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5-Methyl--(8-(5,6,7,8-tetrahydroacridin-9-ylamino)octyl)-5-indolo[2,3-]quinolin-11-amine: a highly potent human cholinesterase inhibitor

artículo científico publicado en 2017

A practical two-step synthesis of imidazo[1,2-a]pyridines from N-(prop-2-yn-1-yl)pyridin-2-amines

artículo científico publicado en 2011

Alzheimer's Disease, the "One-Molecule, One-Target" Paradigm, and the Multitarget Directed Ligand Approach.

artículo científico publicado en 2018

Comparative Analysis of the Neurochemical Profile and MAO Inhibition Properties of N-(Furan-2-ylmethyl)-N-methylprop-2-yn-1-amine.

artículo científico publicado en 2016

Contilisant, a Tetratarget Small Molecule for Alzheimer's Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition, and H3R Antagonism with S1R Agonism Profile

artículo científico publicado en 2018

Controlled heterocyclization/cross-coupling domino reaction of β,γ-allendiols and α-allenic esters: method and mechanistic insight for the preparation of functionalized buta-1,3-dienyl dihydropyrans.

artículo científico publicado en 2013

Facts, Results, and Perspectives of the Current Alzheimer's Disease Research

scientific article published on 01 February 2019

Heterocyclization of allenes catalyzed by late transition metals: mechanisms and regioselectivity

artículo científico publicado en 2011

Metal-catalyzed cyclization of beta- and gamma-allenols derived from D-glyceraldehyde--synthesis of enantiopure dihydropyrans and tetrahydrooxepines: an experimental and theoretical study.

artículo científico publicado en 2009

Neuroinflammation Signaling Modulated by ASS234, a Multitarget Small Molecule for Alzheimer’s Disease Therapy

artículo científico publicado en 2018

New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition

artículo científico publicado en 2019

New Quinolylnitrones for Stroke Therapy: Antioxidant and Neuroprotective ( Z)- N- tert-Butyl-1-(2-chloro-6-methoxyquinolin-3-yl)methanimine Oxide as a New Lead-Compound for Ischemic Stroke Treatment

artículo científico publicado en 2019

Novel Quinolylnitrones Combining Neuroprotective and Antioxidant Properties

scientific article published on 09 April 2019

Quinolinyl Nitrone RP19 Induces Neuroprotection after Transient Brain Ischemia.

artículo científico publicado en 2017

Recent Advances on Nitrones Design for Stroke Treatment

scientific article published on 18 September 2020

Regioselectivity control in the metal-catalyzed O-C functionalization of gamma-allenols, part 1: Experimental study

artículo científico publicado en 2009

Regioselectivity control in the metal-catalyzed functionalization of gamma-allenols, part 2: Theoretical study.

artículo científico publicado en 2009

Synthesis and anti-HIV1 biological activity of novel 5''-ATSAO compounds

artículo científico publicado en 2008

Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer's disease therapy

artículo científico publicado en 2019

Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives

artículo científico publicado en 2020

Synthesis, anti-HIV-1 activity, and modeling studies of N-3 Boc TSAO compound

artículo científico publicado en 2008

Tacrines as Therapeutic Agents for Alzheimer's Disease. V. Recent Developments

artículo científico publicado en 2020

The reaction of 2-amino-4 $$H$$ H -pyrans with $$N$$ N -bromosuccinimide

artículo científico publicado en 2014