Lista de obras -

A pro-inflammatory role for the Frizzled-8 receptor in chronic bronchitis

artículo científico publicado en 2016

A sequence variant on 17q21 is associated with age at onset and severity of asthma

artículo científico publicado en 2010

ADAM33 gene polymorphisms and mortality. A prospective cohort study

artículo científico publicado en 2013

Acute and chronic inflammatory responses induced by smoking in individuals susceptible and non-susceptible to development of COPD: from specific disease phenotyping towards novel therapy. Protocol of a cross-sectional study

artículo científico publicado en 2013

Acute effects of cigarette smoking on inflammation in healthy intermittent smokers

artículo científico publicado en 2005

Advanced glycation endproducts and their receptor in different body compartments in COPD

artículo científico publicado en 2016

Ambient air pollution, lung function, and airway responsiveness in asthmatic children

artículo científico publicado en 2016

Antigen-specific active immunotherapy for ovarian cancer

artículo científico publicado en 2014

Antigen-specific active immunotherapy for ovarian cancer

artículo científico publicado en 2010

Antigen-specific active immunotherapy for ovarian cancer

artículo científico publicado en 2008

Associations between smoking, components of metabolic syndrome and lipoprotein particle size

artículo científico publicado en 2013

BMI and lifetime changes in BMI and cancer mortality risk

artículo científico publicado en 2015

CT-quantified emphysema in male heavy smokers: association with lung function decline

artículo científico publicado en 2011

Combined effects of smoking and alcohol on metabolic syndrome: the LifeLines cohort study

artículo científico publicado en 2014

Common genes underlying asthma and COPD? Genome-wide analysis on the Dutch hypothesis

artículo científico publicado en 2014

Common variants in the type 2 diabetes KCNQ1 gene are associated with impairments in insulin secretion during hyperglycaemic glucose clamp

artículo científico publicado en 2012

Correction: Susceptibility to chronic mucus hypersecretion, a genome wide association study

artículo científico publicado en 2015

Cytokine responses to stimulation of whole blood from patients with Buruli ulcer disease in Ghana

artículo científico publicado en 2005

Dissecting the genetics of chronic mucus hypersecretion in smokers with and without COPD.

artículo científico publicado en 2014

Doublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood-onset asthma and is expressed in testis and macrophages

artículo científico publicado en 2016

Eosinophil Count Is a Common Factor for Complex Metabolic and Pulmonary Traits and Diseases: The LifeLines Cohort Study

artículo científico publicado en 2016

Erratum: Corrigendum: Genetic Analysis in A Dutch Study Sample Identifies More Ulcerative Colitis Susceptibility Loci and Shows Their Additive Role in Disease Risk

scholarly article published in The American Journal of Gastroenterology

Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.

artículo científico publicado en 2017

Gender differences in respiratory symptoms in 19-year-old adults born preterm

artículo científico publicado en 2005

Genetic analysis in a Dutch study sample identifies more ulcerative colitis susceptibility loci and shows their additive role in disease risk

artículo científico publicado en 2009

Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP.

artículo científico publicado en 2008

Genetic evidence of assortative mating in humans

scholarly article

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

artículo científico publicado en 2017

Genome-Wide Association Study Identification of Novel Loci Associated with Airway Responsiveness in Chronic Obstructive Pulmonary Disease

artículo científico publicado en 2015

Genome-wide association analysis identifies six new loci associated with forced vital capacity

artículo científico publicado en 2014

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

artículo científico publicado en 2011

Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction

artículo científico publicado en 2012

Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction

scientific journal article

Genome-wide interaction study of gene-by-occupational exposure and effects on FEV1 levels

artículo científico publicado en 2015

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function

artículo científico publicado en 2012

Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD.

artículo científico publicado en 2012

Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study

artículo científico publicado en 2014

Identification of PCDH1 as a novel susceptibility gene for bronchial hyperresponsiveness

artículo científico publicado en 2009

Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants

artículo científico publicado en 2013

Increased activation of blood neutrophils after cigarette smoking in young individuals susceptible to COPD

artículo científico publicado en 2014

Integrative pathway genomics of lung function and airflow obstruction

artículo científico publicado en 2015

Lifetime Smoking History and Cause-Specific Mortality in a Cohort Study with 43 Years of Follow-Up

artículo científico publicado en 2016

Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population

artículo científico publicado en 2019

Longitudinal profile of bronchoalveolar lavage cell characteristics in patients with a good outcome after lung transplantation

artículo científico publicado en 2002

Microarray amplification bias: loss of 30% differentially expressed genes due to long probe - poly(A)-tail distances

artículo científico publicado en 2007

Multidrug resistance-associated protein 1 and lung function decline with or without long-term corticosteroids treatment in COPD ⬇️

artículo científico publicado el 12 de septiembre de 2012

Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD.

artículo científico publicado en 2010

Multiethnic Meta-analysis Identifies New Loci for Pulmonary Function

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

scientific article published in Nature Communications

NFE2L2 polymorphisms, mortality, and metabolism in the general population

artículo científico publicado en 2014

Nicotinic acetylcholine receptor variants are related to smoking habits, but not directly to COPD.

artículo científico publicado en 2012

No convincing association between genetic markers and respiratory symptoms: results of a GWA study

artículo científico publicado en 2017

Novel Genes for Airway Wall Thickness Identified with Combined Genome-Wide Association and Expression Analyses

article

Novel Genetic Susceptibility Loci for FEV1 in the Context of Occupational Exposure in Never-Smokers

artículo científico publicado en 2016

Novel childhood asthma genes interact with in utero and early-life tobacco smoke exposure

artículo científico publicado en 2013

Objective allergy markers and risk of cancer mortality and hospitalization in a large population-based cohort

artículo científico publicado en 2014

Occupational exposure to pesticides is associated with differential DNA methylation.

artículo científico publicado en 2018

Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report

artículo científico publicado en 2011

Pharmacokinetics of gemcitabine in non-small-cell lung cancer patients: impact of the 79A>C cytidine deaminase polymorphism

artículo científico publicado en 2010

Phase II study of docetaxel and carboplatin as second-line treatment in NSCLC.

artículo científico publicado en 2004

Prediction of Long-Term Benefits of Inhaled Steroids by Phenotypic Markers in Moderate-to-Severe COPD: A Randomized Controlled Trial

artículo científico publicado en 2015

Prevalence of asthma-like symptoms with ageing

artículo científico publicado en 2017

Rationale for the Dutch hypothesis. Allergy and airway hyperresponsiveness as genetic factors and their interaction with environment in the development of asthma and COPD.

artículo científico publicado en 2004

Risk factors for chronic mucus hypersecretion in individuals with and without COPD: influence of smoking and job exposure on CMH

scholarly article by Akkelies E Dijkstra et al published 18 March 2014 in Occupational and Environmental Medicine

SIRT1 polymorphism, long-term survival and glucose tolerance in the general population

artículo científico publicado en 2013

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

artículo científico publicado en 2009

Sulfatase modifying factor 1 (SUMF1) is associated with Chronic Obstructive Pulmonary Disease

artículo científico publicado en 2017

Susceptibility to chronic mucus hypersecretion, a genome wide association study

artículo científico publicado en 2014

TGF-β1 polymorphisms and asthma severity, airway inflammation, and remodeling

scientific article published on 27 October 2012

Toll-Like Receptor (TLR2 and TLR4) Polymorphisms and Chronic Obstructive Pulmonary Disease ⬇️

artículo científico publicado el 28 de agosto de 2012

Variants in the 15q24/25 locus associate with lung function decline in active smokers

artículo científico publicado en 2013

Very early discharge versus early discharge versus non-early discharge in children with cancer and febrile neutropenia

artículo científico publicado en 2016

Lista de obras de

A pro-inflammatory role for the Frizzled-8 receptor in chronic bronchitis

A sequence variant on 17q21 is associated with age at onset and severity of asthma

ADAM33 gene polymorphisms and mortality. A prospective cohort study

Acute and chronic inflammatory responses induced by smoking in individuals susceptible and non-susceptible to development of COPD: from specific disease phenotyping towards novel therapy. Protocol of a cross-sectional study

Acute effects of cigarette smoking on inflammation in healthy intermittent smokers

Advanced glycation endproducts and their receptor in different body compartments in COPD

Ambient air pollution, lung function, and airway responsiveness in asthmatic children

Antigen-specific active immunotherapy for ovarian cancer

Antigen-specific active immunotherapy for ovarian cancer

Antigen-specific active immunotherapy for ovarian cancer

Associations between smoking, components of metabolic syndrome and lipoprotein particle size

BMI and lifetime changes in BMI and cancer mortality risk

CT-quantified emphysema in male heavy smokers: association with lung function decline

Combined effects of smoking and alcohol on metabolic syndrome: the LifeLines cohort study

Common genes underlying asthma and COPD? Genome-wide analysis on the Dutch hypothesis

Common variants in the type 2 diabetes KCNQ1 gene are associated with impairments in insulin secretion during hyperglycaemic glucose clamp

Correction: Susceptibility to chronic mucus hypersecretion, a genome wide association study

Cytokine responses to stimulation of whole blood from patients with Buruli ulcer disease in Ghana

Dissecting the genetics of chronic mucus hypersecretion in smokers with and without COPD.

Doublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood-onset asthma and is expressed in testis and macrophages

Eosinophil Count Is a Common Factor for Complex Metabolic and Pulmonary Traits and Diseases: The LifeLines Cohort Study

Erratum: Corrigendum: Genetic Analysis in A Dutch Study Sample Identifies More Ulcerative Colitis Susceptibility Loci and Shows Their Additive Role in Disease Risk

Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.

Gender differences in respiratory symptoms in 19-year-old adults born preterm

Genetic analysis in a Dutch study sample identifies more ulcerative colitis susceptibility loci and shows their additive role in disease risk

Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP.

Genetic evidence of assortative mating in humans

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

Genome-Wide Association Study Identification of Novel Loci Associated with Airway Responsiveness in Chronic Obstructive Pulmonary Disease

Genome-wide association analysis identifies six new loci associated with forced vital capacity

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction

Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction

Genome-wide interaction study of gene-by-occupational exposure and effects on FEV1 levels

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function

Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD.

Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study

Identification of PCDH1 as a novel susceptibility gene for bronchial hyperresponsiveness

Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants

Increased activation of blood neutrophils after cigarette smoking in young individuals susceptible to COPD

Integrative pathway genomics of lung function and airflow obstruction

Lifetime Smoking History and Cause-Specific Mortality in a Cohort Study with 43 Years of Follow-Up

Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population

Longitudinal profile of bronchoalveolar lavage cell characteristics in patients with a good outcome after lung transplantation

Microarray amplification bias: loss of 30% differentially expressed genes due to long probe - poly(A)-tail distances

Multidrug resistance-associated protein 1 and lung function decline with or without long-term corticosteroids treatment in COPD ⬇️

Multidrug resistance-associated protein-1 (MRP1) genetic variants, MRP1 protein levels and severity of COPD.

Multiethnic Meta-analysis Identifies New Loci for Pulmonary Function

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

NFE2L2 polymorphisms, mortality, and metabolism in the general population

Nicotinic acetylcholine receptor variants are related to smoking habits, but not directly to COPD.

No convincing association between genetic markers and respiratory symptoms: results of a GWA study

Novel Genes for Airway Wall Thickness Identified with Combined Genome-Wide Association and Expression Analyses

Novel Genetic Susceptibility Loci for FEV1 in the Context of Occupational Exposure in Never-Smokers

Novel childhood asthma genes interact with in utero and early-life tobacco smoke exposure

Objective allergy markers and risk of cancer mortality and hospitalization in a large population-based cohort

Occupational exposure to pesticides is associated with differential DNA methylation.

Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report

Pharmacokinetics of gemcitabine in non-small-cell lung cancer patients: impact of the 79A>C cytidine deaminase polymorphism

Phase II study of docetaxel and carboplatin as second-line treatment in NSCLC.

Prediction of Long-Term Benefits of Inhaled Steroids by Phenotypic Markers in Moderate-to-Severe COPD: A Randomized Controlled Trial

Prevalence of asthma-like symptoms with ageing

Rationale for the Dutch hypothesis. Allergy and airway hyperresponsiveness as genetic factors and their interaction with environment in the development of asthma and COPD.

Risk factors for chronic mucus hypersecretion in individuals with and without COPD: influence of smoking and job exposure on CMH

SIRT1 polymorphism, long-term survival and glucose tolerance in the general population

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

Sulfatase modifying factor 1 (SUMF1) is associated with Chronic Obstructive Pulmonary Disease

Susceptibility to chronic mucus hypersecretion, a genome wide association study

TGF-β1 polymorphisms and asthma severity, airway inflammation, and remodeling

Toll-Like Receptor (TLR2 and TLR4) Polymorphisms and Chronic Obstructive Pulmonary Disease ⬇️

Variants in the 15q24/25 locus associate with lung function decline in active smokers

Very early discharge versus early discharge versus non-early discharge in children with cancer and febrile neutropenia