Lista de obras -

1H, 13C, and 15N resonance assignment of the ubiquitin-like domain from Dsk2p

artículo científico publicado en 2008

A hierarchical algorithm for fast debye summation with applications to small angle scattering ⬇️

artículo científico publicado el 18 de junio de 2012

Affinity Makes the Difference: Nonselective Interaction of the UBA Domain of Ubiquilin-1 with Monomeric Ubiquitin and Polyubiquitin Chains

artículo científico publicado en 2008

Allosteric KRas4B Can Modulate SOS1 Fast and Slow Ras Activation Cycles

artículo científico publicado en 2018

An efficient computational method for predicting rotational diffusion tensors of globular proteins using an ellipsoid representation

artículo científico publicado en 2006

Analyses of the effects of all ubiquitin point mutants on yeast growth rate

artículo científico publicado en 2013

Analysis of interdomain dynamics in a two-domain protein using residual dipolar couplings together with 15N relaxation data

artículo científico publicado en 2006

Atom-by-atom analysis of global downhill protein folding

artículo científico publicado en 2006

Autoinhibition in Ras effectors Raf, PI3Kα, and RASSF5: a comprehensive review underscoring the challenges in pharmacological intervention

artículo científico publicado en 2018

Base-CP proteasome can serve as a platform for stepwise lid formation

artículo científico publicado en 2015

Changing the topology of protein backbone: the effect of backbone cyclization on the structure and dynamics of a SH3 domain

artículo científico publicado en 2015

Characterization of the overall and local dynamics of a protein with intermediate rotational anisotropy: Differentiating between conformational exchange and anisotropic diffusion in the B3 domain of protein G.

artículo científico publicado en 2003

Condensed E. coli cultures for highly efficient production of proteins containing unnatural amino acids

artículo científico publicado en 2010

Controlled enzymatic synthesis of natural-linkage, defined-length polyubiquitin chains using lysines with removable protecting groups

artículo científico publicado en 2011

Crystal structure and solution NMR studies of Lys48-linked tetraubiquitin at neutral pH

artículo científico publicado en 2007

Density functional calculations of 15N chemical shifts in solvated dipeptides.

artículo científico publicado en 2008

Deriving quantitative dynamics information for proteins and RNAs using ROTDIF with a graphical user interface.

artículo científico publicado en 2013

Determining Protein Dynamics from 15N Relaxation Data by Using DYNAMICS ⬇️

artículo científico publicado el 1 de enero de 2012

Disassembly of Lys11 and mixed linkage polyubiquitin conjugates provides insights into function of proteasomal deubiquitinases Rpn11 and Ubp6.

artículo científico publicado en 2015

Efficient and accurate determination of the overall rotational diffusion tensor of a molecule from (15)N relaxation data using computer program ROTDIF.

artículo científico publicado en 2004

Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1

artículo científico publicado en 2009

Evidence for cooperative and domain-specific binding of the signal transducing adaptor molecule 2 (STAM2) to Lys63-linked diubiquitin

artículo científico publicado en 2012

Extended ubiquitin species are protein-based DUB inhibitors

artículo científico publicado en 2014

High relaxivity supramolecular adducts between human-liver fatty-acid-binding protein and amphiphilic Gd(III) complexes: structural basis for the design of intracellular targeting MRI probes

artículo científico publicado en 2012

High-Affinity Interactions of the nSH3/cSH3 Domains of Grb2 with the C-Terminal Proline-Rich Domain of SOS1

artículo científico publicado en 2020

Hydrophobic Patch of Ubiquitin is Important for its Optimal Activation by Ubiquitin Activating Enzyme E1.

artículo científico publicado en 2017

Identification of primary and secondary UBA footprints on the surface of ubiquitin in cell-mimicking crowded solution

artículo científico publicado en 2017

Information content of long-range NMR data for the characterization of conformational heterogeneity.

artículo científico publicado en 2015

Intrinsic protein disorder in oncogenic KRAS signaling

artículo científico publicado en 2017

Linkage via K27 Bestows Ubiquitin Chains with Unique Properties among Polyubiquitins.

artículo científico publicado en 2016

Linkage-specific conformational ensembles of non-canonical polyubiquitin chains

artículo científico publicado en 2015

Long‐Lived States to Monitor Protein Unfolding by Proton NMR ⬇️

artículo científico publicado el 31 de agosto de 2011

Measurement of 15N relaxation in deuterated amide groups in proteins using direct nitrogen detection

artículo científico publicado en 2006

Mechanism of Catalysis by l-Asparaginase

artículo científico publicado en 2020

Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation

artículo científico publicado en 2023

Mutations in the Hydrophobic Core of Ubiquitin Differentially Affect Its Recognition by Receptor Proteins

artículo científico publicado en 2008

Nonenzymatic Assembly of Natural Polyubiquitin Chains of Any Linkage Composition and Isotopic Labeling Scheme ⬇️

artículo científico publicado el 19 de octubre de 2011

Perturbing the Ubiquitin Pathway Reveals How Mitosis Is Hijacked to Denucleate and Regulate Cell Proliferation and Differentiation In Vivo ⬇️

artículo científico publicado el 20 de octubre de 2010

Polyhydroxylated [60]fullerene binds specifically to functional recognition sites on a monomeric and a dimeric ubiquitin

artículo científico publicado en 2015

Polyubiquitin chains: polymeric protein signals

artículo científico publicado en 2004

Preparing to read the ubiquitin code: a middle-out strategy for characterization of all lysine-linked diubiquitins.

artículo científico publicado en 2014

Preparing to read the ubiquitin code: characterization of ubiquitin trimers by top-down mass spectrometry

artículo científico publicado en 2016

Probing the Binding Modes of a Multidomain Protein to Lipid-based Nanoparticles by Relaxation-based NMR.

artículo científico publicado en 2017

Proteomic identification and analysis of K63-linked ubiquitin conjugates

artículo científico publicado en 2012

RASSF5: An MST activator and tumor suppressor in vivo but opposite in vitro

artículo científico publicado en 2016

Recognition and cleavage of related to ubiquitin 1 (Rub1) and Rub1-ubiquitin chains by components of the ubiquitin-proteasome system

artículo científico publicado en 2012

Recovering a representative conformational ensemble from underdetermined macromolecular structural data

artículo científico publicado en 2013

Reversible Post-Translational Carboxylation Modulates the Enzymatic Activity of N -Acetyl- l -ornithine Transcarbamylase

artículo científico publicado en 2010

Rpn1 and Rpn2 coordinate ubiquitin processing factors at proteasome

artículo científico publicado en 2012

SOS1 interacts with Grb2 through regions that induce closed nSH3 conformations

artículo científico publicado en 2020

Segmental Isotopic Labeling of Ubiquitin Chains To Unravel Monomer‐Specific Molecular Behavior ⬇️

artículo científico publicado el 28 de septiembre de 2011

Structural Assembly of Multidomain Proteins and Protein Complexes Guided by the Overall Rotational Diffusion Tensor

artículo científico publicado en 2007

Structural and biochemical studies of the open state of Lys48-linked diubiquitin ⬇️

artículo científico publicado el 16 de abril de 2012

Structural assembly of molecular complexes based on residual dipolar couplings

artículo científico publicado en 2010

Structure of the S5a:K48-Linked Diubiquitin Complex and Its Interactions with Rpn13

artículo científico publicado en 2009

The dynamic mechanism of RASSF5 and MST kinase activation by Ras.

artículo científico publicado en 2017

Top-Down Analysis of Branched Proteins Using Mass Spectrometry.

artículo científico publicado en 2018

Top-down Analysis of Novel Synthetic Branched Proteins

artículo científico publicado en 2019

Ubiquitin Chains Bearing Genetically Encoded Photo-Cross-Linkers Enable Efficient Covalent Capture of (Poly)ubiquitin-Binding Domains

scientific article published on 01 February 2019

Unexpected trypsin cleavage at ubiquitinated lysines.

artículo científico publicado en 2015

Unique Structural, Dynamical, and Functional Properties of K11-Linked Polyubiquitin Chains

artículo científico publicado en 2013

Various strategies of using residual dipolar couplings in NMR-driven protein docking: application to Lys48-linked di-ubiquitin and validation against 15N-relaxation data

artículo científico publicado en 2005

Lista de obras de

1H, 13C, and 15N resonance assignment of the ubiquitin-like domain from Dsk2p

A hierarchical algorithm for fast debye summation with applications to small angle scattering ⬇️

Affinity Makes the Difference: Nonselective Interaction of the UBA Domain of Ubiquilin-1 with Monomeric Ubiquitin and Polyubiquitin Chains

Allosteric KRas4B Can Modulate SOS1 Fast and Slow Ras Activation Cycles

An efficient computational method for predicting rotational diffusion tensors of globular proteins using an ellipsoid representation

Analyses of the effects of all ubiquitin point mutants on yeast growth rate

Analysis of interdomain dynamics in a two-domain protein using residual dipolar couplings together with 15N relaxation data

Atom-by-atom analysis of global downhill protein folding

Autoinhibition in Ras effectors Raf, PI3Kα, and RASSF5: a comprehensive review underscoring the challenges in pharmacological intervention

Base-CP proteasome can serve as a platform for stepwise lid formation

Changing the topology of protein backbone: the effect of backbone cyclization on the structure and dynamics of a SH3 domain

Characterization of the overall and local dynamics of a protein with intermediate rotational anisotropy: Differentiating between conformational exchange and anisotropic diffusion in the B3 domain of protein G.

Condensed E. coli cultures for highly efficient production of proteins containing unnatural amino acids

Controlled enzymatic synthesis of natural-linkage, defined-length polyubiquitin chains using lysines with removable protecting groups

Crystal structure and solution NMR studies of Lys48-linked tetraubiquitin at neutral pH

Density functional calculations of 15N chemical shifts in solvated dipeptides.

Deriving quantitative dynamics information for proteins and RNAs using ROTDIF with a graphical user interface.

Determining Protein Dynamics from 15N Relaxation Data by Using DYNAMICS ⬇️

Disassembly of Lys11 and mixed linkage polyubiquitin conjugates provides insights into function of proteasomal deubiquitinases Rpn11 and Ubp6.

Efficient and accurate determination of the overall rotational diffusion tensor of a molecule from (15)N relaxation data using computer program ROTDIF.

Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1

Evidence for cooperative and domain-specific binding of the signal transducing adaptor molecule 2 (STAM2) to Lys63-linked diubiquitin

Extended ubiquitin species are protein-based DUB inhibitors

High relaxivity supramolecular adducts between human-liver fatty-acid-binding protein and amphiphilic Gd(III) complexes: structural basis for the design of intracellular targeting MRI probes

High-Affinity Interactions of the nSH3/cSH3 Domains of Grb2 with the C-Terminal Proline-Rich Domain of SOS1

Hydrophobic Patch of Ubiquitin is Important for its Optimal Activation by Ubiquitin Activating Enzyme E1.

Identification of primary and secondary UBA footprints on the surface of ubiquitin in cell-mimicking crowded solution

Information content of long-range NMR data for the characterization of conformational heterogeneity.

Intrinsic protein disorder in oncogenic KRAS signaling

Linkage via K27 Bestows Ubiquitin Chains with Unique Properties among Polyubiquitins.

Linkage-specific conformational ensembles of non-canonical polyubiquitin chains

Long‐Lived States to Monitor Protein Unfolding by Proton NMR ⬇️

Measurement of 15N relaxation in deuterated amide groups in proteins using direct nitrogen detection

Mechanism of Catalysis by l-Asparaginase

Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation

Mutations in the Hydrophobic Core of Ubiquitin Differentially Affect Its Recognition by Receptor Proteins

Nonenzymatic Assembly of Natural Polyubiquitin Chains of Any Linkage Composition and Isotopic Labeling Scheme ⬇️

Perturbing the Ubiquitin Pathway Reveals How Mitosis Is Hijacked to Denucleate and Regulate Cell Proliferation and Differentiation In Vivo ⬇️

Polyhydroxylated [60]fullerene binds specifically to functional recognition sites on a monomeric and a dimeric ubiquitin

Polyubiquitin chains: polymeric protein signals

Preparing to read the ubiquitin code: a middle-out strategy for characterization of all lysine-linked diubiquitins.

Preparing to read the ubiquitin code: characterization of ubiquitin trimers by top-down mass spectrometry

Probing the Binding Modes of a Multidomain Protein to Lipid-based Nanoparticles by Relaxation-based NMR.

Proteomic identification and analysis of K63-linked ubiquitin conjugates

RASSF5: An MST activator and tumor suppressor in vivo but opposite in vitro

Recognition and cleavage of related to ubiquitin 1 (Rub1) and Rub1-ubiquitin chains by components of the ubiquitin-proteasome system

Recovering a representative conformational ensemble from underdetermined macromolecular structural data

Reversible Post-Translational Carboxylation Modulates the Enzymatic Activity of N -Acetyl- l -ornithine Transcarbamylase

Rpn1 and Rpn2 coordinate ubiquitin processing factors at proteasome

SOS1 interacts with Grb2 through regions that induce closed nSH3 conformations

Segmental Isotopic Labeling of Ubiquitin Chains To Unravel Monomer‐Specific Molecular Behavior ⬇️

Structural Assembly of Multidomain Proteins and Protein Complexes Guided by the Overall Rotational Diffusion Tensor

Structural and biochemical studies of the open state of Lys48-linked diubiquitin ⬇️

Structural assembly of molecular complexes based on residual dipolar couplings

Structure of the S5a:K48-Linked Diubiquitin Complex and Its Interactions with Rpn13

The dynamic mechanism of RASSF5 and MST kinase activation by Ras.

Top-Down Analysis of Branched Proteins Using Mass Spectrometry.

Top-down Analysis of Novel Synthetic Branched Proteins

Ubiquitin Chains Bearing Genetically Encoded Photo-Cross-Linkers Enable Efficient Covalent Capture of (Poly)ubiquitin-Binding Domains

Unexpected trypsin cleavage at ubiquitinated lysines.

Unique Structural, Dynamical, and Functional Properties of K11-Linked Polyubiquitin Chains

Various strategies of using residual dipolar couplings in NMR-driven protein docking: application to Lys48-linked di-ubiquitin and validation against 15N-relaxation data