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A high-performance waveguide-mode biosensor for detection of factor IX using PEG-based blocking agents to suppress non-specific binding and improve sensitivity

artículo científico publicado en 2013

A novel biointerface that suppresses cell morphological changes by scavenging excess reactive oxygen species

artículo científico publicado en 2015

A novel nitric oxide-based anticancer therapeutics by macrophage-targeted poly(l-arginine)-based nanoparticles

artículo científico publicado en 2015

A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo.

artículo científico publicado en 2009

An anti-oxidative cell culture dish inhibits intracellular reactive oxygen species accumulation and modulates pluripotency-associated gene expression in mesenchymal stem cells

scientific article published on 04 March 2020

An orally administered redox nanoparticle that accumulates in the colonic mucosa and reduces colitis in mice

artículo científico publicado en 2012

Anti-cancer vaccination by transdermal delivery of antigen peptide-loaded nanogels via iontophoresis

artículo científico publicado en 2015

Antioxidant Nanomedicine Protects against Ionizing Radiation-Induced Life-Shortening in C57BL/6J Mice

scientific article published on 11 March 2019

Antioxidant Nanomedicine with Cytoplasmic Distribution in Neuronal Cells Shows Superior Neurovascular Protection Properties

artículo científico publicado en 2020

Antioxidative Nanoparticles Significantly Enhance Therapeutic Efficacy of an Antibacterial Therapy against Listeria monocytogenes Infection.

artículo científico publicado en 2018

Antioxidative biointerface: biocompatible materials scavenging reactive oxygen species

artículo científico publicado en 2018

Application of surface enhanced Raman spectroscopy as a diagnostic system for hypersialylated metastatic cancers

artículo científico publicado en 2017

Binding enhancement of antigen-functionalized PEGylated gold nanoparticles onto antibody-immobilized surface by increasing the functionalized antigen using alpha-sulfanyl-omega-amino-PEG.

artículo científico publicado en 2008

Block ionomer complexes of PEG-block-poly(4-vinylbenzylphosphonate) and cationic surfactants as highly stable, pH responsive drug delivery system.

artículo científico publicado en 2012

Characterization of aldehyde-PEG tethered surfaces: influence of PEG chain length on the specific biorecognition

artículo científico publicado en 2004

Chemical nanotherapy: nitroxyl radical-containing nanoparticle protects neuroblastoma SH-SY5Y cells from Abeta-induced oxidative stress.

artículo científico publicado en 2011

Chronic treatment with a smart antioxidative nanoparticle for inhibition of amyloid plaque propagation in Tg2576 mouse model of Alzheimer's disease

artículo científico publicado en 2017

Co-immobilized poly(ethylene glycol)-block-polyamines promote sensitivity and restrict biofouling on gold sensor surface for detecting factor IX in human plasma

artículo científico

Coffee component hydroxyl hydroquinone (HHQ) as a putative ligand for PPAR gamma and implications in breast cancer

artículo científico publicado en 2013

Colloidal Au replacement assay for highly sensitive quantification of low molecular weight analytes by surface plasmon resonance

artículo científico publicado en 2007

Combination Treatment of Murine Colon Cancer with Doxorubicin and Redox Nanoparticles

artículo científico publicado en 2015

Completely dispersible PEGylated gold nanoparticles under physiological conditions: modification of gold nanoparticles with precisely controlled PEG-b-polyamine

scientific article published on 04 April 2008

Creation of a blood-compatible surface: a novel strategy for suppressing blood activation and coagulation using a nitroxide radical-containing polymer with reactive oxygen species scavenging activity

scientific article published on 02 December 2011

Creation of a mixed poly(ethylene glycol) tethered-chain surface for preventing the nonspecific adsorption of proteins and peptides

artículo científico publicado en 2007

Density control of poly(ethylene glycol) layer to regulate cellular attachment

artículo científico publicado en 2007

Design and Preparation of a Nanoprobe for Imaging Inflammation Sites

artículo científico publicado en 2012

Design and use of silica-containing redox nanoparticles, siRNPs, for high-performance peritoneal dialysis.

artículo científico publicado en 2014

Design of amino acid-based self-assembled nano-drugs for therapeutic applications

scientific article published on 17 June 2020

Design of core--shell-type nanoparticles carrying stable radicals in the core

artículo científico publicado en 2009

Design of poly(ethylene glycol)/streptavidin coimmobilized upconversion nanophosphors and their application to fluorescence biolabeling

artículo científico publicado en 2008

Development of a high-performance immunolatex based on "soft landing" antibody immobilization mechanism

scientific article published on 29 September 2011

Development of a long-acting, protein-loaded, redox-active, injectable gel formed by a polyion complex for local protein therapeutics

artículo científico publicado en 2016

Development of an oral nanotherapeutics using redox nanoparticles for treatment of colitis-associated colon cancer.

artículo científico publicado en 2015

Development of nitroxide radicals-containing polymer for scavenging reactive oxygen species from cigarette smoke

artículo científico publicado en 2014

Development of silica-containing redox nanoparticles for medical applications.

artículo científico publicado en 2015

Different mechanisms of action of poly(ethylene glycol) and arginine on thermal inactivation of lysozyme and ribonuclease A

artículo científico publicado en 2012

Direct observation of adsorption-induced inactivation of antibody fragments surrounded by mixed-PEG layer on a gold surface

artículo científico publicado en 2010

Efficient inhibition of interfacial nonspecific interaction to create practically utilizable high ferritin-response immunolatex

artículo científico publicado en 2009

Efficient short interference RNA delivery to tumor cells using a combination of octaarginine, GALA and tumor-specific, cleavable polyethylene glycol system

artículo científico publicado en 2009

Efficient siRNA delivery based on PEGylated and partially quaternized polyamine nanogels: enhanced gene silencing activity by the cooperative effect of tertiary and quaternary amino groups in the core

artículo científico publicado en 2010

Electric stimulus opens intercellular spaces in skin.

artículo científico publicado en 2013

Elevated atherogenic index following oral administration of quaternized polyamine nanogels

artículo científico publicado en 2013

Encapsulation of tissue plasminogen activator in pH-sensitive self-assembled antioxidant nanoparticles for ischemic stroke treatment - Synergistic effect of thrombolysis and antioxidant

scientific article published on 13 May 2019

Engineering of poly(ethylene glycol) chain-tethered surfaces to obtain high-performance bionanoparticles

artículo científico publicado en 2010

Enhanced cytoplasmic delivery of siRNA using a stabilized polyion complex based on PEGylated nanogels with a cross-linked polyamine structure.

artículo científico publicado en 2009

Enhanced growth inhibition of hepatic multicellular tumor spheroids by lactosylated poly(ethylene glycol)-siRNA conjugate formulated in PEGylated polyplexes

artículo científico publicado en 2007

Enhanced immunoresponse of antibody/mixed-PEG co-immobilized surface construction of high-performance immunomagnetic ELISA system

artículo científico publicado en 2007

Enhanced intracellular drug delivery of pH-sensitive doxorubicin/poly(ethylene glycol)-block-poly(4-vinylbenzylphosphonate) nanoparticles in multi-drug resistant human epidermoid KB carcinoma cells

scientific article published on 30 January 2013

Evaluation of the in vivo antioxidative activity of redox nanoparticles by using a developing chicken egg as an alternative animal model

scientific article published on 15 March 2014

Facile and Quantitative Synthesis of a Poly(ethylene glycol)-b-Poly(l-arginine) Block Copolymer and Its Use for the Preparation of Polyion Complex Micelles with Polyanions for Biomedical Applications

artículo científico publicado en 2015

Facile construction of sulfanyl-terminated poly(ethylene glycol)-brushed layer on a gold surface for protein immobilization by the combined use of sulfanyl-ended telechelic and semitelechelic poly(ethylene glycol)s

artículo científico publicado en 2008

Facile solid-phase synthesis of a highly stable poly(ethylene glycol)-oligonucleotide conjugate

scientific article published on 21 November 2012

Fibrinolytic tissue plasminogen activator installed redox-active nanoparticles (t-PA@iRNP) for cancer therapy

scientific article published on 14 August 2020

Fluorescence-based affinity labeling of nucleobase by hydrogen-bond forming metal complex.

artículo científico publicado en 2007

Gd@C82 metallofullerenes for neutron capture therapy-fullerene solubilization by poly(ethylene glycol)-block-poly(2-(N, N-diethylamino)ethyl methacrylate) and resultant efficacy in vitro

artículo científico publicado en 2011

Glycolytic enzymes PGK1 and PKM2 as novel transcriptional targets of PPARγ in breast cancer pathophysiology ⬇️

artículo científico publicado el 6 de noviembre de 2012

High PEGylation efficiency of pentaethylenehexamine-end poly(ethylene glycol) (mPEG-N6) for active-ester surface

artículo científico publicado en 2011

High-performance immunolatex possessing a mixed-PEG/antibody coimmobilized surface: highly sensitive ferritin immunodiagnostics

artículo científico publicado en 2009

High-performance surface acoustic wave immunosensing system on a PEG/aptamer hybridized surface.

artículo científico publicado en 2013

Improved complementary polymer pair system: switching for enzyme activity by PEGylated polymers

artículo científico publicado en 2012

Improving the heat resistance of ribonuclease A by the addition of poly(N,N-diethylaminoethyl methacrylate)-graft-poly(ethylene glycol) (PEAMA-g-PEG).

artículo científico publicado en 2010

In vitro and in vivo characteristics of core–shell type nanogel particles: Optimization of core cross-linking density and surface poly(ethylene glycol) density in PEGylated nanogels ⬇️

artículo científico publicado el 27 de mayo de 2011

Indomethacin-loaded redox nanoparticles improve oral bioavailability of indomethacin and suppress its small intestinal inflammation.

artículo científico publicado en 2014

Intra-tumor distribution of metallofullerene using micro-particle induced X-ray emission (PIXE).

artículo científico publicado en 2014

Intracellular inducible alkylation system that exhibits antisense effects with greater potency and selectivity than the natural oligonucleotide

scientific article published on 01 May 2006

Lactose-installed poly(ethylene glycol)-poly(d,l-lactide) block copolymer micelles exhibit fast-rate binding and high affinity toward a protein bed simulating a cell surface. A surface plasmon resonance study

artículo científico publicado en 2003

Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells.

artículo científico publicado en 2005

Large payloads of gold nanoparticles into the polyamine network core of stimuli-responsive PEGylated nanogels for selective and noninvasive cancer photothermal therapy.

artículo científico publicado en 2010

Ligand density effect on biorecognition by PEGylated gold nanoparticles: regulated interaction of RCA120 lectin with lactose installed to the distal end of tethered PEG strands on gold surface

artículo científico publicado en 2005

Long-term bioavailability of redox nanoparticles effectively reduces organ dysfunctions and death in whole-body irradiated mice

artículo científico publicado en 2017

Long-term survival and functional maintenance of hepatocytes by using a microfabricated cell array ⬇️

artículo científico publicado el 21 de abril de 2012

Molecular design of a high-performance polymeric carrier for delivery of a variety of boronic acid-containing drugs

artículo científico publicado en 2020

Near-infrared (1550 nm) in vivo bioimaging based on rare-earth doped ceramic nanophosphors modified with PEG-b-poly(4-vinylbenzylphosphonate)

artículo científico publicado en 2011

Neurovascular Unit Protection From Cerebral Ischemia-Reperfusion Injury by Radical-Containing Nanoparticles in Mice.

artículo científico publicado en 2017

Newly Designed Silica-Containing Redox Nanoparticles for Oral Delivery of Novel TOP2 Catalytic Inhibitor for Treating Colon Cancer.

artículo científico publicado en 2017

Newly synthesized radical-containing nanoparticles enhance neuroprotection after cerebral ischemia-reperfusion injury

artículo científico publicado en 2011

Nitric Oxide Nano-Delivery Systems for Cancer Therapeutics: Advances and Challenges

artículo científico publicado en 2020

Nitroxide Radicals and Nanoparticles: a Partnership for Nanomedicine Radical Delivery ⬇️

artículo científico publicado el 1 de febrero de 2012

Nitroxide radical-containing nanoparticles attenuate tumorigenic potential of triple negative breast cancer

artículo científico publicado en 2018

Nitroxyl radical-containing nanoparticles for novel nanomedicine against oxidative stress injury.

artículo científico publicado en 2011

Non-Fouling Character of Poly[2-(methacryloyloxy)ethyl Phosphorylcholine]-Modified Gold Surfaces Fabricated by the 'Grafting to' Method: Comparison of its Protein Resistance with Poly(ethylene glycol)-Modified Gold Surfaces

artículo científico publicado en 2009

Non-isotope enriched phenylboronic acid-decorated dual-functional nano-assembles for an actively targeting BNCT drug

artículo científico publicado en 2020

Novel Synthesized Radical-Containing Nanoparticles Limit Infarct Size Following Ischemia and Reperfusion in Canine Hearts

artículo científico publicado en 2017

Novel angiogenesis therapeutics by redox injectable hydrogel - Regulation of local nitric oxide generation for effective cardiovascular therapy

artículo científico publicado en 2018

Novel antioxidative nanotherapeutics in a rat periodontitis model: Reactive oxygen species scavenging by redox injectable gel suppresses alveolar bone resorption

artículo científico publicado en 2015

Novel biocompatible nanoreactor for silica/gold hybrid nanoparticles preparation ⬇️

artículo científico publicado el 27 de septiembre de 2012

Novel molecular recognition via fluorescent resonance energy transfer using a biotin-PEG/polyamine stabilized CdS quantum dot.

artículo científico publicado en 2004

Novel neuroprotection using antioxidant nanoparticles in a mouse model of head trauma

artículo científico publicado en 2020

Novel oligonucleotide carrier as scavenger for reactive oxygen species

article

Novel protein PEGylation chemistry via glutalaldehyde-functionalized PEG.

artículo científico publicado en 2013

Novel redox nanomedicine improves gene expression of polyion complex vector.

artículo científico publicado en 2011

On-off regulation of 19F magnetic resonance signals based on pH-sensitive PEGylated nanogels for potential tumor-specific smart 19F MRI probes

artículo científico publicado en 2007

Oral nanotherapeutics: Redox nanoparticles attenuate ultraviolet B radiation-induced skin inflammatory disorders in Kud:Hr- hairless mice

artículo científico publicado en 2017

Oral nanotherapeutics: effect of redox nanoparticle on microflora in mice with dextran sodium sulfate-induced colitis ⬇️

artículo científico publicado el 29 de mayo de 2013

PEGylated nanoparticles for biological and pharmaceutical applications

artículo científico publicado en 2003

Pharmacokinetics of core-polymerized, boron-conjugated micelles designed for boron neutron capture therapy for cancer.

artículo científico publicado en 2012

Physicochemical characterization of densely packed poly(ethylene glycol) layer for minimizing nonspecific protein adsorption

artículo científico publicado en 2007

Poly(ornithine)-based self-assembling drug for recovery of hyperammonemia and damage in acute liver injury

artículo científico publicado en 2019

Preparation of a novel PEG-clay hybrid as a DDS material: dispersion stability and sustained release profiles

artículo científico publicado en 2005

Preparation of functionally Pegylated gold nanoparticles with narrow distribution through autoreduction of auric cation by alpha-biotinyl-PEG-block-[poly(2- (N,N-dimethylamino)ethyl methacrylate)].

artículo científico publicado en 2004

Preparation of highly dispersible and tumor-accumulative, iron oxide nanoparticles Multi-point anchoring of PEG-b-poly(4-vinylbenzylphosphonate) improves performance significantly

artículo científico publicado en 2011

Prevention of UV-Induced Melanin Production by Accumulation of Redox Nanoparticles in the Epidermal Layer via Iontophoresis

artículo científico publicado en 2017

Protection of Coral Larvae from Thermally Induced Oxidative Stress by Redox Nanoparticles

artículo científico publicado en 2018

Radiosensitization of tumor cells through endoplasmic reticulum stress induced by PEGylated nanogel containing gold nanoparticles.

artículo científico publicado en 2014

Reactive oxygen species-scavenging nanomedicines for the treatment of oxidative stress injuries

artículo científico publicado en 2014

Recovery of Cognitive Dysfunction via Orally Administered Redox-Polymer Nanotherapeutics in SAMP8 Mice

artículo científico publicado en 2015

Redox Nanoparticle Therapeutics for Acetaminophen-Induced Hepatotoxicity in Mice

artículo científico publicado en 2016

Redox injectable gel protects osteoblastic function against oxidative stress and suppresses alveolar bone loss in a rat peri-implantitis model

scientific article published on 26 April 2020

Redox nanoparticle increases the chemotherapeutic efficiency of pioglitazone and suppresses its toxic side effects.

artículo científico publicado en 2016

Redox nanoparticle therapeutics to cancer — increase in therapeutic effect of doxorubicin, suppressing its adverse effect ⬇️

artículo científico publicado el 17 de agosto de 2013

Redox nanoparticle treatment protects against neurological deficit in focused ultrasound-induced intracerebral hemorrhage

artículo científico publicado en 2012

Redox nanoparticles as a novel treatment approach for inflammation and fibrosis associated with nonalcoholic steatohepatitis.

artículo científico publicado en 2015

Redox nanoparticles inhibit curcumin oxidative degradation and enhance its therapeutic effect on prostate cancer.

artículo científico publicado en 2015

Redox-active injectable gel using polyion complex to achieve sustained release of exenatide and enhance therapeutic efficacy for the treatment of type 2 diabetes

scientific article published on 19 March 2019

Redox-active injectable gel using thermo-responsive nanoscale polyion complex flower micelle for noninvasive treatment of local inflammation.

artículo científico publicado en 2013

Regulation of lysozyme activity based on thermotolerant protein/smart polymer complex formation

artículo científico publicado en 2009

Self-assembled polydopamine nanoparticles improve treatment in Parkinson's disease model mice and suppress dopamine-induced dyskinesia

scientific article published on 05 April 2020

Silica-installed redox nanoparticles for novel oral nanotherapeutics - improvement in intestinal delivery with anti-inflammatory effects

scientific article published on 23 June 2014

Simple solid-phase synthesis and biological properties of carbohydrate-oligonucleotide conjugates modified at the 3'-terminus

artículo científico publicado en 2010

Smart polyion complex micelles for targeted intracellular delivery of PEGylated antisense oligonucleotides containing acid-labile linkages.

artículo científico publicado en 2005

Smart polymeric micelles as nanocarriers for oligonucleotides and siRNA delivery

artículo científico publicado en 2005

Smart siRNA Delivery Systems Based on Polymeric Nanoassemblies and Nanoparticles ⬇️

artículo científico publicado el 1 de septiembre de 2010

Specific accumulation of orally administered redox nanotherapeutics in the inflamed colon reducing inflammation with dose-response efficacy

artículo científico publicado en 2015

Stimuli-responsive smart nanogels for cancer diagnostics and therapy

artículo científico publicado en 2010

Structure and activity assay of nanozymes prepared by the coimmobilization of practically useful enzymes and hydrophilic block copolymers on gold nanoparticles

artículo científico publicado en 2008

Studies on the adsorption property and structure of polyamine-ended poly(ethylene glycol) derivatives on a gold surface by surface plasmon resonance and angle-resolved X-ray photoelectron spectroscopy

artículo científico publicado en 2009

Sulfobetaine-terminated PEG improves the qualities of an immunosensing surface

artículo científico publicado en 2014

Suppression of NSAID-induced small intestinal inflammation by orally administered redox nanoparticles.

artículo científico publicado en 2013

Synthesis and evaluation of the functional oligonucleotides-PEG conjugates

artículo científico publicado en 2004

Synthesis and in vitro and in vivo evaluations of poly(ethylene glycol)-block-poly(4-vinylbenzylphosphonate) magnetic nanoparticles containing doxorubicin as a potential targeted drug delivery system

artículo científico publicado en 2014

Synthesis of heterotelechelic poly(ethylene glycol) derivatives having alpha-benzaldehyde and omega-pyridyl disulfide groups by ring opening polymerization of ethylene oxide using 4-(diethoxymethyl)benzyl alkoxide as a novel initiator

artículo científico publicado en 2004

Synthesis of poly[N-isopropylacrylamide-g-poly(ethylene glycol)] with a reactive group at the poly(ethylene glycol) end and its thermosensitive self-assembling character

Systemic delivery of siRNA to tumors using a lipid nanoparticle containing a tumor-specific cleavable PEG-lipid.

artículo científico publicado en 2011

TEMPOL protects human neuroblastoma SH-SY5Y cells against β-amyloid-induced cell toxicity

artículo científico publicado en 2010

Targeting and Treatment of Tumor Hypoxia by Newly Designed Prodrug Possessing High Permeability in Solid Tumors

artículo científico publicado en 2016

The ROS scavenging and renal protective effects of pH-responsive nitroxide radical-containing nanoparticles.

artículo científico publicado en 2011

The behavior of ROS-scavenging nanoparticles in blood.

artículo científico publicado en 2014

The use of nitroxide radical-containing nanoparticles coupled with piperine to protect neuroblastoma SH-SY5Y cells from Aβ-induced oxidative stress

artículo científico publicado en 2011

Thermal characterization of poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles based on pyrene excimer formation

artículo científico publicado en 2004

Tumor growth suppression by gadolinium-neutron capture therapy using gadolinium-entrapped liposome as gadolinium delivery agent ⬇️

artículo científico publicado el 26 de diciembre de 2012

Two-dimensional multiarray formation of hepatocyte spheroids on a microfabricated PEG-brush surface

artículo científico publicado en 2004

Use of boron cluster-containing redox nanoparticles with ROS scavenging ability in boron neutron capture therapy to achieve high therapeutic efficiency and low adverse effects

artículo científico publicado en 2016

pH-responsive oligodeoxynucleotide (ODN)-poly(ethylene glycol) conjugate through acid-labile beta-thiopropionate linkage: preparation and polyion complex micelle formation

artículo científico publicado en 2003

pH-responsive three-layered PEGylated polyplex micelle based on a lactosylated ABC triblock copolymer as a targetable and endosome-disruptive nonviral gene vector

artículo científico publicado en 2006

pH-sensitive radical-containing-nanoparticle (RNP) for the L-band-EPR imaging of low pH circumstances.

artículo científico publicado en 2009

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