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A high-stringency blueprint of the human proteome

scientific article published on 16 October 2020

A myoglobin variant with a polar substitution in a conserved hydrophobic cluster in the heme binding pocket

artículo científico publicado el 15 de agosto de 1997

Advances in Identifying and Characterizing the Human Proteome

scientific article published on 01 December 2019

An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient

artículo científico publicado en 2019

C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease.

artículo científico publicado en 2018

CLIPPER: an add-on to the Trans-Proteomic Pipeline for the automated analysis of TAILS N-terminomics data

artículo científico publicado el 1 de diciembre de 2012

Deep Profiling of the Cleavage Specificity and Human Substrates of Snake Venom Metalloprotease HF3 by Proteomic Identification of Cleavage Site Specificity (PICS) Using Proteome Derived Peptide Libraries and Terminal Amine Isotopic Labeling of Subst

artículo científico publicado en 2019

Discovery of a proteolytic flagellin family in diverse bacterial phyla that assembles enzymatically active flagella

artículo científico publicado en 2017

Expression of matrix metalloproteinases (MMP-1 and -2) and their inhibitors (TIMP-1, -2 and -3) in oral lichen planus, dysplasia, squamous cell carcinoma and lymph node metastasis

artículo científico publicado el 1 de junio de 1998

Global Profiling of Proteolysis from the Mitochondrial Amino Terminome during Early Intrinsic Apoptosis Prior to Caspase-3 Activation

scientific article published on 29 October 2018

Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction.

artículo científico publicado en 2018

Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases

artículo científico publicado en 2019

Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)-A CleavEx Based Analysis

artículo científico publicado en 2020

Launching the C-HPP pilot project for functional characterization of identified proteins with no known function

scientific article published on 29 November 2018

MMP8 increases tongue carcinoma cell-cell adhesion and diminishes migration via cleavage of anti-adhesive FXYD5

artículo científico publicado en 2021

Master Sculptor at Work: Enteropathogenic Escherichia coli Infection Uniquely Modifies Mitochondrial Proteolysis during Its Control of Human Cell Death

scientific article published on 02 June 2020

Matrix metalloproteinases in the CNS: interferons get nervous

scientific article published on 04 June 2019

Novel Human Aminopeptidase N Inhibitors: Discovery and Optimization of Subsite Binding Interactions

scientific article published on 18 July 2019

Progress on Identifying and Characterizing the Human Proteome: 2018 Metrics from the HUPO Human Proteome Project

artículo científico publicado en 2018

Progress on Identifying and Characterizing the Human Proteome: 2019 Metrics from the HUPO Human Proteome Project

scientific article published on 13 September 2019

Protein TAILS: when termini tell tales of proteolysis and function

artículo científico publicado el 6 de enero de 2013

Proteomic and N-Terminomic TAILS Analyses of Human Alveolar Bone Proteins: Improved Protein Extraction Methodology and LysargiNase Digestion Strategies Increase Proteome Coverage and Missing Protein Identification

artículo científico publicado en 2019

Quantitative proteomics and terminomics to elucidate the role of ubiquitination and proteolysis in adaptive immunity

artículo científico publicado en 2016

Sharpening Host Defenses during Infection: Proteases Cut to the Chase

artículo científico publicado en 2017

The HUPO High-Stringency Inventory of Humanity's Shared Human Proteome Revealed

artículo científico publicado en 2020

The Human Proteome Organization Chromosome 6 Consortium: Integrating chromosome-centric and biology/disease driven strategies

artículo científico publicado el 8 de agosto de 2013

The Human Proteome: 90% in the Light, 10% on the Dark Side

artículo científico publicado en 2020

The Involvement of the Fibronectin Type II-like Modules of Human Gelatinase A in Cell Surface Localization and Activation

artículo científico publicado el 7 de agosto de 1998

TopFIND 2.0--linking protein termini with proteolytic processing and modifications altering protein function

artículo científico publicado el 18 de noviembre de 2011

Toward Completion of the Human Proteome Parts List: Progress Uncovering Proteins That Are Missing or Have Unknown Function and Developing Analytical Methods

artículo científico publicado en 2018