Lista de obras -

Analysis of oncogenic activities of protein kinase D1 in head and neck squamous cell carcinoma

Antitumor mechanisms of targeting the PDK1 pathway in head and neck cancer

artículo científico publicado en 2012

Bortezomib up-regulates activated signal transducer and activator of transcription-3 and synergizes with inhibitors of signal transducer and activator of transcription-3 to promote head and neck squamous cell carcinoma cell death

artículo científico publicado en 2009

Caspase-8 mutations in head and neck cancer confer resistance to death receptor-mediated apoptosis and enhance migration, invasion, and tumor growth

artículo científico publicado en 2014

Crystallization and preliminary X-ray analysis of cyclophilin from Leishmania donovani

artículo científico publicado en 2002

First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy.

artículo científico publicado en 2012

Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3

scientific article published on 16 September 2009

HCS campaign to identify selective inhibitors of IL-6-induced STAT3 pathway activation in head and neck cancer cell lines

artículo científico publicado en 2015

High Content Imaging Assays for IL-6-Induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines

artículo científico publicado en 2018

High-content pSTAT3/1 imaging assays to screen for selective inhibitors of STAT3 pathway activation in head and neck cancer cell lines

artículo científico publicado en 2013

Increased Expression of HER2, HER3, and HER2:HER3 Heterodimers in HPV-Positive HNSCC Using a Novel Proximity-Based Assay: Implications for Targeted Therapies

artículo científico publicado en 2015

JAK kinase inhibition abrogates STAT3 activation and head and neck squamous cell carcinoma tumor growth.

artículo científico publicado en 2015

Lack of toxicity of a STAT3 decoy oligonucleotide.

artículo científico publicado en 2008

Mechanism of action of selective inhibitors of IL-6 induced STAT3 pathway in head and neck cancer cell lines

artículo científico publicado en 2017

Nucleic acid-based approaches to STAT inhibition

artículo científico publicado en 2012

Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors

artículo científico publicado en 2016

Orthotopic expression of human 15-lipoxygenase (LO)-1 in the dorsolateral prostate of normal wild-type C57BL/6 mouse causes PIN-like lesions.

artículo científico publicado en 2006

PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response

artículo científico publicado en 2015

Phase 1 study of EGFR-antisense DNA, cetuximab, and radiotherapy in head and neck cancer with preclinical correlatives

artículo científico publicado en 2018

Polyunsaturated fatty acid metabolizing 15-Lipoxygenase-1 (15-LO-1) expression in normal and tumorigenic human bladder tissues

artículo científico publicado en 2008

Prevention of Carcinogen-Induced Oral Cancer by Sulforaphane

artículo científico publicado en 2016

Randomized, placebo-controlled window trial of EGFR, Src, or combined blockade in head and neck cancer

artículo científico publicado en 2017

STAT3 as a Chemoprevention Target in Carcinogen-Induced Head and Neck Squamous Cell Carcinoma

artículo científico publicado en 2016

STAT3 oligonucleotide inhibits tumor angiogenesis in preclinical models of squamous cell carcinoma

artículo científico publicado en 2014

Systemic administration of a cyclic signal transducer and activator of transcription 3 (STAT3) decoy oligonucleotide inhibits tumor growth without inducing toxicological effects

artículo científico publicado en 2014

Targeting Stat3 abrogates EGFR inhibitor resistance in cancer.

artículo científico publicado en 2012

The Jigsaw Puzzle Model: Search for Conformational Specificity in Protein Interiors ⬇️

artículo científico publicado el 10 de octubre de 2003

Toxicity, pharmacokinetics and metabolism of a novel inhibitor of IL-6-induced STAT3 activation

artículo científico publicado en 2016

Ultrasound Targeted Microbubble Destruction-Mediated Delivery of a Transcription Factor Decoy Inhibits STAT3 Signaling and Tumor Growth

artículo científico publicado en 2015

Utility of 3'-[(18)F]fluoro-3'-deoxythymidine as a PET tracer to monitor response to gene therapy in a xenograft model of head and neck carcinoma.

artículo científico publicado en 2013

Lista de obras de

Analysis of oncogenic activities of protein kinase D1 in head and neck squamous cell carcinoma

Antitumor mechanisms of targeting the PDK1 pathway in head and neck cancer

Bortezomib up-regulates activated signal transducer and activator of transcription-3 and synergizes with inhibitors of signal transducer and activator of transcription-3 to promote head and neck squamous cell carcinoma cell death

Caspase-8 mutations in head and neck cancer confer resistance to death receptor-mediated apoptosis and enhance migration, invasion, and tumor growth

Crystallization and preliminary X-ray analysis of cyclophilin from Leishmania donovani

First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy.

Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3

HCS campaign to identify selective inhibitors of IL-6-induced STAT3 pathway activation in head and neck cancer cell lines

High Content Imaging Assays for IL-6-Induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines

High-content pSTAT3/1 imaging assays to screen for selective inhibitors of STAT3 pathway activation in head and neck cancer cell lines

Increased Expression of HER2, HER3, and HER2:HER3 Heterodimers in HPV-Positive HNSCC Using a Novel Proximity-Based Assay: Implications for Targeted Therapies

JAK kinase inhibition abrogates STAT3 activation and head and neck squamous cell carcinoma tumor growth.

Lack of toxicity of a STAT3 decoy oligonucleotide.

Mechanism of action of selective inhibitors of IL-6 induced STAT3 pathway in head and neck cancer cell lines

Nucleic acid-based approaches to STAT inhibition

Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors

Orthotopic expression of human 15-lipoxygenase (LO)-1 in the dorsolateral prostate of normal wild-type C57BL/6 mouse causes PIN-like lesions.

PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response

Phase 1 study of EGFR-antisense DNA, cetuximab, and radiotherapy in head and neck cancer with preclinical correlatives

Polyunsaturated fatty acid metabolizing 15-Lipoxygenase-1 (15-LO-1) expression in normal and tumorigenic human bladder tissues

Prevention of Carcinogen-Induced Oral Cancer by Sulforaphane

Randomized, placebo-controlled window trial of EGFR, Src, or combined blockade in head and neck cancer

STAT3 as a Chemoprevention Target in Carcinogen-Induced Head and Neck Squamous Cell Carcinoma

STAT3 oligonucleotide inhibits tumor angiogenesis in preclinical models of squamous cell carcinoma

Systemic administration of a cyclic signal transducer and activator of transcription 3 (STAT3) decoy oligonucleotide inhibits tumor growth without inducing toxicological effects

Targeting Stat3 abrogates EGFR inhibitor resistance in cancer.

The Jigsaw Puzzle Model: Search for Conformational Specificity in Protein Interiors ⬇️

Toxicity, pharmacokinetics and metabolism of a novel inhibitor of IL-6-induced STAT3 activation

Ultrasound Targeted Microbubble Destruction-Mediated Delivery of a Transcription Factor Decoy Inhibits STAT3 Signaling and Tumor Growth

Utility of 3'-[(18)F]fluoro-3'-deoxythymidine as a PET tracer to monitor response to gene therapy in a xenograft model of head and neck carcinoma.