Lista de obras -

A Randomized Controlled Trial on the Effect of Tapentadol and Morphine on Conditioned Pain Modulation in Healthy Volunteers

artículo científico publicado en 2015

A comparison of the central nervous system effects of alcohol at pseudo-steady state in Caucasian and expatriate Japanese healthy male volunteers

artículo científico publicado en 2012

A pragmatic utility function to describe the risk-benefit composite of opioid and non-opioid analgesic medication

artículo científico publicado en 2018

A randomised controlled trial on the efficacy and side-effect profile (nausea/vomiting/sedation) of morphine-6-glucuronide versus morphine for post-operative pain relief after major abdominal surgery

artículo científico publicado en 2010

A randomized, double-blind, placebo-controlled pilot study of IV morphine-6-glucuronide for postoperative pain relief after knee replacement surgery

artículo científico publicado en 2007

A retrospective study on persistent pain after childbirth in the Netherlands

artículo científico publicado en 2016

ARA 290 for treatment of small fiber neuropathy in sarcoidosis.

artículo científico publicado en 2014

ARA 290, a nonerythropoietic peptide engineered from erythropoietin, improves metabolic control and neuropathic symptoms in patients with type 2 diabetes.

artículo científico publicado en 2014

ARA290, a peptide derived from the tertiary structure of erythropoietin, produces long-term relief of neuropathic pain: an experimental study in rats and β-common receptor knockout mice.

artículo científico publicado en 2011

Ability of the nociception level, a multiparameter composite of autonomic signals, to detect noxious stimuli during propofol-remifentanil anesthesia

artículo científico publicado en 2015

Absence of long-term analgesic effect from a short-term S-ketamine infusion on fibromyalgia pain: a randomized, prospective, double blind, active placebo-controlled trial

artículo científico publicado en 2011

Acetazolamide improves cerebral oxygenation during exercise at high altitude

artículo científico publicado en 2006

Acute and chronic fentanyl administration causes hyperalgesia independently of opioid receptor activity in mice

artículo científico publicado en 2009

Alfentanil and placebo analgesia: no sex differences detected in models of experimental pain

artículo científico publicado en 2005

An experimental randomized study on the analgesic effects of pharmaceutical-grade cannabis in chronic pain patients with fibromyalgia

scientific article published on 01 April 2019

An observational study on the effect of S+-ketamine on chronic pain versus experimental acute pain in Complex Regional Pain Syndrome type 1 patients.

artículo científico publicado en 2009

Analgesic and Respiratory Depressant Effects of R-dihydroetorphine: A Pharmacokinetic-Pharmacodynamic Analysis in Healthy Male Volunteers

scientific article published on 01 December 2019

Analysis of cerebrospinal fluid inflammatory mediators in chronic complex regional pain syndrome related dystonia

artículo científico publicado en 2008

Animal-to-human extrapolation of the pharmacokinetic and pharmacodynamic properties of buprenorphine

artículo científico publicado en 2007

Antioxidants prevent blunting of hypoxic ventilatory response by low-dose halothane.

artículo científico publicado en 2004

Antioxidants prevent depression of the acute hypoxic ventilatory response by subanaesthetic halothane in men.

artículo científico publicado en 2002

Antioxidants reverse depression of the hypoxic ventilatory response by acetazolamide in man.

artículo científico publicado en 2006

Antioxidants reverse reduction of the human hypoxic ventilatory response by subanesthetic isoflurane

artículo científico publicado en 2005

Arterial Line Placement: Safety First

artículo científico publicado en 2016

Arterial [H+] and the ventilatory response to hypoxia in humans: influence of acetazolamide-induced metabolic acidosis

artículo científico publicado en 2009

Arterial and venous pharmacokinetics of morphine-6-glucuronide and impact of sample site on pharmacodynamic parameter estimates

artículo científico publicado en 2010

Assessment of allodynia relief by tissue-protective molecules in a rat model of nerve injury-induced neuropathic pain

artículo científico publicado en 2013

Assessment of middle cerebral artery diameter during hypocapnia and hypercapnia in humans using ultra-high-field MRI.

artículo científico publicado en 2014

Averting Opioid-induced Respiratory Depression without Affecting Analgesia

artículo científico publicado en 2018

Benefit and Risk Evaluation of Biased μ-Receptor Agonist Oliceridine versus Morphine

artículo científico publicado en 2020

Benefit versus Severe Side Effects of Opioid Analgesia: Novel Utility Functions of Probability of Analgesia and Respiratory Depression.

artículo científico publicado en 2018

Big brain, small world?

artículo científico publicado en 2015

Bispectral index values and spectral edge frequency at different stages of physiologic sleep

artículo científico publicado en 2002

Cannabis-opioid interaction in the treatment of fibromyalgia pain: an open-label, proof of concept study with randomization between treatment groups: cannabis, oxycodone or cannabis/oxycodone combination—the SPIRAL study

artículo científico publicado en 2023

Carotid body tumors in humans caused by a mutation in the gene for succinate dehydrogenase D (SDHD).

artículo científico publicado en 2004

Causes and consequences of the opioid epidemic in the Netherlands: a population-based cohort study

scientific article published on 17 September 2020

Cholinergic Chemotransmission and Anesthetic Drug Effects at the Carotid Bodies

artículo científico publicado en 2020

Cibinetide Improves Corneal Nerve Fiber Abundance in Patients With Sarcoidosis-Associated Small Nerve Fiber Loss and Neuropathic Pain.

artículo científico publicado en 2017

Circadian influences, low-dose isoflurane, and the ventilatory response to hypoxia

artículo científico publicado en 2005

Combined Recirculatory-compartmental Population Pharmacokinetic Modeling of Arterial and Venous Plasma S(+) and R(-) Ketamine Concentrations

artículo científico publicado en 2018

Comment on Rosenberg J, et al.: "Deep Neuromuscular Blockade Improves Laparoscopic Surgical Conditions: A Randomized, Controlled Study".

artículo científico publicado en 2017

Comorbidities and the complexities of chronic pain.

artículo científico publicado en 2014

Comparison of Two Different Analgesic Prescription Strategies and Healthcare Systems: Slovenia vs. the Netherlands

artículo científico publicado en 2021

Cornea nerve fiber quantification and construction of phenotypes in patients with fibromyalgia.

artículo científico publicado en 2016

Cornea nerve fibre state determines analgesic response to tapentadol in fibromyalgia patients without effective endogenous pain modulation

scientific article published on 24 June 2019

Corneal nerve fiber size adds utility to the diagnosis and assessment of therapeutic response in patients with small fiber neuropathy.

artículo científico publicado en 2018

Deep Neuromuscular Block Improves Surgical Conditions during Bariatric Surgery and Reduces Postoperative Pain: A Randomized Double Blind Controlled Trial

artículo científico publicado en 2016

Deep Neuromuscular Block and Surgical Conditions During Bariatric Surgery

artículo científico publicado en 2017

Deep neuromuscular block does not improve surgical conditions in patients receiving sevoflurane anaesthesia for laparoscopic renal surgery

scientific article published on 19 October 2020

Developmental changes in morphine clearance across the entire paediatric age range are best described by a bodyweight-dependent exponent model.

artículo científico publicado en 2013

Differences between opioids: pharmacological, experimental, clinical and economical perspectives

artículo científico publicado en 2013

Differential effect of morphine and morphine-6-glucuronide on the control of breathing in the anesthetized cat.

artículo científico publicado en 2008

Do sex differences exist in opioid analgesia? A systematic review and meta-analysis of human experimental and clinical studies

artículo científico publicado en 2010

Does deep neuromuscular block affect pain after laparoscopic surgery?

artículo científico publicado en 2017

Does nociception monitor-guided anesthesia affect opioid consumption? A systematic review of randomized controlled trials

scientific article published on 20 July 2019

Drug-induced liver injury following a repeated course of ketamine treatment for chronic pain in CRPS type 1 patients: a report of 3 cases

artículo científico publicado en 2011

Early postoperative pain after laparoscopic donor nephrectomy predicts 30-day postoperative infectious complications: a pooled analysis of randomized controlled trials

artículo científico publicado en 2020

Effect of Rifampicin on S-ketamine and S-norketamine Plasma Concentrations in Healthy Volunteers after Intravenous S-ketamine Administration ⬇️

artículo científico publicado el 1 de junio de 2011

Effect of deafferentation from spinal anesthesia on pain sensitivity and resting-state functional brain connectivity in healthy male volunteers.

artículo científico publicado en 2014

Effect of ketamine on endogenous pain modulation in healthy volunteers.

artículo científico publicado en 2011

Effect of subanesthetic ketamine on intrinsic functional brain connectivity: a placebo-controlled functional magnetic resonance imaging study in healthy male volunteers

artículo científico publicado en 2012

Efficacy and safety of morphine-6-glucuronide (M6G) for postoperative pain relief: a randomized, double-blind study

artículo científico publicado en 2008

Efficacy of profound versus moderate neuromuscular blockade in enhancing postoperative recovery after laparoscopic donor nephrectomy: A randomised controlled trial

scientific article published on 01 July 2019

Endogenous modulation of pain is visible in the brain

artículo científico publicado en 2011

Endogenous pain modulation: from humans to animals and back

artículo científico publicado en 2015

Epidural Blockade Affects the Pharmacokinetics of Propofol in Surgical Patients

artículo científico publicado en 2015

Epidural and Non-epidural Analgesia in Patients Undergoing Open Pancreatectomy: a Retrospective Cohort Study

scientific article published on 26 February 2019

Erratum to: Quality of Recovery After Low-Pressure Laparoscopic Donor Nephrectomy Facilitated by Deep Neuromuscular Blockade: A Randomized Controlled Study

scientific article published on 01 November 2017

Evaluating Patient-Centered Outcomes in Clinical Trials of Procedural Sedation, Part 2 Safety: Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research Recommendations

article

Fentanyl utility function: a risk-benefit composite of pain relief and breathing responses

artículo científico publicado en 2013

Frequent respiratory events in postoperative patients aged 60 years and above

artículo científico publicado en 2017

From breathtaking to encapsulation: a novel approach to reverse respiratory depression from opioid overdosing

scientific article published on 27 April 2020

Functional biomarkers for the acute effects of alcohol on the central nervous system in healthy volunteers

artículo científico publicado en 2011

Gender differences in morphine pharmacokinetics and dynamics.

artículo científico publicado en 2003

Handheld Retinal Oximetry in Healthy Young Adults

scientific article published on 01 July 2018

Health-related quality of life in 975 patients with complex regional pain syndrome type 1.

artículo científico publicado en 2013

Hospital variation in allogeneic transfusion and extended length of stay in primary elective hip and knee arthroplasty: a cross-sectional study

artículo científico

Hyperalgesia and Reduced Offset Analgesia During Spinal Anesthesia

scientific article published on 24 August 2020

Impact of high- versus low-dose neuromuscular blocking agent administration on unplanned 30-day readmission rates in retroperitoneal laparoscopic surgery.

artículo científico publicado en 2018

Improvements in the application and reporting of advanced Bland-Altman methods of comparison

artículo científico publicado en 2014

Improving detection of patient deterioration in the general hospital ward environment

artículo científico publicado en 2018

In Response

scientific article published on 01 August 2019

Incidence, Reversal, and Prevention of Opioid-induced Respiratory Depression

artículo científico publicado en 2010

Increased margin of safety of morphine-6-glucuronide relative to morphine

artículo científico publicado en 2004

Influence of Acute Pain Induced by Activation of Cutaneous Nociceptors on Ventilatory Control ⬇️

artículo científico publicado el 1 de agosto de 1997

Influence of Ethanol on Oxycodone-induced Respiratory Depression: A Dose-escalating Study in Young and Elderly Individuals.

artículo científico publicado en 2017

Influence of propofol on the control of breathing.

artículo científico publicado en 2003

Influences of Subanesthetic Isoflurane on Ventilatory Control in Humans ⬇️

artículo científico publicado el 1 de septiembre de 1995

Inspired carbon dioxide during hypoxia: effects on task performance and cerebral oxygen saturation.

artículo científico publicado en 2007

Ketamine Pharmacokinetics

scientific article published on 30 September 2020

Ketamine for chronic pain: risks and benefits

artículo científico publicado en 2014

Ketamine for neuropathic pain: a tiger that won't bite?

artículo científico publicado en 2020

Ketamine for pain.

artículo científico publicado en 2017

Ketamine for the treatment of chronic non-cancer pain

artículo científico publicado en 2010

Ketamine interactions with biomarkers of stress: a randomized placebo-controlled repeated measures resting-state fMRI and PCASL pilot study in healthy men.

artículo científico publicado en 2014

Ketamine metabolomics in the treatment of major depression.

artículo científico publicado en 2014

Low bispectral index values in awake volunteers receiving a combination of propofol and midazolam

artículo científico publicado en 2004

Low-dose acetazolamide reduces the hypoxic ventilatory response in the anesthetized cat.

artículo científico publicado en 2004

Mechanism-based pharmacokinetic-pharmacodynamic modeling of the antinociceptive effect of buprenorphine in healthy volunteers

scientific article published on 01 June 2006

Mechanism-based pharmacokinetic-pharmacodynamic modeling of the respiratory-depressant effect of buprenorphine and fentanyl in rats

artículo científico publicado en 2006

Mechanism-based pharmacokinetic-pharmacodynamic modelling of the reversal of buprenorphine-induced respiratory depression by naloxone : a study in healthy volunteers

artículo científico publicado en 2007

Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception

artículo científico publicado en 2005

Mixed-effects modeling of the influence of midazolam on propofol pharmacokinetics

artículo científico publicado en 2009

Modeling the non-steady state respiratory effects of remifentanil in awake and propofol-sedated healthy volunteers

artículo científico publicado en 2010

Morphine induces hyperalgesia without involvement of μ-opioid receptor or morphine-3-glucuronide

artículo científico publicado en 2012

Morphine-6-glucuronide (M6G) for postoperative pain relief

artículo científico publicado en 2007

Morphine-6-glucuronide: morphine's successor for postoperative pain relief?

artículo científico publicado en 2006

Morphine-6-glucuronide: potency and safety compared with morphine

artículo científico publicado en 2008

Morphine-6beta-glucuronide rapidly increases pain sensitivity independently of opioid receptor activity in mice and humans

artículo científico publicado en 2009

NMDA receptor antagonists for the treatment of neuropathic pain ⬇️

artículo científico publicado el 1 de noviembre de 2010

Naloxone reversal of buprenorphine-induced respiratory depression

scientific article published on 01 July 2006

Naloxone reversal of morphine- and morphine-6-glucuronide-induced respiratory depression in healthy volunteers: a mechanism-based pharmacokinetic-pharmacodynamic modeling study

artículo científico publicado en 2010

Naloxone reversal of opioid-induced respiratory depression with special emphasis on the partial agonist/antagonist buprenorphine

artículo científico publicado en 2008

Naloxone treatment in opioid addiction: the risks and benefits

artículo científico publicado en 2007

New-Onset Atrial Fibrillation Detected by Continuous Capnography Monitoring: A Case Report

scientific article published on 19 September 2020

Nociception level monitoring for personalized analgesic treatment. Response to Br J Anaesth 2020; 125: 1070-8

artículo científico publicado en 2020

Nociception-guided versus Standard Care during Remifentanil-Propofol Anesthesia: A Randomized Controlled Trial

artículo científico publicado en 2019

Non-analgesic effects of opioids: opioid-induced respiratory depression

artículo científico publicado en 2012

Objective markers of the analgesic response to morphine in experimental pain research

artículo científico publicado en 2015

Offset analgesia in neuropathic pain patients and effect of treatment with morphine and ketamine.

artículo científico publicado en 2011

Opioid Prescription Patterns and Risk Factors Associated With Opioid Use in the Netherlands

scientific article published on 02 August 2019

Opioid chronopharmacology: influence of timing of infusion on fentanyl's analgesic efficacy in healthy human volunteers

artículo científico publicado en 2010

Opioid utility function: methods and implications

scientific article published on 25 November 2019

Opioid-induced respiratory depression in humans: a review of pharmacokinetic-pharmacodynamic modelling of reversal

scientific article published on 01 February 2019

Opioid-induced respiratory depression in the acute care setting: a compendium of case reports

artículo científico publicado en 2014

Opioid-induced respiratory depression: reversal by non-opioid drugs

artículo científico publicado en 2014

Opioid-induced respiratory effects: new data on buprenorphine

artículo científico publicado en 2006

Opioids and the management of chronic severe pain in the elderly: consensus statement of an International Expert Panel with focus on the six clinically most often used World Health Organization Step III opioids (buprenorphine, fentanyl, hydromorphon

artículo científico publicado en 2008

Optimal Surgical Conditions in Laparoscopic Surgery: Just Relax and Lower the Pressure

artículo científico publicado en 2016

Pain sensitivity and pain scoring in patients with morbid obesity.

artículo científico publicado en 2017

Perioperative management of obstructive sleep apnea in bariatric surgery: a consensus guideline

artículo científico publicado en 2017

Pharmacodynamic Effect of Morphine-6-glucuronide versus Morphine on Hypoxic and Hypercapnic Breathing in Healthy Volunteers ⬇️

artículo científico publicado el 1 de octubre de 2003

Pharmacodynamic analysis of the analgesic effect of capsaicin 8% patch (Qutenza™) in diabetic neuropathic pain patients: detection of distinct response groups

artículo científico publicado en 2012

Pharmacokinetic and pharmacodynamic considerations for NMDA receptor antagonists in the treatment of chronic neuropathic pain

artículo científico publicado en 2012

Pharmacokinetic and pharmacodynamic considerations for NMDA-receptor antagonist ketamine in the treatment of chronic neuropathic pain: an update of the most recent literature

scientific article published on 13 November 2019

Pharmacokinetic-pharmacodynamic modeling in acute and chronic pain: an overview of the recent literature

artículo científico publicado en 2011

Pharmacokinetic-pharmacodynamic modeling of morphine-6-glucuronide-induced analgesia in healthy volunteers: absence of sex differences

artículo científico publicado en 2004

Pharmacokinetic-pharmacodynamic modeling of the antinociceptive effect of buprenorphine and fentanyl in rats: role of receptor equilibration kinetics

artículo científico publicado en 2005

Pharmacokinetic-pharmacodynamic modeling of the effectiveness and safety of buprenorphine and fentanyl in rats

artículo científico publicado en 2007

Pharmacokinetic-pharmacodynamic modeling of the respiratory depressant effect of norbuprenorphine in rats

artículo científico publicado en 2007

Pharmacokinetics and Bioavailability of Inhaled Esketamine in Healthy Volunteers

artículo científico publicado en 2017

Pharmacokinetics of ketamine and its major metabolites norketamine, hydroxynorketamine, and dehydronorketamine: a model-based analysis

artículo científico publicado en 2020

Pharmacotherapy for pain: efficacy and safety issues examined by subgroup analyses

artículo científico

Pharmacovigilance: a review of opioid-induced respiratory depression in chronic pain patients.

artículo científico publicado en 2013

Plasticity in the brain: influence of bilateral carotid body resection (bCBR) on central CO2 sensitivity

artículo científico publicado en 2008

Plasticity of central chemoreceptors: effect of bilateral carotid body resection on central CO2 sensitivity

artículo científico publicado en 2007

Polymorphism of mu-opioid receptor gene (OPRM1:c.118A>G) does not protect against opioid-induced respiratory depression despite reduced analgesic response.

artículo científico publicado en 2005

Population pharmacokinetic-pharmacodynamic modeling of epidural anesthesia

artículo científico publicado en 2008

Population pharmacokinetic-pharmacodynamic modeling of ketamine-induced pain relief of chronic pain

artículo científico publicado en 2010

Population pharmacokinetics of morphine and morphine-6-glucuronide following rectal administration--a dose escalation study

artículo científico publicado en 2014

Population pharmacokinetics/pharmacodynamics of anesthetics

artículo científico publicado en 2005

Postoperative epidural analgesia after total knee arthroplasty with sufentanil 1 microg/ml combined with ropivacaine 0.2%, ropivacaine 0.125%, or levobupivacaine 0.125%: a randomized, double-blind comparison.

artículo científico publicado en 2007

Postoperative respiratory state assessment using the Integrated Pulmonary Index (IPI) and resultant nurse interventions in the post-anesthesia care unit: a randomized controlled trial

artículo científico publicado en 2020

Potent Opioid Analgesia without Respiratory Depression: Could It Be Possible?

artículo científico publicado en 2016

Predictive value of a diagnostic block in focal nerve injury with neuropathic pain when surgery is considered

scientific article published in PLoS ONE

Primum non nocere or how to resolve drug-induced respiratory depression

artículo científico publicado en 2013

Propofol reduces the distribution and clearance of midazolam

artículo científico publicado en 2010

Quantification of small fiber pathology in patients with sarcoidosis and chronic pain using cornea confocal microscopy and skin biopsies

artículo científico publicado en 2017

Randomized Controlled Trial on the Influence of Intraoperative Remifentanil versus Fentanyl on Acute and Chronic Pain after Cardiac Surgery

artículo científico publicado en 2017

Recent advances in neuromuscular block during anesthesia.

artículo científico publicado en 2018

Reduced postoperative pain using Nociception Level-guided fentanyl dosing during sevoflurane anaesthesia: a randomised controlled trial

scientific article published on 16 September 2020

Remifentanil versus fentanyl during cardiac surgery on the incidence of chronic thoracic pain (REFLECT): study protocol for a randomized controlled trial

artículo científico publicado en 2014

Respiratory Effects of the Nociceptin/Orphanin FQ Peptide and Opioid Receptor Agonist, Cebranopadol, in Healthy Human Volunteers

artículo científico publicado en 2017

Respiratory depression by tramadol in the cat: involvement of opioid receptors

artículo científico publicado en 2003

Respiratory depression with opioids

artículo científico publicado en 2007

Response surface modeling of remifentanil-propofol interaction on cardiorespiratory control and bispectral index

artículo científico publicado en 2003

Reversal of Partial Neuromuscular Block and the Ventilatory Response to Hypoxia: A Randomized Controlled Trial in Healthy Volunteers

scientific article published on 01 September 2019

S(+)-Ketamine analgesic drug dose

S(+)-ketamine effect on experimental pain and cardiac output: a population pharmacokinetic-pharmacodynamic modeling study in healthy volunteers

artículo científico publicado en 2009

Safety and efficacy of ARA 290 in sarcoidosis patients with symptoms of small fiber neuropathy: a randomized, double-blind pilot study

artículo científico publicado en 2012

Safety and efficacy of ketamine for pain relief

artículo científico publicado en 2016

Safety of sugammadex for reversal of neuromuscular block

artículo científico publicado en 2019

Sdhd and SDHD/H19 knockout mice do not develop paraganglioma or pheochromocytoma

artículo científico publicado en 2009

Sex-specific mediation of opioid-induced hyperalgesia by the melanocortin-1 receptor

artículo científico publicado en 2010

Sex-specific responses to opiates: animal and human studies

artículo científico publicado en 2008

Simultaneous measurement and integrated analysis of analgesia and respiration after an intravenous morphine infusion

artículo científico publicado en 2004

Spatial heterogeneity of the relation between resting-state connectivity and blood flow: an important consideration for pharmacological studies.

artículo científico publicado en 2012

Stochastic Pharmacokinetic-Pharmacodynamic Analysis of the Effect of Transdermal Buprenorphine on Electroencephalogram and Analgesia

artículo científico publicado en 2015

Study protocol for a randomised, double-blinded, placebo-controlled, clinical trial of S-ketamine for pain treatment in patients with chronic pancreatitis (RESET trial).

artículo científico publicado en 2015

Subjective Effects of Ethanol, Morphine, Δ(9)-Tetrahydrocannabinol, and Ketamine Following a Pharmacological Challenge Are Related to Functional Brain Connectivity.

artículo científico publicado en 2015

Sublingual sufentanil for postoperative pain relief: first clinical experiences.

artículo científico publicado en 2018

Tapentadol treatment results in long-term pain relief in patients with chronic low back pain and associates with reduced segmental sensitization

scientific article published on 01 November 2020

Targeting the innate repair receptor to treat neuropathy.

artículo científico publicado en 2016

The absorption profile of pregabalin in chronic pancreatitis

artículo científico publicado en 2012

The carbonic anhydrase inhibitors methazolamide and acetazolamide have different effects on the hypoxic ventilatory response in the anaesthetized cat

scientific article published on 04 May 2006

The dose-dependent effect of S(+)-ketamine on cardiac output in healthy volunteers and complex regional pain syndrome type 1 chronic pain patients

artículo científico publicado en 2012

The epidural "top-up": predictors of increase of sensory blockade

artículo científico publicado en 2002

The impact of "physiological correction" on functional connectivity analysis of pharmacological resting state fMRI.

artículo científico publicado en 2012

The influence of offset analgesia on the onset and offset of pain in patients with fibromyalgia

artículo científico publicado en 2015

The influence of remifentanil on the dynamic relationship between sevoflurane and surrogate anesthetic effect measures derived from the EEG.

artículo científico publicado en 2002

The interaction between propofol and clonidine for loss of consciousness

artículo científico publicado en 2002

The respiratory response to carbon dioxide in humans with unilateral and bilateral resections of the carotid bodies

artículo científico publicado en 2003

The use of a battery of pain models to detect analgesic properties of compounds: a two-part four-way crossover study.

artículo científico publicado en 2016

The use of surgical rating scales for the evaluation of surgical working conditions during laparoscopic surgery: a scoping review

article

The ventilatory response to CO2 of the peripheral and central chemoreflex loop before and after sustained hypoxia in man ⬇️

artículo científico publicado el 1 de octubre de 1992

The ventilatory response to hypoxia in mammals: mechanisms, measurement, and analysis

artículo científico publicado en 2010

Tolerance to opioid-induced respiratory depression in chronic high-dose opioid users: a model-based comparison with opioid-naïve individuals

scientific article published on 31 August 2020

Translation of random painful stimuli into numerical responses in fibromyalgia and perioperative patients.

artículo científico publicado en 2015

Translational PK-PD modeling in pain

artículo científico publicado en 2012

Two studies on reversal of opioid-induced respiratory depression by BK-channel blocker GAL021 in human volunteers

artículo científico publicado en 2014

Update of the Scientific Opinion on opium alkaloids in poppy seeds

artículo científico publicado en 2018

Using Akaike's information theoretic criterion in mixed-effects modeling of pharmacokinetic data: a simulation study

artículo científico publicado en 2013

Venlafaxine and oxycodone have different effects on spinal and supraspinal activity in man: a somatosensory evoked potential study.

artículo científico publicado en 2016

[Prevention of prolonged opioid use after surgery]

scientific article published on 16 August 2018

Lista de obras de

A Randomized Controlled Trial on the Effect of Tapentadol and Morphine on Conditioned Pain Modulation in Healthy Volunteers

A comparison of the central nervous system effects of alcohol at pseudo-steady state in Caucasian and expatriate Japanese healthy male volunteers

A pragmatic utility function to describe the risk-benefit composite of opioid and non-opioid analgesic medication

A randomised controlled trial on the efficacy and side-effect profile (nausea/vomiting/sedation) of morphine-6-glucuronide versus morphine for post-operative pain relief after major abdominal surgery

A randomized, double-blind, placebo-controlled pilot study of IV morphine-6-glucuronide for postoperative pain relief after knee replacement surgery

A retrospective study on persistent pain after childbirth in the Netherlands

ARA 290 for treatment of small fiber neuropathy in sarcoidosis.

ARA 290, a nonerythropoietic peptide engineered from erythropoietin, improves metabolic control and neuropathic symptoms in patients with type 2 diabetes.

ARA290, a peptide derived from the tertiary structure of erythropoietin, produces long-term relief of neuropathic pain: an experimental study in rats and β-common receptor knockout mice.

Ability of the nociception level, a multiparameter composite of autonomic signals, to detect noxious stimuli during propofol-remifentanil anesthesia

Absence of long-term analgesic effect from a short-term S-ketamine infusion on fibromyalgia pain: a randomized, prospective, double blind, active placebo-controlled trial

Acetazolamide improves cerebral oxygenation during exercise at high altitude

Acute and chronic fentanyl administration causes hyperalgesia independently of opioid receptor activity in mice

Alfentanil and placebo analgesia: no sex differences detected in models of experimental pain

An experimental randomized study on the analgesic effects of pharmaceutical-grade cannabis in chronic pain patients with fibromyalgia

An observational study on the effect of S+-ketamine on chronic pain versus experimental acute pain in Complex Regional Pain Syndrome type 1 patients.

Analgesic and Respiratory Depressant Effects of R-dihydroetorphine: A Pharmacokinetic-Pharmacodynamic Analysis in Healthy Male Volunteers

Analysis of cerebrospinal fluid inflammatory mediators in chronic complex regional pain syndrome related dystonia

Animal-to-human extrapolation of the pharmacokinetic and pharmacodynamic properties of buprenorphine

Antioxidants prevent blunting of hypoxic ventilatory response by low-dose halothane.

Antioxidants prevent depression of the acute hypoxic ventilatory response by subanaesthetic halothane in men.

Antioxidants reverse depression of the hypoxic ventilatory response by acetazolamide in man.

Antioxidants reverse reduction of the human hypoxic ventilatory response by subanesthetic isoflurane

Arterial Line Placement: Safety First

Arterial [H+] and the ventilatory response to hypoxia in humans: influence of acetazolamide-induced metabolic acidosis

Arterial and venous pharmacokinetics of morphine-6-glucuronide and impact of sample site on pharmacodynamic parameter estimates

Assessment of allodynia relief by tissue-protective molecules in a rat model of nerve injury-induced neuropathic pain

Assessment of middle cerebral artery diameter during hypocapnia and hypercapnia in humans using ultra-high-field MRI.

Averting Opioid-induced Respiratory Depression without Affecting Analgesia

Benefit and Risk Evaluation of Biased μ-Receptor Agonist Oliceridine versus Morphine

Benefit versus Severe Side Effects of Opioid Analgesia: Novel Utility Functions of Probability of Analgesia and Respiratory Depression.

Big brain, small world?

Bispectral index values and spectral edge frequency at different stages of physiologic sleep

Cannabis-opioid interaction in the treatment of fibromyalgia pain: an open-label, proof of concept study with randomization between treatment groups: cannabis, oxycodone or cannabis/oxycodone combination—the SPIRAL study

Carotid body tumors in humans caused by a mutation in the gene for succinate dehydrogenase D (SDHD).

Causes and consequences of the opioid epidemic in the Netherlands: a population-based cohort study

Cholinergic Chemotransmission and Anesthetic Drug Effects at the Carotid Bodies

Cibinetide Improves Corneal Nerve Fiber Abundance in Patients With Sarcoidosis-Associated Small Nerve Fiber Loss and Neuropathic Pain.

Circadian influences, low-dose isoflurane, and the ventilatory response to hypoxia

Combined Recirculatory-compartmental Population Pharmacokinetic Modeling of Arterial and Venous Plasma S(+) and R(-) Ketamine Concentrations

Comment on Rosenberg J, et al.: "Deep Neuromuscular Blockade Improves Laparoscopic Surgical Conditions: A Randomized, Controlled Study".

Comorbidities and the complexities of chronic pain.

Comparison of Two Different Analgesic Prescription Strategies and Healthcare Systems: Slovenia vs. the Netherlands

Cornea nerve fiber quantification and construction of phenotypes in patients with fibromyalgia.

Cornea nerve fibre state determines analgesic response to tapentadol in fibromyalgia patients without effective endogenous pain modulation

Corneal nerve fiber size adds utility to the diagnosis and assessment of therapeutic response in patients with small fiber neuropathy.

Deep Neuromuscular Block Improves Surgical Conditions during Bariatric Surgery and Reduces Postoperative Pain: A Randomized Double Blind Controlled Trial

Deep Neuromuscular Block and Surgical Conditions During Bariatric Surgery

Deep neuromuscular block does not improve surgical conditions in patients receiving sevoflurane anaesthesia for laparoscopic renal surgery

Developmental changes in morphine clearance across the entire paediatric age range are best described by a bodyweight-dependent exponent model.

Differences between opioids: pharmacological, experimental, clinical and economical perspectives

Differential effect of morphine and morphine-6-glucuronide on the control of breathing in the anesthetized cat.

Do sex differences exist in opioid analgesia? A systematic review and meta-analysis of human experimental and clinical studies

Does deep neuromuscular block affect pain after laparoscopic surgery?

Does nociception monitor-guided anesthesia affect opioid consumption? A systematic review of randomized controlled trials

Drug-induced liver injury following a repeated course of ketamine treatment for chronic pain in CRPS type 1 patients: a report of 3 cases

Early postoperative pain after laparoscopic donor nephrectomy predicts 30-day postoperative infectious complications: a pooled analysis of randomized controlled trials

Effect of Rifampicin on S-ketamine and S-norketamine Plasma Concentrations in Healthy Volunteers after Intravenous S-ketamine Administration ⬇️

Effect of deafferentation from spinal anesthesia on pain sensitivity and resting-state functional brain connectivity in healthy male volunteers.

Effect of ketamine on endogenous pain modulation in healthy volunteers.

Effect of subanesthetic ketamine on intrinsic functional brain connectivity: a placebo-controlled functional magnetic resonance imaging study in healthy male volunteers

Efficacy and safety of morphine-6-glucuronide (M6G) for postoperative pain relief: a randomized, double-blind study

Efficacy of profound versus moderate neuromuscular blockade in enhancing postoperative recovery after laparoscopic donor nephrectomy: A randomised controlled trial

Endogenous modulation of pain is visible in the brain

Endogenous pain modulation: from humans to animals and back

Epidural Blockade Affects the Pharmacokinetics of Propofol in Surgical Patients

Epidural and Non-epidural Analgesia in Patients Undergoing Open Pancreatectomy: a Retrospective Cohort Study

Erratum to: Quality of Recovery After Low-Pressure Laparoscopic Donor Nephrectomy Facilitated by Deep Neuromuscular Blockade: A Randomized Controlled Study

Evaluating Patient-Centered Outcomes in Clinical Trials of Procedural Sedation, Part 2 Safety: Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research Recommendations

Fentanyl utility function: a risk-benefit composite of pain relief and breathing responses

Frequent respiratory events in postoperative patients aged 60 years and above

From breathtaking to encapsulation: a novel approach to reverse respiratory depression from opioid overdosing

Functional biomarkers for the acute effects of alcohol on the central nervous system in healthy volunteers

Gender differences in morphine pharmacokinetics and dynamics.

Handheld Retinal Oximetry in Healthy Young Adults

Health-related quality of life in 975 patients with complex regional pain syndrome type 1.

Hospital variation in allogeneic transfusion and extended length of stay in primary elective hip and knee arthroplasty: a cross-sectional study

Hyperalgesia and Reduced Offset Analgesia During Spinal Anesthesia

Impact of high- versus low-dose neuromuscular blocking agent administration on unplanned 30-day readmission rates in retroperitoneal laparoscopic surgery.