Lista de obras -

Altered distribution, aggregation, and protease resistance of cellular prion protein following intracranial inoculation

scientific article published on 10 July 2019

Amplified Detection of Prions and Other Amyloids by RT-QuIC in Diagnostics and the Evaluation of Therapeutics and Disinfectants

artículo científico publicado en 2017

An advanced BLT-humanized mouse model for extended HIV-1 cure studies.

artículo científico publicado en 2017

Antisense oligonucleotides extend survival of prion-infected mice

artículo científico publicado en 2019

BLT-humanized C57BL/6 Rag2-/-γc-/-CD47-/- mice are resistant to GVHD and develop B- and T-cell immunity to HIV infection

artículo científico publicado en 2013

Capillaries in the olfactory bulb but not the cortex are highly susceptible to virus-induced vascular leak and promote viral neuroinvasion

artículo científico

Cellular prion protein is present in mitochondria of healthy mice

artículo científico publicado en 2017

Characteristics of 263K scrapie agent in multiple hamster species

artículo científico publicado en 2009

Chronic wasting disease agents in nonhuman primates

artículo científico publicado en 2014

Concurrent administration of IFNα14 and cART in TKO-BLT mice enhances suppression of HIV-1 viremia but does not eliminate the latent reservoir

scientific article published on 02 December 2019

Crucial role for prion protein membrane anchoring in the neuroinvasion and neural spread of prion infection

artículo científico publicado en 2010

Detection of chronic wasting disease in mule and white-tailed deer by RT-QuIC analysis of outer ear

artículo científico publicado en 2021

Detection of prion infectivity in fat tissues of scrapie-infected mice

artículo científico publicado en 2008

Distinct patterns of spread of prion infection in brains of mice expressing anchorless or anchored forms of prion protein

artículo científico publicado en 2014

Early Cytokine Elevation, PrPres Deposition, and Gliosis in Mouse Scrapie: No Effect on Disease by Deletion of Cytokine Genes IL-12p40 and IL-12p35 ⬇️

artículo científico publicado el 11 de julio de 2012

Early Generation of New PrPSc on Blood Vessels after Brain Microinjection of Scrapie in Mice

artículo científico publicado en 2015

Early preclinical detection of prions in the skin of prion-infected animals

artículo científico publicado en 2019

Essential roles for CD8+ T cells and gamma interferon in protection of mice against retrovirus-induced immunosuppression

artículo científico publicado en 2002

Familial human prion diseases associated with prion protein mutations Y226X and G131V are transmissible to transgenic mice expressing human prion protein.

artículo científico publicado en 2018

Fatal transmissible amyloid encephalopathy: a new type of prion disease associated with lack of prion protein membrane anchoring

artículo científico publicado en 2010

Genetic background modulates outcome of therapeutic amyloid peptides in treatment of neuroinflammation

artículo científico publicado en 2016

Human cerebral organoids as a therapeutic drug screening model for Creutzfeldt-Jakob disease

artículo científico publicado en 2021

In Vivo Comparison of Chronic Wasting Disease Infectivity from Deer with Variation at Prion Protein Residue 96 ⬇️

artículo científico publicado el 22 de junio de 2011

Inactivation of Prions and Amyloid Seeds with Hypochlorous Acid

artículo científico publicado en 2016

Inactivation of chronic wasting disease prions using sodium hypochlorite

artículo científico publicado en 2019

Increased infectivity of anchorless mouse scrapie prions in transgenic mice overexpressing human prion protein

artículo científico publicado en 2015

Interferon Alpha Subtype-Specific Suppression of HIV-1 Infection In Vivo

artículo científico publicado en 2016

Isolation of novel synthetic prion strains by amplification in transgenic mice coexpressing wild-type and anchorless prion proteins

artículo científico publicado en 2012

Knockout of fractalkine receptor Cx3cr1 does not alter disease or microglial activation in prion-infected mice

artículo científico publicado en 2016

Lack of Transmission of Chronic Wasting Disease to Cynomolgus Macaques

artículo científico publicado en 2018

Lower specific infectivity of protease-resistant prion protein generated in cell-free reactions

artículo científico publicado en 2011

Mammalian prions generated from bacterially expressed prion protein in the absence of any mammalian cofactors

artículo científico publicado en 2010

Microglia Are Critical in Host Defense Against Prion Disease.

artículo científico publicado en 2018

Microglia are not required for prion-induced retinal photoreceptor degeneration

artículo científico publicado en 2019

Phosphorylated human tau associates with mouse prion protein amyloid in scrapie-infected mice but does not increase progression of clinical disease

artículo científico publicado en 2016

PrP P102L and nearby lysine mutations promote spontaneous in vitro formation of transmissible prions

artículo científico publicado en 2017

Prion Strain Differences in Accumulation of PrPSc on Neurons and Glia Are Associated with Similar Expression Profiles of Neuroinflammatory Genes: Comparison of Three Prion Strains

artículo científico publicado en 2016

Prion infection of mouse brain reveals multiple new upregulated genes involved in neuroinflammation or signal transduction

artículo científico publicado en 2014

Prion infectivity in fat of deer with chronic wasting disease

artículo científico publicado en 2009

Prion protein N1 cleavage peptides stimulate microglial interaction with surrounding cells

artículo científico publicado en 2020

Prion protein and susceptibility to kainate-induced seizures: genetic pitfalls in the use of PrP knockout mice

artículo científico publicado en 2013

Prion protein on astrocytes or in extracellular fluid impedes neurodegeneration induced by truncated prion protein

artículo científico publicado en 2009

Prion seeding activities of mouse scrapie strains with divergent PrPSc protease sensitivities and amyloid plaque content using RT-QuIC and eQuIC

artículo científico publicado en 2012

Prion-associated cerebral amyloid angiopathy is not exacerbated by human phosphorylated tau aggregates in scrapie-infected mice expressing anchorless prion protein

scientific article published on 20 August 2020

Prion-induced photoreceptor degeneration begins with misfolded prion protein accumulation in cones at two distinct sites: cilia and ribbon synapses

artículo científico publicado en 2021

Processing of high-titer prions for mass spectrometry inactivates prion infectivity

scientific article published on 20 August 2018

Production of bone marrow, liver, thymus (BLT) humanized mice on the C57BL/6 Rag2(-/-)γc(-/-)CD47(-/-) background

artículo científico publicado en 2014

Publisher Correction: Early preclinical detection of prions in the skin of prion-infected animals

artículo científico publicado en 2019

RNA-seq and network analysis reveal unique glial gene expression signatures during prion infection

artículo científico publicado en 2020

Rapid End-Point Quantitation of Prion Seeding Activity with Sensitivity Comparable to Bioassays ⬇️

artículo científico publicado el 2 de diciembre de 2010

Reduction of Chronic Wasting Disease Prion Seeding Activity following Digestion by Mountain Lions

artículo científico publicado en 2021

Reply to Karapetyan: Viral synthesis and assembly is unlikely to occur under cell-free PMCA conditions.

artículo científico publicado en 2012

Resistance to chronic wasting disease in transgenic mice expressing a naturally occurring allelic variant of deer prion protein

artículo científico publicado en 2007

Role of the central lysine cluster and scrapie templating in the transmissibility of synthetic prion protein aggregates.

artículo científico publicado en 2017

Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids.

artículo científico publicado en 2019

Statins are ineffective at reducing neuroinflammation or prolonging survival in scrapie-infected mice

artículo científico publicado en 2017

Strain Specific Resistance to Murine Scrapie Associated with a Naturally Occurring Human Prion Protein Polymorphism at Residue 171 ⬇️

artículo científico publicado el 29 de septiembre de 2011

Susceptibilities of nonhuman primates to chronic wasting disease

artículo científico publicado en 2009

Temporal effects of gamma interferon deficiency on the course of Friend retrovirus infection in mice

artículo científico publicado en 2002

Time Course of Prion Seeding Activity in Cerebrospinal Fluid of Scrapie-Infected Hamsters after Intratongue and Intracerebral Inoculations ⬇️

artículo científico publicado el 11 de enero de 2012

Toll-like receptor 2 confers partial neuroprotection during prion disease

scientific article published in PLoS ONE

Transmission of CJD from nasal brushings but not spinal fluid or RT-QuIC product

artículo científico publicado en 2020

Transmission studies of chronic wasting disease to transgenic mice overexpressing human prion protein using the RT-QuIC assay

article

Ultrastructure and pathology of prion protein amyloid accumulation and cellular damage in extraneural tissues of scrapie-infected transgenic mice expressing anchorless prion protein

artículo científico publicado en 2017

Unusual cerebral vascular prion protein amyloid distribution in scrapie-infected transgenic mice expressing anchorless prion protein

artículo científico publicado en 2013

Lista de obras de

Altered distribution, aggregation, and protease resistance of cellular prion protein following intracranial inoculation

Amplified Detection of Prions and Other Amyloids by RT-QuIC in Diagnostics and the Evaluation of Therapeutics and Disinfectants

An advanced BLT-humanized mouse model for extended HIV-1 cure studies.

Antisense oligonucleotides extend survival of prion-infected mice

BLT-humanized C57BL/6 Rag2-/-γc-/-CD47-/- mice are resistant to GVHD and develop B- and T-cell immunity to HIV infection

Capillaries in the olfactory bulb but not the cortex are highly susceptible to virus-induced vascular leak and promote viral neuroinvasion

Cellular prion protein is present in mitochondria of healthy mice

Characteristics of 263K scrapie agent in multiple hamster species

Chronic wasting disease agents in nonhuman primates

Concurrent administration of IFNα14 and cART in TKO-BLT mice enhances suppression of HIV-1 viremia but does not eliminate the latent reservoir

Crucial role for prion protein membrane anchoring in the neuroinvasion and neural spread of prion infection

Detection of chronic wasting disease in mule and white-tailed deer by RT-QuIC analysis of outer ear

Detection of prion infectivity in fat tissues of scrapie-infected mice

Distinct patterns of spread of prion infection in brains of mice expressing anchorless or anchored forms of prion protein

Early Cytokine Elevation, PrPres Deposition, and Gliosis in Mouse Scrapie: No Effect on Disease by Deletion of Cytokine Genes IL-12p40 and IL-12p35 ⬇️

Early Generation of New PrPSc on Blood Vessels after Brain Microinjection of Scrapie in Mice

Early preclinical detection of prions in the skin of prion-infected animals

Essential roles for CD8+ T cells and gamma interferon in protection of mice against retrovirus-induced immunosuppression

Familial human prion diseases associated with prion protein mutations Y226X and G131V are transmissible to transgenic mice expressing human prion protein.

Fatal transmissible amyloid encephalopathy: a new type of prion disease associated with lack of prion protein membrane anchoring

Genetic background modulates outcome of therapeutic amyloid peptides in treatment of neuroinflammation

Human cerebral organoids as a therapeutic drug screening model for Creutzfeldt-Jakob disease

In Vivo Comparison of Chronic Wasting Disease Infectivity from Deer with Variation at Prion Protein Residue 96 ⬇️

Inactivation of Prions and Amyloid Seeds with Hypochlorous Acid

Inactivation of chronic wasting disease prions using sodium hypochlorite

Increased infectivity of anchorless mouse scrapie prions in transgenic mice overexpressing human prion protein

Interferon Alpha Subtype-Specific Suppression of HIV-1 Infection In Vivo

Isolation of novel synthetic prion strains by amplification in transgenic mice coexpressing wild-type and anchorless prion proteins

Knockout of fractalkine receptor Cx3cr1 does not alter disease or microglial activation in prion-infected mice

Lack of Transmission of Chronic Wasting Disease to Cynomolgus Macaques

Lower specific infectivity of protease-resistant prion protein generated in cell-free reactions

Mammalian prions generated from bacterially expressed prion protein in the absence of any mammalian cofactors

Microglia Are Critical in Host Defense Against Prion Disease.

Microglia are not required for prion-induced retinal photoreceptor degeneration

Phosphorylated human tau associates with mouse prion protein amyloid in scrapie-infected mice but does not increase progression of clinical disease

PrP P102L and nearby lysine mutations promote spontaneous in vitro formation of transmissible prions

Prion Strain Differences in Accumulation of PrPSc on Neurons and Glia Are Associated with Similar Expression Profiles of Neuroinflammatory Genes: Comparison of Three Prion Strains

Prion infection of mouse brain reveals multiple new upregulated genes involved in neuroinflammation or signal transduction

Prion infectivity in fat of deer with chronic wasting disease

Prion protein N1 cleavage peptides stimulate microglial interaction with surrounding cells

Prion protein and susceptibility to kainate-induced seizures: genetic pitfalls in the use of PrP knockout mice

Prion protein on astrocytes or in extracellular fluid impedes neurodegeneration induced by truncated prion protein

Prion seeding activities of mouse scrapie strains with divergent PrPSc protease sensitivities and amyloid plaque content using RT-QuIC and eQuIC

Prion-associated cerebral amyloid angiopathy is not exacerbated by human phosphorylated tau aggregates in scrapie-infected mice expressing anchorless prion protein

Prion-induced photoreceptor degeneration begins with misfolded prion protein accumulation in cones at two distinct sites: cilia and ribbon synapses

Processing of high-titer prions for mass spectrometry inactivates prion infectivity

Production of bone marrow, liver, thymus (BLT) humanized mice on the C57BL/6 Rag2(-/-)γc(-/-)CD47(-/-) background

Publisher Correction: Early preclinical detection of prions in the skin of prion-infected animals

RNA-seq and network analysis reveal unique glial gene expression signatures during prion infection

Rapid End-Point Quantitation of Prion Seeding Activity with Sensitivity Comparable to Bioassays ⬇️

Reduction of Chronic Wasting Disease Prion Seeding Activity following Digestion by Mountain Lions

Reply to Karapetyan: Viral synthesis and assembly is unlikely to occur under cell-free PMCA conditions.

Resistance to chronic wasting disease in transgenic mice expressing a naturally occurring allelic variant of deer prion protein

Role of the central lysine cluster and scrapie templating in the transmissibility of synthetic prion protein aggregates.

Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids.

Statins are ineffective at reducing neuroinflammation or prolonging survival in scrapie-infected mice

Strain Specific Resistance to Murine Scrapie Associated with a Naturally Occurring Human Prion Protein Polymorphism at Residue 171 ⬇️

Susceptibilities of nonhuman primates to chronic wasting disease

Temporal effects of gamma interferon deficiency on the course of Friend retrovirus infection in mice

Time Course of Prion Seeding Activity in Cerebrospinal Fluid of Scrapie-Infected Hamsters after Intratongue and Intracerebral Inoculations ⬇️

Toll-like receptor 2 confers partial neuroprotection during prion disease

Transmission of CJD from nasal brushings but not spinal fluid or RT-QuIC product

Transmission studies of chronic wasting disease to transgenic mice overexpressing human prion protein using the RT-QuIC assay

Ultrastructure and pathology of prion protein amyloid accumulation and cellular damage in extraneural tissues of scrapie-infected transgenic mice expressing anchorless prion protein

Unusual cerebral vascular prion protein amyloid distribution in scrapie-infected transgenic mice expressing anchorless prion protein