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A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism.

artículo científico publicado en 2016

A comparison of the properties of a Bcl-xL variant to the wild-type anti-apoptosis inhibitor in mammalian cell cultures

artículo científico publicado en 2003

A green light for engineered algae: redirecting metabolism to fuel a biotechnology revolution

artículo científico publicado en 2008

A mathematical model of N-linked glycosylation

artículo científico publicado en 2005

A mathematical model to derive N-glycan structures and cellular enzyme activities from mass spectrometric data

artículo científico publicado en 2009

A multi-pronged investigation into the effect of glucose starvation and culture duration on fed-batch CHO cell culture

artículo científico publicado en 2015

A novel microRNA mmu‐miR‐466h affects apoptosis regulation in mammalian cells ⬇️

artículo científico publicado el 11 de marzo de 2011

A novel sugar analog enhances sialic acid production and biotherapeutic sialylation in CHO cells.

artículo científico publicado en 2017

A peptide-linked recombinant glucocerebrosidase for targeted neuronal delivery: Design, production, and assessment

scientific article published on 18 January 2016

A perspective on microarrays: current applications, pitfalls, and potential uses

artículo científico publicado en 2007

A reference genome of the Chinese hamster based on a hybrid assembly strategy

article

Accelerating genome editing in CHO cells using CRISPR Cas9 and CRISPy, a web-based target finding tool

artículo científico publicado en 2014

Achieving high throughput sequencing of a cDNA library utilizing an alternative protocol for the bench top next-generation sequencing system

artículo científico publicado en 2012

An HPLC-MALDI MS method for N-glycan analyses using smaller size samples: application to monitor glycan modulation by medium conditions

artículo científico publicado en 2009

An improved colony PCR procedure for genetic screening of Chlorella and related microalgae ⬇️

artículo científico publicado el 24 de marzo de 2011

An improved in vitro and in vivo Sindbis virus expression system through host and virus engineering.

artículo científico publicado en 2009

An in vitro uniaxial stretch model for axonal injury

artículo científico publicado en 2003

An unconventional uptake rate objective function approach enhances applicability of genome-scale models for mammalian cells

scientific article published on 23 July 2019

Anaerobic digestion of lipid-extracted Auxenochlorella protothecoides biomass for methane generation and nutrient recovery.

artículo científico publicado en 2015

Analysis and metabolic engineering of lipid-linked oligosaccharides in glycosylation-deficient CHO cells

artículo científico publicado en 2010

Anti-apoptotic genes Aven and E1B-19K enhance performance of BHK cells engineered to express recombinant factor VIII in batch and low perfusion cell culture

artículo científico publicado en 2007

Antibody Glycoengineering Strategies in Mammalian Cells.

artículo científico publicado en 2018

Antigen retrieval to improve the immunocytochemistry detection of sigma-1 receptors and ER chaperones

artículo científico publicado en 2011

Application of 13C flux analysis to identify high-productivity CHO metabolic phenotypes

artículo científico publicado en 2017

Application of microarrays to identify and characterize genes involved in attachment dependence in HeLa cells

artículo científico publicado en 2006

Application of the CRISPR/Cas9 Gene Editing Method for Modulating Antibody Fucosylation in CHO Cells

artículo científico publicado en 2018

Assessment of the coordinated role of ST3GAL3, ST3GAL4 and ST3GAL6 on the α2,3 sialylation linkage of mammalian glycoproteins

artículo científico publicado en 2015

Author Correction: Environmental stimuli drive a transition from cooperation to competition in synthetic phototrophic communities

scientific article published on 01 December 2019

Aven and Bcl-xL enhance protection against apoptosis for mammalian cells exposed to various culture conditions

artículo científico publicado en 2004

Bcl-2 family in inter-organelle modulation of calcium signaling; roles in bioenergetics and cell survival

artículo científico publicado en 2014

Beta-(1 --> 4)-galactosyltransferase activity in native and engineered insect cells measured with time-resolved europium fluorescence.

artículo científico publicado en 2002

Bioprospecting of microalgae for integrated biomass production and phytoremediation of unsterilized wastewater and anaerobic digestion centrate

artículo científico publicado en 2015

Biosynthesis of human-type N-glycans in heterologous systems

artículo científico publicado en 2004

Butyrated ManNAc analog improves protein expression in Chinese hamster ovary cells.

artículo científico publicado en 2018

COVID-19 serology at population scale: SARS-CoV-2-specific antibody responses in saliva

artículo científico publicado en 2020

COVID-19 serology at population scale: SARS-CoV-2-specific antibody responses in saliva

scientific article published on 16 October 2020

Cells by design: a mini-review of targeting cell engineering using DNA microarrays

artículo científico publicado en 2008

Cellular Trafficking and Photochemical Internalization of Cell Penetrating Peptide Linked Cargo Proteins: A Dual Fluorescent Labeling Study ⬇️

artículo científico publicado el 15 de marzo de 2011

Cellular traffic cops: the interplay between lipids and proteins regulates vesicular formation, trafficking, and signaling in mammalian cells.

artículo científico publicado en 2015

Characterization of N-acetylneuraminic acid synthase isoenzyme 1 from Campylobacter jejuni

artículo científico publicado en 2004

Characterization of intact glycopeptides reveals the impact of culture media on site-specific glycosylation of EPO-Fc fusion protein generated by CHO-GS cells

scientific article published on 29 May 2019

Chemical caspase inhibitors enhance cell culture viabilities and protein titer

artículo científico publicado en 2007

Chinese hamster genome database: an online resource for the CHO community at www.CHOgenome.org

artículo científico publicado en 2011

Combinatorial genome and protein engineering yields monoclonal antibodies with hypergalactosylation from CHO cells.

artículo científico publicado en 2017

Combining Butyrated ManNAc with Glycoengineered CHO Cells Improves EPO Glycan Quality and Production

scientific article published on 08 October 2018

Combining caspase and mitochondrial dysfunction inhibitors of apoptosis to limit cell death in mammalian cell cultures

artículo científico publicado en 2006

Combining high‐throughput screening of caspase activity with anti‐apoptosis genes for development of robust CHO production cell lines ⬇️

artículo científico publicado el 1 de septiembre de 2010

Comparative analyses of three Chlorella species in response to light and sugar reveal distinctive lipid accumulation patterns in the Microalga C. sorokiniana

artículo científico publicado en 2014

Comparing N-glycan processing in mammalian cell lines to native and engineered lepidopteran insect cell lines

artículo científico publicado en 2004

Comparison of biomass and lipid production under ambient carbon dioxide vigorous aeration and 3% carbon dioxide condition among the lead candidate Chlorella strains screened by various photobioreactor scales

artículo científico publicado en 2015

Complex-type biantennary N-glycans of recombinant human transferrin from Trichoplusia ni insect cells expressing mammalian [beta]-1,4-galactosyltransferase and [beta]-1,2-N-acetylglucosaminyltransferase II.

artículo científico publicado en 2002

Comprehensive Glycoproteomic Analysis of Chinese Hamster Ovary Cells

scientific article published on 03 December 2018

Continuous production process of retroviral vector for adoptive T- cell therapy

artículo científico publicado en 2018

Controlling Apoptosis to Optimize Yields of Proteins from Mammalian Cells ⬇️

artículo científico publicado el 1 de enero de 2012

Controlling N-linked glycan site occupancy

artículo científico publicado en 2005

Conversion of MDCK cell line to suspension culture by transfecting with human siat7e gene and its application for influenza virus production

scientific article published on 17 August 2009

Coupling enrichment methods with proteomics for understanding and treating disease

artículo científico publicado en 2015

Design and Production of Bispecific Antibodies

artículo científico publicado en 2019

Directed evolution of mammalian anti-apoptosis proteins by somatic hypermutation ⬇️

artículo científico publicado el 9 de diciembre de 2011

DmSAS is required for sialic acid biosynthesis in cultured Drosophila third instar larvae CNS neurons

artículo científico publicado en 2011

Durable SARS-CoV-2 B cell immunity after mild or severe disease

artículo científico publicado en 2020

E2F-1 overexpression increases viable cell density in batch cultures of Chinese hamster ovary cells

artículo científico publicado en 2008

Early prediction of instability of chinese hamster ovary cell lines expressing recombinant antibodies and antibody‐fusion proteins ⬇️

artículo científico publicado el 1 de diciembre de 2011

Editorial Overview: Synthetic biology hybrids - a golden age of pathway engineering

artículo científico publicado en 2015

Egr1 and Gas6 facilitate the adaptation of HEK-293 cells to serum-free media by conferring enhanced viability and higher growth rates

artículo científico publicado en 2008

Elucidating the impact of cottonseed hydrolysates on CHO cell culture performance through transcriptomic analysis

artículo científico publicado en 2020

Elucidation of the CHO Super-Ome (CHO-SO) by Proteoinformatics.

artículo científico publicado en 2015

Engineering Sialic Acid Synthesis Ability in Insect Cells

artículo científico publicado en 2015

Engineering cells to improve protein expression

artículo científico publicado en 2014

Engineering intracellular CMP-sialic acid metabolism into insect cells and methods to enhance its generation

artículo científico publicado en 2005

Engineering sialic acid synthetic ability into insect cells: identifying metabolic bottlenecks and devising strategies to overcome them

artículo científico publicado en 2003

Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cells

artículo científico publicado en 2007

Enhanced transient recombinant protein production in CHO cells through the co-transfection of the product gene with Bcl-xL.

artículo científico publicado en 2014

Enhancement of cell proliferation in various mammalian cell lines by gene insertion of a cyclin-dependent kinase homolog

artículo científico publicado en 2007

Enhancement of transient gene expression and culture viability using Chinese hamster ovary cells overexpressing Bcl-x(L).

artículo científico publicado en 2008

Environmental stimuli drive a transition from cooperation to competition in synthetic phototrophic communities

artículo científico publicado en 2019

Evidence for a mutualistic relationship between the cyanobacteria Nostoc and fungi Aspergilli in different environments

artículo científico publicado en 2020

Expanded Chinese hamster organ and cell line proteomics profiling reveals tissue-specific functionalities

scientific article published on 28 September 2020

Exploiting the proteomics revolution in biotechnology: from disease and antibody targets to optimizing bioprocess development

artículo científico publicado en 2014

Expression of a functional Drosophila melanogaster CMP-sialic acid synthetase. Differential localization of the Drosophila and human enzymes

artículo científico publicado en 2006

Expression of a functional Drosophila melanogaster N-acetylneuraminic acid (Neu5Ac) phosphate synthase gene: evidence for endogenous sialic acid biosynthetic ability in insects

artículo científico publicado en 2002

Expression of anti-apoptosis genes alters lactate metabolism of Chinese Hamster Ovary cells in culture

artículo científico publicado en 2009

False positive reactivity of recombinant, diagnostic, glycoproteins produced in High Five insect cells: effect of glycosylation

artículo científico publicado en 2007

Feast or famine: autophagy control and engineering in eukaryotic cell culture

scientific article published on 16 September 2008

Genome Sequence of the Oleaginous Green Alga, Chlorella vulgaris UTEX 395.

artículo científico publicado en 2018

Genome-Scale Metabolic Model for the Green Alga Chlorella vulgaris UTEX 395 Accurately Predicts Phenotypes under Autotrophic, Heterotrophic, and Mixotrophic Growth Conditions.

artículo científico publicado en 2016

Genome-Wide High-Throughput RNAi Screening for Identification of Genes Involved in Protein Production

artículo científico publicado en 2018

Genome-scale RNA interference screen identifies antizyme 1 (OAZ1) as a target for improvement of recombinant protein production in mammalian cells

artículo científico publicado en 2016

Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion

Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion

scientific article published on 02 January 2020

Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome

artículo científico publicado en 2013

Glucose depletion activates mmu-miR-466h-5p expression through oxidative stress and inhibition of histone deacetylation

artículo científico publicado en 2012

GlycoFish: A Database of Zebrafish N-linked Glycoproteins Identified Using SPEG Method Coupled with LC/MS ⬇️

artículo científico publicado el 8 de junio de 2011

GlycoFly: A Database of Drosophila N-linked Glycoproteins Identified Using SPEG–MS Techniques ⬇️

artículo científico publicado el 25 de abril de 2011

Glycoengineering of CHO Cells to Improve Product Quality

artículo científico publicado en 2017

Glycoengineering of Chinese hamster ovary cells for enhanced erythropoietin N-glycan branching and sialylation

artículo científico publicado en 2015

Glycoengineering of Mammalian Expression Systems on a Cellular Level

artículo científico publicado en 2018

Glycoproteomic and glycomic databases

artículo científico publicado en 2014

High-throughput screening and selection of mammalian cells for enhanced protein production

artículo científico publicado en 2016

Humanization of lepidopteran insect-cell-produced glycoproteins

artículo científico publicado en 2003

Identifying HIPK1 as Target of miR-22-3p Enhancing Recombinant Protein Production From HEK 293 Cell by Using Microarray and HTP siRNA Screen

artículo científico publicado en 2017

Improved protein expression in HEK293 cells by over-expressing miR-22 and knocking-out its target gene, HIPK1

scientific article published on 16 August 2019

Increased expression of the integral membrane protein ErbB2 in Chinese hamster ovary cells expressing the anti-apoptotic gene Bcl-xL.

artículo científico publicado en 2009

Increased expression of the integral membrane proteins EGFR and FGFR3 in anti-apoptotic Chinese hamster ovary cell lines

artículo científico publicado en 2012

Inhibiting apoptosis in mammalian cell culture using the caspase inhibitor XIAP and deletion mutants

artículo científico publicado en 2002

Inhibiting the apoptosis pathway using MDM2 in mammalian cell cultures

artículo científico publicado en 2007

Integrated Genome and Protein Editing Swaps α-2,6 Sialylation for α-2,3 Sialic Acid on Recombinant Antibodies from CHO.

artículo científico publicado en 2016

Integration of the transcriptome and glycome for identification of glycan cell signatures

artículo científico publicado en 2013

Karyotype variation of CHO host cell lines over time in culture characterized by chromosome counting and chromosome painting.

artículo científico publicado en 2017

Large-scale screening identifies a novel microRNA, miR-15a-3p, which induces apoptosis in human cancer cell lines

artículo científico publicado en 2013

Life and death in mammalian cell culture: strategies for apoptosis inhibition

artículo científico publicado en 2004

Links between metabolism and apoptosis in mammalian cells: applications for anti-apoptosis engineering

artículo científico publicado en 2007

Mcl-1 overexpression leads to higher viabilities and increased production of humanized monoclonal antibody in Chinese hamster ovary cells

artículo científico publicado en 2009

Measurement of sialic acid content on recombinant membrane proteins ⬇️

artículo científico publicado el 22 de noviembre de 2011

Metabolic engineering II. Eukaryotic systems

artículo científico publicado en 2002

Metabolic engineering challenges of extending N-glycan pathways in Chinese hamster ovary cells

artículo científico publicado en 2020

Metabolic engineering in the 21st century: meeting global challenges of sustainability and health

artículo científico publicado en 2008

Methods for Using Small Non-Coding RNAs to Improve Recombinant Protein Expression in Mammalian Cells

artículo científico publicado en 2018

MiRNA mimic screen for improved expression of functional neurotensin receptor from HEK293 cells

artículo científico publicado en 2015

Microfluidic bubbler facilitates near complete mass transfer for sustainable multiphase and microbial processing

artículo científico publicado en 2016

Mimicking lichens: incorporation of yeast strains together with sucrose-secreting cyanobacteria improves survival, growth, ROS removal, and lipid production in a stable mutualistic co-culture production platform

scientific article published on 21 March 2017

Mineral and non-carbon nutrient utilization and recovery during sequential phototrophic-heterotrophic growth of lipid-rich algae.

artículo científico publicado en 2014

Model-based analysis of N-glycosylation in Chinese hamster ovary cells

artículo científico publicado en 2017

Modeling of nitrogen fixation and polymer production in the heterotrophic diazotroph Azotobacter vinelandii DJ

scientific article published on 30 May 2020

Molecular Cloning and Characterization of a Novel α-Amylase from Antarctic Sea Ice Bacterium Pseudoalteromonas sp. M175 and Its Primary Application in Detergent

artículo científico publicado en 2018

Multi-tissue computational modeling analyzes pathophysiology of type 2 diabetes in MKR mice

artículo científico publicado en 2014

N-Glycosylation of IgG and IgG-Like Recombinant Therapeutic Proteins: Why Is It Important and How Can We Control It?

scientific article published on 16 March 2020

N-glycan structures of human transferrin produced by Lymantria dispar (gypsy moth) cells using the LdMNPV expression system

artículo científico publicado en 2003

One-Step Enrichment of Intact Glycopeptides From Glycoengineered Chinese Hamster Ovary Cells

artículo científico publicado en 2020

Optimization of tetracycline-responsive recombinant protein production and effect on cell growth and ER stress in mammalian cells

artículo científico publicado en 2005

Pac-Man for biotechnology: co-opting degrons for targeted protein degradation to control and alter cell function

artículo científico

Partners for life: building microbial consortia for the future

artículo científico publicado en 2020

Physiologic and pathophysiologic consequences of altered sialylation and glycosylation on ion channel function

artículo científico publicado en 2014

Physiological evaluation of a new Chlorella sorokiniana isolate for its biomass production and lipid accumulation in photoautotrophic and heterotrophic cultures ⬇️

artículo científico publicado el 2 de marzo de 2012

Phytoremediation of agriculture runoff by filamentous algae poly-culture for biomethane production, and nutrient recovery for secondary cultivation of lipid generating microalgae

artículo científico publicado en 2016

Polyprenyl lipid synthesis in mammalian cells expressing human cis-prenyl transferase

artículo científico publicado en 2005

Predicting dynamic metabolic demands in the photosynthetic eukaryote Chlorella vulgaris.

artículo científico publicado en 2017

Production and N-glycan analysis of secreted human erythropoietin glycoprotein in stably transfected Drosophila S2 cells

artículo científico publicado en 2005

Production and antigenic properties of influenza virus from suspension MDCK-siat7e cells in a bench-scale bioreactor ⬇️

artículo científico publicado el 26 de agosto de 2010

Production of lipid-containing algal-bacterial polyculture in wastewater and biomethanation of lipid extracted residues: Enhancing methane yield through hydrothermal pretreatment and relieving solvent toxicity through co-digestion

scientific article published on 06 November 2018

Proliferation and pluripotency of human embryonic stem cells maintained on type I collagen

artículo científico publicado en 2010

Proline-Rich Chaperones Are Compared Computationally and Experimentally for Their Abilities to Facilitate Recombinant Butyrylcholinesterase Tetramerization in CHO Cells

artículo científico publicado en 2017

Protein and genome evolution in Mammalian cells for biotechnology applications

artículo científico publicado en 2009

Proteomic analysis of Chinese hamster ovary cells

artículo científico publicado en 2012

Purification, characterization, and cloning of a Spodoptera frugiperda Sf9 beta-N-acetylhexosaminidase that hydrolyzes terminal N-acetylglucosamine on the N-glycan core

artículo científico publicado en 2006

QUANTITY: An Isobaric Tag for Quantitative Glycomics

artículo científico publicado en 2015

Recombinant Antibody Production in CHO and NS0 Cells: Differences and Similarities

artículo científico publicado en 2018

Sequencing the CHO DXB11 genome reveals regional variations in genomic stability and haploidy

artículo científico publicado en 2015

Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population

artículo científico publicado en 2020

Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population

artículo científico publicado en 2020

SnapShot: N-Glycosylation Processing Pathways across Kingdoms

artículo científico publicado en 2017

Stable Ectopic Expression of ST6GALNAC5 Induces Autocrine MET Activation and Anchorage-Independence in MDCK Cells

artículo científico publicado en 2016

Stable inhibition of mmu-miR-466h-5p improves apoptosis resistance and protein production in CHO cells

artículo científico publicado en 2013

Strategies for Engineering Protein N-Glycosylation Pathways in Mammalian Cells

artículo científico

Structure and synthesis of polyisoprenoids used in N-glycosylation across the three domains of life

artículo científico publicado en 2009

Study of caspase inhibitors for limiting death in mammalian cell culture

artículo científico publicado en 2003

Synergistic co-digestion of wastewater grown algae-bacteria polyculture biomass and cellulose to optimize carbon-to-nitrogen ratio and application of kinetic models to predict anaerobic digestion energy balance

scientific article published on 21 August 2018

Synthetic microbial communities of heterotrophs and phototrophs facilitate sustainable growth

scientific article published on 30 July 2020

Systems Glycobiology: Integrating Glycogenomics, Glycoproteomics, Glycomics, and Other 'Omics Data Sets to Characterize Cellular Glycosylation Processes

artículo científico publicado en 2016

Tat-tetanus toxin fragment C: a novel protein delivery vector and its use with photochemical internalization

artículo científico publicado en 2013

The Importance and Future of Biochemical Engineering

scientific article published on 28 April 2020

The beta-3 adrenergic agonist (CL-316,243) restores the expression of down-regulated fatty acid oxidation genes in type 2 diabetic mice

artículo científico publicado en 2015

The effect of iron on growth, lipid accumulation, and gene expression profile of the freshwater microalga Chlorella sorokiniana.

artículo científico publicado en 2014

The effect of mixotrophy on microalgal growth, lipid content, and expression levels of three pathway genes in Chlorella sorokiniana ⬇️

artículo científico publicado el 23 de junio de 2011

The effects of BclXL and Bax over-expression on stretch-injury induced neural cell death

artículo científico publicado en 2004

The effects of alternative pretreatment strategies on anaerobic digestion and methane production from different algal strains

artículo científico publicado en 2014

The emerging CHO systems biology era: harnessing the 'omics revolution for biotechnology

artículo científico publicado en 2013

The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line

artículo científico publicado en 2011

The impact of anti-apoptotic gene Bcl-2∆ expression on CHO central metabolism.

artículo científico publicado en 2014

The impact of sialylation linkage-type on the pharmacokinetics of recombinant butyrylcholinesterases

artículo científico publicado en 2019

The non-apoptotic action of Bcl-xL: regulating Ca(2+) signaling and bioenergetics at the ER-mitochondrion interface.

artículo científico publicado en 2016

Transcriptome and proteome analysis of Chinese hamster ovary cells under low temperature and butyrate treatment

artículo científico publicado en 2009

Transient and stable expression of the neurotensin receptor NTS1: a comparison of the baculovirus-insect cell and the T-REx-293 expression systems

artículo científico publicado en 2013

Ultra-deep next generation mitochondrial genome sequencing reveals widespread heteroplasmy in Chinese hamster ovary cells

artículo científico publicado en 2017

Uncovering the Role of N-Acetyl-Aspartyl-Glutamate as a Glutamate Reservoir in Cancer

artículo científico publicado en 2019

Utilizing genome-scale models to optimize nutrient supply for sustained algal growth and lipid productivity

scientific article published on 24 September 2019

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