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2D-ELDOR study of heterogeneity and domain structure changes in plasma membrane vesicles upon cross-linking of receptors.

artículo científico publicado en 2011

A basic sequence in STIM1 promotes Ca2+ influx by interacting with the C-terminal acidic coiled coil of Orai1.

artículo científico publicado en 2010

A guanine nucleotide-binding protein participates in IgE receptor-mediated activation of endogenous and reconstituted phospholipase A2 in a permeabilized cell system

scientific article published on 01 January 1990

A lipid raft environment enhances Lyn kinase activity by protecting the active site tyrosine from dephosphorylation

scientific journal article

A nanosecond fluorescence depolarization study on the segmental flexibility of receptor-bound immunoglobulin E

artículo científico publicado en 1990

A novel fluorescence-based biosynthetic trafficking method provides pharmacologic evidence that PI4-kinase IIIα is important for protein trafficking from the endoplasmic reticulum to the plasma membrane

artículo científico publicado en 2015

Activated Cdc42/Rac reconstitutes Fcepsilon RI-mediated Ca2+ mobilization and degranulation in mutant RBL mast cells

artículo científico publicado en 2001

Activation of Cdc42 is necessary for sustained oscillations of Ca2+ and PIP2 stimulated by antigen in RBL mast cells

artículo científico publicado en 2014

Aggregation of IgE-receptor complexes on rat basophilic leukemia cells does not change the intrinsic affinity but can alter the kinetics of the ligand-IgE interaction

artículo científico publicado el 16 de junio de 1992

Alteration of lipid composition modulates Fc epsilon RI signaling in RBL-2H3 cells

artículo científico publicado en 1995

Altered patterns of tyrosine phosphorylation and Syk activation for sterically restricted cyclic dimers of IgE-Fc epsilonRI.

artículo científico publicado en 1997

An Array of Planar Apertures for Near-Field Fluorescence Correlation Spectroscopy ⬇️

artículo científico publicado el 6 de abril de 2011

An Interaction Library for the FcεRI Signaling Network

artículo científico publicado en 2014

Antigen-decorated shell cross-linked nanoparticles: synthesis, characterization, and antibody interactions

artículo científico publicado en 2005

Antigen-mediated IGE receptor aggregation and signaling: a window on cell surface structure and dynamics

artículo científico publicado en 1996

Antigen-stimulated trafficking from the recycling compartment to the plasma membrane in RBL mast cells

artículo científico publicado en 2003

Antigen-triggered membrane potential changes in IgE-sensitized rat basophilic leukemia cells: evidence for a repolarizing response that is important in the stimulation of cellular degranulation

artículo científico publicado en 1989

Basic Amino Acids Within the Juxtamembrane Domain of the Epidermal Growth Factor Receptor Regulate Receptor Dimerization and Auto-phosphorylation

artículo científico publicado en 2020

Beyond Media Composition: Cell Plasma Membrane Disruptions by Graphene Oxide

artículo científico publicado en 2017

Binding mechanisms of PEGylated ligands reveal multiple effects of the PEG scaffold

artículo científico publicado en 2007

Bivalent binding of an anti-CD3 antibody to Jurkat cells induces association of the T cell receptor complex with the cytoskeleton

scientific article published on 01 August 1989

Bivalent ligand dissociation kinetics from receptor-bound immunoglobulin E: evidence for a time-dependent increase in ligand rebinding at the cell surface ⬇️

artículo científico publicado el 5 de marzo de 1991

Bivalent ligands with rigid double-stranded DNA spacers reveal structural constraints on signaling by Fc epsilon RI.

artículo científico publicado en 2002

Bright and stable core-shell fluorescent silica nanoparticles.

artículo científico publicado en 2005

Bringing light to ER contacts and a new phase in organelle communication

scientific article published on 28 April 2020

Ca2+ waves initiate antigen-stimulated Ca2+ responses in mast cells

artículo científico publicado en 2009

Cell investigation of nanostructures: zero-mode waveguides for plasma membrane studies with single molecule resolution

article published in 2007

Cellular responses to patterned poly(acrylic acid) brushes.

artículo científico publicado en 2011

Characterization of increased K+ permeability associated with the stimulation of receptors for immunoglobulin E on rat basophilic leukemia cells ⬇️

artículo científico publicado el 15 de agosto de 1991

Characterization of model antigens composed of biotinylated haptens bound to avidin

scientific article published on 01 February 1990

Characterization of new rat anti-mouse IgE monoclonals and their use along with chimeric IgE to further define the site that interacts with Fc epsilon RII and Fc epsilon RI

scientific article published on 01 October 1991

Cholera toxin increases the rate of antigen-stimulated calcium influx in rat basophilic leukemia cells

scientific article published on 01 December 1988

Clustering, mobility, and triggering activity of small oligomers of immunoglobulin E on rat basophilic leukemia cells

artículo científico publicado en 1986

Coexisting domains in the plasma membranes of live cells characterized by spin-label ESR spectroscopy

artículo científico publicado en 2006

Compartmentalized activation of the high affinity immunoglobulin E receptor within membrane domains

artículo científico publicado en 1997

Competition between solution and cell surface receptors for ligand. Dissociation of hapten bound to surface antibody in the presence of solution antibody

artículo científico publicado en 1989

Computation of a Theoretical Membrane Phase Diagram and the Role of Phase in Lipid-Raft-Mediated Protein Organization

artículo científico publicado en 2018

Conformations of IgE bound to its receptor Fc epsilon RI and in solution

artículo científico publicado en 1991

Constrained diffusion or immobile fraction on cell surfaces: a new interpretation

artículo científico publicado en 1996

Core/Shell fluorescent silica nanoparticles for chemical sensing: towards single-particle laboratories

artículo científico publicado en 2006

Correlation functions quantify super-resolution images and estimate apparent clustering due to over-counting

artículo científico publicado en 2012

Cover Picture: Core/Shell Fluorescent Silica Nanoparticles for Chemical Sensing: Towards Single-Particle Laboratories (Small 6/2006)

Critical fluctuations in plasma membrane vesicles.

artículo científico publicado en 2008

Critical role for cholesterol in Lyn-mediated tyrosine phosphorylation of FcepsilonRI and their association with detergent-resistant membranes

artículo científico publicado en 1999

Cross-correlation analysis of inner-leaflet-anchored green fluorescent protein co-redistributed with IgE receptors and outer leaflet lipid raft components

artículo científico publicado en 2001

Cross-linking of IgE-receptor complexes at the cell surface: a fluorescence method for studying the binding of monovalent and bivalent haptens to IgE.

artículo científico publicado en 1986

Cross-linking of IgE-receptor complexes at the cell surface: synthesis and characterization of a long bivalent hapten that is capable of triggering mast cells and rat basophilic leukemia cells

artículo científico publicado en 1986

Cross-linking of IgE-receptor complexes by rigid bivalent antigens greater than 200 A in length triggers cellular degranulation

artículo científico publicado en 1988

Cross-linking of immunoglobulin E-receptor complexes induces their interaction with the cytoskeleton of rat basophilic leukemia cells

artículo científico publicado en 1986

Cross-linking of receptor-bound IgE to aggregates larger than dimers leads to rapid immobilization

artículo científico publicado en 1986

Crosslinking a lipid raft component triggers liquid ordered-liquid disordered phase separation in model plasma membranes

artículo científico publicado en 2005

Differential targeting of secretory lysosomes and recycling endosomes in mast cells revealed by patterned antigen arrays.

artículo científico publicado en 2007

Dinitrophenyl ligand substrates and their application to immunosensors.

artículo científico publicado en 2006

Disruption of lipid order by short-chain ceramides correlates with inhibition of phospholipase D and downstream signaling by FcepsilonRI.

artículo científico publicado en 2003

Dissociation kinetics of bivalent ligand-immunoglobulin E aggregates in solution

artículo científico publicado en 1991

Distinct stages of stimulated FcεRI receptor clustering and immobilization are identified through superresolution imaging.

artículo científico publicado en 2013

Dynamic conformations compared for IgE and IgG1 in solution and bound to receptors

artículo científico publicado el 25 de agosto de 1992

Effects of subunit mutation on the rotational dynamics of Fc epsilon RI, the high affinity receptor for IgE, in transfected cells

artículo científico publicado en 1995

Electron spin resonance characterization of liquid ordered phase of detergent-resistant membranes from RBL-2H3 cells

artículo científico publicado en 1999

Electrospray mass spectra from protein electroeluted from sodium dodecylsulfate polyacrylamide gel electrophoresis gels

artículo científico publicado en 1999

Evidence supporting a role for microfilaments in regulating the coupling between poorly dissociable IgE-Fc epsilonRI aggregates downstream signaling pathways

artículo científico publicado en 1997

Fc epsilon RI and the T cell receptor for antigen activate similar signalling pathways in T cell-RBL cell hybrids

artículo científico publicado en 1993

Fc epsilon RI-mediated association of 6-micron beads with RBL-2H3 mast cells results in exclusion of signaling proteins from the forming phagosome and abrogation of normal downstream signaling

artículo científico publicado en 1996

Fc epsilon RI-mediated recruitment of p53/56lyn to detergent-resistant membrane domains accompanies cellular signaling

artículo científico publicado en 1995

Fc(epsilon)RI as a paradigm for a lipid raft-dependent receptor in hematopoietic cells

artículo científico publicado en 2001

FcεRI Signaling in Specialized Membrane Domains

Fluorescence anisotropy measurements of lipid order in plasma membranes and lipid rafts from RBL-2H3 mast cells

artículo científico publicado en 2001

Fluorescence resonance energy transfer between lipid probes detects nanoscopic heterogeneity in the plasma membrane of live cells

artículo científico publicado en 2007

Fluorescence resonance energy transfer reveals interleukin (IL)-1-dependent aggregation of IL-1 type I receptors that correlates with receptor activation

scientific article published on 01 November 1995

Fluorescent core-shell silica nanoparticles: an alternative radiative materials platform

Focal adhesion proteins connect IgE receptors to the cytoskeleton as revealed by micropatterned ligand arrays

artículo científico publicado en 2008

Functional nanoscale coupling of Lyn kinase with IgE-FcεRI is restricted by the actin cytoskeleton in early antigen-stimulated signaling

artículo científico publicado en 2016

Functionalized surface arrays for spatial targeting of immune cell signaling

artículo científico publicado en 2006

Generalized platform for antibody detection using the antibody catalyzed water oxidation pathway

artículo científico publicado en 2014

Graphene Oxide Nanosheets Stimulate Ruffling and Shedding of Mammalian Cell Plasma Membranes.

artículo científico publicado en 2016

Heterogeneous Glycosylation of Immunoglobulin E Constructs Characterized by Top-Down High-Resolution 2-D Mass Spectrometry†

artículo científico publicado en 2000

Heterologous desensitization of the high affinity receptor for IgE (Fc epsilon R1) on RBL cells

artículo científico publicado en 1993

High spatial resolution observation of single-molecule dynamics in living cell membranes

artículo científico publicado en 2005

Highly Effective Poly(Ethylene Glycol) Architectures for Specific Inhibition of Immune Receptor Activation ⬇️

artículo científico publicado el 11 de noviembre de 2003

Highly aminated mesoporous silica nanoparticles with cubic pore structure

artículo científico publicado en 2010

How does the plasma membrane participate in cellular signaling by receptors for immunoglobulin E?

artículo científico publicado en 1999

IgE receptor-mediated alteration of membrane-cytoskeleton interactions revealed by mass spectrometric analysis of detergent-resistant membranes

artículo científico publicado en 2009

Imaging FCS delineates subtle heterogeneity in plasma membranes of resting mast cells

artículo científico publicado en 2020

In situ measurement of degranulation as a biosensor based on RBL-2H3 mast cells.

artículo científico publicado en 2004

Inhibitors of PI(4,5)P2 synthesis reveal dynamic regulation of IgE receptor signaling by phosphoinositides in RBL mast cells.

artículo científico publicado en 2013

Insights into immunoglobulin E receptor signaling from structurally defined ligands

artículo científico publicado en 2007

Interaction of IgE with its high-affinity receptor. Structural basis and requirements for effective cross-linking.

artículo científico publicado en 1989

Interactions between Fc(epsilon)RI and lipid raft components are regulated by the actin cytoskeleton.

artículo científico publicado en 2000

Interleukin 1 (IL-1) causes changes in lateral and rotational mobilities of IL-1 type I receptors

artículo científico publicado en 1999

Kinetics of multivalent antigen DNP-BSA binding to IgE-Fc epsilon RI in relationship to the stimulated tyrosine phosphorylation of Fc epsilon RI ⬇️

artículo científico publicado el 1 de abril de 1998

Lactoperoxidase-catalyzed iodination of the receptor for immunoglobulin E at the cytoplasmic side of the plasma membrane ⬇️

artículo científico publicado el 25 de marzo de 1984

Large-scale co-aggregation of fluorescent lipid probes with cell surface proteins

artículo científico publicado en 1994

Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles

artículo científico publicado en 2007

Lateral Diffusion of Membrane Lipid-Anchored Probes before and after Aggregation of Cell Surface IgE-Receptors†

Lipid rafts, fluid/fluid phase separation, and their relevance to plasma membrane structure and function

artículo científico publicado en 2007

Lipid segregation and IgE receptor signaling: a decade of progress

artículo científico publicado en 2005

Mapping the site of interaction between murine IgE and its high affinity receptor with chimeric Ig

artículo científico publicado en 1990

Mast Cell Activation on Patterned Lipid Bilayers of Subcellular Dimensions†

Mechanisms of epidermal growth factor receptor signaling as characterized by patterned ligand activation and mutational analysis

artículo científico publicado en 2016

Membrane organization in immunoglobulin E receptor signaling

artículo científico publicado en 1999

Membrane-bound IgE receptor complexes fused with rat basophilic leukemia cells mediate degranulation

artículo científico publicado en 1987

Microfilaments regulate the rate of exocytosis in rat basophilic leukemia cells

artículo científico publicado en 1990

Micropatterned Ligand Arrays to Study Spatial Regulation in Fc Receptor Signaling ⬇️

artículo científico publicado el 1 de enero de 2011

Molecular Templates for Bio-specific Recognition by Low-Energy Electron Beam Lithography

Molecular anatomy of the early events in STIM1 activation - oligomerization or conformational change?

artículo científico publicado en 2017

Molecular clustering of STIM1 with Orai1/CRACM1 at the plasma membrane depends dynamically on depletion of Ca2+ stores and on electrostatic interactions.

artículo científico publicado en 2008

Molecular crowding on the cell surface

scientific article published on 01 January 1988

Molecular mechanisms of spontaneous and directed mast cell motility

artículo científico publicado en 2012

Mutant RBL mast cells defective in Fc epsilon RI signaling and lipid raft biosynthesis are reconstituted by activated Rho-family GTPases

artículo científico publicado en 2000

Mutations in the polybasic juxtamembrane sequence of both plasma membrane- and endoplasmic reticulum-localized epidermal growth factor receptors confer ligand-independent cell transformation

scientific article published on 18 October 2013

Nanobiotechnology and cell biology: micro- and nanofabricated surfaces to investigate receptor-mediated signaling

artículo científico publicado en 2008

Nanodomains in early and later phases of FcɛRI signalling

artículo científico publicado en 2015

Near-field fluorescence cross-correlation spectroscopy on planar membranes.

artículo científico publicado en 2014

Non-Faradaic Electrochemical Detection of Exocytosis from Mast and Chromaffin Cells Using Floating-Gate MOS Transistors

artículo científico publicado en 2015

Oligo(ethylene glycol) containing polymer brushes as bioselective surfaces

artículo científico publicado en 2005

Ordered and disordered phases coexist in plasma membrane vesicles of RBL-2H3 mast cells. An ESR study

artículo científico publicado en 2003

Orthogonal patterning of multiple biomolecules using an organic fluorinated resist and imprint lithography.

artículo científico publicado en 2013

Patterned biofunctional poly(acrylic acid) brushes on silicon surfaces

artículo científico publicado en 2007

Polymer Brushes as Functional, Patterned Surfaces for Nanobiotechnology

artículo científico publicado en 2013

Polyunsaturated fatty acids inhibit stimulated coupling between the ER Ca(2+) sensor STIM1 and the Ca(2+) channel protein Orai1 in a process that correlates with inhibition of stimulated STIM1 oligomerization.

artículo científico publicado en 2014

Preventing nonspecific adsorption on polymer brush covered gold electrodes using a modified ATRP initiator.

artículo científico publicado en 2009

Proteolytic digestion of the beta and gamma subunits of the receptor for immunoglobulin E at the cytoplasmic face of the plasma membrane

artículo científico publicado en 1989

Quantitative Analysis of Phospholipids in Functionally Important Membrane Domains from RBL-2H3 Mast Cells Using Tandem High-Resolution Mass Spectrometry†

article

Quantitative nanoscale analysis of IgE-FcεRI clustering and coupling to early signaling proteins.

artículo científico publicado en 2012

Rab11 Regulates the Mast Cell Exocytic Response

artículo científico publicado en 2016

Real-time cross-correlation image analysis of early events in IgE receptor signaling

scientific journal article

Real-time imaging of Ca(2+) mobilization and degranulation in mast cells

artículo científico publicado en 2015

Recent evidence for common signalling mechanisms among immunoreceptors that recognize foreign antigens

artículo científico publicado en 1992

Recombinant human IgG1-murine IgE chimeric Ig. Construction, expression, and binding to human Fc gamma receptors

scientific article published on 01 December 1990

Reconstitution of regulated phosphorylation of FcepsilonRI by a lipid raft-excluded protein-tyrosine phosphatase

artículo científico publicado en 2004

Regulation of exocytosis and mitochondrial relocalization by Alpha-synuclein in a mammalian cell model

scientific article published on 27 June 2019

Response to Kang et al

scientific article published on 01 February 2011

Roles for Ca2+ Mobilization and Its Regulation in Mast Cell Functions ⬇️

artículo científico publicado el 8 de mayo de 2012

Roles for Ca2+ mobilization and its regulation in mast cell functions: recent progress

scientific article published on April 2016

Roles for SH2 and SH3 domains in Lyn kinase association with activated FcepsilonRI in RBL mast cells revealed by patterned surface analysis

artículo científico publicado en 2009

Roles for lipid heterogeneity in immunoreceptor signaling

artículo científico publicado en 2016

Rotational motion of monomeric and dimeric immunoglobulin E-receptor complexes ⬇️

artículo científico publicado el 21 de enero de 1992

STIM1 activation is regulated by a 14 amino acid sequence adjacent to the CRAC activation domain.

artículo científico publicado en 2016

Segmental flexibility of receptor-bound immunoglobulin E

artículo científico publicado en 1985

Sequestration of phosphoinositides by mutated MARCKS effector domain inhibits stimulated Ca2+mobilization and degranulation in mast cells ⬇️

artículo científico publicado el 19 de octubre de 2011

Short chain ceramides disrupt immunoreceptor signaling by inhibiting segregation of Lo from Ld Plasma membrane components

artículo científico publicado en 2018

Simultaneous cross-linking by two nontriggering bivalent ligands causes synergistic signaling of IgE Fc epsilon RI complexes.

artículo científico publicado en 1995

Small oligomers of immunoglobulin E (IgE) cause large-scale clustering of IgE receptors on the surface of rat basophilic leukemia cells ⬇️

artículo científico publicado el 1 de febrero de 1984

Spatially defined EGF receptor activation reveals an F-actin-dependent phospho-Erk signaling complex.

artículo científico publicado en 2014

Spatiotemporal resolution of mast cell granule exocytosis reveals correlation with Ca2+ wave initiation

artículo científico publicado en 2012

Sphingosine derivatives inhibit cell signaling by electrostatically neutralizing polyphosphoinositides at the plasma membrane ⬇️

artículo científico publicado el 1 de enero de 2010

Stimulated association of STIM1 and Orai1 is regulated by the balance of PtdIns(4,5)P2 between distinct membrane pools ⬇️

artículo científico publicado el 12 de julio de 2011

Stimulated release of fluorescently labeled IgE fragments that efficiently accumulate in secretory granules after endocytosis in RBL-2H3 mast cells ⬇️

artículo científico publicado el 1 de agosto de 1998

Structural aspects of the association of FcepsilonRI with detergent-resistant membranes

artículo científico publicado en 1999

Structural determinants for partitioning of lipids and proteins between coexisting fluid phases in giant plasma membrane vesicles

artículo científico publicado en 2007

Structural mapping of Fc receptor bound immunoglobulin E: proximity to the membrane surface of the antibody combining site and another site in the Fab segments

artículo científico publicado en 1985

Structural mapping of membrane-bound immunoglobulin E-receptor complexes: use of monoclonal anti-IgE antibodies to probe the conformation of receptor-bound IgE

scientific article published on 01 October 1985

Structural studies on the membrane-bound immunoglobulin E-receptor complex. 1. Characterization of large plasma membrane vesicles from rat basophilic leukemia cells and insertion of amphipathic fluorescent probes ⬇️

artículo científico publicado el 5 de julio de 1983

Sustained T cell receptor-mediated Ca2+ responses rely on dynamic engagement of receptors

artículo científico publicado en 1996

Temporally resolved interactions between antigen-stimulated IgE receptors and Lyn kinase on living cells.

artículo científico publicado en 2005

The Fc segment of IgE influences the kinetics of dissociation of a symmetrical bivalent ligand from cyclic dimeric complexes

scientific article published on 01 April 1996

The FcεRI Signaling Cascade and Integrin Trafficking Converge at Patterned Ligand Surfaces.

artículo científico publicado en 2017

The beta- and gamma-isoforms of type I PIP5K regulate distinct stages of Ca2+ signaling in mast cells

artículo científico publicado en 2009

The effect of receptor density on the forward rate constant for binding of ligands to cell surface receptors

artículo científico publicado en 1987

Timescale Separation of Positive and Negative Signaling Creates History-Dependent Responses to IgE Receptor Stimulation

artículo científico publicado en 2017

Toxoplasma gondii inhibits mast cell degranulation by suppressing phospholipase Cγ-mediated Ca2+ mobilization ⬇️

artículo científico publicado el 4 de julio de 2013

Transmembrane sequences are determinants of immunoreceptor signaling

artículo científico publicado en 2005

Trivalent ligands with rigid DNA spacers reveal structural requirements for IgE receptor signaling in RBL mast cells

artículo científico publicado en 2007

Visualization of plasma membrane compartmentalization with patterned lipid bilayers.

scholarly article

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