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A Comprehensive Assessment of Demographic, Environmental and Host Genetic Associations with Gut Microbiome Diversity in Healthy Individuals

A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals

scientific article published on 13 September 2019

A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes

artículo científico publicado en 2012

A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease

artículo científico publicado en 2008

A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation

artículo científico publicado en 2005

An in vitro diagnostic certified point of care single nucleotide test for IL28B polymorphisms

artículo científico publicado en 2017

Antigen Cross-Priming of Cell-Associated Proteins is Enhanced by Macroautophagy within the Antigen Donor Cell.

artículo científico publicado en 2012

Antigen persistence is required for dendritic cell licensing and CD8+ T cell cross-priming

artículo científico

Apolipoprotein H expression is associated with IL28B genotype and viral clearance in hepatitis C virus infection

artículo científico publicado en 2014

Apoptotic cells deliver processed antigen to dendritic cells for cross-presentation

artículo científico publicado en 2005

Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation

artículo científico publicado en 2020

Associations between consumption of dietary fibers and the risk of cardiovascular diseases, cancers, type 2 diabetes, and mortality in the prospective NutriNet-Santé cohort

scientific article published on 05 May 2020

Associations between untargeted plasma metabolomic signatures and gut microbiota composition in the <i>Milieu Intérieur</i> population of healthy adults

artículo científico publicado en 2020

Associations between usual diet and gut microbiota composition: results from the Milieu Intérieur cross-sectional study

scientific article published on 01 May 2019

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Automated flow cytometric analysis across large numbers of samples and cell types

artículo científico publicado en 2015

Autophagy diminishes the early interferon-β response to influenza A virus resulting in differential expression of interferon-stimulated genes.

artículo científico publicado en 2018

Autophagy during viral infections: a double-edge sword

scientific article published on 01 October 2013

BCG-mediated bladder cancer immunotherapy: identifying determinants of treatment response using a calibrated mathematical model

artículo científico publicado en 2013

Bacillus Calmette-Guérin strain differences have an impact on clinical outcome in bladder cancer immunotherapy

artículo científico publicado en 2014

Basophils from allergic patients are neither hyper-responsive to activation signals nor hypo-responsive to inhibition signals

artículo científico publicado en 2018

Biology and pathogenesis of chikungunya virus ⬇️

artículo científico publicado en 2010

Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients

artículo científico publicado en 2015

CXCL10 antagonism and plasma sDPPIV correlate with increasing liver disease in chronic HCV genotype 4 infected patients ⬇️

artículo científico publicado el 7 de mayo de 2013

CXCR3/CXCL10 Axis Shapes Tissue Distribution of Memory Phenotype CD8+ T Cells in Nonimmunized Mice.

artículo científico publicado en 2017

Characterization of reemerging chikungunya virus

artículo científico publicado en 2007

Chikungunya virus superinfection exclusion is mediated by a block in viral replication and does not rely on non-structural protein 2

artículo científico publicado en 2020

Chikungunya virus-associated long-term arthralgia: a 36-month prospective longitudinal study

artículo científico publicado en 2013

Chikungunya virus-induced autophagy delays caspase-dependent cell death

artículo científico publicado en 2012

Chikungunya-induced cell death is limited by ER and oxidative stress-induced autophagy

artículo científico publicado en 2012

Circulating plasmacytoid dendritic cells in acutely infected patients with hepatitis C virus genotype 4 are normal in number and phenotype.

artículo científico publicado en 2010

Comment on "NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis".

artículo científico publicado en 2016

Correction: Chikungunya Virus-associated Long-term Arthralgia: A 36-month Prospective Longitudinal Study

scholarly article published in PLoS Neglected Tropical Diseases

Correction: Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity

artículo científico publicado en 2018

Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity

artículo científico publicado en 2017

Cutting Edge: A dual role for type I IFNs during polyinosinic-polycytidylic acid-induced NK cell activation.

artículo científico publicado en 2011

Cutting edge: independent roles for IRF-3 and IRF-7 in hematopoietic and nonhematopoietic cells during host response to Chikungunya infection

artículo científico publicado en 2012

Deconvolution of the Response to Bacillus Calmette-Guérin Reveals NF-κB-Induced Cytokines As Autocrine Mediators of Innate Immunity

artículo científico publicado en 2017

Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN- / on antigen cross-presentation

artículo científico publicado en 2006

Detection of interferon alpha protein reveals differential levels and cellular sources in disease.

artículo científico publicado en 2017

Development and clinical validation of the Genedrive point-of-care test for qualitative detection of hepatitis C virus

article

Development of a Bead-Based Multiplex Assay for the Analysis of the Serological Response against the Six Pathogens HAV, HBV, HCV, CMV, T. gondii, and H. pylori

artículo científico publicado en 2017

Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy

artículo científico publicado en 2015

Dissecting T cell contraction in vivo using a genetically encoded reporter of apoptosis.

artículo científico publicado en 2012

Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges

artículo científico publicado en 2017

Dying to Replicate: The Orchestration of the Viral Life Cycle, Cell Death Pathways, and Immunity ⬇️

artículo científico publicado el 28 de octubre de 2011

Dynamic Changes of Post-Translationally Modified Forms of CXCL10 and Soluble DPP4 in HCV Subjects Receiving Interferon-Free Therapy

artículo científico publicado en 2015

Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset

artículo científico publicado en 2016

Enumeration of human antigen-specific naive CD8+ T cells reveals conserved precursor frequencies

artículo científico publicado en 2010

Evidence for an antagonist form of the chemokine CXCL10 in patients chronically infected with HCV ⬇️

artículo científico publicado el 22 de diciembre de 2010

Frequent transient hepatitis C viremia without seroconversion among healthcare workers in Cairo, Egypt

artículo científico publicado en 2013

Functional analysis via standardized whole-blood stimulation systems defines the boundaries of a healthy immune response to complex stimuli

artículo científico publicado en 2014

Gamma c cytokines condition the progressive differentiation of CD4+ T cells

artículo científico publicado en 2007

Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations

artículo científico publicado en 2016

Genetic factors and age are the strongest predictors of humoral immune responses to common pathogens and vaccines

article

Genetic variation associated with thyroid autoimmunity shapes the systemic immune response to PD-1 checkpoint blockade ⬇️

artículo científico publicado en 2021

Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration

artículo científico publicado en 2018

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

Gut microbiome stability and dynamics in healthy donors and patients with non-gastrointestinal cancers

artículo científico publicado en 2021

Harnessing naturally occurring tumor immunity: a clinical vaccine trial in prostate cancer

artículo científico publicado en 2010

Hepatitis E Virus-Induced Primary Cutaneous CD30(+) T cell Lymphoproliferative Disorder

artículo científico publicado en 2017

Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines

article

Human thymopoiesis is influenced by a common genetic variant within the TCRA-TCRD locus

artículo científico publicado en 2018

IL-2 is required for the activation of memory CD8+ T cells via antigen cross-presentation

artículo científico publicado en 2006

ISG15 is critical in the control of Chikungunya virus infection independent of UbE1L mediated conjugation

artículo científico publicado en 2011

Identification of a novel neuropathogenic Theiler's murine encephalomyelitis virus

artículo científico publicado en 2011

Immune profiling enables stratification of patients with active TB disease or M. tuberculosis infection

artículo científico publicado en 2020

Immune response against dying tumor cells

artículo científico publicado en 2004

Immunization route dictates cross-priming efficiency and impacts the optimal timing of adjuvant delivery ⬇️

artículo científico publicado el 8 de diciembre de 2011

Immunosuppressive signature of cutaneous Mycobacterium ulcerans infection in the peripheral blood of patients with buruli ulcer disease

artículo científico publicado en 2009

Impact of IL28B, APOH and ITPA Polymorphisms on Efficacy and Safety of TVR- or BOC-Based Triple Therapy in Treatment-Experienced HCV-1 Patients with Compensated Cirrhosis from the ANRS CO20-CUPIC Study

artículo científico publicado en 2015

In silico tools for accurate HLA and KIR inference from clinical sequencing data empower immunogenetics on individual-patient and population scales

scientific article published on 17 September 2020

In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity

artículo científico publicado en 2015

Inhibition of DPP4 activity in humans establishes its in vivo role in CXCL10 post-translational modification: prospective placebo-controlled clinical studies

artículo científico publicado en 2016

Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses

artículo científico publicado en 2016

Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway

artículo científico publicado en 2015

Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth

artículo científico publicado en 2019

Innate sensing of HIV-infected cells

artículo científico publicado en 2011

Interferon induced protein 10 remains a useful biomarker of treatment failure in patients stratified for the interleukin-28B rs12979860 Haplotype

artículo científico publicado en 2011

Interplay of DDP4 and IP-10 as a Potential Mechanism for Cell Recruitment to Tuberculosis Lesions

artículo científico publicado en 2018

Litchi–associated Acute Encephalitis in Children, Northern Vietnam, 2004–2009 ⬇️

artículo científico publicado el 1 de noviembre de 2012

Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes

artículo científico publicado en 2005

Local immune response to injection of Plasmodium sporozoites into the skin

artículo científico publicado en 2014

Low DPP4 expression and activity in multiple sclerosis

artículo científico publicado en 2013

Macrophages Subvert Adaptive Immunity to Urinary Tract Infection

artículo científico publicado en 2015

Mathematical model of tumor immunotherapy for bladder carcinoma identifies the limitations of the innate immune response ⬇️

artículo científico publicado el 1 de enero de 2012

Mechanisms of immune-related adverse events associated with immune checkpoint blockade: using germline genetics to develop a personalized approach

artículo científico publicado en 2019

Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency

artículo científico

Molecular analyte profiling of the early events and tissue conditioning following intravesical bacillus calmette-guerin therapy in patients with superficial bladder cancer

artículo científico publicado en 2009

Multimarker risk stratification approach at multiple sclerosis onset.

artículo científico publicado en 2017

Muscle resident macrophages control the immune cell reaction in a mouse model of notexin-induced myoinjury

scientific article published on 01 January 2010

Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors

artículo científico publicado en 2018

New tools for pathology: a user's review of a highly multiplexed method for in situ analysis of protein and RNA expression in tissue

artículo científico publicado en 2019

Normal functional capacity in circulating myeloid and plasmacytoid dendritic cells in patients with chronic hepatitis C

artículo científico publicado en 2005

Plasma apolipoprotein H limits HCV replication and associates with response to NS3 protease inhibitors-based therapy

artículo científico publicado en 2015

Plasma biomarkers discriminate clinical forms of multiple sclerosis

artículo científico publicado en 2015

Plasmacytoid dendritic cells control dengue and Chikungunya virus infections via IRF7-regulated interferon responses.

artículo científico publicado en 2018

Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients

artículo científico publicado en 2007

Plasmacytoid dendritic cells move down on the list of suspects: in search of the immune pathogenesis of chronic hepatitis C.

artículo científico publicado en 2008

Polygenic risk for skin autoimmunity impacts immune checkpoint blockade in bladder cancer

scientific article published on 19 May 2020

Preexisting BCG-specific T cells improve intravesical immunotherapy for bladder cancer.

artículo científico publicado en 2012

Presence of functional dendritic cells in patients chronically infected with hepatitis C virus ⬇️

artículo científico publicado el 2 de octubre de 2003

Protein biomarkers discriminate Leishmania major-infected and non-infected individuals in areas endemic for cutaneous leishmaniasis

artículo científico publicado en 2016

Publisher Correction: Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors

scientific article published on 01 June 2018

RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8⁺ T cells.

artículo científico publicado en 2015

RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity

scientific article published on 01 August 2019

Selection of high-avidity CD8 T cells correlates with control of hepatitis C virus infection

artículo científico publicado en 2008

Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone

artículo científico publicado en 2007

Semi-automated and standardized cytometric procedures for multi-panel and multi-parametric whole blood immunophenotyping

artículo científico publicado en 2015

Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection

artículo científico publicado en 2019

Signal 0 for guided priming of CTLs: NKT cells do it too.

scientific article published on April 2010

Simultaneous assessment of autophagy and apoptosis using multispectral imaging cytometry.

artículo científico publicado en 2011

Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses.

artículo científico publicado en 2016

Standardized whole blood stimulation improves immunomonitoring of induced immune responses in multi-center study

artículo científico publicado en 2017

Study of the Humoral Immune Response towards HCV Genotype 4 Using a Bead-Based Multiplex Serological Assay

Subcapsular sinus macrophages promote NK cell accumulation and activation in response to lymph-borne viral particles

artículo científico publicado en 2012

Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing

artículo científico publicado en 2015

Systemic DPP4 activity is reduced during primary HIV-1 infection and is associated with intestinal RORC+ CD4+ cell levels: a surrogate marker candidate of HIV-induced intestinal damage

artículo científico publicado en 2018

T-cell biomarkers for diagnosis of tuberculosis: candidate evaluation by a simple whole blood assay for clinical translation

artículo científico publicado en 2018

The ABCs of viral hepatitis that define biomarker signatures of acute viral hepatitis

artículo científico publicado en 2014

The Milieu Intérieur study - an integrative approach for study of human immunological variance

artículo científico publicado en 2015

Tracking Antigen-Specific CD8+ T Cells Using MHC Class I Multimers ⬇️

artículo científico publicado el 1 de enero de 2013

Transposable element expression in tumors is associated with immune infiltration and increased antigenicity

scientific article published on 19 November 2019

Truncated CXCL10 is associated with failure to achieve spontaneous clearance of acute hepatitis C infection

artículo científico publicado en 2014

Type I IFN controls chikungunya virus via its action on nonhematopoietic cells

artículo científico publicado en 2010

Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia

artículo científico publicado en 2013

Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents

artículo científico publicado en 2017

Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice

artículo científico publicado en 2017

Visualizing the functional diversification of CD8+ T cell responses in lymph nodes

artículo científico publicado en 2010

Visualizing the innate and adaptive immune responses underlying allograft rejection by two-photon microscopy

artículo científico publicado en 2011

Widespread mitochondrial depletion via mitophagy does not compromise necroptosis

artículo científico publicado en 2013

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

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