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BI-2536 and BI-6727, dual Polo-like kinase/bromodomain inhibitors, effectively reactivate latent HIV-1.

artículo científico publicado en 2018

Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88.

artículo científico publicado en 2017

Cell-cell and virus-cell fusion assay-based analyses of alanine insertion mutants in the distal α9 portion of the JRFL gp41 subunit from HIV-1

scientific article published on 08 February 2019

HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains

artículo científico publicado en 2017

Identification of embryonic precursor cells that differentiate into thymic epithelial cells expressing autoimmune regulator

artículo científico publicado en 2016

Impact of spaceflight on the murine thymus and mitigation by exposure to artificial gravity during spaceflight

artículo científico publicado en 2019

Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple-negative breast cancer.

artículo científico publicado en 2017

Mint3 depletion restricts tumor malignancy of pancreatic cancer cells by decreasing SKP2 expression via HIF-1

scientific article published on 21 August 2020

Pharmacological inhibition of Mint3 attenuates tumour growth, metastasis, and endotoxic shock

artículo científico publicado en 2021

TRAF6 maintains mammary stem cells and promotes pregnancy-induced mammary epithelial cell expansion

scientific article published on 06 August 2019

The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner

artículo científico publicado en 2020

The Antimalarial Compound Atovaquone Inhibits Zika and Dengue Virus Infection by Blocking E Protein-Mediated Membrane Fusion

artículo científico publicado en 2020

The anticoagulant nafamostat potently inhibits SARS-CoV-2 infection in vitro: an existing drug with multiple possible therapeutic effects

artículo científico publicado en 2020

The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.

artículo científico publicado en 2008

The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance

artículo científico publicado en 2008

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