Lista de obras -

A Fab-Selective Immunoglobulin-Binding Domain from Streptococcal Protein G with Improved Half-Life Extension Properties

artículo científico publicado en 2015

A fast and effective determination of the biodistribution and subcellular localization of fluorescent immunoliposomes in freshly excised animal organs

artículo científico publicado en 2017

A fusogenic dengue virus-derived peptide enhances antitumor efficacy of an antibody-ribonuclease fusion protein targeting the EGF receptor

artículo científico publicado en 2014

A novel expression and purification system for the production of enzymatic and biologically active human granzyme B.

artículo científico publicado en 2011

Activatable bispecific liposomes bearing fibroblast activation protein directed single chain fragment/Trastuzumab deliver encapsulated cargo into the nuclei of tumor cells and the tumor microenvironment simultaneously

artículo científico publicado en 2017

Alternative antibody formats.

artículo científico publicado en 2010

An EGF receptor targeting Ranpirnase-diabody fusion protein mediates potent antitumour activity in vitro and in vivo

artículo científico publicado en 2014

An antibody fusion protein for cancer immunotherapy mimicking IL-15 trans-presentation at the tumor site

artículo científico publicado en 2012

An optimized antibody-single-chain TRAIL fusion protein for cancer therapy.

artículo científico publicado en 2016

Antagonistic TNF receptor one-specific antibody (ATROSAB): receptor binding and in vitro bioactivity

artículo científico publicado en 2013

Antagonists of TNF action: clinical experience and new developments

artículo científico

Antibody phage display technologies with special reference to angiogenesis

artículo científico publicado en 2005

Antibody-cytokine fusion proteins

artículo científico publicado en 2012

Antitumor Activity of a Mesenchymal Stem Cell Line Stably Secreting a Tumor-Targeted TNF-Related Apoptosis-Inducing Ligand Fusion Protein

artículo científico publicado en 2017

Biodistribution of a bispecific single-chain diabody and its half-life extended derivatives

scientific article published on 23 July 2009

Bispecific antibodies for cancer immunotherapy: Current perspectives

artículo científico publicado en 2010

Bispecific single-chain diabody-immunoliposomes targeting endoglin (CD105) and fibroblast activation protein (FAP) simultaneously

artículo científico publicado en 2015

Bispecific single-chain diabody-mediated killing of endoglin-positive endothelial cells by cytotoxic T lymphocytes

artículo científico

CAR-J cells for antibody discovery and lead optimization of TCR-like immunoglobulins

artículo científico publicado en 2020

Cell selection and characterization of a novel human endothelial cell specific nanobody

artículo científico publicado en 2009

Dataset on FAP-induced emergence of spontaneous metastases and on the preparation of activatable FAP-targeting immunoliposomes to detect the metastases

artículo científico publicado en 2016

Design, selection and optimization of an anti-TRAIL-R2/anti-CD3 bispecific antibody able to educate T cells to recognize and destroy cancer cells

artículo científico publicado en 2018

Diabody-Ig: a novel platform for the generation of multivalent and multispecific antibody molecules

scientific article published on 03 May 2019

Dual targeting strategies with bispecific antibodies

artículo científico publicado en 2012

Duokines: a novel class of dual-acting co-stimulatory molecules acting in cis or trans

artículo científico publicado en 2018

Essential protective role of tumor necrosis factor receptor 2 in neurodegeneration

artículo científico publicado en 2016

Evaluating combinations of costimulatory antibody-ligand fusion proteins for targeted cancer immunotherapy

artículo científico publicado en 2013

Expression and purification of recombinant antibody formats and antibody fusion proteins

artículo científico publicado en 2014

Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potential

artículo científico publicado en 2014

Genetic delivery of an immunoRNase by an oncolytic adenovirus enhances anticancer activity

artículo científico publicado en 2014

Half-life extended biotherapeutics

artículo científico publicado en 2016

Half-life extension of a single-chain diabody by fusion to domain B of staphylococcal protein A.

artículo científico publicado en 2012

Humanization of a mouse monoclonal antibody directed against a cell surface-exposed epitope of membrane-associated heat shock protein 70 (Hsp70).

artículo científico publicado en 2010

Immuno-LipoTRAIL: Targeted delivery of TRAIL-functionalized liposomal nanoparticles

artículo científico publicado en 2014

Immunoliposomes for cancer therapy.

artículo científico publicado en 2006

Improved monovalent TNF receptor 1-selective inhibitor with novel heterodimerizing Fc

scientific article published on 31 March 2019

In vivo near-infrared fluorescence imaging of FAP-expressing tumors with activatable FAP-targeted, single-chain Fv-immunoliposomes

artículo científico publicado en 2014

Inhibition of HER3 activation and tumor growth with a human antibody binding to a conserved epitope formed by domain III and IV.

artículo científico publicado en 2017

Inhibition of cell proliferation and induction of apoptosis by novel tetravalent peptides inhibiting DNA binding of E2F.

artículo científico publicado en 2003

Intrabodies as therapeutic agents

artículo científico publicado en 2004

Isolation from phage display libraries of lysine-deficient human epidermal growth factor variants for directional conjugation as targeting ligands

artículo científico publicado en 2003

Isolation of endothelial cell-specific human antibodies from a novel fully synthetic scFv library

artículo científico publicado en 2004

Monovalent TNF receptor 1-selective antibody with improved affinity and neutralizing activity

scientific article published on 02 October 2018

Murine endoglin-specific single-chain Fv fragments for the analysis of vascular targeting strategies in mice

artículo científico publicado en 2008

Novel RGD lipopeptides for the targeting of liposomes to integrin-expressing endothelial and melanoma cells

artículo científico publicado en 2004

Novel strategies to mimic transmembrane tumor necrosis factor-dependent activation of tumor necrosis factor receptor 2.

artículo científico publicado en 2017

Pharmacokinetic properties of IgG and various Fc fusion proteins in mice

artículo científico publicado en 2015

Phenocopy--a strategy to qualify chemical compounds during hit-to-lead and/or lead optimization

artículo científico publicado en 2010

Potential of activatable FAP-targeting immunoliposomes in intraoperative imaging of spontaneous metastases

artículo científico publicado en 2016

Recombinant bispecific antibodies for cancer therapy

artículo científico publicado en 2005

Recombinant bispecific antibodies for cellular cancer immunotherapy

artículo científico publicado en 2007

Recombinant bispecific antibodies for the targeting of adenoviruses to CEA-expressing tumour cells: a comparative analysis of bacterially expressed single-chain diabody and tandem scFv

artículo científico publicado en 2004

Specific gene delivery to liver sinusoidal and artery endothelial cells

artículo científico publicado en 2013

Strategies for extended serum half-life of protein therapeutics

artículo científico publicado en 2011

Strategies to extend plasma half-lives of recombinant antibodies

artículo científico publicado en 2009

Tetravalent antibody-scTRAIL fusion proteins with improved properties

artículo científico publicado en 2014

Tumor-antigen-binding bispecific antibodies for cancer treatment

artículo científico publicado en 2014

Lista de obras de

A Fab-Selective Immunoglobulin-Binding Domain from Streptococcal Protein G with Improved Half-Life Extension Properties

A fast and effective determination of the biodistribution and subcellular localization of fluorescent immunoliposomes in freshly excised animal organs

A fusogenic dengue virus-derived peptide enhances antitumor efficacy of an antibody-ribonuclease fusion protein targeting the EGF receptor

A novel expression and purification system for the production of enzymatic and biologically active human granzyme B.

Activatable bispecific liposomes bearing fibroblast activation protein directed single chain fragment/Trastuzumab deliver encapsulated cargo into the nuclei of tumor cells and the tumor microenvironment simultaneously

Alternative antibody formats.

An EGF receptor targeting Ranpirnase-diabody fusion protein mediates potent antitumour activity in vitro and in vivo

An antibody fusion protein for cancer immunotherapy mimicking IL-15 trans-presentation at the tumor site

An optimized antibody-single-chain TRAIL fusion protein for cancer therapy.

Antagonistic TNF receptor one-specific antibody (ATROSAB): receptor binding and in vitro bioactivity

Antagonists of TNF action: clinical experience and new developments

Antibody phage display technologies with special reference to angiogenesis

Antibody-cytokine fusion proteins

Antitumor Activity of a Mesenchymal Stem Cell Line Stably Secreting a Tumor-Targeted TNF-Related Apoptosis-Inducing Ligand Fusion Protein

Biodistribution of a bispecific single-chain diabody and its half-life extended derivatives

Bispecific antibodies for cancer immunotherapy: Current perspectives

Bispecific single-chain diabody-immunoliposomes targeting endoglin (CD105) and fibroblast activation protein (FAP) simultaneously

Bispecific single-chain diabody-mediated killing of endoglin-positive endothelial cells by cytotoxic T lymphocytes

CAR-J cells for antibody discovery and lead optimization of TCR-like immunoglobulins

Cell selection and characterization of a novel human endothelial cell specific nanobody

Dataset on FAP-induced emergence of spontaneous metastases and on the preparation of activatable FAP-targeting immunoliposomes to detect the metastases

Design, selection and optimization of an anti-TRAIL-R2/anti-CD3 bispecific antibody able to educate T cells to recognize and destroy cancer cells

Diabody-Ig: a novel platform for the generation of multivalent and multispecific antibody molecules

Dual targeting strategies with bispecific antibodies

Duokines: a novel class of dual-acting co-stimulatory molecules acting in cis or trans

Essential protective role of tumor necrosis factor receptor 2 in neurodegeneration

Evaluating combinations of costimulatory antibody-ligand fusion proteins for targeted cancer immunotherapy

Expression and purification of recombinant antibody formats and antibody fusion proteins

Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potential

Genetic delivery of an immunoRNase by an oncolytic adenovirus enhances anticancer activity

Half-life extended biotherapeutics

Half-life extension of a single-chain diabody by fusion to domain B of staphylococcal protein A.

Humanization of a mouse monoclonal antibody directed against a cell surface-exposed epitope of membrane-associated heat shock protein 70 (Hsp70).

Immuno-LipoTRAIL: Targeted delivery of TRAIL-functionalized liposomal nanoparticles

Immunoliposomes for cancer therapy.

Improved monovalent TNF receptor 1-selective inhibitor with novel heterodimerizing Fc

In vivo near-infrared fluorescence imaging of FAP-expressing tumors with activatable FAP-targeted, single-chain Fv-immunoliposomes

Inhibition of HER3 activation and tumor growth with a human antibody binding to a conserved epitope formed by domain III and IV.

Inhibition of cell proliferation and induction of apoptosis by novel tetravalent peptides inhibiting DNA binding of E2F.

Intrabodies as therapeutic agents

Isolation from phage display libraries of lysine-deficient human epidermal growth factor variants for directional conjugation as targeting ligands

Isolation of endothelial cell-specific human antibodies from a novel fully synthetic scFv library

Monovalent TNF receptor 1-selective antibody with improved affinity and neutralizing activity

Murine endoglin-specific single-chain Fv fragments for the analysis of vascular targeting strategies in mice

Novel RGD lipopeptides for the targeting of liposomes to integrin-expressing endothelial and melanoma cells

Novel strategies to mimic transmembrane tumor necrosis factor-dependent activation of tumor necrosis factor receptor 2.

Pharmacokinetic properties of IgG and various Fc fusion proteins in mice

Phenocopy--a strategy to qualify chemical compounds during hit-to-lead and/or lead optimization

Potential of activatable FAP-targeting immunoliposomes in intraoperative imaging of spontaneous metastases

Recombinant bispecific antibodies for cancer therapy

Recombinant bispecific antibodies for cellular cancer immunotherapy

Recombinant bispecific antibodies for the targeting of adenoviruses to CEA-expressing tumour cells: a comparative analysis of bacterially expressed single-chain diabody and tandem scFv

Specific gene delivery to liver sinusoidal and artery endothelial cells

Strategies for extended serum half-life of protein therapeutics

Strategies to extend plasma half-lives of recombinant antibodies

Tetravalent antibody-scTRAIL fusion proteins with improved properties

Tumor-antigen-binding bispecific antibodies for cancer treatment