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A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation.

artículo científico publicado en 2016

A VGF-derived peptide attenuates development of type 2 diabetes via enhancement of islet β-cell survival and function.

artículo científico publicado en 2012

A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

artículo científico publicado en 2009

A futile metabolic cycle activated in adipocytes by antidiabetic agents

artículo científico publicado en 2002

A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase regulates glucose-stimulated insulin secretion

artículo científico publicado en 2006

Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy

artículo científico publicado en 2012

Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease

scientific journal article

Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease

scientific article published on 22 October 2009

Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance

artículo científico publicado en 2012

Adverse Effects of Fenofibrate in Mice Deficient in the Protein Quality Control Regulator, CHIP

article

Altered branched-chain α-keto acid metabolism is a feature of NAFLD in individuals with severe obesity

artículo científico publicado en 2022

An adenovirus vector for efficient RNA interference-mediated suppression of target genes in insulinoma cells and pancreatic islets of langerhans

artículo científico publicado en 2004

Analysis of serum metabolic profiles in women with endometrial cancer and controls in a population-based case-control study

artículo científico publicado en 2012

Association of Plasma Small-Molecule Intermediate Metabolites With Age and Body Mass Index Across Six Diverse Study Populations.

artículo científico publicado en 2016

Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events

artículo científico publicado en 2010

Associations of maternal BMI and insulin resistance with the maternal metabolome and newborn outcomes.

artículo científico publicado en 2016

BMI, RQ, diabetes, and sex affect the relationships between amino acids and clamp measures of insulin action in humans

artículo científico publicado en 2013

Baseline metabolomic profiles predict cardiovascular events in patients at risk for coronary artery disease

artículo científico publicado en 2012

Beta-cell specific ablation of sirtuin 4 does not affect nutrient-stimulated insulin secretion in mice

scientific article published on 31 August 2020

Biochemistry. A glucose-to-gene link

artículo científico publicado en 2009

Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells

artículo científico publicado en 2003

Biomedicine. Insulin resistance takes a trip through the ER.

artículo científico publicado en 2004

Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism.

artículo científico publicado en 2014

Branched chain amino acids are novel biomarkers for discrimination of metabolic wellness

artículo científico publicado en 2013

Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export

artículo científico publicado en 2016

Branched-chain amino acids alter neurobehavioral function in rats

artículo científico publicado en 2012

Branched-chain amino acids in disease

scientific article published on 01 February 2019

Branching out for detection of type 2 diabetes

artículo científico publicado en 2011

CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-α-Gabpa and stress-induced adaptive responses via NF-κB-cMYC

artículo científico publicado en 2015

Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice.

artículo científico publicado en 2014

Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial

artículo científico publicado en 2012

Cardiomyocyte glucagon receptor signaling modulates outcomes in mice with experimental myocardial infarction

artículo científico publicado en 2014

Cardiomyocyte-Specific Human Bcl2-Associated Anthanogene 3 P209L Expression Induces Mitochondrial Fragmentation, Bcl2-Associated Anthanogene 3 Haploinsufficiency, and Activates p38 Signaling

artículo científico publicado en 2016

Cardiovascular Metabolomics

artículo científico publicado en 2018

Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure

artículo científico publicado en 2016

Cell lines derived from pancreatic islets

artículo científico publicado en 2004

Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis

artículo científico publicado en 2007

Cholinergic augmentation of insulin release requires ankyrin-B.

artículo científico publicado en 2010

Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice

artículo científico publicado en 2013

Compartmentalized acyl-CoA metabolism in skeletal muscle regulates systemic glucose homeostasis

artículo científico publicado en 2014

Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion

artículo científico publicado en 2006

Contamination with E1A-positive wild-type adenovirus accounts for species-specific stimulation of islet cell proliferation by CCK: a cautionary note.

artículo científico publicado en 2010

Control of voltage-gated potassium channel Kv2.2 expression by pyruvate-isocitrate cycling regulates glucose-stimulated insulin secretion.

artículo científico publicado en 2013

Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3

scientific journal article

Coordinated regulatory variation associated with gestational hyperglycaemia regulates expression of the novel hexokinase HKDC1

artículo científico publicado en 2015

Cord Blood Metabolomics: Association With Newborn Anthropometrics and C-Peptide Across Ancestries

scientific article published on 01 October 2019

Correction: Genetic Networks of Liver Metabolism Revealed by Integration of Metabolic and Transcriptional Profiling

artículo científico publicado en 2008

Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing

artículo científico publicado en 2019

Daily Variation of Serum Acylcarnitines and Amino Acids

artículo científico publicado en 2012

Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival

artículo científico publicado en 2017

Deletion of CaMKK2 from the liver lowers blood glucose and improves whole-body glucose tolerance in the mouse

artículo científico publicado en 2012

Diabetes: The good in fat.

artículo científico publicado en 2014

Dietary Patterns among Asian Indians Living in the United States Have Distinct Metabolomic Profiles That Are Associated with Cardiometabolic Risk

artículo científico publicado en 2018

Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins

scientific article published on 01 October 2019

Dietary branched-chain amino acid restriction alters fuel selection and reduces triglyceride stores in hearts of Zucker fatty rats

artículo científico publicado en 2019

Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss

artículo científico publicado en 2011

Diminished acyl-CoA synthetase isoform 4 activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion

artículo científico publicado en 2013

Discrete and complementary mechanisms of protection of beta-cells against cytokine-induced and oxidative damage achieved by bcl-2 overexpression and a cytokine selection strategy

artículo científico publicado en 2003

Disrupted Maturation of the Microbiota and Metabolome among Extremely Preterm Infants with Postnatal Growth Failure.

artículo científico publicado en 2019

Dissecting the in vivo metabolic potential of two human gut acetogens

artículo científico publicado en 2010

Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver

article

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

artículo científico publicado en 2017

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

artículo científico publicado en 2018

Effect of Progressive Weight Loss on Lactate Metabolism: A Randomized Controlled Trial.

artículo científico publicado en 2018

Effect of Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding on branched-chain amino acid metabolism.

artículo científico publicado en 2013

Effect of caloric restriction with and without exercise on metabolic intermediates in nonobese men and women

artículo científico publicado en 2010

Effect of heparin administration on metabolomic profiles in samples obtained during cardiac catheterization

artículo científico publicado en 2011

Effects of HIV infection on the metabolic and hormonal status of children with severe acute malnutrition

artículo científico publicado en 2014

Effects of a gut pathobiont in a gnotobiotic mouse model of childhood undernutrition

artículo científico publicado en 2016

Effects of microbiota-directed foods in gnotobiotic animals and undernourished children

scientific article published on 01 July 2019

Effects of the kinase inhibitor sorafenib on heart, muscle, liver and plasma metabolism in vivo using non-targeted metabolomics analysis.

artículo científico publicado en 2017

Efficient gene delivery to pancreatic islets with ultrasonic microbubble destruction technology

artículo científico publicado en 2006

Energetics and metabolism in the failing heart: important but poorly understood

artículo científico publicado en 2010

Enhanced GLUT4-Dependent Glucose Transport Relieves Nutrient Stress in Obese Mice Through Changes in Lipid and Amino Acid Metabolism

artículo científico publicado en 2016

Erratum. Maternal BMI and Glycemia Impact the Fetal Metabolome. Diabetes Care 2017;40:902-910.

artículo científico publicado en 2018

Exercise-induced changes in metabolic intermediates, hormones, and inflammatory markers associated with improvements in insulin sensitivity.

artículo científico publicado en 2010

Fasting-induced hepatic production of DHEA is regulated by PGC-1alpha, ERRalpha, and HNF4alpha

scientific journal article

Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice

artículo científico publicado en 2014

Fatty acid oxidation and insulin action: when less is more

artículo científico publicado en 2008

Fenofibrate Induced Cardiac Fibrosis in Mice Deficient in the Protein Quality Control Regulator, CHIP

FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site

artículo científico publicado en 2006

Functional genomics of the beta-cell: short-chain 3-hydroxyacyl-coenzyme A dehydrogenase regulates insulin secretion independent of K+ currents.

artículo científico publicado en 2006

Galphaz negatively regulates insulin secretion and glucose clearance

artículo científico publicado en 2007

Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling

artículo científico publicado en 2008

Getting biological about the genetics of diabetes

artículo científico publicado en 2010

Glucose metabolism as a target of histone deacetylase inhibitors.

artículo científico publicado en 2008

Glycogen-targeting subunits and glucokinase differentially affect pathways of glycogen metabolism and their regulation in hepatocytes

artículo científico publicado en 2001

Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children

artículo científico publicado en 2016

Gut microbiota from twins discordant for obesity modulate metabolism in mice

artículo científico publicado en 2013

HIF-1 Alpha Regulates the Response of Primary Sarcomas to Radiation Therapy through a Cell Autonomous Mechanism.

artículo científico publicado en 2015

Hepatic Expression of a Targeting Subunit of Protein Phosphatase-1 in Streptozotocin-diabetic Rats Reverses Hyperglycemia and Hyperphagia Despite Depressed Glucokinase Expression

artículo científico publicado el 15 de abril de 2003

Hepatic SRC-1 activity orchestrates transcriptional circuitries of amino acid pathways with potential relevance for human metabolic pathogenesis

artículo científico publicado en 2014

Hepatic acyl-CoA:diacylglcyerol acyltransferase (DGAT) overexpression, diacylglycerol, and insulin sensitivity

artículo científico publicado el 23 de agosto de 2011

Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance

artículo científico publicado en 2004

Hepatic mTORC1 Opposes Impaired Insulin Action to Control Mitochondrial Metabolism in Obesity

artículo científico publicado en 2016

Hepatic overexpression of glycerol-sn-3-phosphate acyltransferase 1 in rats causes insulin resistance

artículo científico publicado en 2007

High heritability of metabolomic profiles in families burdened with premature cardiovascular disease

artículo científico publicado en 2009

Human amylin proteotoxicity impairs protein biosynthesis, and alters major cellular signaling pathways in the heart, brain and liver of humanized diabetic rat model in vivo.

artículo científico publicado en 2016

Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP.

artículo científico publicado en 2005

Identification of a small molecule that stimulates human β-cell proliferation and insulin secretion, and protects against cytotoxic stress in rat insulinoma cells

artículo científico publicado en 2020

Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans

artículo científico publicado en 2015

Improvement in insulin resistance after gastric bypass surgery is correlated with a decline in plasma 2-hydroxybutyric acid

scientific article published on 17 April 2018

Improving human β-cell maturation in vitro

artículo científico publicado en 2019

Increased insulin sensitivity in mice lacking collectrin, a downstream target of HNF-1alpha

scientific article published on 26 February 2009

Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle

artículo científico publicado en 2007

Increasing fructose 2,6-bisphosphate overcomes hepatic insulin resistance of type 2 diabetes

artículo científico publicado el 1 de enero de 2002

Induction of miR-132 and miR-212 Expression by Glucagon-Like Peptide 1 (GLP-1) in Rodent and Human Pancreatic β-Cells

artículo científico publicado en 2015

Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77.

artículo científico publicado en 2009

Integrated metabolomics and genomics: systems approaches to biomarkers and mechanisms of cardiovascular disease

artículo científico publicado en 2015

Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.

artículo científico publicado en 2017

Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells

artículo científico publicado en 2015

Isolation of a mycoplasma-specific binding peptide from an unbiased phage-displayed peptide library

artículo científico publicado en 2005

John Denis McGarry, PhD: A Remembrance of a Master Metabolic Physiologist

scientific article published on 01 July 2018

Kruppel-like factor 15 is required for the cardiac adaptive response to fasting.

artículo científico publicado en 2018

Leptin therapy in insulin-deficient type I diabetes

artículo científico publicado en 2010

Lower brain-derived neurotrophic factor in patients with prader-willi syndrome compared to obese and lean control subjects

artículo científico publicado en 2010

Marginal vitamin B-6 deficiency decreases plasma (n-3) and (n-6) PUFA concentrations in healthy men and women

artículo científico publicado en 2012

Maternal metabolites during pregnancy are associated with newborn outcomes and hyperinsulinaemia across ancestries

scientific article published on 27 November 2018

Mechanical unloading promotes myocardial energy recovery in human heart failure

artículo científico publicado en 2014

Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes

artículo científico publicado en 2005

Mechanisms of disease:Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes

artículo científico publicado en 2008

Metabolic Networks and Metabolites Underlie Associations Between Maternal Glucose During Pregnancy and Newborn Size at Birth.

artículo científico publicado en 2016

Metabolic profiles predict adverse events after coronary artery bypass grafting

artículo científico publicado en 2012

Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation

artículo científico publicado en 2014

Metabolism: A is for adipokine

artículo científico publicado en 2005

Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Failure With Preserved Versus Reduced Ejection Fraction: Evidence for Shared Metabolic Impairments in Clinical Heart Failure

artículo científico publicado en 2016

Metabolomic Profiling Reveals a Role for Caspase-2 in Lipoapoptosis

artículo científico publicado el 3 de abril de 2013

Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis

artículo científico publicado en 2015

Metabolomic analysis reveals extended metabolic consequences of marginal vitamin B-6 deficiency in healthy human subjects

artículo científico publicado en 2013

Metabolomic profile associated with insulin resistance and conversion to diabetes in the Insulin Resistance Atherosclerosis Study

artículo científico publicado en 2014

Metabolomic profiling for the identification of novel biomarkers and mechanisms related to common cardiovascular diseases: form and function

artículo científico publicado en 2012

Metabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion.

artículo científico publicado en 2009

Metabolomics applied to diabetes research: moving from information to knowledge

artículo científico publicado en 2009

Metabolomics applied to islet nutrient sensing mechanisms

artículo científico publicado en 2017

Metabolomics reveals broad-scale metabolic perturbations in hyperglycemic mothers during pregnancy

scientific article published on 29 August 2013

Mig-6 plays a critical role in the regulation of cholesterol homeostasis and bile acid synthesis.

artículo científico publicado en 2012

Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues

artículo científico publicado en 2002

Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance

artículo científico publicado en 2008

Mixture model normalization for non-targeted gas chromatography/mass spectrometry metabolomics data

artículo científico publicado en 2017

Moderate dietary vitamin B-6 restriction raises plasma glycine and cystathionine concentrations while minimally affecting the rates of glycine turnover and glycine cleavage in healthy men and women

artículo científico publicado en 2009

MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet

artículo científico publicado en 2015

Multi-Omic Profiling Reveals the Opposing Forces of Excess Dietary Sugar and Fat on Liver Mitochondria Protein Acetylation and Succinylation

scholarly article published 10 February 2018

Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet.

artículo científico publicado en 2015

Muscle-Liver Trafficking of BCAA-Derived Nitrogen Underlies Obesity-Related Glycine Depletion

artículo científico publicado en 2020

Near-roadway air pollution exposure and altered fatty acid oxidation among adolescents and young adults - The interplay with obesity

scientific article published on 22 June 2019

Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis

artículo científico publicado en 2009

Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors

scientific journal article

Non-Targeted Metabolomics Analysis of Golden Retriever Muscular Dystrophy-Affected Muscles Reveals Alterations in Arginine and Proline Metabolism, and Elevations in Glutamic and Oleic Acid In Vivo

artículo científico publicado en 2017

Non-targeted metabolomics analysis of cardiac Muscle Ring Finger-1 (MuRF1), MuRF2, and MuRF3 in vivo reveals novel and redundant metabolic changes.

artículo científico publicado en 2014

Non-targeted metabolomics of Brg1/Brm double-mutant cardiomyocytes reveals a novel role for SWI/SNF complexes in metabolic homeostasis

artículo científico publicado en 2015

OR07-1 Cord Blood Metabolomics: Association with Newborn Anthropometrics and C-Peptide across Ancestries

Obesity and lipid stress inhibit carnitine acetyltransferase activity

artículo científico publicado en 2014

Obesity-related derangements in metabolic regulation

artículo científico publicado en 2006

Overexpression of pre-pro-cholecystokinin stimulates beta-cell proliferation in mouse and human islets with retention of islet function

artículo científico publicado en 2008

PGC-1beta in the regulation of hepatic glucose and energy metabolism

scientific journal article

Pathogenesis of A⁻β⁺ ketosis-prone diabetes

artículo científico publicado en 2012

Pdx-1 activates islet α- and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2.

artículo científico publicado en 2013

Peptide-mediated targeting of the islets of Langerhans

artículo científico publicado en 2005

Perinatal western-type diet and associated gestational weight gain alter postpartum maternal mood.

artículo científico publicado en 2017

Peripheral blood metabolite profiles associated with new onset atrial fibrillation

artículo científico publicado en 2019

Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency

artículo científico publicado en 2005

Physiological mechanisms of sustained fumagillin-induced weight loss.

artículo científico publicado en 2018

Plasma acylcarnitines are associated with physical performance in elderly men

artículo científico publicado en 2011

Plasma acylcarnitines are associated with pulmonary hypertension

artículo científico publicado en 2017

Postprandial Metabolite Profiles Reveal Differential Nutrient Handling After Bariatric Surgery Compared With Matched Caloric Restriction

artículo científico publicado el 1 de abril de 2014

Prior Dietary Practices and Connections to a Human Gut Microbial Metacommunity Alter Responses to Diet Interventions

artículo científico publicado en 2016

Pro- and antiapoptotic proteins regulate apoptosis but do not protect against cytokine-mediated cytotoxicity in rat islets and beta-cell lines

artículo científico publicado en 2006

Proteomic Profiling Reveals Adaptive Responses to Surgical Myocardial Ischemia-Reperfusion in Hibernating Arctic Ground Squirrels Compared to Rats

artículo científico publicado en 2016

Race and sex differences in small-molecule metabolites and metabolic hormones in overweight and obese adults

artículo científico publicado en 2013

Rapid and weight-independent improvement of glucose tolerance induced by a peptide designed to elicit apoptosis in adipose tissue endothelium.

artículo científico publicado en 2012

Recommendations for Improving Identification and Quantification in Non-Targeted, GC-MS-Based Metabolomic Profiling of Human Plasma

artículo científico publicado en 2017

Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion

artículo científico publicado en 2020

Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation

artículo científico publicado en 2019

Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability

artículo científico publicado el 16 de febrero de 2011

Regulation of skeletal muscle oxidative capacity and insulin signaling by the mitochondrial rhomboid protease PARL.

artículo científico publicado en 2010

Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women

artículo científico publicado en 2009

Remodeling of the Acetylproteome by SIRT3 Manipulation Fails to Affect Insulin Secretion or β Cell Metabolism in the Absence of Overnutrition

artículo científico publicado en 2018

Research Resource: Roles for Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) in Systems Metabolism

artículo científico publicado en 2016

Research resource: tissue- and pathway-specific metabolomic profiles of the steroid receptor coactivator (SRC) family

artículo científico publicado en 2013

Restoration of hepatic glucokinase expression corrects hepatic glucose flux and normalizes plasma glucose in zucker diabetic fatty rats

artículo científico publicado en 2008

Reversal of Diet-induced Glucose Intolerance by Hepatic Expression of a Variant Glycogen-targeting Subunit of Protein Phosphatase-1

artículo científico publicado el 13 de noviembre de 2001

SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome

artículo científico publicado en 2011

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

artículo científico publicado en 2010

SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks

scientific journal article

SRC-2 coactivator deficiency decreases functional reserve in response to pressure overload of mouse heart

artículo científico publicado en 2012

Severe acute malnutrition in childhood: hormonal and metabolic status at presentation, response to treatment, and predictors of mortality

artículo científico publicado en 2014

Sialylated Milk Oligosaccharides Promote Microbiota-Dependent Growth in Models of Infant Undernutrition.

artículo científico publicado en 2016

Sildenafil Treatment in Heart Failure With Preserved Ejection Fraction: Targeted Metabolomic Profiling in the RELAX Trial

artículo científico publicado en 2017

Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent islets

artículo científico publicado en 2008

Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation

artículo científico publicado en 2013

Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization

artículo científico publicado en 2012

Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1

artículo científico publicado en 2008

Stimulus/secretion coupling factors in glucose-stimulated insulin secretion: insights gained from a multidisciplinary approach

artículo científico publicado en 2002

Suppression of beta cell energy metabolism and insulin release by PGC-1alpha

artículo científico publicado en 2003

Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor

artículo científico publicado en 2012

TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism

artículo científico publicado en 2006

Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose

artículo científico publicado en 2018

The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase.

artículo científico publicado en 2018

The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells

artículo científico publicado en 2005

The Prohormone VGF Regulates β Cell Function via Insulin Secretory Granule Biogenesis.

artículo científico publicado en 2017

The Role of Voltage-Gated Potassium Channels Kv2.1 and Kv2.2 in the Regulation of Insulin and Somatostatin Release from Pancreatic Islets

artículo científico publicado el 16 de noviembre de 2012

The STEDMAN project: biophysical, biochemical and metabolic effects of a behavioral weight loss intervention during weight loss, maintenance, and regain

artículo científico publicado en 2009

The Study of the Effects of Diet on Metabolism and Nutrition (STEDMAN) weight loss project: Rationale and design

artículo científico publicado en 2005

The coactivator SRC-1 is an essential coordinator of hepatic glucose production.

artículo científico publicado en 2010

The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins

artículo científico publicado en 2011

The liver--a potential new player in islet regeneration?

artículo científico publicado en 2009

The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion

artículo científico publicado en 2010

The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion

artículo científico publicado en 2006

The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance

artículo científico publicado en 2012

The promoter for the gene encoding the catalytic subunit of rat glucose-6-phosphatase contains two distinct glucose-responsive regions

artículo científico publicado en 2006

The role of AMPK and mTOR in nutrient sensing in pancreatic beta-cells

artículo científico publicado en 2007

The ubiquitin ligase MuRF1 regulates PPARα activity in the heart by enhancing nuclear export via monoubiquitination

artículo científico publicado en 2015

Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy

artículo científico publicado el 11 de junio de 2012

Trefoil factor 3 stimulates human and rodent pancreatic islet beta-cell replication with retention of function

artículo científico publicado en 2008

Understanding of basic mechanisms of beta-cell function and survival: prelude to new diabetes therapies

artículo científico publicado en 2004

Validation of the association between a branched chain amino acid metabolite profile and extremes of coronary artery disease in patients referred for cardiac catheterization

artículo científico publicado en 2013