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A case with life-threatening secondary sclerosing cholangitis caused by nivolumab

artículo científico publicado en 2020

A nonsynonymous polymorphism in semaphorin 3A as a risk factor for human unexplained cardiac arrest with documented ventricular fibrillation

artículo científico publicado en 2013

A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections.

artículo científico publicado en 2013

A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.

artículo científico publicado en 2010

A translational study of resistance emergence using sequential direct-acting antiviral agents for hepatitis C using ultra-deep sequencing.

artículo científico publicado en 2013

Abatacept treatment for patients with severe acute hepatitis caused by hepatitis B virus infection - Pilot study

artículo científico publicado en 2020

Accumulation of refractory factors for pegylated interferon plus ribavirin therapy in older female patients with chronic hepatitis C.

artículo científico publicado en 2010

Advanced liver fibrosis effects on the response to sofosbuvir-based antiviral therapies for chronic hepatitis C

artículo científico publicado en 2018

Amino acid substitutions in core and NS5A regions of the HCV genome can predict virological decrease with pegylated interferon plus ribavirin therapy

artículo científico publicado en 2010

Animal model for study of human hepatitis viruses

scientific article published on January 2011

Antiviral effects of anti-HBs immunoglobulin and vaccine on HBs antigen seroclearance for chronic hepatitis B infection

artículo científico publicado en 2016

Association between variants in the interferon lambda 4 locus and substitutions in the hepatitis C virus non-structural protein 5A.

artículo científico publicado en 2015

CTL-associated and NK cell-associated immune responses induce different HBV DNA reduction patterns in chronic hepatitis B patients

article

Chromosomal Abnormalities in Human Lymphocytes after Computed Tomography Scan Procedure

scientific article published on 24 July 2018

Circulating Tumor DNA Analysis for Liver Cancers and Its Usefulness as a Liquid Biopsy

artículo científico publicado en 2015

Circulating cytokines and angiogenic factors based signature associated with the relative dose intensity during treatment in patients with advanced hepatocellular carcinoma receiving lenvatinib

artículo científico publicado en 2020

Circulating microRNA-22 correlates with microRNA-122 and represents viral replication and liver injury in patients with chronic hepatitis B.

artículo científico publicado en 2013

Clinical Usefulness of Serum Autotaxin for Early Prediction of Relapse in Male Patients with Type 1 Autoimmune Pancreatitis

artículo científico publicado en 2020

Combination therapies with NS5A, NS3 and NS5B inhibitors on different genotypes of hepatitis C virus in human hepatocyte chimeric mice

artículo científico publicado en 2013

Combination therapies with daclatasvir and asunaprevir on NS3-D168 mutated HCV in human hepatocyte chimeric mice.

artículo científico publicado en 2015

Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy.

artículo científico publicado en 2011

Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients.

artículo científico publicado en 2010

Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice

artículo científico publicado en 2019

Correction to: Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradication therapy

scientific article published on 19 April 2020

Correction: Reduction of hepatitis B surface antigen in sequential versus add-on pegylated interferon to nucleoside/nucleotide analogue therapy in HBe-antigen-negative chronic hepatitis B patients: a pilot study

scientific article published on 01 January 2019

Daclatasvir and asunaprevir treatment improves liver function parameters and reduces liver fibrosis markers in chronic hepatitis C patients

artículo científico publicado en 2015

Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice

artículo científico publicado en 2013

Development of a Novel Site-Specific Pegylated Interferon Beta for Antiviral Therapy of Chronic Hepatitis B Virus

artículo científico publicado en 2017

Differences in serum microRNA profiles in hepatitis B and C virus infection.

artículo científico publicado en 2014

Early events in hepatitis B virus infection: From the cell surface to the nucleus

artículo científico

Effect of prolonged administration of pegylated interferon/ribavirin therapy in genotypes 2a and 2b: propensity score-matched analysis

artículo científico publicado en 2015

Effect of tenofovir disoproxil fumarate on drug-resistant HBV clones

artículo científico publicado en 2015

Effect of vitamin D supplementation on pegylated interferon/ribavirin therapy for chronic hepatitis C genotype 1b: a randomized controlled trial

artículo científico publicado en 2013

Effects of ITPA polymorphism on decrease of hemoglobin during simeprevir, peg-interferon, and ribavirin combination treatment for chronic hepatitis C.

artículo científico publicado en 2016

Effects of hepatitis B virus infection on the interferon response in immunodeficient human hepatocyte chimeric mice

artículo científico publicado en 2011

Efficacy and safety of daclatasvir plus asunaprevir therapy for chronic hepatitis C patients with renal dysfunction.

artículo científico publicado en 2016

Efficacy and safety of ledipasvir/sofosbuvir with ribavirin in chronic hepatitis C patients who failed daclatasvir/asunaprevir therapy: pilot study

artículo científico publicado en 2017

Efficacy of Lusutrombopag for Thrombocytopenia in Patients with Chronic Liver Disease Scheduled to Undergo Invasive Procedures

artículo científico publicado en 2020

Efficacy of glecaprevir and pibrentasvir treatment for genotype 1b hepatitis C virus drug resistance-associated variants in humanized mice

scientific article published on 14 June 2019

Elimination of HCV via a non-ISG-mediated mechanism by vaniprevir and BMS-788329 combination therapy in human hepatocyte chimeric mice

artículo científico publicado en 2015

Elimination of hepatitis C virus by short term NS3-4A and NS5B inhibitor combination therapy in human hepatocyte chimeric mice

artículo científico publicado en 2010

Emergence of drug resistance-associated variants and changes in serum lipid profiles in sofosbuvir plus ledipasvir-treated chronic hepatitis C patients.

artículo científico publicado en 2017

Emergence of resistant variants detected by ultra-deep sequencing after asunaprevir and daclatasvir combination therapy in patients infected with hepatitis C virus genotype 1.

artículo científico publicado en 2014

Emerging treatments for chronic hepatitis C.

artículo científico publicado en 2014

Endoplasmic reticulum-mediated induction of interleukin-8 occurs by hepatitis B virus infection and contributes to suppression of interferon responsiveness in human hepatocytes

artículo científico publicado en 2018

Erratum to: Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy

artículo científico publicado en 2018

Factors predictive of sustained virological response following 72 weeks of combination therapy for genotype 1b hepatitis C.

artículo científico publicado en 2011

Genetics of IL28B and HCV--response to infection and treatment

artículo científico

Genomic Characterization of Non-Invasive Differentiated-Type Gastric Cancer in the Japanese Population

artículo científico publicado en 2020

Genomic characterization of early-stage esophageal squamous cell carcinoma in a Japanese population

artículo científico publicado en 2019

Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradiation therapy

artículo científico publicado en 2019

HBV culture and infectious systems

artículo científico publicado en 2016

HBx protein is indispensable for development of viraemia in human hepatocyte chimeric mice.

artículo científico publicado en 2010

HCV Drug Resistance Challenges in Japan: The Role of Pre-Existing Variants and Emerging Resistant Strains in Direct Acting Antiviral Therapy

artículo científico publicado en 2015

HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy

artículo científico publicado en 2010

HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study

artículo científico publicado en 2013

Hepatitis B virus-specific miRNAs and Argonaute2 play a role in the viral life cycle

artículo científico publicado en 2012

Hepatitis C virus dynamics and cellular gene expression in uPA-SCID chimeric mice with humanized livers during intravenous silibinin monotherapy

artículo científico publicado en 2016

Hepatitis C virus infection suppresses the interferon response in the liver of the human hepatocyte chimeric mouse

artículo científico publicado en 2011

Hepatitis C virus: How genetic variability affects pathobiology of disease

artículo científico publicado en 2011

Hepatocellular carcinoma: towards personalized medicine.

artículo científico

Human Cytotoxic T Lymphocyte-Mediated Acute Liver Failure and Rescue by Immunoglobulin in Human Hepatocyte Transplant TK-NOG Mice

artículo científico publicado en 2015

Human microRNA hsa-miR-1231 suppresses hepatitis B virus replication by targeting core mRNA.

artículo científico publicado en 2014

IFNL4 polymorphism effects on outcome of simeprevir, peginterferon, and ribavirin therapy for older patients with genotype 1 chronic hepatitis C.

artículo científico publicado en 2016

IFNL4/IL-28B haplotype structure and its impact on susceptibility to hepatitis C virus and treatment response in the Japanese population

artículo científico publicado en 2014

IL-28B predicts response to chronic hepatitis C therapy--fine-mapping and replication study in Asian populations.

artículo científico publicado en 2011

IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy.

artículo científico publicado en 2011

IL28B but not ITPA polymorphism is predictive of response to pegylated interferon, ribavirin, and telaprevir triple therapy in patients with genotype 1 hepatitis C

artículo científico publicado en 2011

IL28B polymorphism is associated with fatty change in the liver of chronic hepatitis C patients.

artículo científico publicado en 2012

ITPA polymorphism affects ribavirin-induced anemia and outcomes of therapy--a genome-wide study of Japanese HCV virus patients.

artículo científico publicado en 2010

ITPA polymorphism effects on decrease of hemoglobin during sofosbuvir and ribavirin combination treatment for chronic hepatitis C.

artículo científico publicado en 2016

Identification of novel HCV deletion mutants in chronic hepatitis C patients

artículo científico publicado en 2012

Impact of interleukin-28B genotype on in vitro and in vivo systems of hepatitis C virus replication

artículo científico publicado en 2012

Impact of viral amino acid substitutions and host interleukin-28b polymorphism on replication and susceptibility to interferon of hepatitis C virus

artículo científico publicado en 2011

Impact of viral eradication by DAAs on the risk of HCC development, prognosis and portal hypertension in HCV-related compensated cirrhosis patients

artículo científico publicado en 2020

Importance of serum concentration of adefovir for Lamivudine-adefovir combination therapy in patients with lamivudine-resistant chronic hepatitis B.

artículo científico publicado en 2010

Improvement of renal dysfunction in a patient with hepatitis C virus-related liver cirrhosis by daclatasvir and asunaprevir combination therapy: A case report.

artículo científico publicado en 2015

Interferon alpha treatment stimulates interferon gamma expression in type I NKT cells and enhances their antiviral effect against hepatitis C virus

artículo científico publicado en 2017

Interferon lambda 4 polymorphism affects on outcome of telaprevir, pegylated interferon and ribavirin combination therapy for chronic hepatitis C.

artículo científico publicado en 2014

Interferon stimulated genes and innate immune activation following infection with hepatitis B and C viruses

artículo científico publicado en 2016

Interleukin-28B polymorphisms and hepatitis C virus clearance.

artículo científico publicado en 2013

Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state.

artículo científico publicado en 2011

Involvement of Porphyromonas gingivalis in the progression of non-alcoholic fatty liver disease.

artículo científico publicado en 2017

Limitations of daclatasvir/asunaprevir plus beclabuvir treatment in cases of NS5A inhibitor treatment failure

artículo científico publicado en 2018

Liver fibrosis assessments using FibroScan, virtual-touch tissue quantification, the FIB-4 index, and mac-2 binding protein glycosylation isomer levels compared with pathological findings of liver resection specimens in patients with hepatitis C inf

scientific article published on 25 September 2020

Long term persistence of NS5A inhibitor-resistant hepatitis C virus in patients who failed daclatasvir and asunaprevir therapy

artículo científico publicado en 2015

ME3738 enhances the effect of interferon and inhibits hepatitis C virus replication both in vitro and in vivo.

artículo científico publicado en 2010

Management of HCV patients in cases of direct-acting antiviral failure

scientific article published on 08 August 2019

MicroRNAs as Biomarkers for Liver Disease and Hepatocellular Carcinoma

artículo científico publicado en 2016

Molecular Mechanisms of Hepatocarcinogenesis Following Sustained Virological Response in Patients with Chronic Hepatitis C Virus Infection

scientific article published in 2018

New insight into the enhanced effect of pegylated interferon-α.

artículo científico publicado en 2014

Novel robust in vitro hepatitis B virus infection model using fresh human hepatocytes isolated from humanized mice

artículo científico publicado en 2015

Optimizing triple therapy and IFN/RBV-free regimens for hepatitis C virus infection

artículo científico publicado en 2014

PNPLA3 and HLA-DQB1 polymorphisms are associated with hepatocellular carcinoma after hepatitis C virus eradication

artículo científico publicado en 2020

Pan-genotypic cell culture system for propagation of hepatitis C virus clinical isolates

artículo científico publicado en 2016

Persistent Loss of Hepatitis B Virus Markers in Serum without Cellular Immunity by Combination of Peginterferon and Entecavir Therapy in Humanized Mice

artículo científico publicado en 2017

Prediction of response to peginterferon-alfa-2b plus ribavirin therapy in Japanese patients infected with hepatitis C virus genotype 1b.

artículo científico publicado en 2011

Predictive value of the IFNL4 polymorphism on outcome of telaprevir, peginterferon, and ribavirin therapy for older patients with genotype 1b chronic hepatitis C.

artículo científico publicado en 2013

Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.

artículo científico publicado en 2010

Prevalence of NS5A resistance associated variants in NS5A inhibitor treatment failures and an effective treatment for NS5A-P32 deleted hepatitis C virus in humanized mice

artículo científico publicado en 2018

Protease Inhibitor Resistance Remains Even After Mutant Strains Become Undetectable by Deep Sequencing

artículo científico publicado en 2016

Pruritus in patients with chronic liver disease and serum autotaxin levels in patients with primary biliary cholangitis

artículo científico publicado en 2019

Publisher Correction: Regulation of the Hepatitis B virus replication and gene expression by the multi-functional protein TARDBP

artículo científico publicado en 2020

Rapid emergence of telaprevir resistant hepatitis C virus strain from wildtype clone in vivo

artículo científico publicado en 2011

Rapid, Sensitive, and Accurate Evaluation of Drug Resistant Mutant (NS5A-Y93H) Strain Frequency in Genotype 1b HCV by Invader Assay

artículo científico publicado en 2015

Real-word efficacy of sofosbuvir, velpatasvir plus ribavirin therapy for chronic hepatitis patients who failed to prior DAA therapy with NS5A-P32 deletion mutated HCV infection

artículo científico publicado en 2020

Real-world efficacy and safety of daclatasvir and asunaprevir therapy for hepatitis C virus-infected cirrhosis patients

artículo científico publicado en 2016

Real-world efficacy of glecaprevir plus pibrentasvir for chronic hepatitis C patient with previous direct-acting antiviral therapy failures

scientific article published on 17 October 2018

Real-world efficacy of sofosbuvir plus velpatasvir therapy for patients with hepatitis C virus-related decompensated cirrhosis

scientific article published on 11 September 2020

Reduction of hepatitis B surface antigen in sequential versus add-on pegylated interferon to nucleoside/nucleotide analogue therapy in HBe-antigen-negative chronic hepatitis B patients: a pilot study

artículo científico publicado en 2018

Regression of Idiopathic Thrombocytopenic Purpura in a Patient With Eradication of Hepatitis C Virus by Direct-Acting Antivirals

scientific article published on 11 October 2019

Regulation of the Hepatitis B virus replication and gene expression by the multi-functional protein TARDBP

artículo científico publicado en 2019

Response to "treatment guidelines for HCV genotype 1: mono for low, triple for high, and dual for 'middle'?"

artículo científico publicado en 2013

Retrospective Identification of Herpes Simplex 2 Virus-Associated Acute Liver Failure in an Immunocompetent Patient Detected Using Whole Transcriptome Shotgun Sequencing.

artículo científico publicado en 2017

Ribavirin dose reduction during telaprevir/ribavirin/peg-interferon therapy overcomes the effect of the ITPA gene polymorphism.

artículo científico publicado en 2014

Ribavirin induces hepatitis C virus genome mutations in chronic hepatitis patients who failed to respond to prior daclatasvir plus asunaprevir therapy

scientific article published on 16 October 2019

Risk factors for histological progression of non-alcoholic steatohepatitis analyzed from repeated biopsy cases

scientific article published on 02 January 2020

Safety and efficacy of dual therapy with daclatasvir and asunaprevir for older patients with chronic hepatitis C.

artículo científico publicado en 2016

Serum HBV RNA and HBeAg are useful markers for the safe discontinuation of nucleotide analogue treatments in chronic hepatitis B patients.

artículo científico publicado en 2013

Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy.

artículo científico publicado en 2017

Severe necroinflammatory reaction caused by natural killer cell-mediated Fas/Fas ligand interaction and dendritic cells in human hepatocyte chimeric mouse.

artículo científico publicado en 2012

Signal activation of hepatitis B virus-related hepatocarcinogenesis by upregulation of SUV39h1

artículo científico publicado en 2020

Successful retreatment with 12 weeks of glecaprevir and pibrentasvir for a genotype 2a HCV-infected hemodialysis patient who failed to respond to 8 weeks of prior glecaprevir and pibrentasvir therapy

scientific article published on 28 August 2019

The Role of Lipids in Hepatocellular Carcinoma

artículo científico publicado en 2019

The association between serum cytokine and chemokine levels and antiviral response by entecavir treatment in chronic hepatitis B patients

artículo científico publicado en 2017

The practical management of chronic hepatitis C infection in Japan - dual therapy of daclatasvir + asunaprevir

artículo científico publicado en 2016

The relationship between HBcrAg and HBV reinfection in HBV related post-liver transplantation patients

artículo científico publicado en 2016

The risks of hepatocellular carcinoma development after HCV eradication are similar between patients treated with peg-interferon plus ribavirin and direct-acting antiviral therapy.

artículo científico publicado en 2017

Three patients treated with daclatasvir and asunaprevir for recurrent hepatitis C after liver transplantation: Case report

artículo científico publicado en 2015

Three patients treated with sofosbuvir plus ledipasvir for recurrent hepatitis C after liver transplantation

artículo científico publicado en 2017

Toward the establishment of a prediction system for the personalized treatment of chronic hepatitis C.

artículo científico publicado en 2011

Treatment of HCV patients on hemodialysis with daclatasvir and asunaprevir

artículo científico publicado en 2016

Treatment of chronic hepatitis C virus infection in Japan: update on therapy and guidelines

artículo científico publicado en 2012

Tumor Fibroblast Growth Factor Receptor 4 Level Predicts the Efficacy of Lenvatinib in Patients With Advanced Hepatocellular Carcinoma

scientific article published on 01 May 2020

Two patients treated with simeprevir plus pegylated-interferon and ribavirin triple therapy for recurrent hepatitis C after living donor liver transplantation: case report

artículo científico publicado en 2015

Ultradeep sequencing study of chronic hepatitis C virus genotype 1 infection in patients treated with daclatasvir, peginterferon, and ribavirin.

artículo científico publicado en 2014

Usefulness of humanized cDNA-uPA/SCID mice for the study of hepatitis B virus and hepatitis C virus virology

artículo científico publicado en 2017

Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers

scientific journal article

Wisteria floribunda agglutinin positive Mac-2-binding protein level increases in patients with acute liver injury

artículo científico publicado en 2017

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