Lista de obras -

A CD8+ T cell immune evasion protein specific to Epstein-Barr virus and its close relatives in Old World primates

artículo científico publicado en 2007

A bridge crosses the active-site canyon of the Epstein-Barr virus nuclease with DNase and RNase activities

artículo científico publicado en 2009

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

artículo científico publicado en 2014

Adenovirus-specific CD4+ T cell clones recognizing endogenous antigen inhibit viral replication in vitro through cognate interaction

Alternative Ii-independent antigen-processing pathway in leukemic blasts involves TAP-dependent peptide loading of HLA class II complexes ⬇️

artículo científico publicado el 5 de septiembre de 2010

An alternative model for type I interferon induction downstream of human TLR2

scientific article published on 12 August 2020

Balancing STING in antimicrobial defense and autoinflammation

artículo científico publicado en 2020

CD200 receptor controls sex-specific TLR7 responses to viral infection

artículo científico publicado en 2012

Cellular immunity against human papillomavirus associated cervical cancer

Chemical Tools for Studying TLR Signaling Dynamics

artículo científico publicado en 2017

Conditionally Controlling Human TLR2 Activity via Trans-Cyclooctene Caged Ligands

artículo científico publicado en 2020

Cowpox virus protein CPXV012 eludes CTLs by blocking ATP binding to TAP.

artículo científico publicado en 2014

EBV BILF1 evolved to downregulate cell surface display of a wide range of HLA class I molecules through their cytoplasmic tail

artículo científico publicado en 2013

EBV MicroRNA BART16 Suppresses Type I IFN Signaling.

artículo científico publicado en 2017

EBV lytic-phase protein BGLF5 contributes to TLR9 downregulation during productive infection.

artículo científico publicado en 2010

EBV protein BNLF2a exploits host tail-anchored protein integration machinery to inhibit TAP.

artículo científico publicado en 2011

Epstein-Barr virus evasion of CD8(+) and CD4(+) T cell immunity via concerted actions of multiple gene products.

scientific article published on 25 October 2008

Epstein-Barr virus gp42 is posttranslationally modified to produce soluble gp42 that mediates HLA class II immune evasion.

artículo científico publicado en 2005

Epstein-Barr virus isolates retain their capacity to evade T cell immunity through BNLF2a despite extensive sequence variation

artículo científico publicado en 2011

Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling

artículo científico publicado en 2014

Evaluation of viral interference with MHC class I-restricted antigen processing and presentation using a flow cytometry-based approach

artículo científico publicado en 2013

Exploiting human herpesvirus immune evasion for therapeutic gain: potential and pitfalls ⬇️

artículo científico publicado el 8 de febrero de 2011

Herpesvirus interference with major histocompatibility complex class II-restricted T-cell activation

artículo científico publicado en 2006

Hiding lipid presentation: viral interference with CD1d-restricted invariant natural killer T (iNKT) cell activation

artículo científico publicado en 2012

Host shutoff during productive Epstein-Barr virus infection is mediated by BGLF5 and may contribute to immune evasion

artículo científico publicado en 2007

Human B cells fail to secrete type I interferons upon cytoplasmic DNA exposure

artículo científico publicado en 2017

Human cytomegalovirus-encoded US2 differentially affects surface expression of MHC class I locus products and targets membrane-bound, but not soluble HLA-G1 for degradation

artículo científico publicado en 2003

Immune Evasion by Epstein-Barr Virus

artículo científico

Impaired transporter associated with antigen processing-dependent peptide transport during productive EBV infection

artículo científico publicado en 2005

Inflammasomes and viruses: cellular defence versus viral offence

artículo científico publicado en 2012

Inhibition of mouse TAP by immune evasion molecules encoded by non-murine herpesviruses

artículo científico publicado en 2011

Interference with T cell receptor–HLA-DR interactions by Epstein–Barr virus gp42 results in reduced T helper cell recognition ⬇️

artículo científico publicado el 22 de septiembre de 2003

Manipulation of the immune response by Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus: consequences for tumor development

artículo científico publicado en 2008

Silencing the shutoff protein of Epstein-Barr virus in productively infected B cells points to (innate) targets for immune evasion

artículo científico publicado en 2014

Specific targeting of the EBV lytic phase protein BNLF2a to the transporter associated with antigen processing results in impairment of HLA class I-restricted antigen presentation

artículo científico publicado en 2009

Stage-specific inhibition of MHC class I presentation by the Epstein-Barr virus BNLF2a protein during virus lytic cycle

artículo científico publicado en 2009

Structural and functional analysis of the TAP-inhibiting UL49.5 proteins of varicelloviruses.

artículo científico publicado en 2011

TAP-inhibiting proteins US6, ICP47 and UL49.5 differentially affect minor and major histocompatibility antigen-specific recognition by cytotoxic T lymphocytes

artículo científico publicado en 2007

The "Bridge" in the Epstein-Barr virus alkaline exonuclease protein BGLF5 contributes to shutoff activity during productive infection

artículo científico publicado en 2012

The DNase of gammaherpesviruses impairs recognition by virus-specific CD8+ T cells through an additional host shutoff function

artículo científico publicado en 2007

The Epstein-Barr Virus Glycoprotein gp150 Forms an Immune-Evasive Glycan Shield at the Surface of Infected Cells

artículo científico publicado en 2016

The Epstein-Barr virus G-protein-coupled receptor contributes to immune evasion by targeting MHC class I molecules for degradation

artículo científico publicado en 2009

The capacity of UL49.5 proteins to inhibit TAP is widely distributed among members of the genus Varicellovirus.

artículo científico publicado en 2010

The nested open reading frame in the Epstein-Barr virus nuclear antigen-1 mRNA encodes a protein capable of inhibiting antigen presentation in cis.

artículo científico publicado en 2007

The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex

scientific journal article

Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP.

artículo científico publicado en 2008

Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing

scientific journal article

Viral evasion of T cell immunity: ancient mechanisms offering new applications ⬇️

artículo científico publicado el 9 de diciembre de 2010

Viral inhibition of the transporter associated with antigen processing (TAP): a striking example of functional convergent evolution

artículo científico publicado en 2015

Viral interference with antigen presentation: trapping TAP.

artículo científico publicado en 2012

Lista de obras de

A CD8+ T cell immune evasion protein specific to Epstein-Barr virus and its close relatives in Old World primates

A bridge crosses the active-site canyon of the Epstein-Barr virus nuclease with DNase and RNase activities

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

Adenovirus-specific CD4+ T cell clones recognizing endogenous antigen inhibit viral replication in vitro through cognate interaction

Alternative Ii-independent antigen-processing pathway in leukemic blasts involves TAP-dependent peptide loading of HLA class II complexes ⬇️

An alternative model for type I interferon induction downstream of human TLR2

Balancing STING in antimicrobial defense and autoinflammation

CD200 receptor controls sex-specific TLR7 responses to viral infection

Cellular immunity against human papillomavirus associated cervical cancer

Chemical Tools for Studying TLR Signaling Dynamics

Conditionally Controlling Human TLR2 Activity via Trans-Cyclooctene Caged Ligands

Cowpox virus protein CPXV012 eludes CTLs by blocking ATP binding to TAP.

EBV BILF1 evolved to downregulate cell surface display of a wide range of HLA class I molecules through their cytoplasmic tail

EBV MicroRNA BART16 Suppresses Type I IFN Signaling.

EBV lytic-phase protein BGLF5 contributes to TLR9 downregulation during productive infection.

EBV protein BNLF2a exploits host tail-anchored protein integration machinery to inhibit TAP.

Epstein-Barr virus evasion of CD8(+) and CD4(+) T cell immunity via concerted actions of multiple gene products.

Epstein-Barr virus gp42 is posttranslationally modified to produce soluble gp42 that mediates HLA class II immune evasion.

Epstein-Barr virus isolates retain their capacity to evade T cell immunity through BNLF2a despite extensive sequence variation

Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling

Evaluation of viral interference with MHC class I-restricted antigen processing and presentation using a flow cytometry-based approach

Exploiting human herpesvirus immune evasion for therapeutic gain: potential and pitfalls ⬇️

Herpesvirus interference with major histocompatibility complex class II-restricted T-cell activation

Hiding lipid presentation: viral interference with CD1d-restricted invariant natural killer T (iNKT) cell activation

Host shutoff during productive Epstein-Barr virus infection is mediated by BGLF5 and may contribute to immune evasion

Human B cells fail to secrete type I interferons upon cytoplasmic DNA exposure

Human cytomegalovirus-encoded US2 differentially affects surface expression of MHC class I locus products and targets membrane-bound, but not soluble HLA-G1 for degradation

Immune Evasion by Epstein-Barr Virus

Impaired transporter associated with antigen processing-dependent peptide transport during productive EBV infection

Inflammasomes and viruses: cellular defence versus viral offence

Inhibition of mouse TAP by immune evasion molecules encoded by non-murine herpesviruses

Interference with T cell receptor–HLA-DR interactions by Epstein–Barr virus gp42 results in reduced T helper cell recognition ⬇️

Manipulation of the immune response by Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus: consequences for tumor development

Silencing the shutoff protein of Epstein-Barr virus in productively infected B cells points to (innate) targets for immune evasion

Specific targeting of the EBV lytic phase protein BNLF2a to the transporter associated with antigen processing results in impairment of HLA class I-restricted antigen presentation

Stage-specific inhibition of MHC class I presentation by the Epstein-Barr virus BNLF2a protein during virus lytic cycle

Structural and functional analysis of the TAP-inhibiting UL49.5 proteins of varicelloviruses.

TAP-inhibiting proteins US6, ICP47 and UL49.5 differentially affect minor and major histocompatibility antigen-specific recognition by cytotoxic T lymphocytes

The "Bridge" in the Epstein-Barr virus alkaline exonuclease protein BGLF5 contributes to shutoff activity during productive infection

The DNase of gammaherpesviruses impairs recognition by virus-specific CD8+ T cells through an additional host shutoff function

The Epstein-Barr Virus Glycoprotein gp150 Forms an Immune-Evasive Glycan Shield at the Surface of Infected Cells

The Epstein-Barr virus G-protein-coupled receptor contributes to immune evasion by targeting MHC class I molecules for degradation

The capacity of UL49.5 proteins to inhibit TAP is widely distributed among members of the genus Varicellovirus.

The nested open reading frame in the Epstein-Barr virus nuclear antigen-1 mRNA encodes a protein capable of inhibiting antigen presentation in cis.

The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex

Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP.

Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing

Viral evasion of T cell immunity: ancient mechanisms offering new applications ⬇️

Viral inhibition of the transporter associated with antigen processing (TAP): a striking example of functional convergent evolution

Viral interference with antigen presentation: trapping TAP.