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A dual modulator of farnesoid X receptor and soluble epoxide hydrolase to counter non-alcoholic steatohepatitis

artículo científico

Binding Mode Characterization and Early in Vivo Evaluation of Fragment-Like Thiols as Inhibitors of the Virulence Factor LasB from Pseudomonas aeruginosa.

artículo científico publicado en 2018

Boosting Anti-Inflammatory Potency of Zafirlukast by Designed Polypharmacology

artículo científico publicado en 2018

Design, Synthesis, and Structure-Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5-Lipoxygenase

scientific article published on 12 October 2020

Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain

scientific article published on 17 September 2019

Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator

artículo científico publicado en 2024

Nonacidic Farnesoid X Receptor Modulators

artículo científico publicado en 2017

Opportunities and Challenges for Fatty Acid Mimetics in Drug Discovery.

artículo científico publicado en 2017

Polypharmacology by Design: A Medicinal Chemist's Perspective on Multitargeting Compounds

artículo científico publicado en 2018

Spirocyclic Scaffolds in Medicinal Chemistry

scientific article published on 31 December 2020

Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation

scientific article published on 15 February 2019

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