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'Optimising PharmacoTherapy In the multimorbid elderly in primary CAre' (OPTICA) to improve medication appropriateness: study protocol of a cluster randomised controlled trial

artículo científico publicado en 2019

A high Gas6 level in plasma predicts venous thromboembolism recurrence, major bleeding and mortality in the elderly: a prospective multicenter cohort study

artículo científico publicado en 2019

Abdominal aortic calcification and risk of fracture among older women - The SOF study.

artículo científico publicado en 2015

Anticoagulation quality and clinical outcomes in multimorbid elderly patients with acute venous thromboembolism

artículo científico publicado en 2019

Aspirin use for the primary prevention of coronary heart disease in older adults

artículo científico publicado en 2005

Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism

scientific article published on 30 October 2019

Association between computed tomography obstruction index and mortality in elderly patients with acute pulmonary embolism: A prospective validation study

artículo científico publicado en 2017

Association between income and control of cardiovascular risk factors after acute coronary syndromes: an observational study

scientific article published on 17 April 2019

Association between insurance status, anticoagulation quality, and clinical outcomes in patients with acute venous thromboembolism

scientific article published on 12 November 2018

Association between resistin levels and cardiovascular disease events in older adults: The health, aging and body composition study

artículo científico publicado en 2015

Association between subclinical thyroid dysfunction and change in bone mineral density in prospective cohorts

artículo científico publicado en 2017

Association of Thyroid Hormone Therapy With Quality of Life and Thyroid-Related Symptoms in Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-analysis

artículo científico publicado en 2018

Association of electrocardiogram abnormalities and incident heart failure events

artículo científico publicado en 2014

Association of major and minor ECG abnormalities with coronary heart disease events

artículo científico publicado en 2012

Associations of obesity and body fat distribution with incident atrial fibrillation in the biracial health aging and body composition cohort of older adults

artículo científico publicado en 2015

Blood pressure in relation to frailty in older adults: A population-based study

scientific article published on 29 October 2019

Chronic symptoms in a representative sample of community-dwelling older people: a cross-sectional study in Switzerland

artículo científico publicado en 2017

Circulating FABP4 is a prognostic biomarker in patients with acute coronary syndrome but not in asymptomatic individuals

artículo científico publicado en 2015

Clinical impact of a structured secondary cardiovascular prevention program following acute coronary syndromes: A prospective multicenter healthcare intervention

article

Clinical presentation and outcomes in elderly patients with symptomatic isolated subsegmental pulmonary embolism

scientific article published on 22 October 2019

Comparison of 2 frailty indexes for prediction of falls, disability, fractures, and death in older women

artículo científico publicado en 2008

Control of cardiovascular risk factors and health behaviors in patients post acute coronary syndromes eligible for protein convertase subtilisin/kexin-9 inhibitors

scientific article published on 09 October 2019

Corticosteroid treatment for community-acquired pneumonia--the STEP trial: study protocol for a randomized controlled trial

artículo científico publicado en 2014

Cosyntropin testing does not predict response to glucocorticoids in community-acquired pneumonia in a randomized controlled trial

scientific article published on 09 January 2019

Cysteine-rich angiogenic inducer 61 (Cyr61): a novel soluble biomarker of acute myocardial injury improves risk stratification after acute coronary syndromes

artículo científico publicado en 2017

De-implementing wisely: developing the evidence base to reduce low-value care

scientific article published on 06 February 2020

Decreased phosphatidylcholine plasmalogens--A putative novel lipid signature in patients with stable coronary artery disease and acute myocardial infarction

artículo científico publicado en 2016

Design of the Swiss Atrial Fibrillation Cohort Study (Swiss-AF): structural brain damage and cognitive decline among patients with atrial fibrillation

artículo científico publicado en 2017

Development of a core outcome set for medication review in older patients with multimorbidity and polypharmacy: a study protocol

artículo científico publicado en 2017

Development of a standardized chart review method to identify drug-related hospital admissions in older people

artículo científico publicado en 2018

Do Factor V Leiden and Prothrombin G20210A Mutations Predict Recurrent Venous Thromboembolism in Older Patients?

artículo científico publicado en 2017

Echocardiography does not predict mortality in hemodynamically stable elderly patients with acute pulmonary embolism.

artículo científico

Educational Level, Anticoagulation Quality, and Clinical Outcomes in Elderly Patients with Acute Venous Thromboembolism: A Prospective Cohort Study

artículo científico publicado en 2016

Electrocardiographic PR interval and adverse outcomes in older adults: the Health, Aging, and Body Composition study

artículo científico publicado en 2012

Elevated HbA1c is not associated with recurrent venous thromboembolism in the elderly, but with all-cause mortality- the SWEETCO 65+ study

artículo científico publicado en 2020

Eligibility for PCSK9 Inhibitors According to American College of Cardiology (ACC) and European Society of Cardiology/European Atherosclerosis Society (ESC/EAS) Guidelines After Acute Coronary Syndromes

artículo científico publicado en 2017

Epidemiology of incident heart failure in a contemporary elderly cohort: the health, aging, and body composition study

scientific article published on April 2009

Evidence and controversies regarding the screening for subclinical hypothyroidism in patients with cardiovascular disease

artículo científico publicado en 2016

Exercise Capacity, Heart Failure Risk, and Mortality in Older Adults: The Health ABC Study

artículo científico publicado en 2016

Expected impact of applying new 2013 AHA/ACC cholesterol guidelines criteria on the recommended lipid target achievement after acute coronary syndromes

artículo científico publicado en 2015

Frailty and risk for heart failure in older adults: the health, aging, and body composition study

artículo científico publicado en 2013

Frailty and risk of falls, fracture, and mortality in older women: the study of osteoporotic fractures

artículo científico publicado en 2007

Framingham risk score and alternatives for prediction of coronary heart disease in older adults

artículo científico publicado en 2012

Frequency of use and acceptability of clinical prediction rules for pulmonary embolism among Swiss general internal medicine residents.

artículo científico publicado en 2017

Gut microbiota-dependent trimethylamine N-oxide in acute coronary syndromes: a prognostic marker for incident cardiovascular events beyond traditional risk factors

artículo científico publicado en 2017

Gut microbiota-dependent trimethylamine-N-oxide (TMAO) shows a U-shaped association with mortality but not with recurrent venous thromboembolism

artículo científico publicado en 2018

Health utility indexes in patients with acute coronary syndromes

artículo científico publicado en 2016

Health-related quality of life in patients with atrial fibrillation: The role of symptoms, comorbidities, and the type of atrial fibrillation

artículo científico publicado en 2019

High-value, data-informed, and team-based care for multimorbidity

artículo científico publicado en 2020

How general practitioners would deprescribe in frail oldest-old with polypharmacy - the LESS study

artículo científico publicado en 2018

How to prevent overdiagnosis

artículo científico publicado en 2015

Impact of Inflammation on the Relationship Among Alcohol Consumption, Mortality, and Cardiac Events

Impact of Thyroid Hormone Therapy on Atherosclerosis in the Elderly With Subclinical Hypothyroidism: A Randomized Trial

artículo científico publicado en 2018

Improved risk stratification of patients with acute coronary syndromes using a combination of hsTnT, NT-proBNP and hsCRP with the GRACE score

artículo científico publicado en 2016

Improving inappropriate medication and information transfer at hospital discharge: study protocol for a cluster RCT

artículo científico publicado en 2018

Incident heart failure prediction in the elderly: the health ABC heart failure score

artículo científico publicado en 2008

Individualised nutritional support in medical inpatients at nutritional risk: a randomised clinical trial

scientific article published on 25 April 2019

Inflammation during acute coronary syndromes - Risk of cardiovascular events and bleeding

scientific article published on 27 March 2019

Inflammatory markers and incident heart failure risk in older adults: the Health ABC (Health, Aging, and Body Composition) study

artículo científico publicado en 2010

Initial evaluation of thyroid dysfunction - Are simultaneous TSH and fT4 tests necessary?

artículo científico publicado en 2018

Intensified lipid lowering using ezetimibe after publication of the IMPROVE-IT trial: A contemporary analysis from the SPUM-ACS cohort

scientific article published on 10 December 2019

International core outcome set for clinical trials of medication review in multi-morbid older patients with polypharmacy.

artículo científico publicado en 2018

International variation in GP treatment strategies for subclinical hypothyroidism in older adults: a case-based survey

artículo científico publicado en 2015

Lessons from the Swiss Medical Board recommendation against mammography screening programs

artículo científico publicado en 2014

Letter by Löwe et al Regarding Article, "Low-Density Lipoprotein Cholesterol Lowering for the Primary Prevention of Cardiovascular Disease Among Men With Primary Elevations of Low-Density Lipoprotein Cholesterol Levels of 190 mg/dL or Above: Analyse

artículo científico publicado en 2018

Long-term outcomes of elderly patients with CYP2C9 and VKORC1 variants treated with vitamin K antagonists.

artículo científico publicado en 2017

Loss of Sirt3 accelerates arterial thrombosis by increasing formation of neutrophil extracellular traps and plasma tissue factor activity.

artículo científico publicado en 2018

Low statin use in adults hospitalized with acute coronary syndrome

artículo científico publicado en 2015

Low thyroid function is not associated with an accelerated deterioration in renal function.

artículo científico publicado en 2018

Lung function and risk for heart failure among older adults: the Health ABC Study

artículo científico publicado en 2011

Markers of atherosclerosis and inflammation for prediction of coronary heart disease in older adults

artículo científico publicado en 2010

Metabolic syndrome and the risk of cardiovascular disease in older adults

artículo científico publicado en 2006

Mortality associated with diabetes and cardiovascular disease in older women.

artículo científico publicado en 2012

Multimorbidity and quality of preventive care in Swiss university primary care cohorts.

artículo científico publicado en 2014

New concepts in the management of dyslipidaemiaa.

artículo científico publicado en 2016

Normal Thyroid Function and the Risk of Atrial Fibrillation: the Rotterdam Study

artículo científico publicado en 2015

Nutritional risk screening (NRS 2002) is a strong and modifiable predictor risk score for short-term and long-term clinical outcomes: secondary analysis of a prospective randomised trial

scientific article published on 14 December 2019

Obesity is not associated with recurrent venous thromboembolism in elderly patients: Results from the prospective SWITCO65+ cohort study.

artículo científico publicado en 2017

Omega-3 fatty acids predict recurrent venous thromboembolism or total mortality in elderly patients with acute venous thromboembolism.

artículo científico publicado en 2016

Overdiagnosis and overtreatment of thyroid cancer: A population-based temporal trend study

artículo científico publicado en 2017

Patient Characteristics and General Practitioners' Advice to Stop Statins in Oldest-Old Patients: a Survey Study Across 30 Countries

scientific article published on 16 January 2019

Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol

artículo científico publicado en 2016

Polypharmacy is associated with an increased risk of bleeding in elderly patients with venous thromboembolism

artículo científico publicado en 2014

Pre-hospital alarm activation for STEMI patients undergoing primary percutaneous coronary intervention in the era of transradial procedures

artículo científico publicado en 2016

Prediction of short-term prognosis in elderly patients with acute pulmonary embolism: validation of the RIETE score.

artículo científico publicado en 2018

Predictors and Causes of Long-Term Mortality in Elderly Patients with Acute Venous Thromboembolism: A Prospective Cohort Study

artículo científico publicado en 2016

Predictors and Outcomes of Recurrent Venous Thromboembolism in Elderly Patients.

artículo científico publicado en 2018

Prefrailty and Chronic Morbidity in the Youngest Old: An Insight from the Lausanne Cohort Lc65+

artículo científico publicado el 20 de agosto de 2012

Prevalence and management of familial hypercholesterolaemia in patients with acute coronary syndromes

artículo científico publicado en 2015

Prevalence of potentially inappropriate prescribing in a subpopulation of older European clinical trial participants: a cross-sectional study.

artículo científico publicado en 2018

Profiling and validation of circulating microRNAs for cardiovascular events in patients presenting with ST-segment elevation myocardial infarction

artículo científico publicado en 2016

Prognosis of Patients With Familial Hypercholesterolemia After Acute Coronary Syndromes

artículo científico publicado en 2016

Prognosis of Patients with Chronic and Hospital-Acquired Anaemia After Acute Coronary Syndromes

scientific article published on 25 November 2019

Prognosis of cardiovascular and non-cardiovascular multimorbidity after acute coronary syndrome.

artículo científico publicado en 2018

Prognostic Value of SYNTAX Score II in Patients with Acute Coronary Syndromes Referred for Invasive Management: A Subanalysis from the SPUM and COMFORTABLE AMI Cohorts

Prognostic value of PCSK9 levels in patients with acute coronary syndromes

artículo científico publicado en 2015

Prognostic value of elevated lipoprotein(a) in patients with acute coronary syndromes

scientific article published on 07 May 2019

Prognostic value of pulse pressure after an acute coronary syndrome

artículo científico publicado en 2018

Prognostic value of total testosterone levels in patients with acute coronary syndromes

scientific article published on 01 June 2019

Quality of care after acute coronary syndromes in a prospective cohort with reasons for non-prescription of recommended medications

artículo científico publicado en 2014

Rationale and design of OPtimising thERapy to prevent Avoidable hospital admissions in Multimorbid older people (OPERAM): a cluster randomised controlled trial

artículo científico publicado en 2019

Reasons for discontinuation of recommended therapies according to the patients after acute coronary syndromes

artículo científico publicado en 2015

Recent incidence and surgery trends for prostate cancer: Towards an attenuation of overdiagnosis and overtreatment?

artículo científico publicado en 2019

Relationships of Overt and Silent Brain Lesions With Cognitive Function in Patients With Atrial Fibrillation

artículo científico publicado en 2019

Response to Tomoyuki Kawada, MD: Smoking, Systolic Blood Pressure, Fasting Plasma Glucose and Progression of Carotid Atherosclerosis.

artículo científico publicado en 2016

Response to the Letter by Choy.

artículo científico publicado en 2017

Resting heart rate and incident heart failure and cardiovascular mortality in older adults: role of inflammation and endothelial dysfunction: the PROSPER study

artículo científico publicado en 2012

Risk stratification of elderly patients with acute pulmonary embolism

scientific article published on 16 July 2019

Safety of Prasugrel Loading Doses in Patients Pre-Loaded With Clopidogrel in the Setting of Primary Percutaneous Coronary Intervention: Results of a Nonrandomized Observational Study

artículo científico publicado en 2015

Safety profile of prasugrel and clopidogrel in patients with acute coronary syndromes in Switzerland

artículo científico publicado en 2015

Screening and treatment of hypertension in older adults: less is more?

artículo científico publicado en 2018

Serum resistin concentrations and risk of new onset heart failure in older persons: the health, aging, and body composition (Health ABC) study

scientific article published on 16 April 2009

Sex differences in the prevalence and clinical outcomes of subclinical peripheral artery disease in the Health, Aging, and Body Composition (Health ABC) study

artículo científico publicado en 2013

Sex-related electrocardiographic differences in patients with different types of atrial fibrillation: Results from the SWISS-AF study

artículo científico publicado en 2020

Skeletal Effects of Levothyroxine for Subclinical Hypothyroidism in Older Adults: A TRUST Randomized Trial Nested Study

artículo científico publicado en 2020

Statin therapy and recurrent venous thromboembolism in the elderly: a prospective cohort study

artículo científico publicado en 2019

Study protocol: a randomised controlled trial on the clinical effects of levothyroxine treatment for subclinical hypothyroidism in people aged 80 years and over

scientific article published on 19 September 2018

Study protocol; Thyroid hormone Replacement for Untreated older adults with Subclinical hypothyroidism - a randomised placebo controlled Trial (TRUST).

artículo científico publicado en 2017

Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individual Participant Data Analysis

artículo científico publicado en 2015

Subclinical Thyroid Dysfunction and Depressive Symptoms among the Elderly: A Prospective Cohort Study.

artículo científico publicado en 2015

Subclinical Thyroid Dysfunction and the Risk of Cognitive Decline: a Meta-Analysis of Prospective Cohort Studies.

artículo científico publicado en 2016

Subclinical Thyroid Dysfunction and the Risk of Heart Failure in Older Persons at High Cardiovascular Risk

scholarly article by David Nanchen et al published March 2012 in The Journal of Clinical Endocrinology and Metabolism

Subclinical hypothyroidism and functional mobility in older adults

artículo científico publicado en 2009

Subclinical hypothyroidism and the risk of heart failure, other cardiovascular events, and death

artículo científico publicado en 2005

Subclinical thyroid disorders

Subclinical thyroid dysfunction and cognitive decline in old age

artículo científico publicado en 2013

Subclinical thyroid dysfunction and depressive symptoms: protocol for a systematic review and individual participant data meta-analysis of prospective cohort studies

artículo científico publicado en 2019

Subclinical thyroid dysfunction and functional capacity among elderly.

artículo científico publicado en 2013

Subclinical thyroid dysfunction and the risk of stroke: a systematic review and meta-analysis

artículo científico

The adherence to initial processes of care in elderly patients with acute venous thromboembolism

artículo científico publicado en 2014

The joint influence of gender and amount of smoking on weight gain one year after smoking cessation

artículo científico publicado en 2014

Thrombus aspiration in acute coronary syndromes: prevalence, procedural success, change in serial troponin T levels and clinical outcomes in a contemporary Swiss cohort

artículo científico publicado en 2017

Thyroid Dysfunction and Anemia: A Prospective Cohort Study and a Systematic Review.

artículo científico publicado en 2018

Thyroid Function Tests in the Reference Range and Fracture: Individual Participant Analysis of Prospective Cohorts.

artículo científico publicado en 2017

Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis

artículo científico publicado en 2016

Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism.

artículo científico publicado en 2017

Thyroid Hormone Therapy for Subclinical Hypothyroidism-Reply

scientific article published on 01 February 2019

Thyroid function within the normal range and risk of coronary heart disease: an individual participant data analysis of 14 cohorts

artículo científico publicado en 2015

Thyroid hormone use, hyperthyroidism and mortality in older women

artículo científico publicado en 2007

Thyroid hormones treatment for subclinical hypothyroidism: a clinical practice guideline

scientific article published on 14 May 2019

Unwarranted regional variation in vertebroplasty and kyphoplasty in Switzerland: A population-based small area variation analysis

scientific article published in PLoS ONE

Uptake and efficacy of a systematic intensive smoking cessation intervention using motivational interviewing for smokers hospitalised for an acute coronary syndrome: a multicentre before-after study with parallel group comparisons.

artículo científico publicado en 2016

Usefulness of D-Dimer Testing in Predicting Recurrence in Elderly Patients with Unprovoked Venous Thromboembolism.

artículo científico publicado en 2017

Variation in treatment strategies of Swiss general practitioners for subclinical hypothyroidism in older adults

artículo científico publicado en 2015

Vitamin D deficiency is highly prevalent in malnourished inpatients and associated with higher mortality: A prospective cohort study

artículo científico publicado en 2019