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"Nomen not est omen": the (pro)renin receptor and receptor-mediated endocytosis in the proximal tubule-a new (pro)renin-independent role forATP6ap2

artículo científico publicado en 2021

(Pro)renin receptor (ATP6AP2) depletion arrests As4.1 cells in the G0/G1 phase thereby increasing formation of primary cilia

artículo científico publicado en 2017

A new transgenic rat model overexpressing the angiotensin II type 2 receptor provides evidence for inhibition of cell proliferation in the outer adrenal cortex

artículo científico publicado en 2012

A renin transcript lacking exon 1 encodes for a non-secretory intracellular renin that increases aldosterone production in transgenic rats

scientific article published on August 2008

ATP6AP2 over-expression causes morphological alterations in the hippocampus and in hippocampus-related behaviour.

artículo científico publicado en 2018

Adrenal Renin Expression and its Role inren-2 Transgenic Rats TGR(mREN2)27

artículo científico publicado el 1 de junio de 1998

Amiloride lowers arterial pressure in cyp1a1ren-2 transgenic rats without affecting renal vascular function

artículo científico publicado el 1 de noviembre de 2010

An Alternative Promoter in Intron1 of the Renin Gene is Regulated by Glucose Starvation via Serum Response Factor

artículo científico publicado en 2017

An alternative renin isoform is cardioprotective by modulating mitochondrial metabolism.

artículo científico publicado en 2018

An alternative transcript of the rat renin gene can result in a truncated prorenin that is transported into adrenal mitochondria

scientific article published on 01 February 1999

Angiotensin II-dependent hypertension causes reversible changes in the platelet proteome

artículo científico publicado en 2011

Angiotensin dependent and angiotensin independent protective effects of renin-b in H9c2 cells after anoxia

artículo científico publicado en 2020

Anti-necrotic and cardioprotective effects of a cytosolic renin isoform under ischemia-related conditions

artículo científico publicado en 2015

Association of plasma aldosterone with the metabolic syndrome in two German populations

artículo científico publicado en 2011

Changes of AT(2) receptor levels in the rat adrenal cortex and medulla induced by bilateral nephrectomy and its modulation by circulating ANG II

scientific article published on 01 May 2001

Chronic low-dose isotretinoin treatment limits renal damage in subtotally nephrectomized rats

artículo científico publicado en 2008

Cytosolic renin is targeted to mitochondria and induces apoptosis in H9c2 rat cardiomyoblasts

artículo científico publicado en 2008

Dose-dependent titration of prorenin and blood pressure in Cyp1a1ren-2 transgenic rats: absence of prorenin-induced glomerulosclerosis

artículo científico publicado en 2008

Effects of all-trans retinoic acid on renin-angiotensin system in rats with experimental nephritis

artículo científico publicado en 2001

Elevated aldosterone and blood pressure in a mouse model of familial hyperaldosteronism with ClC-2 mutation

artículo científico publicado en 2019

Elevated blood pressure and heart rate in human renin receptor transgenic rats.

artículo científico publicado en 2006

Enhanced Ca2+ signaling, mild primary aldosteronism, and hypertension in a familial hyperaldosteronism mouse model (Cacna1hM1560V/+)

artículo científico publicado en 2021

Expression of the mouse ren-2 gene in the small intestine is regulated by food intake

article

Functional significance of prorenin internalization in the rat heart

artículo científico publicado en 2002

Functions of the (pro)renin receptor (Atp6ap2) at molecular and system levels: pathological implications in hypertension, renal and brain development, inflammation, and fibrosis

artículo científico publicado en 2021

Intracellular sorting of renin: cell type specific differences and their consequences

artículo científico publicado en 2002

Isolation of Pure Mitochondria from Rat Kidneys and Western Blot of Mitochondrial Respiratory Chain Complexes

scholarly article

Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism

artículo científico publicado en 2009

Local renin-angiotensin systems in the adrenal gland

artículo científico

Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism

scientific journal article

Molecular changes in the early phase of renin-dependent cardiac hypertrophy in hypertensive cyp1a1ren-2 transgenic rats

artículo científico publicado el 11 de octubre de 2012

Non-secretory renin reduces oxidative stress and increases cardiomyoblast survival during glucose and oxygen deprivation

scientific article published on 11 February 2020

Ontogenetic regulation of mouse Ren-2d renin gene in transgenic hypertensive rats, TGR(mREN2)27

article

Overexpression of Renin-B Induces Warburg-like Effects That Are Associated with Increased AKT/mTOR Signaling

artículo científico publicado en 2022

Overexpression of Transcripts Coding for Renin-b but Not for Renin-a Reduce Oxidative Stress and Increase Cardiomyoblast Survival under Starvation Conditions

artículo científico publicado en 2021

Presence of renin within intramitochondrial dense bodies of the rat adrenal cortex

artículo científico publicado en 1996

Regression of cardiac hypertrophy in cyp1a1ren‐2 transgenic rats

artículo científico publicado el 19 de abril de 2012

Renin-1 Is Essential for Normal Renal Juxtaglomerular Cell Granulation and Macula Densa Morphology

artículo científico publicado el 18 de julio de 1997

Role of tissue renin in the pathophysiology of hypertension in TGR(mREN2)27 rats

artículo científico publicado en 1992

Secretory and cytosolic (pro)renin in kidney, heart, and adrenal gland

artículo científico publicado en 2008

Specific regulation of StAR expression in the rat adrenal zona glomerulosa. An in situ hybridization study

artículo científico publicado en 1998

StAR expression and the long-term aldosterone response to high-potassium diet in Wistar-Kyoto and spontaneously hypertensive rats

scientific journal article

Targeted inactivation of the Ren-2 gene in mice

scientific article published on 01 December 1996

The (pro)renin receptor / ATP6ap2 is expressed in the murine hippocampus by adult and newly generated neurons.

artículo científico publicado en 2013

The (pro)renin receptor and its interaction partners.

artículo científico publicado en 2017

The Wnt adaptor protein ATP6AP2 regulates multiple stages of adult hippocampal neurogenesis.

artículo científico publicado en 2015

The angiotensin II type 2 receptors protect renal tubule mitochondria in early stages of diabetes mellitus

artículo científico publicado en 2018

The renin-angiotensin system as a primary cause of polyarteritis nodosa in rats

artículo científico publicado en 2009

Time-based analysis of silver-stained proteins in acrylamide gels

artículo científico publicado en 2006

Transgenic rats carrying the mouse renin gene--morphological characterization of a low-renin hypertension model

artículo científico publicado el 1 de enero de 1992

Transgenic rats: new animal models in hypertension research. Invited lecture

artículo científico publicado en 1991