Lista de obras -

A malaria parasite subtilisin propeptide-like protein is a potent inhibitor of the egress protease SUB1.

artículo científico publicado en 2020

A multifunctional serine protease primes the malaria parasite for red blood cell invasion

artículo científico publicado en 2009

An inhibitory antibody blocks interactions between components of the malarial invasion machinery

artículo científico publicado en 2009

Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor.

artículo científico publicado en 2021

Ca

artículo científico publicado en 2021

Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity identifies differences in amino acid preferences between peptide-based substrates and covalent inhibitors

scientific article published on 24 June 2019

Correction: Juxtamembrane Shedding of Plasmodium falciparum AMA1 Is Sequence Independent and Essential, and Helps Evade Invasion-Inhibitory Antibodies

artículo científico publicado en 2012

Corrigendum: The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin

artículo científico publicado en 2014

Crystal structure of the malaria vaccine candidate apical membrane antigen 1.

artículo científico publicado en 2005

Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery

scientific article published on 10 May 2019

Distinct mechanisms govern proteolytic shedding of a key invasion protein in apicomplexan pathogens

artículo científico publicado en 2005

Essentiality of Plasmodium falciparum plasmepsin V

artículo científico publicado en 2018

Expression of recombinant Plasmodium falciparum subtilisin-like protease-1 in insect cells. Characterization, comparison with the parasite protease, and homology modeling

artículo científico publicado en 2002

Fine mapping of an epitope recognized by an invasion-inhibitory monoclonal antibody on the malaria vaccine candidate apical membrane antigen 1.

artículo científico publicado en 2006

Global identification of multiple substrates for Plasmodium falciparum SUB1, an essential malarial processing protease

artículo científico publicado en 2011

High-Level Expression of the Malaria Blood-Stage Vaccine Candidate Plasmodium falciparum Apical Membrane Antigen 1 and Induction of Antibodies That Inhibit Erythrocyte Invasion.

artículo científico publicado en 2002

High-level expression of the malaria blood-stage vaccine candidate Plasmodium falciparum apical membrane antigen 1 and induction of antibodies that inhibit erythrocyte invasion ⬇️

artículo científico publicado en 2002

Identification of a Plasmodium falciparum phospholipid transfer protein

artículo científico publicado en 2013

Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite

artículo científico publicado en 2006

Juxtamembrane shedding of Plasmodium falciparum AMA1 is sequence independent and essential, and helps evade invasion-inhibitory antibodies ⬇️

artículo científico publicado en 2011

Malaria parasite cGMP-dependent protein kinase regulates blood stage merozoite secretory organelle discharge and egress

artículo científico publicado en 2013

Malarial EBA-175 region VI crystallographic structure reveals a KIX-like binding interface

artículo científico publicado en 2008

Molecular determinants for subcellular trafficking of the malarial sheddase PfSUB2.

artículo científico publicado en 2013

Molecular determinants of binding to the Plasmodium subtilisin-like protease 1.

artículo científico publicado en 2013

Molecular identification of a malaria merozoite surface sheddase

artículo científico publicado en 2005

Molecules incorporating a benzothiazole core scaffold inhibit the N-myristoyltransferase of Plasmodium falciparum.

artículo científico publicado en 2007

Peptidic boronic acids are potent cell-permeable inhibitors of the malaria parasite egress serine protease SUB1.

artículo científico

Peptidomimetic plasmepsin inhibitors with potent anti-malarial activity and selectivity against cathepsin D

artículo científico publicado en 2018

Plasmodium falciparum SERA5 plays a non-enzymatic role in the malarial asexual blood-stage lifecycle

artículo científico publicado en 2015

Plasmodium subtilisin-like protease 1 (SUB1): insights into the active-site structure, specificity and function of a pan-malaria drug target.

artículo científico publicado en 2012

Processing of Plasmodium falciparum Merozoite Surface Protein MSP1 Activates a Spectrin-Binding Function Enabling Parasite Egress from RBCs

artículo científico publicado en 2015

Proteolytic activation of the essential parasitophorous vacuole cysteine protease SERA6 accompanies malaria parasite egress from its host erythrocyte

artículo científico publicado en 2012

Simultaneous multiple allelic replacement in the malaria parasite enables dissection of PKG function

artículo científico publicado en 2020

Subcellular discharge of a serine protease mediates release of invasive malaria parasites from host erythrocytes

artículo científico publicado en 2007

Subtilisin-like proteases of the malaria parasite.

artículo científico publicado en 2004

Targeted Deletion of a Plasmodium Site-2 Protease Impairs Life Cycle Progression in the Mammalian Host

artículo científico publicado en 2017

The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin

artículo científico publicado en 2014

Unique insertions within Plasmodium falciparum subtilisin-like protease-1 are crucial for enzyme maturation and activity

artículo científico publicado en 2005

Lista de obras de

A malaria parasite subtilisin propeptide-like protein is a potent inhibitor of the egress protease SUB1.

A multifunctional serine protease primes the malaria parasite for red blood cell invasion

An inhibitory antibody blocks interactions between components of the malarial invasion machinery

Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor.

Ca

Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity identifies differences in amino acid preferences between peptide-based substrates and covalent inhibitors

Correction: Juxtamembrane Shedding of Plasmodium falciparum AMA1 Is Sequence Independent and Essential, and Helps Evade Invasion-Inhibitory Antibodies

Corrigendum: The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin

Crystal structure of the malaria vaccine candidate apical membrane antigen 1.

Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery

Distinct mechanisms govern proteolytic shedding of a key invasion protein in apicomplexan pathogens

Essentiality of Plasmodium falciparum plasmepsin V

Expression of recombinant Plasmodium falciparum subtilisin-like protease-1 in insect cells. Characterization, comparison with the parasite protease, and homology modeling

Fine mapping of an epitope recognized by an invasion-inhibitory monoclonal antibody on the malaria vaccine candidate apical membrane antigen 1.

Global identification of multiple substrates for Plasmodium falciparum SUB1, an essential malarial processing protease

High-Level Expression of the Malaria Blood-Stage Vaccine Candidate Plasmodium falciparum Apical Membrane Antigen 1 and Induction of Antibodies That Inhibit Erythrocyte Invasion.

High-level expression of the malaria blood-stage vaccine candidate Plasmodium falciparum apical membrane antigen 1 and induction of antibodies that inhibit erythrocyte invasion ⬇️

Identification of a Plasmodium falciparum phospholipid transfer protein

Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite

Juxtamembrane shedding of Plasmodium falciparum AMA1 is sequence independent and essential, and helps evade invasion-inhibitory antibodies ⬇️

Malaria parasite cGMP-dependent protein kinase regulates blood stage merozoite secretory organelle discharge and egress

Malarial EBA-175 region VI crystallographic structure reveals a KIX-like binding interface

Molecular determinants for subcellular trafficking of the malarial sheddase PfSUB2.

Molecular determinants of binding to the Plasmodium subtilisin-like protease 1.

Molecular identification of a malaria merozoite surface sheddase

Molecules incorporating a benzothiazole core scaffold inhibit the N-myristoyltransferase of Plasmodium falciparum.

Peptidic boronic acids are potent cell-permeable inhibitors of the malaria parasite egress serine protease SUB1.

Peptidomimetic plasmepsin inhibitors with potent anti-malarial activity and selectivity against cathepsin D

Plasmodium falciparum SERA5 plays a non-enzymatic role in the malarial asexual blood-stage lifecycle

Plasmodium subtilisin-like protease 1 (SUB1): insights into the active-site structure, specificity and function of a pan-malaria drug target.

Processing of Plasmodium falciparum Merozoite Surface Protein MSP1 Activates a Spectrin-Binding Function Enabling Parasite Egress from RBCs

Proteolytic activation of the essential parasitophorous vacuole cysteine protease SERA6 accompanies malaria parasite egress from its host erythrocyte

Simultaneous multiple allelic replacement in the malaria parasite enables dissection of PKG function

Subcellular discharge of a serine protease mediates release of invasive malaria parasites from host erythrocytes

Subtilisin-like proteases of the malaria parasite.

Targeted Deletion of a Plasmodium Site-2 Protease Impairs Life Cycle Progression in the Mammalian Host

The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin

Unique insertions within Plasmodium falciparum subtilisin-like protease-1 are crucial for enzyme maturation and activity