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A behavior-based drug screening system using a Caenorhabditis elegans model of motor neuron disease

scientific article published on 12 July 2019

A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo

scientific article published on 14 February 2020

A three-dimensional single-cell-resolution whole-brain atlas using CUBIC-X expansion microscopy and tissue clearing.

artículo científico publicado en 2018

Amido-bridged nucleic acid (AmNA)-modified antisense oligonucleotides targeting α-synuclein as a novel therapy for Parkinson's disease

artículo científico publicado en 2019

Development of a novel RANKL-based peptide, microglial healing peptide1-AcN (MHP1-AcN), for treatment of ischemic stroke

artículo científico publicado en 2018

Gut environment-induced intraepithelial autoreactive CD4(+) T cells suppress central nervous system autoimmunity via LAG-3.

artículo científico publicado en 2016

Inhibition of RGMa alleviates symptoms in a rat model of neuromyelitis optica

artículo científico publicado en 2018

Myasthenia gravis-specific aberrant neuromuscular gene expression by medullary thymic epithelial cells in thymoma

artículo científico publicado en 2022

New 5-Aryl-Substituted 2-Aminobenzamide-Type HDAC Inhibitors with a Diketopiperazine Group and Their Ameliorating Effects on Ischemia-Induced Neuronal Cell Death

artículo científico publicado en 2018

Parkinson's disease and iron

scientific article published on 05 February 2020

Single injection of sustained-release prostacyclin analog ONO-1301-MS ameliorates hypoxic toxicity in the murine model of amyotrophic lateral sclerosis

article

Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy.

artículo científico publicado en 2016

Suppression of autophagic activity by Rubicon is a signature of aging

artículo científico publicado en 2019

Ultrasonication-based rapid amplification of α-synuclein aggregates in cerebrospinal fluid

artículo científico publicado en 2019

β-arrestin-2 in PAR-1-biased signaling has a crucial role in endothelial function via PDGF-β in stroke

article

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