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Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease

artículo científico publicado en 2015

Experimental evidence for the age dependence of tau protein spread in the brain

scientific article published on 26 June 2019

Human tau increases amyloid β plaque size but not amyloid β-mediated synapse loss in a novel mouse model of Alzheimer's disease

artículo científico publicado en 2016

LRP1 is a master regulator of tau uptake and spread

scientific article published on 01 April 2020

Neurofibrillary tangle-bearing neurons are functionally integrated in cortical circuits in vivo

artículo científico publicado en 2013

Neurofibrillary tangles remain functionally integrated in cortical networks

Non-Fibrillar Oligomeric Amyloid-β within Synapses

artículo científico publicado en 2016

Propagation of tau pathology in Alzheimer's disease: identification of novel therapeutic targets

artículo científico publicado en 2013

Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity

artículo científico publicado en 2015

Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer's disease

artículo científico publicado en 2017

Tau causes synapse loss without disrupting calcium homeostasis in the rTg4510 model of tauopathy

artículo científico publicado en 2013

Tau pathology does not affect experience-driven single-neuron and network-wide Arc/Arg3.1 responses

artículo científico publicado en 2014

Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology

artículo científico publicado en 2013

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