicidins and their modified versions.

artículo científico publicado en 2015

Intravenously injected human apolipoprotein A-I rapidly enters the central nervous system via the choroid plexus

artículo científico publicado en 2014

Investigation of hydrophobically derivatized hyperbranched polyglycerol with PEGylated shell as a nanocarrier for systemic delivery of chemotherapeutics.

artículo científico publicado en 2015

In vivo circulation, clearance, and biodistribution of polyglycerol grafted functional red blood cells

artículo científico publicado en 2012

In vivo efficacy, toxicity and biodistribution of ultra-long circulating desferrioxamine based polymeric iron chelator.

artículo científico publicado en 2016

Iron Binding and Iron Removal Efficiency of Desferrioxamine Based Polymeric Iron Chelators: Influence of Molecular Size and Chelator Density

artículo científico publicado en 2016

Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products

artículo científico publicado en 2010

Laser-Light-Scattering Study of Internal Motions of Polymer Chains Grafted on Spherical Latex Particles

article by Cheng Yang et al published December 2004 in Journal of Physical Chemistry

Lectin interactions on surface-grafted glycostructures: influence of the spatial distribution of carbohydrates on the binding kinetics and rupture forces

artículo científico publicado en 2013

Linear and hyperbranched phosphorylcholine based homopolymers for blood biocompatibility

MANTI: Automated Annotation of Protein N-Termini for Rapid Interpretation of N-Terminome Data Sets

artículo científico publicado en 2021

Master Sculptor at Work: Enteropathogenic Escherichia coli Infection Uniquely Modifies Mitochondrial Proteolysis during Its Control of Human Cell Death

scientific article published on 02 June 2020

Matrix Metalloproteinase 10 Degradomics in Keratinocytes and Epidermal Tissue Identifies Bioactive Substrates With Pleiotropic Functions

artículo científico publicado en 2015

Mega macromolecules as single molecule lubricants for hard and soft surfaces

artículo científico publicado en 2020

Modulation of Multivalent Protein Binding on Surfaces by Glycopolymer Brush Chemistry

artículo científico publicado en 2016

Modulation of complement activation and amplification on nanoparticle surfaces by glycopolymer conformation and chemistry

artículo científico publicado en 2014

Molecular Dynamics Simulations on Nucleic Acid Binding Polymers Designed To Arrest Thrombosis

scientific article published on 20 August 2018

Molecular weight and polydispersity estimation of adsorbing polymer brushes by atomic force microscopy.

artículo científico publicado en 2004

Monitoring matrix metalloproteinase activity at the epidermal-dermal interface by SILAC-iTRAQ-TAILS.

artículo científico

Mucin-Inspired, High Molecular Weight Virus Binding Inhibitors Show Biphasic Binding Behavior to Influenza A Viruses

scientific article published on 01 November 2020

Multilayered coating on titanium for controlled release of antimicrobial peptides for the prevention of implant-associated infections

artículo científico publicado en 2013

N-Degradomic Analysis Reveals a Proteolytic Network Processing the Podocyte Cytoskeleton.

artículo científico publicado en 2017

N-Terminomics TAILS identifies host cell substrates of poliovirus and coxsackievirus B3 3C proteinases that modulate virus infection.

artículo científico publicado en 2018

N-Terminomics/TAILS Profiling of Proteases and Their Substrates in Ulcerative Colitis

scientific article published on 21 August 2019

Nonbiofouling polymer brush with latent aldehyde functionality as a template for protein micropatterning

artículo científico publicado en 2010

Nontoxic polyphosphate inhibitors reduce thrombosis while sparing hemostasis.

artículo científico publicado en 2014

Nontransformed and Cancer Cells Can Utilize Different Endocytic Pathways To Internalize Dendritic Nanoparticle Variants: Implications on Nanocarrier Design

artículo científico publicado en 2017

Oncotically Driven Control over Glycocalyx Dimension for Cell Surface Engineering and Protein Binding in the Longitudinal Direction.

artículo científico publicado en 2018

Peritoneal and Systemic Responses of Obese Type II Diabetic Rats to Chronic Exposure to a Hyperbranched Polyglycerol-Based Dialysis Solution

artículo científico publicado en 2018

Plasma protein adsorption to surfaces grafted with dense homopolymer and copolymer brushes containing poly(N-isopropylacrylamide)

scientific article published on 01 January 2004

Poly(oligo(ethylene glycol)acrylamide) brushes by surface initiated polymerization: effect of macromonomer chain length on brush growth and protein adsorption from blood plasma.

artículo científico publicado en 2009

Polyglycerol based Macromolecular Iron Chelator Adjuvants for Antibiotics to Treat Drug Resistant Bacteria

artículo científico publicado en 2020

Polymer brush-based approaches for the development of infection-resistant surfaces

artículo científico publicado en 2014

Polymer-Nanoparticle Interaction as a Design Principle in the Development of a Durable Ultra-Thin Universal Binary Anti-Biofilm Coating with Long-Term Activity

artículo científico publicado en 2018

Polymeric nanocarriers for the treatment of systemic iron overload

artículo científico publicado en 2015

Polyvalent choline phosphate as a universal biomembrane adhesive.

artículo científico publicado en 2012

Profiling of Protein N-Termini and Their Modifications in Complex Samples.

artículo científico publicado en 2017

Proteomic and N-Terminomic TAILS Analyses of Human Alveolar Bone Proteins: Improved Protein Extraction Methodology and LysargiNase Digestion Strategies Increase Proteome Coverage and Missing Protein Identification

artículo científico publicado en 2019

Rationalized approach to the determination of contact point in force-distance curves: application to polymer brushes in salt solutions and in water

artículo científico publicado en 2010

Red blood cell membrane grafting of multi-functional hyperbranched polyglycerols

artículo científico publicado en 2010

Reversible hemostatic properties of sulfabetaine/quaternary ammonium modified hyperbranched polyglycerol

artículo científico publicado en 2016

Secretome and degradome profiling shows that Kallikrein-related peptidases 4, 5, 6, and 7 induce TGFβ-1 signaling in ovarian cancer cells

artículo científico publicado en 2013

Self-assembled monothiol-terminated hyperbranched polyglycerols on a gold surface: a comparative study on the structure, morphology, and protein adsorption characteristics with linear poly(ethylene glycol)s

artículo científico publicado en 2008

Simplified high yield TAILS terminomics using a new HPG-ALD 800K-2000 polymer with precipitation

scientific article published on 13 August 2019

Skin Barrier Defects Caused by Keratinocyte-Specific Deletion of ADAM17 or EGFR Are Based on Highly Similar Proteome and Degradome Alterations.

artículo científico publicado en 2016

Stimuli-responsive cationic terpolymers by RAFT polymerization: Synthesis, characterization, and protein interaction studies

Surface Modification of Polyvinyl Chloride Sheets via Growth of Hydrophilic Polymer Brushes

Surface modification approaches for prevention of implant associated infections

scientific article published on 12 May 2020

Synthesis and characterization of carboxylic acid conjugated, hydrophobically derivatized, hyperbranched polyglycerols as nanoparticulate drug carriers for cisplatin

artículo científico publicado en 2010

Synthesis and characterization of well-defined hydrophilic block copolymer brushes by aqueous ATRP

article

Synthesis of Functional Polymer Brushes Containing Carbohydrate Residues in the Pyranose Form and Their Specific and Nonspecific Interactions with Proteins ⬇️

artículo científico publicado el 18 de octubre de 2010

Synthesis of Thermoresponsive Mixed Arm Star Polymers by Combination of RAFT and ATRP from a Multifunctional Core and Its Self-Assembly in Water

Synthesis of Well-Defined Environmentally Responsive Polymer Brushes by Aqueous ATRP

Synthesis of novel size exclusion chromatography support by surface initiated aqueous atom transfer radical polymerization.

artículo científico publicado en 2007

Synthesis, characterization, and biocompatibility of biodegradable hyperbranched polyglycerols from acid-cleavable ketal group functionalized initiators

artículo científico publicado en 2012

Targeting Biological Polyanions in Blood: Strategies towards the Design of Therapeutics

artículo científico publicado en 2020

The biocompatibility and biofilm resistance of implant coatings based on hydrophilic polymer brushes conjugated with antimicrobial peptides

artículo científico publicado en 2011

The induction of thrombus generation on nanostructured neutral polymer brush surfaces

artículo científico publicado en 2010

The influence of grafted polymer architecture and fluid hydrodynamics on protein separation by entropic interaction chromatography

artículo científico publicado en 2007

The influence of poly-N-[(2,2-dimethyl-1,3-dioxolane)methyl]acrylamide on fibrin polymerization, cross-linking and clot structure

artículo científico publicado en 2010

The mechanism and modulation of complement activation on polymer grafted cells

artículo científico publicado en 2015

The mouse heart mitochondria N terminome provides insights into ClpXP-mediated proteolysis

artículo científico publicado en 2020

The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury

scientific article published on 03 December 2018

The size-dependent efficacy and biocompatibility of hyperbranched polyglycerol in peritoneal dialysis

artículo científico publicado en 2013

Therapeutic cells via functional modification: influence of molecular properties of polymer grafts on in vivo circulation, clearance, immunogenicity, and antigen protection.

artículo científico publicado en 2013

Thermal reversal of polyvalent choline phosphate, a multivalent universal biomembrane adhesive.

artículo científico publicado en 2013

Time-resolved analysis of the matrix metalloproteinase 10 substrate degradome.

artículo científico publicado en 2013

Toward Efficient Enzymes for the Generation of Universal Blood through Structure-Guided Directed Evolution

artículo científico publicado en 2015

Toward Infection-Resistant Surfaces: Achieving High Antimicrobial Peptide Potency by Modulating the Functionality of Polymer Brush and Peptide

artículo científico publicado en 2015

Towards Robust Delivery of Antimicrobial Peptides to Combat Bacterial Resistance

artículo científico publicado en 2020

Transcriptome analysis of signaling pathways of human peritoneal mesothelial cells in response to different osmotic agents in a peritoneal dialysis solution

artículo científico publicado en 2019

Understanding the interaction of polyelectrolyte architectures with proteins and biosystems

scientific article published on 26 June 2020

Use of Molecular Dynamics for the Refinement of an Electrostatic Model for the In Silico Design of a Polymer Antidote for the Anticoagulant Fondaparinux.

artículo científico publicado en 2013

Water soluble nanoparticles from PEG-based cationic hyperbranched polymer and RNA that protect RNA from enzymatic degradation

artículo científico publicado en 2006

Water-soluble complexes from random copolymer and oppositely charged surfactant. 2. Complexes of poly(ethylene glycol)-based cationic random copolymer and bile salts

artículo científico publicado en 2004

Water-soluble nanoparticles from random copolymer and oppositely charged surfactant, 3a. Nanoparticles of poly(ethylene glycol)-based cationic random copolymer and fatty acid salts

artículo científico publicado en 2005

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