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A Case of Acute Adrenal Insufficiency Unmasked During Sunitinib Treatment for Metastatic Renal Cell Carcinoma ⬇️

artículo científico publicado el 11 de mayo de 2012

A Rare Coexistence of Pheochromocytoma and Parkinson's Disease With Diagnostic Challenges.

artículo científico publicado en 2017

A candidate functional SNP rs7074440 in TCF7L2 alters gene expression through C-FOS in hepatocytes.

artículo científico publicado en 2018

A distinct function of the retinoblastoma protein in the control of lipid composition identified by lipidomic profiling

artículo científico publicado en 2017

A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes

artículo científico publicado en 2017

A kindred of familial acromegaly without evidence for linkage to MEN-1 locus

artículo científico publicado en 2002

A novel processing system of sterol regulatory element-binding protein-1c regulated by polyunsaturated fatty acid

artículo científico publicado en 2014

A transcription factor of lipid synthesis, sterol regulatory element-binding protein (SREBP)-1a causes G(1) cell-cycle arrest after accumulation of cyclin-dependent kinase (cdk) inhibitors

artículo científico publicado en 2007

Abdominal Irradiation Ameliorates Obesity in ob/ob Mice

artículo científico publicado en 2007

Ablation of Elovl6 protects pancreatic islets from high-fat diet-induced impairment of insulin secretion

artículo científico publicado en 2014

Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr(-/-) mouse model

artículo científico publicado en 2015

Absence of hormone-sensitive lipase inhibits obesity and adipogenesis in Lep ob/ob mice

artículo científico

Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice

artículo científico publicado en 2002

Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status

scientific journal article

Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2 ⬇️

artículo científico publicado el 1 de junio de 1998

Adiponectin and adiponectin receptors in human pheochromocytoma.

artículo científico publicado en 2009

Age-dependent changes in dynamic standing-balance ability evaluated quantitatively using a stabilometer

artículo científico publicado en 2018

Antioxidants and an inhibitor of advanced glycation ameliorate death of retinal microvascular cells in diabetic retinopathy

artículo científico publicado en 2006

Association between Lysosomal Dysfunction and Obesity-Related Pathology: A Key Knowledge to Prevent Metabolic Syndrome

artículo científico publicado en 2019

Association between all-cause mortality and severity of depressive symptoms in patients with type 2 diabetes: Analysis from the Japan Diabetes Complications Study (JDCS).

artículo científico publicado en 2017

Association between physical activity and risk of all-cause mortality and cardiovascular disease in patients with diabetes: a meta-analysis.

artículo científico publicado en 2013

Association of Helicobacter pylori infection with glycemic control in patients with diabetes: a meta-analysis

artículo científico publicado en 2014

Association of eating three meals irregularly with changes in BMI and weight among young Japanese men and women: A 2-year follow-up

artículo científico publicado en 2016

Bioactive TNIIIA2 Sequence in Tenascin-C Is Responsible for Macrophage Foam Cell Transformation; Potential of FNIII14 Peptide Derived from Fibronectin in Suppression of Atherosclerotic Plaque Formation

artículo científico publicado en 2024

CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα.

artículo científico publicado en 2016

CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms

scientific article published on 21 February 2020

Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: a meta-analysis

artículo científico publicado en 2009

Carotid artery plaque and LDL-to-HDL cholesterol ratio predict atherosclerotic status in coronary arteries in asymptomatic patients with type 2 diabetes mellitus.

artículo científico publicado en 2013

Cerebral hemorrhagic infarction after radiation for pituitary adenoma.

artículo científico publicado en 2002

Cholesterol accumulation and diabetes in pancreatic beta-cell-specific SREBP-2 transgenic mice: a new model for lipotoxicity

artículo científico publicado en 2008

Cholesterol feeding reduces nuclear forms of sterol regulatory element binding proteins in hamster liver ⬇️

artículo científico publicado el 11 de noviembre de 1997

Cholesterol lowering in low density lipoprotein receptor knockout mice overexpressing apolipoprotein E ⬇️

artículo científico publicado el 15 de julio de 1998

Cide-a and Cide-c are induced in the progression of hepatic steatosis and inhibited by eicosapentaenoic acid

artículo científico publicado en 2010

Circulating malondialdehyde-modified LDL-related variables and coronary artery stenosis in asymptomatic patients with type 2 diabetes

artículo científico publicado en 2015

Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs.

artículo científico publicado en 2002

Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma

artículo científico publicado en 2005

Comparison of baseline characteristics and clinical course in Japanese patients with type 2 diabetes among whom different types of oral hypoglycemic agents were chosen by diabetes specialists as initial monotherapy (JDDM 42).

artículo científico publicado en 2017

Comparison of clinical characteristics in patients with type 2 diabetes among whom different antihyperglycemic agents were prescribed as monotherapy or combination therapy by diabetes specialists.

artículo científico publicado en 2015

Comparison of the Framingham risk score, UK Prospective Diabetes Study (UKPDS) Risk Engine, Japanese Atherosclerosis Longitudinal Study-Existing Cohorts Combine (JALS-ECC) and maximum carotid intima-media thickness for predicting coronary artery ste

artículo científico publicado en 2014

Comparisons of the strength of associations with future type 2 diabetes risk among anthropometric obesity indicators, including waist-to-height ratio: a meta-analysis.

artículo científico publicado en 2012

Critical role of CREBH-mediated induction of TGF-β2 by HCV infection in fibrogenic responses in hepatic stellate cells

artículo científico publicado en 2017

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of L

artículo científico publicado en 2003

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling

artículo científico publicado en 2003

Crucial Role of Elovl6 in Chondrocyte Growth and Differentiation during Growth Plate Development in Mice

artículo científico publicado en 2016

Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance.

artículo científico publicado en 2007

Cyclin-dependent kinase inhibitor, p21WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance.

artículo científico publicado en 2008

Deciphering genetic signatures by whole exome sequencing in a case of co-prevalence of severe renal hypouricemia and diabetes with impaired insulin secretion

scientific article published on 06 May 2020

Development of a screening score for undiagnosed diabetes and its application in estimating absolute risk of future type 2 diabetes in Japan: Toranomon Hospital Health Management Center Study 10 (TOPICS 10).

artículo científico publicado en 2013

Diabetes and risk of hearing impairment in adults: a meta-analysis.

artículo científico publicado en 2012

Diabetes mellitus and risk of new-onset and recurrent heart failure: a systematic review and meta-analysis

artículo científico publicado en 2020

Dicer has a crucial role in the early stage of adipocyte differentiation, but not in lipid synthesis, in 3T3-L1 cells

artículo científico publicado en 2012

Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice

artículo científico publicado en 2016

Distinct regulation of plasma LDL cholesterol by eicosapentaenoic acid and docosahexaenoic acid in high fat diet-fed hamsters: participation of cholesterol ester transfer protein and LDL receptor

artículo científico publicado en 2013

Dual regulation of mouse Delta(5)- and Delta(6)-desaturase gene expression by SREBP-1 and PPARalpha

artículo científico publicado en 2002

Early embryonic lethality caused by targeted disruption of the 3-hydroxy-3-methylglutaryl-CoA reductase gene

scientific journal article

Effect of Macrophage Colony Stimulating Factor on the Advanced Atherosclerosis in Watanabe Heritable Hyperlipidemic Rabbits ⬇️

artículo científico publicado el 1 de octubre de 1997

Effect of postmenopausal status and age at menopause on type 2 diabetes and prediabetes in Japanese individuals: Toranomon Hospital Health Management Center Study 17 (TOPICS 17).

scientific article published on 29 October 2013

Effect of sodium-glucose cotransporter 2 (SGLT2) inhibition on weight loss is partly mediated by liver-brain-adipose neurocircuitry.

artículo científico publicado en 2017

Effect of thiazolidinediones and metformin on LDL oxidation and aortic endothelium relaxation in diabetic GK rats

artículo científico publicado en 2003

Effects of K-877, a novel selective PPARα modulator, on small intestine contribute to the amelioration of hyperlipidemia in low-density lipoprotein receptor knockout mice

artículo científico publicado en 2017

Effects of atorvastatin on glucose metabolism and insulin resistance in KK/Ay mice

artículo científico publicado en 2005

Effects of pitavastatin (LIVALO Tablet) on high density lipoprotein cholesterol (HDL-C) in hypercholesterolemia

artículo científico publicado en 2009

Effects of pitavastatin (LIVALO tablet) on the estimated glomerular filtration rate (eGFR) in hypercholesterolemic patients with chronic kidney disease. Sub-analysis of the LIVALO Effectiveness and Safety (LIVES) Study

artículo científico publicado en 2010

Efficacy and safety of pitavastatin in Japanese patients with hypercholesterolemia: LIVES study and subanalysis

artículo científico publicado en 2011

Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene ⬇️

artículo científico publicado el 15 de octubre de 1997

Elimination of cholesterol ester from macrophage foam cells by adenovirus-mediated gene transfer of hormone-sensitive lipase.

artículo científico publicado en 2002

Elovl6 Deficiency Improves Glycemic Control in Diabetic db/db Mice by Expanding β-Cell Mass and Increasing Insulin Secretory Capacity.

artículo científico publicado en 2017

Elovl6 promotes nonalcoholic steatohepatitis

artículo científico publicado en 2012

Elovl6: a new player in fatty acid metabolism and insulin sensitivity

artículo científico publicado en 2009

Elucidation of Molecular Mechanism of a Selective PPARα Modulator, Pemafibrate, through Combinational Approaches of X-ray Crystallography, Thermodynamic Analysis, and First-Principle Calculations

scientific article published on 06 January 2020

Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis via SREBP Competitive Inhibition

artículo científico publicado en 2020

Erratum: Deranged fatty acid composition causes pulmonary fibrosis in Elovl6-deficient mice

scientific article published in Nature Communications

Estimated Stearoyl-CoA-desaturase (SCD)-1 and Elongase of Very Long Chain Fatty Acids (Elovl) 6 Activities From Serum Fatty Acids Are Reciprocally Associated with Visceral Fat Area in Type 2 Diabetic Patients

scholarly article

Estrogen receptor ligands ameliorate fatty liver through a nonclassical estrogen receptor/Liver X receptor pathway in mice

artículo científico publicado en 2014

Exercise training reduces ventricular arrhythmias through restoring calcium handling and sympathetic tone in myocardial infarction mice

scientific article published on 01 February 2019

Exploratory analysis using machine learning of predictive factors for falls in type 2 diabetes

artículo científico publicado en 2022

FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products.

artículo científico publicado en 2002

Fasting and post-challenge glucose as quantitative cardiovascular risk factors: a meta-analysis.

artículo científico publicado en 2012

GLUT12: a second insulin-responsive glucose transporters as an emerging target for type 2 diabetes

artículo científico publicado en 2012

Glucocorticoid receptor suppresses gene expression of Rev-erbα (Nr1d1) through interaction with the CLOCK complex

scientific article published on 01 February 2019

Glycogen shortage during fasting triggers liver-brain-adipose neurocircuitry to facilitate fat utilization

artículo científico publicado en 2013

Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice

scientific journal article

Guidelines on the Clinical Evaluation of Medicinal Products for Treatment of Dyslipidemia

scientific article published on 28 August 2020

HMG-CoA reductase inhibitor decreases small dense low-density lipoprotein and remnant-like particle cholesterol in patients with type-2 diabetes

artículo científico publicado en 2002

HbA1c 5·7-6·4% and impaired fasting plasma glucose for diagnosis of prediabetes and risk of progression to diabetes in Japan (TOPICS 3): a longitudinal cohort study

artículo científico publicado en 2011

Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement

artículo científico publicado en 2003

Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes.

artículo científico publicado en 2014

Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl-Chain Length and Hepatic Insulin Sensitivity in Mice

artículo científico publicado en 2019

High mobility group protein-B1 interacts with sterol regulatory element-binding proteins to enhance their DNA binding

artículo científico publicado en 2005

High risk of failing eradication of Helicobacter pylori in patients with diabetes: A meta-analysis

article

Higher pulse pressure predicts initiation of dialysis in Japanese patients with diabetes

artículo científico publicado en 2019

Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lep ob/ob mice.

artículo científico publicado en 2009

Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis.

artículo científico publicado en 2008

Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system

artículo científico publicado en 2016

Identical germline mutations in the TMEM127 gene in two unrelated Japanese patients with bilateral pheochromocytoma ⬇️

artículo científico publicado el 1 de noviembre de 2012

Identification of ISG12b as a putative interferon-inducible adipocytokine which is highly expressed in white adipose tissue

artículo científico publicado en 2007

Identification of a novel member of the carboxylesterase family that hydrolyzes triacylglycerol: a potential role in adipocyte lipolysis

scientific journal article

Identification of human ELOVL5 enhancer regions controlled by SREBP

artículo científico publicado en 2015

In Search of the Ideal Resistance Training Program to Improve Glycemic Control and its Indication for Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

artículo científico publicado en 2015

In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-1c expression

artículo científico publicado en 2007

Increased cholesterol biosynthesis and hypercholesterolemia in mice overexpressing squalene synthase in the liver

artículo científico publicado en 2006

Induction of ABCA1 by overexpression of hormone-sensitive lipase in macrophages

artículo científico publicado en 2008

Influence of fat and carbohydrate proportions on the metabolic profile in patients with type 2 diabetes: a meta-analysis.

artículo científico publicado en 2009

Inhibition of autophagy enhances sunitinib-induced cytotoxicity in rat pheochromocytoma PC12 cells

artículo científico publicado en 2012

Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice

artículo científico publicado en 2011

Insulin inhibits apoptosis of macrophage cell line, THP-1 cells, via phosphatidylinositol-3-kinase-dependent pathway

artículo científico publicado en 2002

Insulin-dependent and -independent regulation of sterol regulatory element-binding protein-1c

artículo científico publicado en 2013

Insulin-independent induction of sterol regulatory element-binding protein-1c expression in the livers of streptozotocin-treated mice

artículo científico publicado en 2004

Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression.

artículo científico publicado en 2016

Involvement of glomerular SREBP-1c in diabetic nephropathy

artículo científico publicado en 2007

KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting.

artículo científico publicado en 2016

Ligand-activated PPARα-dependent DNA demethylation regulates the fatty acid β-oxidation genes in the postnatal liver

artículo científico publicado en 2014

Lipid synthetic transcription factor SREBP-1a activates p21WAF1/CIP1, a universal cyclin-dependent kinase inhibitor

artículo científico publicado en 2005

Lipolysis in the absence of hormone-sensitive lipase: evidence for a common mechanism regulating distinct lipases

artículo científico publicado en 2002

Logistic regression analysis for identifying the factors affecting development of non-invasive blood glucose calibration model by near-infrared spectroscopy

scientific article published in 2015

Longitudinal trajectories of HbA1c and fasting plasma glucose levels during the development of type 2 diabetes: the Toranomon Hospital Health Management Center Study 7 (TOPICS 7)

artículo científico publicado en 2012

Loss of SDHB Elevates Catecholamine Synthesis and Secretion Depending on ROS Production and HIF Stabilization

artículo científico publicado en 2015

Low lung function and risk of type 2 diabetes in Japanese men: the Toranomon Hospital Health Management Center Study 9 (TOPICS 9)

artículo científico publicado en 2012

Macrophage Elovl6 Deficiency Ameliorates Foam Cell Formation and Reduces Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice

artículo científico publicado en 2011

MafB promotes atherosclerosis by inhibiting foam-cell apoptosis

artículo científico publicado en 2014

MafK overexpression in pancreatic beta-cells caused impairment of glucose-stimulated insulin secretion

artículo científico publicado en 2006

Malondialdehyde-modified LDL-related variables are associated with diabetic kidney disease in type 2 diabetes

scientific article published on 26 May 2018

Meta-analytic research on the relationship between cumulative risk alleles and risk of type 2 diabetes mellitus.

artículo científico publicado en 2015

MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice. ⬇️

artículo científico publicado en 2013

MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo

artículo científico publicado en 2014

Mitochondrial intermediate peptidase is a novel regulator of sirtuin-3 activation by caloric restriction

artículo científico publicado en 2017

Molecular mechanisms involved in hepatic steatosis and insulin resistance

artículo científico publicado en 2011

Mouse Elovl-6 promoter is an SREBP target

artículo científico publicado en 2008

Mouse MafA, homologue of zebrafish somite Maf 1, contributes to the specific transcriptional activity through the insulin promoter

scientific journal article

New evidence on pitavastatin: efficacy and safety in clinical studies

artículo científico publicado en 2010

New liver-β-cell axis that controls insulin secretory capacity

artículo científico publicado en 2014

Novel qualitative aspects of tissue fatty acids related to metabolic regulation: Lessons from Elovl6 knockout ⬇️

artículo científico publicado el 13 de enero de 2012

Novel role for the CRTC2 in lipid homeostasis

artículo científico publicado en 2016

Nuclear SREBP-1a causes loss of pancreatic beta-cells and impaired insulin secretion

artículo científico publicado en 2008

Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism

artículo científico publicado en 2019

PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity

artículo científico publicado en 2003

PPAR gamma ligands, troglitazone and pioglitazone, up-regulate expression of HMG-CoA synthase and HMG-CoA reductase gene in THP-1 macrophages

artículo científico publicado en 2002

Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets

artículo científico publicado en 2008

Physiological changes in circulating mannose levels in normal, glucose-intolerant, and diabetic subjects

artículo científico publicado en 2003

Plasma chloride concentration as a new diagnostic indicator of insulin insufficiency

artículo científico publicado en 2005

Plasma free metanephrines in the diagnosis of pheochromocytoma: diagnostic accuracy and strategies for Japanese patients

artículo científico publicado en 2014

Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression

artículo científico

Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.

artículo científico publicado en 2010

Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements

artículo científico publicado en 2001

Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver

artículo científico publicado en 2007

Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin.

artículo científico publicado en 2010

Quality and accuracy of Internet information concerning a healthy diet.

artículo científico publicado en 2013

Quality of Internet information related to the Mediterranean diet

artículo científico publicado en 2011

Quantitative Relationship Between Cumulative Risk Alleles Based on Genome-Wide Association Studies and Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis.

artículo científico publicado en 2017

Quantitative assessment of genetic testing for type 2 diabetes mellitus based on findings of genome-wide association studies.

artículo científico publicado en 2016

Rapid manipulation of mitochondrial morphology in a living cell with iCMM

artículo científico publicado en 2021

Receptor-type protein tyrosine phosphatase epsilon (PTPepsilonM) is a negative regulator of insulin signaling in primary hepatocytes and liver

scientific journal article

Regulation of hepatic cholesterol synthesis by a novel protein (SPF) that accelerates cholesterol biosynthesis

artículo científico publicado en 2006

Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice ⬇️

artículo científico publicado el 26 de mayo de 1998

Relationship between intake of fruit separately from vegetables and triglycerides - A meta-analysis

scientific article published on 13 July 2018

Relationships among cardiorespiratory fitness, muscular fitness, and cardiometabolic risk factors in Japanese adolescents: Niigata screening for and preventing the development of non-communicable disease study-Agano (NICE EVIDENCE Study-Agano) 2.

artículo científico publicado en 2017

Resistin is regulated by C/EBPs, PPARs, and signal-transducing molecules

artículo científico publicado en 2002

Rho-associated, coiled-coil-containing protein kinase 1 as a new player in the regulation of hepatic lipogenesis

artículo científico publicado en 2019

Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at endoplasmic reticulum monitoring and regulating fatty acids

artículo científico publicado en 2023

Risk imparted by various parameters of smoking in Japanese men with type 2 diabetes on their development of microalbuminuria: analysis from the Tsukuba Kawai Diabetes Registry

artículo científico publicado en 2007

Role of Apolipoprotein E in Lipoprotein Metabolism and in the Process of Atherosclerosis ⬇️

artículo científico publicado el 1 de enero de 1995

Role of Hormone-sensitive Lipase in Leptin-Promoted Fat Loss and Glucose Lowering

artículo científico publicado en 2017

Role of alcohol drinking pattern in type 2 diabetes in Japanese men: the Toranomon Hospital Health Management Center Study 11 (TOPICS 11).

artículo científico publicado en 2013

SPARC is a major secretory gene expressed and involved in the development of proliferative diabetic retinopathy

artículo científico publicado en 2009

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.

artículo científico publicado en 2004

SREBP-1-independent regulation of lipogenic gene expression in adipocytes

artículo científico publicado en 2007

SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism

artículo científico publicado en 2016

SREBPs suppress IRS-2-mediated insulin signalling in the liver

artículo científico publicado en 2004

Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages.

artículo científico publicado en 2018

Scavenger receptor expressed by endothelial cells I (SREC-I) mediates the uptake of acetylated low density lipoproteins by macrophages stimulated with lipopolysaccharide

artículo científico publicado en 2004

Selective peroxisome proliferator-activated receptor-α modulator K-877 efficiently activates the peroxisome proliferator-activated receptor-α pathway and improves lipid metabolism in mice.

artículo científico publicado en 2017

Self-reported fast eating is a potent predictor of development of impaired glucose tolerance in Japanese men and women: Tsukuba Medical Center Study

artículo científico publicado en 2011

Skeletal muscle-specific HMG-CoA reductase knockout mice exhibit rhabdomyolysis: A model for statin-induced myopathy

artículo científico publicado en 2015

Skipping breakfast and prevalence of overweight and obesity in Asian and Pacific regions: a meta-analysis.

artículo científico

Srebp-1c/Fgf21/Pgc-1α Axis Regulated by Leptin Signaling in Adipocytes-Possible Mechanism of Caloric Restriction-Associated Metabolic Remodeling of White Adipose Tissue

artículo científico publicado en 2020

Statins downregulate ATP-binding-cassette transporter A1 gene expression in macrophages

artículo científico publicado en 2004

Sterol Regulatory Element–Binding Protein-1 Determines Plasma Remnant Lipoproteins and Accelerates Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

artículo científico publicado en 2011

Sterol regulatory element-binding protein-2 interacts with hepatocyte nuclear factor-4 to enhance sterol isomerase gene expression in hepatocytes

artículo científico publicado en 2003

Sterol regulatory element-binding proteins activate insulin gene promoter directly and indirectly through synergy with BETA2/E47.

artículo científico publicado en 2005

Subendocardial Systolic Dysfunction in Asymptomatic Normotensive Diabetic Patients

artículo científico publicado en 2015

Sunitinib induces apoptosis in pheochromocytoma tumor cells by inhibiting VEGFR2/Akt/mTOR/S6K1 pathways through modulation of Bcl-2 and BAD.

artículo científico publicado en 2011

Sunitinib inhibits catecholamine synthesis and secretion in pheochromocytoma tumor cells by blocking VEGF receptor 2 via PLC-γ-related pathways

artículo científico publicado en 2012

Suppression of the pancreatic duodenal homeodomain transcription factor-1 (Pdx-1) promoter by sterol regulatory element-binding protein-1c (SREBP-1c).

artículo científico publicado en 2011

TFE3 controls lipid metabolism in adipose tissue of male mice by suppressing lipolysis and thermogenesis

artículo científico publicado en 2013

TFE3 inhibits myoblast differentiation in C2C12 cells via down-regulating gene expression of myogenin.

artículo científico publicado en 2012

TFE3 regulates muscle metabolic gene expression, increases glycogen stores, and enhances insulin sensitivity in mice

artículo científico publicado en 2012

TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes

artículo científico publicado en 2005

TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

scientific article published on 21 June 2009

The Relationship between Diabetic Neuropathy and Sleep Apnea Syndrome: A Meta-Analysis

artículo científico publicado en 2013

The liver-enriched transcription factor CREBH is nutritionally regulated and activated by fatty acids and PPARalpha.

artículo científico

The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential : A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction

scientific article published on 04 June 2019

The up-regulation of microRNA-335 is associated with lipid metabolism in liver and white adipose tissue of genetically obese mice

artículo científico publicado en 2009

Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genes

scientific journal article

Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT1

scientific article published on 19 December 2019

Transgenic Mice Overexpressing SREBP-1a in Male ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance

scientific article published on 01 June 2018

Transgenic mice overexpressing SREBP-1a under the control of the PEPCK promoter exhibit insulin resistance, but not diabetes

artículo científico publicado en 2004

Transgenic mice overexpressing nuclear SREBP-1c in pancreatic beta-cells

artículo científico publicado en 2005

Unstable bodyweight and incident type 2 diabetes mellitus: A meta-analysis.

artículo científico publicado en 2017

Use of high-normal levels of haemoglobin A(1C) and fasting plasma glucose for diabetes screening and for prediction: a meta-analysis

artículo científico publicado en 2013

Utility of nonblood-based risk assessment for predicting type 2 diabetes mellitus: A meta-analysis

artículo científico publicado en 2016

Utility of the triglyceride level for predicting incident diabetes mellitus according to the fasting status and body mass index category: the Ibaraki Prefectural Health Study.

artículo científico publicado en 2014

WGEF is a novel RhoGEF expressed in intestine, liver, heart, and kidney.

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