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A Potent Tartrate Resistant Acid Phosphatase Inhibitor to Study the Function of TRAP in Alveolar Macrophages

artículo científico publicado en 2017

A cellular census of human lungs identifies novel cell states in health and in asthma

artículo científico publicado en 2019

A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK

artículo científico publicado en 2012

A genome-wide association study of chronic obstructive pulmonary disease in Hispanics

artículo científico publicado en 2015

A large lung gene expression study identifying fibulin-5 as a novel player in tissue repair in COPD.

artículo científico publicado en 2014

A pro-inflammatory role for the Frizzled-8 receptor in chronic bronchitis

artículo científico publicado en 2016

Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD.

artículo científico publicado en 2018

Alternative Splicing Is a Major Factor Shaping Transcriptome Diversity in Mild and Severe Chronic Obstructive Pulmonary Disease

artículo científico publicado en 2024

Atopy and Inhaled Corticosteroid Use Associate with Fewer IL-17+ Cells in Asthmatic Airways

artículo científico publicado en 2016

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

scientific article published on 01 June 2019

COPD-derived fibroblasts secrete higher levels of senescence-associated secretory phenotype proteins

scientific article published on 03 December 2020

Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution

scientific article published on 11 December 2019

Cigarette smoke-induced emphysema: A role for the B cell?

artículo científico publicado en 2006

Cigarette smoke-induced epithelial expression of WNT-5B: implications for COPD.

artículo científico publicado en 2016

Correction: Lung eQTLs to Help Reveal the Molecular Underpinnings of Asthma.

artículo científico publicado en 2012

Current Smoking is Associated with Decreased Expression of miR-335-5p in Parenchymal Lung Fibroblasts

artículo científico publicado en 2019

Current perspectives on the role of interleukin-1 signalling in the pathogenesis of asthma and COPD

artículo científico publicado en 2020

Defective Fibrillar Collagen Organization by Fibroblasts Contributes to Airway Remodeling in Asthma

artículo científico publicado en 2019

Differential effects of fluticasone on extracellular matrix production by airway and parenchymal fibroblasts in severe COPD.

artículo científico publicado en 2013

Differential lung tissue gene expression in males and females: implications for the susceptibility to develop COPD

scientific article published on 18 July 2019

Differential switching to IgG and IgA in active smoking COPD patients and healthy controls.

artículo científico publicado en 2012

Dissecting the genetics of chronic mucus hypersecretion in smokers with and without COPD.

artículo científico publicado en 2014

Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in COPD

artículo científico publicado en 2019

Effects of cigarette smoke extract on human airway smooth muscle cells in COPD.

artículo científico publicado en 2014

Epithelial-interleukin-1 inhibits collagen formation by airway fibroblasts: Implications for asthma

scientific article published on 26 May 2020

Fibulin-5 as a potential therapeutic target in COPD

From blood to lung tissue: effect of cigarette smoke on DNA methylation and lung function

article published in 2018

Functional variants regulating LGALS1 (Galectin 1) expression affect human susceptibility to influenza A(H7N9).

artículo científico publicado en 2015

Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction

artículo científico publicado en 2014

Genetic regulation of gene expression of MIF family members in lung tissue

artículo científico publicado en 2020

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

artículo científico publicado en 2017

Genome-wide association study on the FEV1/FVC ratio in never-smokers identifies HHIP and FAM13A.

artículo científico publicado en 2016

Genome-wide interaction study of gene-by-occupational exposures on respiratory symptoms

artículo científico publicado en 2018

Heme oxygenase-1 prevents smoke induced B-cell infiltrates: a role for regulatory T cells?

artículo científico publicado en 2008

Identification of Drug Candidates to Suppress Cigarette Smoke-induced Inflammation via cMap Analyses

artículo científico publicado en 2017

Identification of TMPRSS2 as a Susceptibility Gene for Severe 2009 Pandemic A(H1N1) Influenza and A(H7N9) Influenza.

artículo científico publicado en 2015

Identification of transforming growth factor-beta-regulated microRNAs and the microRNA-targetomes in primary lung fibroblasts

artículo científico publicado en 2017

Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD

artículo científico publicado en 2020

Increased levels of (class switched) memory B cells in peripheral blood of current smokers

artículo científico publicado en 2009

Induction of autoantibodies against lung matrix proteins and smoke-induced inflammation in mice

artículo científico publicado en 2010

Integrated proteogenomic approach identifying a protein signature of COPD and a new splice variant of SORBS1

scientific article published on 14 January 2020

Interleukin-1α drives the dysfunctional cross-talk of the airway epithelium and lung fibroblasts in COPD.

artículo científico publicado en 2016

Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population

artículo científico publicado en 2019

Link between increased cellular senescence and extracellular matrix changes in COPD

artículo científico publicado en 2020

Lung ageing and COPD: is there a role for ageing in abnormal tissue repair?

artículo científico publicado en 2017

Lung eQTLs to help reveal the molecular underpinnings of asthma

artículo científico publicado en 2012

Lung tissue gene-expression signature for the ageing lung in COPD.

artículo científico publicado en 2017

Marked TGF-β-regulated miRNA expression changes in both COPD and control lung fibroblasts

scientific article published on 03 December 2019

MiR-31-5p: A shared regulator of chronic mucus hypersecretion in asthma and chronic obstructive pulmonary disease

scientific article published on 23 October 2019

Mouse protocadherin-1 gene expression is regulated by cigarette smoke exposure in vivo.

artículo científico publicado en 2014

Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression

artículo científico publicado en 2017

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

artículo científico publicado en 2019

New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

scholarly article published 12 June 2018

Nitrogen Dioxide Exposure Attenuates Cigarette Smoke-Induced Cytokine Production in Mice

article

Novel Genes for Airway Wall Thickness Identified with Combined Genome-Wide Association and Expression Analyses

article

Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium

artículo científico publicado en 2020

Protective effect of club cell secretory protein (CC-16) on COPD risk and progression: a Mendelian randomisation study

artículo científico publicado en 2020

Proteogenomics: Key Driver for Clinical Discovery and Personalized Medicine

artículo científico publicado en 2016

RAGE and TLR4 differentially regulate airway hyperresponsiveness: implications for COPD

artículo científico publicado en 2020

Recent advances in chronic obstructive pulmonary disease pathogenesis: from disease mechanisms to precision medicine

artículo científico publicado en 2019

Responsiveness to Ipratropium Bromide in Male and Female Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease.

artículo científico publicado en 2017

Role of BAFF in pulmonary autoantibody responses induced by chronic cigarette smoke exposure in mice

artículo científico publicado en 2016

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

artículo científico publicado en 2015

Sulfatase modifying factor 1 (SUMF1) is associated with Chronic Obstructive Pulmonary Disease

artículo científico publicado en 2017

The Overlap of Lung Tissue Transcriptome of Smoke Exposed Mice with Human Smoking and COPD

scientific article published in Scientific Reports

The Translation from Risk Allele to Biological Function in Chronic Obstructive Pulmonary Disease. What's in It for FAM13A?

artículo científico publicado en 2016

The pharmacogenomics of inhaled corticosteroids and lung function decline in COPD

scientific article published on 04 December 2019

Total particulate matter concentration skews cigarette smoke's gene expression profile

artículo científico publicado en 2016

Unravelling the complexity of COPD by microRNAs: it's a small world after all.

artículo científico

Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction.

artículo científico publicado en 2014

miR-146a-5p plays an essential role in the aberrant epithelial-fibroblast cross-talk in COPD.

artículo científico publicado en 2017

miR-638 regulates gene expression networks associated with emphysematous lung destruction

artículo científico publicado en 2013

microRNA–mRNA regulatory networks underlying chronic mucus hypersecretion in COPD

artículo científico publicado en 2018